Energy spectra of cosmic-ray nuclei at high energies (2009)
Ahn, H. S., Allison, P., Bagliesi, M. G., Barbier, L., Beatty, J. J., Bigongiari, G., ...
We present new measurements of the energy spectra of cosmic-ray (CR) nuclei from the second flight of the balloon-borne experiment Cosmic Ray Energetics And Mass (CREAM). The instrument included...
A Comprehensive Study of Inversion Current in MOS Tunneling Diodes (2009)
M. H. Lee, C. W. Liu, Senior Member
Abstract—The gate current of MOS tunneling diodes biased at inversion region with different substrate doping is investigated. For p-type substrate (1–5-cm) devices, the tunneling diode works in...
Novel Methods to Incorporate Deuterium in the MOS Structures (2009)
M. H. Lee, C. W. Liu, Senior Member
Abstract—The deuterium concentration as high as 2 10 PH cm Q can be incorporated in rapid thermal oxide layers by a process of deuterium prebake and deuterium post oxidation anneal. The deuterium...
Abdelwahab, A., Gardner, M., Parkash, R., Basta, M., Sapp, J., Veltmann, C., ...
Introduction: Scar-related ventricular tachycardia (VT) is often unmappable. Data regarding the outcomes of ablation for mappable vs unmappable VT are lacking. Methods: Catheter ablation of...
Haffty, B. G., Choi, D. H., Goyal, S., Silber, A., Ranieri, K., Matloff, E., ...
Background: Despite significant differences in age of onset and incidence of breast cancer between Caucasian (CA), African-American (AA) and Korean (KO) women, little is known about differences in...
Roughness-Enhanced Reliability of MOS Tunneling Diodes (2008)
Student Member, F. Yuan, Student Member, ...
Abstract—Both electrical and optical reliabilities of PMOS and NMOS tunneling diodes are enhanced by oxide roughness, prepared by very high vacuum prebake technology. For the rough PMOS devices, as...
C. J. Price, L. Travé-massuyès, R. Milne, L. Ironi, B. Bredeweg, M. H. Lee, ...
This paper considers where the QR field might be in twenty years time, outlining five areas where developments in model-based systems in general, and qualitative reasoning in particular might have a...
Ahn, H. S., Allison, P. S., Bagliesi, M. G., Beatty, J. J., Bigongiari, G., Boyle, P. J., ...
We present new measurements of heavy cosmic-ray nuclei at high energies per- formed during the first flight of the balloon-borne cosmic-ray experiment CREAM (Cosmic-Ray Energetics And Mass). This...
Abe, K., Fuke, H., Haino, S., Hams, T., Itazaki, A., Kim, K. C., ...
The BESS-Polar spectrometer had its first successful balloon flight over Antarctica in December 2004. During the 8.5-day long-duration flight, almost 0.9 billion events were recorded and 1,520...
Design Issues for Assistive Robotics for the Elderly (2008)
The worldwide population of elderly people is growing rapidly and in the coming decades the proportion of older people in the developed countries will change significantly. This demographic shift...
DOI: 10.1017/S000000000000000 Printed in the United Kingdom Qualitative Futures (2008)
C. J. Price, L. Travé-massuyès, R. Milne, L. Ironi, K. Forbus, B. Bredeweg, ...
This paper reviews the state of the art in model-based systems and qualitative reasoning, and considers where the field will be in twenty years time. It highlights six areas where developments in...
Y. B. Lee, S. W. Yoon, C. K. Lee, M. H. Lee
Abstract—We developed wearable EDA sensor gloves using conducting fabric and embedded system. EDA(Electro-dermal Activity) signal is an electric response on the skin of the human body. There are...
Qualitative modelling of unknown interface behaviour (2008)
When faced with an interface to an unknown system or device humans adopt exploratory interactive behaviour in order to gain information and insight. This paper describes a computer program which...
Microstructural Characteristics of the Fuel Cladding Tubes Irradiated in Kori Unit 1 (2008)
Kim, H.G., Baek, J.H., Lee, M.H., Chun, Y.B., Jeong, Y.H.
In order to evaluate the microstructural characteristics of irradiated fuel claddings (Zircaloy-4), two irradiated specimens having different burnups (18 GWD/MTU and 42 GWD/MTU) were prepared from...
