M. Goodhardt

In vivo replication of the hamster polyomavirus genome and generation of specific deletions in the process of lymphomagenesis.

Mazur, S, Goodhardt, M, Feunteun, J, De La Roche Saint André, C

Hamster polyomavirus (HaPV) causes lymphomas when injected into newborn hamsters. These tumors are virus-free but accumulate large amounts of deleted extrachromosomal viral genomes. In order to...

Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.

Goodhardt, M, Cavelier, P, Akimenko, M A, Lutfalla, G, Babinet, C, Rougeon, F

To determine whether a foreign unrearranged immunoglobulin gene can be functionally rearranged and expressed in vivo, a rabbit b9 kappa light chain gene construct containing a single germ-line kappa...

A rapid test for V(D)J recombinase activity.

Kallenbach, S, Goodhardt, M, Rougeon, F

Immunoglobulin kappa light chain gene promoter and enhancer are not responsible for B-cell restricted gene rearrangement.

Goodhardt, M, Babinet, C, Lutfalla, G, Kallenbach, S, Cavelier, P, Rougeon, F

We have produced transgenic mice which synthesize chimeric mouse-rabbit immunoglobulin (Ig) kappa light chains following in vivo recombination of an injected unrearranged kappa gene. The exogenous...

Does the guanine nucleotide regulatory protein Ni mediate progesterone inhibition of Xenopus oocyte adenylate cyclase?

Goodhardt, M, Ferry, N, Buscaglia, M, Baulieu, E E, Hanoune, J

In Xenopus laevis oocytes progesterone is able to inhibit directly the plasma membrane adenylate cyclase activity and induce reinitiation of meiotic maturation. To determine whether progesterone...

In vivo replication of the hamster polyomavirus genome and generation of specific deletions in the process of lymphomagenesis.

Mazur, S, Goodhardt, M, Feunteun, J, De La Roche Saint André, C

Hamster polyomavirus (HaPV) causes lymphomas when injected into newborn hamsters. These tumors are virus-free but accumulate large amounts of deleted extrachromosomal viral genomes. In order to...

Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.

Goodhardt, M, Cavelier, P, Akimenko, M A, Lutfalla, G, Babinet, C, Rougeon, F

To determine whether a foreign unrearranged immunoglobulin gene can be functionally rearranged and expressed in vivo, a rabbit b9 kappa light chain gene construct containing a single germ-line kappa...

A rapid test for V(D)J recombinase activity.

Kallenbach, S, Goodhardt, M, Rougeon, F

Immunoglobulin kappa light chain gene promoter and enhancer are not responsible for B-cell restricted gene rearrangement.

Goodhardt, M, Babinet, C, Lutfalla, G, Kallenbach, S, Cavelier, P, Rougeon, F

We have produced transgenic mice which synthesize chimeric mouse-rabbit immunoglobulin (Ig) kappa light chains following in vivo recombination of an injected unrearranged kappa gene. The exogenous...

Does the guanine nucleotide regulatory protein Ni mediate progesterone inhibition of Xenopus oocyte adenylate cyclase?

Goodhardt, M, Ferry, N, Buscaglia, M, Baulieu, E E, Hanoune, J

In Xenopus laevis oocytes progesterone is able to inhibit directly the plasma membrane adenylate cyclase activity and induce reinitiation of meiotic maturation. To determine whether progesterone...

Binding of yohimbine stereoisomers to alpha-adrenoceptors in rat liver and human platelets.

Ferry, N., Goodhardt, M., Hanoune, J., Sevenet, T.

1--Displacement of tritiated prazosin binding to rat liver plasma membranes and tritiated yohimbine human platelet membranes shows that (+)-yohimbine, alloyohimbine and alpha-yohimbine (rauwolscine)...