Okada, H, 岡田, 浩美, Yamazaki, T, Takagi, A, Murate, T, Yamamoto, K, ...
岡田 浩美… 名古屋大学博士学位論文 学位の種類:博士（医療技術学）（課程）甲7291号 学位授与年月日:平成19年3月23日 "In vitro characterization of missense...
Ganglioside GM1 binds to the Trk protein and regulates receptor function.
Mutoh, T, Tokuda, A, Miyadai, T, Hamaguchi, M, Fujiki, N
Several lines of evidence have suggested that ganglioside GM1 stimulates neuronal sprouting and enhances the action of nerve growth factor (NGF), but its precise mechanism is yet to be elucidated. We...
Establishment of a highly sensitive and specific exon-trapping system.
Hamaguchi, M, Sakamoto, H, Tsuruta, H, Sasaki, H, Muto, T, Sugimura, T, ...
We have established a highly sensitive and specific exon-trapping system (SETS) with a specific plasmid vector in which an exon in a given DNA segment is identified by its ability to remain as a...
Taga, T, Narazaki, M, Yasukawa, K, Saito, T, Miki, D, Hamaguchi, M, ...
Functional pleiotropy and redundancy are characteristic features of cytokines. To understand the signaling mechanisms of such cytokines, we have proposed a two-chain interleukin (IL) 6 receptor...
Murakami, M, Narazaki, M, Hibi, M, Yawata, H, Yasukawa, K, Hamaguchi, M, ...
Interleukin 6 (IL-6) signal is transduced through gp130 that associates with a complex of IL-6 and IL-6 receptor. Truncations or amino acid substitutions offe introduced in the cytoplasmic region of...
Dutta, A, Hamaguchi, M, Hanafusa, H
We found that transcription from the promoter in the long terminal repeat of Rous sarcoma virus in rat 3Y1 cells is dependent on the presence of serum in the culture. However, this serum dependence...
Assignment of disulfide bridges in the fusion glycoprotein of Sendai virus.
Iwata, S, Schmidt, A C, Titani, K, Suzuki, M, Kido, H, Gotoh, B, ...
The mature fusion (F) glycoprotein of the paramyxovirus family consists of two disulfide-linked subunits, the N-terminal F2 and the C-terminal F1 subunits, and contains 10 cysteine residues which are...
Ohnishi, Y, Shioda, T, Nakayama, K, Iwata, S, Gotoh, B, Hamaguchi, M, ...
Furin, a subtilisin-like mammalian endoprotease, is thought to be responsible for the processing of many proprotein precursors of cellular and viral origin, including gp160 of human immunodeficiency...
Shiroki, K, Hamaguchi, M, Kawai, S
When rat 3Y1 cells were infected with Rous sarcoma virus (RSV) variant SR-RSV-D(H), many 3Y1 cells acquired a stable provirus but only few of them formed transformed foci. In contrast, 12E1AY cells...
More than 70% of wild-type Rous sarcoma virus p60v-src was found to be associated with a cellular structure resistant to nonionic detergent extraction that consists primarily of cytoskeletal...
A glycoprotein in the plasma membrane matrix as a major potential substrate of p60v-src.
Hamaguchi, M, Matsuda, M, Hanafusa, H
A potential substrate of p60v-src in Rous sarcoma virus-transformed cells was found to be a 130-kilodalton (kDa) glycoprotein which binds to lectin-Sepharose and can be immunoprecipitated by an...
Hamaguchi, M, Grandori, C, Hanafusa, H
The protein substrates for the tyrosine protein kinases in cells transformed by avian sarcoma viruses were analyzed by gel electrophoresis in combination with immunoblotting or immunoprecipitation by...
Hamaguchi, M, Matsuyoshi, N, Ohnishi, Y, Gotoh, B, Takeichi, M, Nagai, Y
Transformation of chick embryonic fibroblasts with Rous sarcoma virus strongly suppresses N-cadherin-mediated cell-cell adhesion, without inhibiting its expression. This suppression is correlated...
Gotoh, B, Ogasawara, T, Toyoda, T, Inocencio, N M, Hamaguchi, M, Nagai, Y
Host cell proteases responsible for activation of viral fusion glycoproteins are an important determinant for spread and tropism of various animal viruses. Exemplifying such proteases for the first...
Ganglioside GM1 binds to the Trk protein and regulates receptor function.
Mutoh, T, Tokuda, A, Miyadai, T, Hamaguchi, M, Fujiki, N
Several lines of evidence have suggested that ganglioside GM1 stimulates neuronal sprouting and enhances the action of nerve growth factor (NGF), but its precise mechanism is yet to be elucidated. We...
