Suzuki, T., Hasegawa, M., Ishiguro, K., Koma, Y., Sekido, T.
The mechanism of non-Abelian color confinement is studied in SU(2) lattice gauge theory in terms of the Abelian fields and monopoles extracted from non-Abelian link variables without adopting gauge...
A Methodology of Persona-centric Service Design (2009)
Hosono, S., Hasegawa, M., Hara, T., Shimomura, Y., Arai, T.
Organised by: Cranfield University
Shell model study of single-particle and collective structure in neutron-rich Cr isotopes (2008)
Kaneko, K., Sun, Y., Hasegawa, M., Mizusaki, T.
The structure of neutron-rich Cr isotopes is systematically investigated by using the spherical shell model. The calculations reproduce well the known energy levels for the even-even $^{52-62}$Cr and...
Solar neutrino measurements in Super-Kamiokande-II (2008)
Cravens, J. P., Abe, K., Iida, T., Ishihara, K., Kameda, J., Koshio, Y., ...
The results of the second phase of the Super-Kamiokande solar neutrino measurement are presented and compared to the first phase. The solar neutrino flux spectrum and time variation as well as...
Field-induced quantum critical route to a Fermi liquid in high-temperature superconductors (2008)
Shibauchi, T., Krusin-Elbaum, L., Hasegawa, M., Kasahara, Y., Okazaki, R., Matsuda, Y.
In high transition temperature (T_c) superconductivity, charge doping is a natural tuning parameter that takes copper oxides from the antiferromagnet to the superconducting region. In the metallic...
Structure of upper g9/2-shell nuclei and shape effect in the 94Ag isomeric states (2008)
Kaneko, K., Sun, Y., Hasegawa, M., Mizusaki, T.
Using a shell model which is capable of describing the spectra of upper $g_{9/2}$-shell nuclei close to the $N=Z$ line, we study the structure of two isomeric states $7^{+}$ and $21^{+}$ in the...
COHERENCE OF THE DOUBLE INVOLUTION ON \Lambda-AUTONOMOUS CATEGORIES (2008)
Fortunately, there is no such semantic gap: in this paper we provide a coherence theorem for the double involution on \Lambda-autonomous categories, which tells us that there is no difference between...
A Chemical Distance Based Test for Positive Darwinian Selection (2007)
T. Pupko, R. Sharan, M. Hasegawa, R. Shamir
Abstract. There are very few instances in which positive Darwinian selection has been convincingly demonstrated at the molecular level. In this study, we present a novel test for detecting positive...
Coherence Of The Double Involution On (2007)
Autonomous Categories Cockett, M. Hasegawa
We show that any free -autonomous category is equivalent (in a strict sense) to a free -autonomous category in which the double-involution (\Gamma) is the identity functor and the canonical...
Toyoma, T., Nagai, Y., Tang, Z., Hasegawa, M., Al Mazouzi, Abderrahim, Van Walle, Eric, ...
The nanostructural evolution of irradiation-induced Cu-rich nano precipitates (CRNPs) and vacancy clusters in surveillance test specimens of the in-service commercial nuclear reactor pressure vessel...
Iwata, Y., Ogawa, F., Komura, K., Muroi, E., Hara, T., Shimizu, K., ...
Objectives. To determine the prevalence and clinical correlation of autoantibody to peroxiredoxin (Prx) I, an antioxidant enzyme, in patients with systemic sclerosis (SSc). Methods. Serum samples...
Guillian, G., Hosaka, J., Ishihara, K., Kameda, J., Koshio, Y., Minamino, A., ...
The relative sidereal variation in the arrival direction of primary cosmic ray nuclei of median energy 10 TeV was measured using downward, through-going muons detected with the Super-Kamiokande-I...
Enhancement of $B(E2)$ and low excitation of the second 0$^+$ state near N=40 in Ge isotopes (2007)
Hasegawa, M., Mizusaki, T., Kaneko, K., Sun, Y.