Evaluation of Bioactivity of Ti-6Al-7Nb Alloys with Various Hydrothermal Treatment Times (2008)
Kwon, O. S., Choi, S. K., Park, K. B., Lee, M. H., Bae, T. S., Lee, O. Y.
This study was to investigate whether the bioactivity of the anodized and hydrothermally treated Ti-6Al-7Nb alloy were affected by the time of hydrothermal treatment. Anodizing was performed at...
Tensile Properties of Zr-0.4Sn-1.5Nb-0.2Fe (2008)
Lee, M. H., Kim, J. H., Choi, B. K., Jeong, Y. H.
To study the dynamic strain aging behavior of Zr-0.4Sn-1.5Nb-0.2Fe sample tube for nuclear fuel cladding in the range of pressurized water reactor (PWR) operation temperature, the tensile tests of...
Kwon, O. S., Choi, S. K., Moon, J. W., Lee, M. H., Bae, T. S., Lee, O. Y.
This study was to investigate the surface properties of electrochemically oxidized Ti-6Al-7Nb alloy by anodic spark discharge technique. Anodizing was performed at current density 30 $mA/cm^2$ up to...
Evaluation of Bioactivity of Titanium Implant Treated with $H_2O_2/HCl$ Solution (2008)
Yue, J. S., Kwon, O. S., Lee, O. Y., Lee, M. H., Song, K. H.
Surface treatment play an important role in nucleating calcium phosphate deposition on surgical Ti implant. Therefore, the purpose of this study is to examine whether the precipitation of apatite on...
CHERCAM: the Cherenkov imager of the CREAM experiment, results in Z=1 test beams (2008)
Derome, L., Barrau, A., Bazer-Bachi, R., Bourrion, O., Bouvier, J., Boyer, B., ...
The CREAM experiment investigates the high energy spectrum of nuclear elements from H to Fe in the cosmic ray flux up to $10^{15}$ eV, with an instrument designed to achieve individual elements...
CHERCAM: the Cherenkov imager of the CREAM experiment, results in Z=1 test beams (2008)
Derome, L., Barrau, A., Bazer-Bachi, R., Bourrion, O., Bouvier, J., Boyer, B., ...
The CREAM experiment investigates the high energy spectrum of nuclear elements from H to Fe in the cosmic ray flux up to $10^{15}$ eV, with an instrument designed to achieve individual elements...
CHERCAM: the Cherenkov imager of the CREAM experiment, results in Z=1 test beams (2008)
Derome, L., Barrau, A., Bazer-Bachi, R., Bourrion, O., Bouvier, J., Boyer, B., ...
The CREAM experiment investigates the high energy spectrum of nuclear elements from H to Fe in the cosmic ray flux up to $10^{15}$ eV, with an instrument designed to achieve individual elements...
New Limits on the Masses of the Selectron and Photino (2007)
Y. Sugimoto, K. Abe, Y. Fujii, S. Igarashi, Y. Kurihara, M. H. Lee, ...
A study of e + e \Gamma annihilations into final states containing a single energetic photon with no accompanying particles is made at a center of mass energy of 57.8 GeV. The measured cross section...
M. H. Lee, Lee Ngan, G. A. Crebbin, Since Ramamurthi
Vector quantization (VQ) based on a fixed block-size classification (FBSC) model, which is known as classified VQ (CVQ), offers a useful solution for the edge degradation problem of conventional...
Nuclear Counter Effect of Silicon PIN Photodiode used in (2007)
Csi Calorimeter, Belle Preprint, A. Satpathy, K. Tamai, M. Fukushima, D. Y. Kim, ...
We investigated the nuclear counter effect of the silicon PIN photodiode mounted on a CsI(T`) crystal array as a result of the leakage of electromagnetic shower through the rear end of the crystal....
Staphylococcus aureus colonization and infection in New York State Prisons (2007)
Lowry, F.D., Aiello, A.E., Bhat, M., Johnson-Lawrence, V.D., Lee, M.H., Burrell, E., ...
Peer Reviewed
Anisotropy and Penetration Depth of MgB$_{2}$ from ${}^{11}$B NMR (2006)
Chen, Bo, Sengupta, Pratim, Halperin, W. P., Sigmund, E. E., Mitrovic, V. F., Lee, M. H., ...
