Holleman, A., Cheng, C., Pui, C.H., Evans, W.E., Relling, M.V., Pieters, R., ...
BACKGROUND: Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percent of patients. However, the cause of treatment failure in the remaining 20 percent of...
Panetta, J C, Evans, W E, Cheok, M H
The antimetabolite mercaptopurine (MP) is widely used to treat childhood acute lymphoblastic leukaemia (ALL). To study the dynamics of MP on the cell cycle, we incubated human T-cell leukaemia cell...