The long-standing problem of dramatic structure change near N=40 in Ge isotopes is investigated by means of large-scale shell model calculation. The analysis of simulated calculations suggests a...
Isobe, K, Kagami, Y, Higuchi, K, Kodaira, T, Hasegawa, M, Shikama, N, ...
This is a pre-copy-editing, author-produced PDF of an article accepted for publication in [JAPANESE JOURNAL OF CLINICAL ONCOLOGY] following peer review. The definitive publisher-authenticated version...
Sendai virus-mediated CFTR gene transfer to the airway epithelium (2007)
Ferrari, S., Griesenbach, U., Iida, A., Farley, R., Wright, A. M., Zhu, J., ...
The potential for gene therapy to be an effective treatment for cystic fibrosis has been hampered by the limited gene transfer efficiency of current vectors. We have shown that recombinant Sendai...
Sendai virus-mediated CFTR gene transfer to the airway epithelium (2007)
Ferrari, S., Griesenbach, U., Iida, A., Farley, R., Wright, A. M., Zhu, J., ...
The potential for gene therapy to be an effective treatment for cystic fibrosis has been hampered by the limited gene transfer efficiency of current vectors. We have shown that recombinant Sendai...
Iwata, Y., Ogawa, F., Komura, K., Muroi, E., Hara, T., Shimizu, K., ...
Objectives. To determine the prevalence and clinical correlation of autoantibody to peroxiredoxin (Prx) I, an antioxidant enzyme, in patients with systemic sclerosis (SSc). Methods. Serum samples...
Kaji, K., Fujimoto, M., Hasegawa, M., Kondo, M., Saito, Y., Komura, K., ...
Objective. Myositis-specific autoantibodies (MSAs) are a useful tool in diagnosis, defining clinical subsets and predicting prognosis of dermatomyositis (DM) and polymyositis (PM). In this study, we...
Iwata, Y., Ogawa, F., Komura, K., Muroi, E., Hara, T., Shimizu, K., ...
Objectives. To determine the prevalence and clinical correlation of autoantibody to peroxiredoxin (Prx) I, an antioxidant enzyme, in patients with systemic sclerosis (SSc). Methods. Serum samples...
Phase transition in exotic nuclei along the $N=Z$ line (2006)
Hasegawa, M., Kaneko, K., Mizusaki, T., Sun, Y.
The abrupt structure change from the nuclei of $N=Z \le 35$ to those of $N=Z \ge 36$ is investigated by means of shell model calculations. The basic features of the even-even and odd-odd nuclei under...
Ohdachi, S., Hasegawa, M., Iwasa, M., Vogel, P., Oshida, T., ...
Molecular phylogeny of soricid shrews (Soricidae, Eulipotyphla, Mammalia) based on 1140 bp mitochondrial cytochrome b gene (cytb) sequences was inferred by the maximum likelihood (ML) method. All 13...
Ohdachi, S., Hasegawa, M., Iwasa, M., Vogel, P., Oshida, T., ...
Molecular phylogeny of soricid shrews (Soricidae, Eulipotyphla, Mammalia) based on 1140 bp mitochondrial cytochrome b gene (cytb) sequences was inferred by the maximum likelihood (ML) method. All 13...
Ohdachi, S., Hasegawa, M., Iwasa, M., Vogel, P., Oshida, T., ...
Molecular phylogeny of soricid shrews (Soricidae, Eulipotyphla, Mammalia) based on 1140 bp mitochondrial cytochrome b gene (cytb) sequences was inferred by the maximum likelihood (ML) method. All 13...
Breaking of nucleon Cooper pairs at finite temperature in 93-98Mo (2006)
Kaneko, K., Hasegawa, M., Agvaanluvsan, U., Algin, E., Chankova, R., Guttormsen, M., ...
The S shape of the canonical heat capacity is known as a signature of the pairing transition and along an isotopic chain it is significantly more pronounced for nuclei with an even number of neutrons...