The ${}^{11}$B NMR spectra in polycrystalline MgB$_2$ were measured for several magnetic fields (1.97 T and 3.15 T) as a function of temperature from 5 K to 40 K. The composite spectra in the...
Quantification of surgical blood loss. (2006)
Lee, M.H., Ingvertsen, B.T., Kirpensteijn, J., Jensen, A.L., Kristensen, A.T.
Beam test calibration of the balloon-borne imaging calorimeter for the CREAM experiment (2005)
Marrocchesi, P. S., Ahn, H. S., Bagliesi, M. G., Basti, A., Bigongiari, G., Castellina, A., ...
CREAM (Cosmic Ray Energetics And Mass) is a multi-flight balloon mission designed to collect direct data on the elemental composition and individual energy spectra of cosmic rays. Two instrument...
Translational repression of C-elegans p53 by GLD-1 regulates DNA damage-induced apoptosis (2005)
Schumacher,B., Hanazawa,M., Lee,M. H., Nayak,S., Volkmann,K., Hofmann,R., ...
Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis. (2005)
Schumacher, B, Hanazawa, M, Lee, M H, Nayak, S, Volkmann, K, Hofmann, E R, ...
p53 is a tumor suppressor gene whose regulation is crucial to maintaining genome stability and for the apoptotic elimination of abnormal, potentially cancer-predisposing cells. C. elegans contains a...
A Cherenkov imager for charge measurements of Nuclear Cosmic Rays in the CREAM II instrument (2005)
Buénerd, M., Barrau, A., Bazer-Bachi, R., Borrel, V., Bourrion, O., Bouvier, J., ...
A proximity focusing Cherenkov imager for the charge measurement of nuclear cosmic rays in the CREAM II instrument, called CHERCAM, is under construction. This imager consists of a silica aerogel...
A Cherenkov imager for charge measurements of Nuclear Cosmic Rays in the CREAM II instrument (2005)
Buénerd, M., Barrau, A., Bazer-Bachi, R., Borrel, V., Bourrion, O., Bouvier, J., ...
A proximity focusing Cherenkov imager for the charge measurement of nuclear cosmic rays in the CREAM II instrument, called CHERCAM, is under construction. This imager consists of a silica aerogel...
A Cherenkov imager for charge measurements of Nuclear Cosmic Rays in the CREAM II instrument (2005)
Buénerd, M., Barrau, A., Bazer-Bachi, R., Borrel, V., Bourrion, O., Bouvier, J., ...
A proximity focusing Cherenkov imager for the charge measurement of nuclear cosmic rays in the CREAM II instrument, called CHERCAM, is under construction. This imager consists of a silica aerogel...
A Cherenkov imager for charge measurements of Nuclear Cosmic Rays in the CREAM II instrument (2005)
Buénerd, M., Barrau, A., Bazer-Bachi, R., Borrel, V., Bourrion, O., Bouvier, J., ...
A proximity focusing Cherenkov imager for the charge measurement of nuclear cosmic rays in the CREAM II instrument, called CHERCAM, is under construction. This imager consists of a silica aerogel...
A Cherenkov imager for charge measurements of Nuclear Cosmic Rays in the CREAM II instrument (2005)
Buénerd, M., Barrau, A., Bazer-Bachi, R., Borrel, V., Bourrion, O., Bouvier, J., ...
A proximity focusing Cherenkov imager for the charge measurement of nuclear cosmic rays in the CREAM II instrument, called CHERCAM, is under construction. This imager consists of a silica aerogel...
Psychologically inspired sensory-motor development in early robot learning (2005)
Abstract: We present an implementation of a model of very early sensory-motor development, guided by results from developmental psychology. Behavioural acquisition and growth is demonstrated through...
Postoperative chemoradiotherapy for gastric cancer (2003)
Park, S. H., Kim, D. Y., Heo, J. S., Lim, D. H., Park, C. K., Lee, K. W., ...
Background: We report the results of postoperative chemoradiotherapy after curative resection in gastric cancer patients. Patients and methods: Patients with gastric cancer staged IB to IV(M0) were...