Establishment of a highly sensitive and specific exon-trapping system.
Hamaguchi, M, Sakamoto, H, Tsuruta, H, Sasaki, H, Muto, T, Sugimura, T, ...
We have established a highly sensitive and specific exon-trapping system (SETS) with a specific plasmid vector in which an exon in a given DNA segment is identified by its ability to remain as a...
Taga, T, Narazaki, M, Yasukawa, K, Saito, T, Miki, D, Hamaguchi, M, ...
Functional pleiotropy and redundancy are characteristic features of cytokines. To understand the signaling mechanisms of such cytokines, we have proposed a two-chain interleukin (IL) 6 receptor...
Murakami, M, Narazaki, M, Hibi, M, Yawata, H, Yasukawa, K, Hamaguchi, M, ...
Interleukin 6 (IL-6) signal is transduced through gp130 that associates with a complex of IL-6 and IL-6 receptor. Truncations or amino acid substitutions offe introduced in the cytoplasmic region of...
Dutta, A, Hamaguchi, M, Hanafusa, H
We found that transcription from the promoter in the long terminal repeat of Rous sarcoma virus in rat 3Y1 cells is dependent on the presence of serum in the culture. However, this serum dependence...
Assignment of disulfide bridges in the fusion glycoprotein of Sendai virus.
Iwata, S, Schmidt, A C, Titani, K, Suzuki, M, Kido, H, Gotoh, B, ...
The mature fusion (F) glycoprotein of the paramyxovirus family consists of two disulfide-linked subunits, the N-terminal F2 and the C-terminal F1 subunits, and contains 10 cysteine residues which are...
Ohnishi, Y, Shioda, T, Nakayama, K, Iwata, S, Gotoh, B, Hamaguchi, M, ...
Furin, a subtilisin-like mammalian endoprotease, is thought to be responsible for the processing of many proprotein precursors of cellular and viral origin, including gp160 of human immunodeficiency...
Shiroki, K, Hamaguchi, M, Kawai, S
When rat 3Y1 cells were infected with Rous sarcoma virus (RSV) variant SR-RSV-D(H), many 3Y1 cells acquired a stable provirus but only few of them formed transformed foci. In contrast, 12E1AY cells...
More than 70% of wild-type Rous sarcoma virus p60v-src was found to be associated with a cellular structure resistant to nonionic detergent extraction that consists primarily of cytoskeletal...
A glycoprotein in the plasma membrane matrix as a major potential substrate of p60v-src.
Hamaguchi, M, Matsuda, M, Hanafusa, H
A potential substrate of p60v-src in Rous sarcoma virus-transformed cells was found to be a 130-kilodalton (kDa) glycoprotein which binds to lectin-Sepharose and can be immunoprecipitated by an...
Hamaguchi, M, Grandori, C, Hanafusa, H
The protein substrates for the tyrosine protein kinases in cells transformed by avian sarcoma viruses were analyzed by gel electrophoresis in combination with immunoblotting or immunoprecipitation by...
Hamaguchi, M, Matsuyoshi, N, Ohnishi, Y, Gotoh, B, Takeichi, M, Nagai, Y
Transformation of chick embryonic fibroblasts with Rous sarcoma virus strongly suppresses N-cadherin-mediated cell-cell adhesion, without inhibiting its expression. This suppression is correlated...
Gotoh, B, Ogasawara, T, Toyoda, T, Inocencio, N M, Hamaguchi, M, Nagai, Y
Host cell proteases responsible for activation of viral fusion glycoproteins are an important determinant for spread and tropism of various animal viruses. Exemplifying such proteases for the first...
Zhang, Y H, Isobe, K, Nagase, F, Lwin, T, Kato, M, Hamaguchi, M, ...
Cellular and molecular mechanisms of the immunomodulatory action of glycyrrhizin (GL) were studied. We demonstrated that GL displays a unique action to prolong the duration of the T-cell...
Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis
Hayakawa, T, Fujiwara, Y, Hamaguchi, M, Sugawa, T, Okuyama, M, Sasaki, E, ...
Tyrosine phosphorylation of 100-130 kDa proteins in lung cancer correlates with poor prognosis.
Nishimura, M., Machida, K., Imaizumi, M., Abe, T., Umeda, T., Takeshima, E., ...
To search for the signalling pathways in lung cancer relevant to its aggressive behaviour, we studied tyrosine phosphorylated proteins in lung cancer cell lines and surgical specimens. We found that...