Magicity and occurrence of band with enhanced B(E2) in neutron-rich nuclei 68Ni and 90Zr (2006)
Kaneko, K., Hasegawa, M., Mizusaki, T., Sun, Y.
Experimental energy spectrum and B(E2) values in 68Ni and 90Zr indicate a double-magic character in these neutron-rich nuclei with N or Z=40. The data nevertheless do not show any pronounced...
Deuteron and Anti-deuteron Production in $e^+ e^-$ Collisions at the Z Resonance (2006)
Schael, S, Aubert, B, Zalipska, J, Yoshida, M, Yoo, J, Yokoyama, M, ...
Deuteron and anti-deuteron production in Z decays has been observed in the ALEPH experiment at LEP. The production rate of anti-deuterons is measured to be 5.9+-1.8+-0.5 10^-6 per hadronic Z decay in...
Molecular Mechanism of Fas ligand-induced IL-8 Production (2006)
Imamura, R., Matsumoto, N., Hasegawa, M., Konaka, K., Suda, T.
PYNOD, a Novel Apaf-1/CED4-like Protein is an Inhibitor of ASC and Caspase-1 (2006)
Wang, Y., Hasegawa, M., Imamura, R., Kinoshita, T., Kondo, C., Konaka, K., ...
Voronoi analysis of the structure of Cu-Zr and Ni-Zr metallic glasses (2006)
Fukunaga, T, Itoh, K, Otomo, T, Mori, K, Sugiyama, M, Kato, H, ...
Phylogenetic analysis of diprotodontian marsupials based on complete mitochondrial genomes (2006)
Munemasa, M., Nikaido, M., Donnellan, S., Austin, C. C., Okada, N., Hasegawa, M.
Phylogenetic analysis of diprotodontian marsupials based on complete mitochondrial genomes (2006)
Munemasa, M., Nikaido, M., Donnellan, S., Austin, C. C., Okada, N., Hasegawa, M.
Voronoi analysis of the structure of Cu-Zr and Ni-Zr metallic glasses (2006)
Fukunaga, T, Itoh, K, Otomo, T, Mori, K, Sugiyama, M, Kato, H, ...
Topological characterization of metallic glasses by neutron diffraction and RMC modeling (2006)
Fukunaga, T, Itoh, K, Otomo, T, Mori, K, Sugiyama, M, Kato, H, ...
Ogawa, F., Shimizu, K., Muroi, E., Hara, T., Hasegawa, M., Takehara, K., ...
Objective. To determine serum levels and clinical correlation of 8-isoprostane, which is produced in vivo through free radical-catalysed peroxidation of arachidonic acid and reflects oxidative...
Ogawa, F., Shimizu, K., Muroi, E., Hara, T., Hasegawa, M., Takehara, K., ...
Objective. To determine serum levels and clinical correlation of 8-isoprostane, which is produced in vivo through free radical-catalysed peroxidation of arachidonic acid and reflects oxidative...
Kaji, K., Fujimoto, M., Hasegawa, M., Kondo, M., Saito, Y., Komura, K., ...
Objective. Myositis-specific autoantibodies (MSAs) are a useful tool in diagnosis, defining clinical subsets and predicting prognosis of dermatomyositis (DM) and polymyositis (PM). In this study, we...
Ogawa, F., Shimizu, K., Muroi, E., Hara, T., Hasegawa, M., Takehara, K., ...
Objective. To determine serum levels and clinical correlation of 8-isoprostane, which is produced in vivo through free radical-catalysed peroxidation of arachidonic acid and reflects oxidative...
Kaji, K., Fujimoto, M., Hasegawa, M., Kondo, M., Saito, Y., Komura, K., ...
Objective. Myositis-specific autoantibodies (MSAs) are a useful tool in diagnosis, defining clinical subsets and predicting prognosis of dermatomyositis (DM) and polymyositis (PM). In this study, we...