Lee,M. H., Maskos,K., Knäuper,V., Dodds,P., Murphy,G.
Tumor necrosis factor-alpha (TNF-alpha) converting enzyme (TACE/ADAM-17) is responsible for the release of TNF-u, a potent proinflammatory cytokine associated with many chronic debilitating diseases...
The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3 (2002)
Lee,M. H., Verma,V., Maskos,K., Becherer,J. D., Knäuper,V., Dodds,P., ...
Tumor necrosis factor-alpha converting enzyme (TACE) is an ADAM (a disintegrin and metalloproteinases) that comprises an active catalytic domain and several C-terminal domains. We compare the binding...
Lee,M. H., Verma,V., Maskos,K., Nath,D., Knäuper,V., Dodds,P., ...
We previously reported that full-length tissue inhibitor of metallo-proteinase-3 (TIMP-3) and its N-terminal domain form (N-TIMP-3) displayed equal binding affinity for tissue necrosis factor-alpha...
Neutron beam test of CsI crystal for dark matter search (2002)
Park, H., Choi, D. H., Hahn, I. S., Hwang, M. J., Kang, W. G., Kim, H. J., ...
We have studied the response of Tl-doped and Na-doped CsI crystals to nuclear recoils and $\gamma$'s below 10 keV. The response of CsI crystals to nuclear recoil was studied with mono-energetic...
Fracture Dynamics of Wedge-Loaded DCB Specimen. (2002)
Kobayashi,A. S., Mall,S., Lee,M. H.
Dynamic photoelasticity was used to analyze the Battelle-type wedge-loaded DCB specimen machined from Homalite-100 sheets of 3/8-inch (9.5mm) thickness. Dynamic stress intensity factors, dynamic...
Time and Frequency Dependent Behavior of a Two Dimensional Electron Gas at Long Wavelengths. (2002)
Using the recently developed method of recurrence relations, we have studied the time and frequency dependent behavior of the two dimensional electronic system at long wavelengths. Several families...
A general expression for the response function is derived by the method of recurrence relations. Memory effects appear as corrections to the dynamic RPA form. The dynamic structure for the 3d...
The static susceptibility of a free electron gas in D dimensions at T = O is obtained by techniques of dimensional regularization. Our solutions for the susceptibility chi(k,D) are given in terms of...
This document investigates the dynamics of the one-dimensional S=1/2 isotropic XY model and transverse Ising model in the high temperature limit by using the method of recurrence relations. The...
The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3 (2002)
Lee, M. H., Verma, V., Maskos, K., Becherer, J. D., Knäuper, V., Dodds, P., ...
Tumor necrosis factor-alpha converting enzyme (TACE) is an ADAM (a disintegrin and metalloproteinases) that comprises an active catalytic domain and several C-terminal domains. We compare the binding...
Lee, M. H., Verma, V., Maskos, K., Nath, D., Knäuper, V., Dodds, P., ...
We previously reported that full-length tissue inhibitor of metallo-proteinase-3 (TIMP-3) and its N-terminal domain form (N-TIMP-3) displayed equal binding affinity for tissue necrosis factor-alpha...
Lee, M. H., Maskos, K., Knäuper, V., Dodds, P., Murphy, G.
Tumor necrosis factor-alpha (TNF-alpha) converting enzyme (TACE/ADAM-17) is responsible for the release of TNF-u, a potent proinflammatory cytokine associated with many chronic debilitating diseases...
Einstein series and Poincaré for mixed automorphic forms (2000)
Mixed automorphic forms generalize elliptic modular forms, and they occur naturally as holomorphic forms of the highest degree on families of abelian varieties parametrized by a Riemann surface. We...
Dobson, C.C., Eskridge, R.H., Lee, M.H.
A four-channel laser transmissometer has been used to probe the soot content of the exhaust plume of the X-34 60k-lb thrust Fastrac rocket engine at NASA's Marshall Space Flight Center. The...
Test of CsI(Tl) crystals for the Dark Matter Search (1999)
Kim, H. J., Ahn, H. J., Kim, S. K., Won, E., Kim, T. Y., Kim, Y. D., ...
Searches for weakly interacting massive particles(WIMP) can be based on the dete ction of nuclear recoil energy in CsI(Tl) crystals. We demonstrate that low energy gamma rays down to few keV is...
Development of a new electrodeposition method for Pu-determination in environment samples. (1999)
Applied Radiation and Isotopes, 50(1999) S.851-58
Band Calculations on Ferroelectric and Piezoelectric Solids. (1998)
Henkel, J. H., Uzes, C. A., Lee, M. H.
The main objectives of the original proposal were to calculate spontaneous and other polarization properties of polar and piezoelectric crystals. The purpose of the work was to aid in selecting the...
Interdisciplinary Study in Physical Mathematics. (1998)
A study of nonlinear differential and integral equations which describe time-dependent phenomena in fluids and solids has been conducted by a team of investigators at the University of Georgia. The...
Analytical Theory of Continued Fractions and Time Evolution in Many-Particle Systems. (1998)
The analytical theory of continued fractions plays a key role in the time evolution behavior in many-particle systems. The aim of this study was to understand and to develop properties of relevant...
Generalized Jacobi forms and abelian schemes over arithmetic varieties (1998)
We generalize Jacobi forms of an arbitrary degree and construct torus bundles over abelian schemes whose sections can be identified with such generalized Jacobi forms.
Wong, M. L., Koh, D., Lee, M. H.
Workplace physical fitness programmes are usually poorly attended because the activities do not meet workers' needs. We investigated leisure-time physical activity and its relation to...
Compensation of Magnetic Impurity Effect in Superconductors by Radiation Damage (1997)
Park, Mi-Ae, Lee, M. H., Kim, Yong-Jihn
Compensation of the reduction of $T_{c}$ caused by magnetic impurities has been observed as a consequence of radiation damage. Using the recent theory by Kim and Overhauser (KO) we consider the...
Impurity scattering in a d-wave superconductor (1997)
Park, Mi-Ae, Lee, M. H., Kim, Yong-Jihn
The influence of (non-magnetic and magnetic) impurities on the transition temperature of a d-wave superconductor is studied anew within the framework of BCS theory. Pairing interaction decreases...
Study of the radiation hardness of CsI(Tl) crystals for the BELLE detector (1997)
Kazui, K, Watanabe, A, Osone, S, Cheon, B G, Fukushima, M, Hayashii, H, ...
Impurity Scattering In A D-Wave Superconductor (1997)
Mi-ae Park, M. H. Lee, Yong-jihn Kim
this paper is to reconsider the T c suppression due to (non-magnetic and magnetic) impurities in a d-wave superconductor within the framework of BCS theory. It is shown that the pairing interaction...
Measurement of $D^{\star + -}$ production in two-photon processes at TRISTAN (1996)
Takashimizu, N, Sasaki, T, Miyata, H, Aso, T, Miyano, K, Nakajima, N, ...
Ueno, K, Kanda, S, Olsen, S L, Kirk, P, Wang, T J, Abashian, Alexander, ...
Beam test of the CsI(Tl) calorimeter for the BELLE detector at the KEK-B factory (1996)
Ohshima, Y, Ahn, S H, Aoki, M, Awa, S, Fukushima, M, Hayashii, H, ...
Behari, S, Murakami, A, Kanda, S, Fujimoto, H, Kobayashi, S, Sahu, S K, ...
New limits on the masses of the selectron and photino (1996)
Sugimoto, Y, Abe, K, Fujii, Y, Igarashi, S, Kurihara, Y, Lee, M H, ...
Water Chemisorption and Reconstruction of the MgO Surface (1995)
Refson, K., Wogelius, R. A., Fraser, D. G., Payne, M. C., Lee, M. H., Milman, V.
The observed reactivity of MgO with water is in apparent conflict with theoretical calculations which show that molecular dissociation does not occur on a perfect (001) surface. We have performed...
A measurement of Bose-Einstein correlations in e+e- annihilation at TRISTAN (1995)
Choi, S K, Walker, R C, Bodek, Arie, Kim, B J, Velissaris, C, Kirk, P, ...
A high-Q$^{2}$ measurement of the photon structure function F$_{2}^{\gamma}$ (1995)
Sahu, S K, Ebara, S, Nozaki, T, Behari, S, Fujimoto, H, Kobayashi, S, ...