Kumagai, K., Kakuyanagi, K., Saitoh, M., Matsuda, Y., Hasegawa, M., Takashima, S., ...
Spatially-resolved NMR is used to probe internal structures in highly correlated superconductors of optimally-doped Tl2Ba2CuO(6+δ)(Tc=85K) and a heavy fermion superconductor CeCoIn5 (Tc=2.3K). The...
Kumagai, K., Kakuyanagi, K., Saitoh, M., Matsuda, Y., Hasegawa, M., Takashima, S., ...
Spatially-resolved NMR is used to probe internal structures in highly correlated superconductors of optimally-doped Tl2Ba2CuO(6+δ)(Tc=85K) and a heavy fermion superconductor CeCoIn5 (Tc=2.3K). The...
Kumagai, K., Kakuyanagi, K., Saitoh, M., Matsuda, Y., Hasegawa, M., Takashima, S., ...
Spatially-resolved NMR is used to probe internal structures in highly correlated superconductors of optimally-doped Tl2Ba2CuO(6+δ)(Tc=85K) and a heavy fermion superconductor CeCoIn5 (Tc=2.3K). The...
Contour integral method for thermal and quantal fluctuations (2005)
The partition function by means of the static path approximation (SPA) plus the random-phase approximation (RPA) treatment can be written as a contour integral form without solving the RPA equations...
Unique features of structure in an odd-proton $N \approx Z$ nucleus $^{69}$As (2005)
Hasegawa, M., Kaneko, K., Mizusaki, T.
We apply a large-scale shell model to the study of proton-rich odd-mass nuclei with $N \approx Z$. Calculations predict unexpected structure in the $^{69}$As nucleus for which a detailed experiment...
Proton-neutron pairing energies in N=Z nuclei at finite temperature (2005)
Thermal behavior of isoscalar and isovector proton-neutron (pn) pairing energies at finite temperature are investigated by the shell model calculations. These pn pairing energies can be estimated by...
Quenching of pairing gap at finite temperature in 184W (2005)
We extract pairing gap in $^{184}$W at finite temperature for the first time from the experimental level densities of $^{183}$W, $^{184}$W, and $^{185}$W using "thermal" odd-even mass difference. We...
Structure of isomeric states in 66As and 67As (2005)
Hasegawa, M., Sun, Y., Kaneko, K., Mizusaki, T.
Strong residual correlations between neutrons and protons in N ~ Z systems can lead to unusual structure. Using the spherical shell model, we show that a low-excitation shape isomer can occur in the...
An alternative understanding of mass formulas in terms of nuclear structure (2005)
A typical form of mass formula is re-explained in terms of nuclear structure. For $ N \approx Z $ nuclei, we propose to start with the shell model picture and to consider the T=0 $2n-2p$...
Self-energy correction to momentum-density distribution of positron-electron pairs (2005)
Tang, Z., Nagai, Y., Inoue, K., Toyama, T., Chiba, T., Saito, Mineo, ...
Positron two-dimensional angular correlation of annihilation radiation (2D ACAR), i.e., the 2D projection of the electron momentum densities sampled by positron, in Si is employed to verify the...
Anomalous behavior of the first excited 0$^{+}$ state in $N \approx Z$ nuclei (2005)
Kaneko, K., Casten, R. F., Hasegawa, M., Mizusaki, T., Zhang, Jing-ye, McCutchan, E. A., ...
A study of the energies of the first excited $0^+$ states in all even-even $Z$ $\geq$ 8 nuclei reveals an anomalous behavior in some nuclei with $N$ = $Z$, $Z$ $\pm$ 2. We analyze these...
Zushi, H, Nakamura, K, Hanada, K, Sato, KN, Sakamoto, M, Idei, H, ...
Takeuchi, T, Nakano, S, Hasegawa, M, Soda, K, Sato, H, Mizutani, U, ...