Modeling the impact of climate change on rice production in Asia. (1995)
Matthews, R.B., Kropff, M.J., Bachelet, D., Horie, T., Lee, M.H., Centeno, H.G.S., ...
Velissaris, C, Lusin, S, Chung, Y S, Park, K W, Cho, D K, Bodek, Arie, ...
Qualitative Modeling of Electrical Circuits (1992)
This paper presents a new model for the qualitative analysis of electrical circuit behaviour. We show that a qualitative representation of electrical resistance provides a good intuitive model of...
Recanalisation of Coronary Atherosclerotic Obstruction by Laser Radiation (1985)
Lee, G., Ikeda, R. M., Chan, M. C., Lee, M. H., Rink, J. L., Reis, R. L., ...
The potential use of lasers to vaporise atherosclerotic plaque obstructions is rapidly becoming recognised. The properties of laser light are unique in that it is coherent, monochromatic and...
The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons.
Lee, M H, Nikolic, M, Baptista, C A, Lai, E, Tsai, L H, Massagué, J
Cell cycle withdrawal in postmitotic cells involves cyclin-dependent kinase (Cdk) inhibitors that repress cell cycle Cdk activity. During mouse neurogenesis, cortical postmitotic neurons are shown...
Slebos, R J, Lee, M H, Plunkett, B S, Kessis, T D, Williams, B O, Jacks, T, ...
The cell cycle regulatory tumor suppressor proteins p53 and pRB are targeted for inactivation by several tumor viruses, including the high-risk types of human papillomaviruses (HPVs) via interactions...
Lee, M H, Pascopella, L, Jacobs, W R, Hatfull, G F
Mycobacteriophage L5, a temperate phage of mycobacteria, integrates site-specifically into the Mycobacterium smegmatis chromosome. We have identified the int gene and attP site of L5, characterized...
SOS mutagenesis in Escherichia coli requires the participation of a specialized system involving the activated form of UmuD (UmuD'), UmuC, RecA, and DNA polymerase III proteins. We have used a set of...
Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach.
Guzzo, A, Lee, M H, Oda, K, Walker, G C
On the basis of characterizations of a set of UmuD monocysteine derivatives, we had suggested that positions 24, 34, and 44 are closer to the intact UmuD homodimer interface than other positions...
Inhibition of RecA-mediated cleavage in covalent dimers of UmuD.
Lee, M H, Guzzo, A, Walker, G C
Disulfide-cross-linked UmuD2 derivatives were cleaved poorly upon incubation with activated RecA. Reducing the disulfide bonds prior to incubating the derivatives with RecA dramatically increased...
Pascopella, L, Collins, F M, Martin, J M, Lee, M H, Hatfull, G F, Stover, C K, ...
Novel molecular tools and genetic methods were developed to isolate genomic fragments of Mycobacterium tuberculosis that may be associated with virulence. We sought to restore virulence, a...
A monocysteine approach for probing the structure and interactions of the UmuD protein.
Lee, M H, Ohta, T, Walker, G C
UmuD participates in a variety of protein-protein interactions that appear to be essential for its role in UV mutagenesis. To learn about these interactions, we have initiated an approach based on...
Lee, M H, Mulrooney, S B, Renner, M J, Markowicz, Y, Hausinger, R P
The region located immediately upstream from the Klebsiella aerogenes urease structural genes was sequenced and shown to possess an open reading frame capable of encoding a 29.8-kDa peptide....
Mycobacteriophage L5 integrase-mediated site-specific integration in vitro.
Mycobacteriophage L5, a temperate phage of the mycobacteria, forms stable lysogens in Mycobacterium smegmatis via site-specific integration of the phage genome. Recombination occurs within specific...
Purification, characterization, and in vivo reconstitution of Klebsiella aerogenes urease apoenzyme.
Lee, M H, Mulrooney, S B, Hausinger, R P
Urease was purified from recombinant Klebsiella aerogenes which was grown in the absence of nickel. The protein was inactive and contained no transition metals, yet it possessed the same...
Urabe, T, Sano, K, Nakano, T, Odawara, F, Lee, M H, Otake, T, ...
We tested whether human immunodeficiency virus type 1 (HIV-1) could be differentiated from HIV-2 by a reverse transcriptase (RT)-typing assay that measured the reduction of enzyme activity owing to...
Backhouse, J L, Lee, M H, Nesteroff, S I, Hudson, B J, Hamilton, P A
A modified indirect hemagglutination test for the detection of treponemal antibodies was developed for use with finger-prick blood. By using paired serum and absorbed finger-prick blood from 58...
Lee, M H, Sano, K, Morales, F E, Imagawa, D T
The sensitive overnight reverse transcriptase and the antigen capture enzyme-linked immunosorbent assays were tested for their ability to detect human immunodeficiency virus. The two assays were able...
Advani, M, Imagawa, D T, Lee, M H, Sano, K, Morales, F, Mitsuyasu, R T, ...
A cross-sectional study of 128 individuals infected with human immunodeficiency virus type 1 (HIV-1) was conducted to determine the correlation of reverse transcriptase-inhibiting (RTI) antibody to...
Sensitive reverse transcriptase assay to detect and quantitate human immunodeficiency virus.
Lee, M H, Sano, K, Morales, F E, Imagawa, D T
A sensitive biochemical assay of viral reverse transcriptase (RT) was developed that is useful for both the detection and quantitation of human immunodeficiency virus (HIV), the agent responsible for...
Sano, K, Lee, M H, Morales, F, Nishanian, P, Fahey, J, Detels, R, ...
Most individuals infected with human immunodeficiency virus (HIV), the causative agent of acquired immune deficiency syndrome, produce an antibody against the viral reverse transcriptase (RT). Our...
Patel, S B, Salen, G, Hidaka, H, Kwiterovich, P O, Stalenhoef, A F, Miettinen, T A, ...
The molecular mechanisms regulating the amount of dietary cholesterol retained in the body as well as the body's ability to selectively exclude other dietary sterols are poorly understood. Studies of...
The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons.
Lee, M H, Nikolic, M, Baptista, C A, Lai, E, Tsai, L H, Massagué, J
Cell cycle withdrawal in postmitotic cells involves cyclin-dependent kinase (Cdk) inhibitors that repress cell cycle Cdk activity. During mouse neurogenesis, cortical postmitotic neurons are shown...
Slebos, R J, Lee, M H, Plunkett, B S, Kessis, T D, Williams, B O, Jacks, T, ...
The cell cycle regulatory tumor suppressor proteins p53 and pRB are targeted for inactivation by several tumor viruses, including the high-risk types of human papillomaviruses (HPVs) via interactions...
Lee, M H, Pascopella, L, Jacobs, W R, Hatfull, G F
Mycobacteriophage L5, a temperate phage of mycobacteria, integrates site-specifically into the Mycobacterium smegmatis chromosome. We have identified the int gene and attP site of L5, characterized...
SOS mutagenesis in Escherichia coli requires the participation of a specialized system involving the activated form of UmuD (UmuD'), UmuC, RecA, and DNA polymerase III proteins. We have used a set of...
Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach.
Guzzo, A, Lee, M H, Oda, K, Walker, G C
On the basis of characterizations of a set of UmuD monocysteine derivatives, we had suggested that positions 24, 34, and 44 are closer to the intact UmuD homodimer interface than other positions...
Inhibition of RecA-mediated cleavage in covalent dimers of UmuD.
Lee, M H, Guzzo, A, Walker, G C
Disulfide-cross-linked UmuD2 derivatives were cleaved poorly upon incubation with activated RecA. Reducing the disulfide bonds prior to incubating the derivatives with RecA dramatically increased...
Pascopella, L, Collins, F M, Martin, J M, Lee, M H, Hatfull, G F, Stover, C K, ...
Novel molecular tools and genetic methods were developed to isolate genomic fragments of Mycobacterium tuberculosis that may be associated with virulence. We sought to restore virulence, a...
A monocysteine approach for probing the structure and interactions of the UmuD protein.
Lee, M H, Ohta, T, Walker, G C
UmuD participates in a variety of protein-protein interactions that appear to be essential for its role in UV mutagenesis. To learn about these interactions, we have initiated an approach based on...
Lee, M H, Mulrooney, S B, Renner, M J, Markowicz, Y, Hausinger, R P
The region located immediately upstream from the Klebsiella aerogenes urease structural genes was sequenced and shown to possess an open reading frame capable of encoding a 29.8-kDa peptide....