Coherence Of The Double Involution On (2005)
Autonomous Categories Cockett, M. Hasegawa
We show that any free category is strictly equivalent to a free category in which the double-involution (-) ## is the identity functor and the canonical isomorphism A A ## is an identity arrow for...
Ichiyama, T., Ueno, Y., Hasegawa, M., Ishikawa, Y., Matsubara, T., Furukawa, S.
Objectives. Intravenous immunoglobulin (IVIG) therapy has been reported to be effective for reducing the incidence of coronary artery lesions in Kawasaki disease (KD), an acute febrile vasculitis of...
Hayakawa, I., Hasegawa, M., Matsushita, T., Yanaba, K., Kodera, M., Komura, K., ...
Objective. We sought to assess serum cutaneous T-cell-attracting chemokine (CTACK) levels and CTACK expression levels in skin from patients with systemic sclerosis (SSc), and determine whether serum...
Hayakawa, I., Hasegawa, M., Matsushita, T., Yanaba, K., Kodera, M., Komura, K., ...
Objective. We sought to assess serum cutaneous T-cell-attracting chemokine (CTACK) levels and CTACK expression levels in skin from patients with systemic sclerosis (SSc), and determine whether serum...
Microscopic analysis of T=1 and T=0 proton-neutron correlations in $N=Z$ nuclei (2004)
The competition between the isovector (T=1) and isoscalar (T=0) proton-neutron ($p-n$) correlations in $N=Z$ nuclei is investigated by calculating their correlation energies with a realistic...
Hasegawa, M., Fujimoto, M., Hayakawa, I., Matsushita, T., Nishijima, C., Yamazaki, M., ...
Objective: To determine the frequency and clinical association of antiphosphatidylserine-prothrombin complex (PS/PT) antibody (Ab) in systemic sclerosis (SSc). Methods: Anti-PS/PT IgG Ab was examined...
Estimation of Power Balance in Steady State LHCD Discharges on TRIAM-1M (2004)
Sugata, Tomoya, Hanada, K., Imamura, N., Sakamoto, M., Zushi, H., Idei, H., ...
On TRIAM-1M, a long duration discharge for more than 5 h was achieved successfully by fully non-inductive lower hybrid current drive. Heat load distribution to the plasma facing components (PFCs) in...
Estimation of Power Balance in Steady State LHCD Discharges on TRIAM-1M (2004)
Sugata, Tomoya, Hanada, K., Imamura, N., Sakamoto, M., Zushi, H., Idei, H., ...
On TRIAM-1M, a long duration discharge for more than 5 h was achieved successfully by fully non-inductive lower hybrid current drive. Heat load distribution to the plasma facing components (PFCs) in...
Ion acceleration during internal magnetic reconnection events in TST-2 (2004)
Hoshika, Hiroyuki, Zushi, H., Aramasu, M., Idei, H., Iyomasa, A., Ejiri, A., ...
Characteristics of ion acceleration in the internal magnetic reconnection events (IRE) have been studied by means of a neutral particle energy analyzer (NPA) in Tokyo Spherical Tokamak (TST-2). The...
Estimation of Power Balance in Steady State LHCD Discharges on TRIAM-1M (2004)
Sugata, Tomoya, Hanada, K., Imamura, N., Sakamoto, M., Zushi, H., Idei, H., ...
On TRIAM-1M, a long duration discharge for more than 5 h was achieved successfully by fully non-inductive lower hybrid current drive. Heat load distribution to the plasma facing components (PFCs) in...
Transport barrier formation by LHCD on TRIAM-1M (2004)
Hanada, K., Iyomasa, A., Zushi, H., Hasegawa, M., Sasaki, K., Hoshika, H., ...
Internal transport barrier (ITB) has been obtained in full lower hybrid current driven (LHCD) plasmas on a superconducting tokamak, TRIMA-1M (R=0.84m, a x b=0.12mx0.18m, BT
Shape transition and oblate-prolate coexistence in N=Z fpg-shell nuclei (2004)
Kaneko, K., Hasegawa, M., Mizusaki, T.