Mycobacteriophage L5 integrase-mediated site-specific integration in vitro.
Mycobacteriophage L5, a temperate phage of the mycobacteria, forms stable lysogens in Mycobacterium smegmatis via site-specific integration of the phage genome. Recombination occurs within specific...
Purification, characterization, and in vivo reconstitution of Klebsiella aerogenes urease apoenzyme.
Lee, M H, Mulrooney, S B, Hausinger, R P
Urease was purified from recombinant Klebsiella aerogenes which was grown in the absence of nickel. The protein was inactive and contained no transition metals, yet it possessed the same...
Urabe, T, Sano, K, Nakano, T, Odawara, F, Lee, M H, Otake, T, ...
We tested whether human immunodeficiency virus type 1 (HIV-1) could be differentiated from HIV-2 by a reverse transcriptase (RT)-typing assay that measured the reduction of enzyme activity owing to...
Backhouse, J L, Lee, M H, Nesteroff, S I, Hudson, B J, Hamilton, P A
A modified indirect hemagglutination test for the detection of treponemal antibodies was developed for use with finger-prick blood. By using paired serum and absorbed finger-prick blood from 58...
Lee, M H, Sano, K, Morales, F E, Imagawa, D T
The sensitive overnight reverse transcriptase and the antigen capture enzyme-linked immunosorbent assays were tested for their ability to detect human immunodeficiency virus. The two assays were able...
Advani, M, Imagawa, D T, Lee, M H, Sano, K, Morales, F, Mitsuyasu, R T, ...
A cross-sectional study of 128 individuals infected with human immunodeficiency virus type 1 (HIV-1) was conducted to determine the correlation of reverse transcriptase-inhibiting (RTI) antibody to...
Sensitive reverse transcriptase assay to detect and quantitate human immunodeficiency virus.
Lee, M H, Sano, K, Morales, F E, Imagawa, D T
A sensitive biochemical assay of viral reverse transcriptase (RT) was developed that is useful for both the detection and quantitation of human immunodeficiency virus (HIV), the agent responsible for...
Sano, K, Lee, M H, Morales, F, Nishanian, P, Fahey, J, Detels, R, ...
Most individuals infected with human immunodeficiency virus (HIV), the causative agent of acquired immune deficiency syndrome, produce an antibody against the viral reverse transcriptase (RT). Our...
Patel, S B, Salen, G, Hidaka, H, Kwiterovich, P O, Stalenhoef, A F, Miettinen, T A, ...
The molecular mechanisms regulating the amount of dietary cholesterol retained in the body as well as the body's ability to selectively exclude other dietary sterols are poorly understood. Studies of...
Lee, M H, Chung, S W, Kang, B Y, Kim, K-M, Kim, T S
Exposure to cigarette smoke is known to increase the risk of the development of allergic disease. The mechanism is not well understood. In this study, we determined the effect of hydroquinone (HQ), a...
Kim, T S, Kang, B Y, Lee, M H, Choe, Y K, Hwang, S Y
Interleukin-12 (IL-12) may play a central role in the development and progression of rheumatoid arthritis by driving the immune response towards T helper 1 (Th1) type responses characterized by high...
Kang, S N, Kim, S H, Chung, S W, Lee, M H, Kim, H J, Kim, T S
Transcription factors such as NF-κB provide powerful targets for drugs to use in the treatment of cancer. In this report parthenolide (PT), a sesquiterpene lactone of herbal remedies such as...
Lee, M. H., Pankratz, H. S., Wang, S., Scott, R. A., Finnegan, M. G., Johnson, M. K., ...
The Klebsiella aerogenes ureE gene product was previously shown to facilitate assembly of the urease metallocenter (Lee, M.H., et al., 1992, J. Bacteriol. 174, 4324-4330). UreE protein has now been...
Clà ria, J., Lee, M. H., Serhan, C. N.
BACKGROUND: The mechanism by which aspirin (ASA) acts to protect against human cancer is not yet known. We recently showed that ASA triggers the formation of a new series of potent bioactive...
N. Takashimizu, T. Sasaki, H. Miyata, T. Aso, K. Miyano, N. Nakajima, ...
production in two-photon processes