Nuclear shape transition and oblate-prolate coexistence in $N=Z$ nuclei are investigated within the configuration space ($2p_{3/2}$, $1f_{5/2}$, $2p_{1/2}$, and $1g_{9/2}$). We perform shell model...
Proton-neutron alignment in the yrast states of $^{66}$Ge and $^{68}$Ge (2004)
Hasegawa, M., Kaneko, K., Mizusaki, T.
The $^{66}$Ge and $^{68}$Ge nuclei are studied by means of the shell model with the extended $P+QQ$ Hamiltonian, which succeeds in reproducing experimentally observed energy levels, moments of...
Particle alignments and shape change in $^{66}$Ge and $^{68}$Ge (2004)
Hasegawa, M., Kaneko, K., Mizusaki, T.
The structure of the $N \approx Z$ nuclei $^{66}$Ge and $^{68}$Ge is studied by the shell model on a spherical basis. The calculations with an extended $P+QQ$ Hamiltonian in the configuration space...
Ashie, Y, Fukuda, S, Fukuda, Y, Ishihara, K, Itow, Y, ...
A search for a nonzero neutrino magnetic moment has been conducted using 1496 live days of solar neutrino data from Super-Kamiokande-I. Specifically, we searched for distortions to the energy...
Ion acceleration during internal magnetic reconnection events in TST-2 (2004)
Hoshika, Hiroyuki, Zushi, H., Aramasu, M., Idei, H., Iyomasa, A., Ejiri, A., ...
Characteristics of ion acceleration in the internal magnetic reconnection events (IRE) have been studied by means of a neutral particle energy analyzer (NPA) in Tokyo Spherical Tokamak (TST-2). The...
Transport barrier formation by LHCD on TRIAM-1M (2004)
Hanada, K., Iyomasa, A., Zushi, H., Hasegawa, M., Sasaki, K., Hoshika, H., ...
Internal transport barrier (ITB) has been obtained in full lower hybrid current driven (LHCD) plasmas on a superconducting tokamak, TRIMA-1M (R=0.84m, a x b=0.12mx0.18m, BT<8T). The formation of...
Ion acceleration during internal magnetic reconnection events in TST-2 (2004)
Hoshika, Hiroyuki, Zushi, H., Aramasu, M., Idei, H., Iyomasa, A., Ejiri, A., ...
Characteristics of ion acceleration in the internal magnetic reconnection events (IRE) have been studied by means of a neutral particle energy analyzer (NPA) in Tokyo Spherical Tokamak (TST-2). The...
Transport barrier formation by LHCD on TRIAM-1M (2004)
Hanada, K., Iyomasa, A., Zushi, H., Hasegawa, M., Sasaki, K., Hoshika, H., ...
Internal transport barrier (ITB) has been obtained in full lower hybrid current driven (LHCD) plasmas on a superconducting tokamak, TRIMA-1M (R=0.84m, a x b=0.12mx0.18m, BT<8T). The formation of...
Pairing transition of nuclei at finite temperature (2004)
Pairing transition at finite temperature was investigated by the shell model and BCS calculations. The definitive signature of pairing transition is identified by a "transition temperature" $T_t$...
Estimation of Power Balance in Steady State LHCD Discharges on TRIAM-1M (2004)
Sugata, Tomoya, Hanada, K., Imamura, N., Sakamoto, M., Zushi, H., Idei, H., ...
On TRIAM-1M, a long duration discharge for more than 5 h was achieved successfully by fully non-inductive lower hybrid current drive. Heat load distribution to the plasma facing components (PFCs) in...
Ion acceleration during internal magnetic reconnection events in TST-2 (2004)
Hoshika, Hiroyuki, Zushi, H., Aramasu, M., Idei, H., Iyomasa, A., Ejiri, A., ...
Characteristics of ion acceleration in the internal magnetic reconnection events (IRE) have been studied by means of a neutral particle energy analyzer (NPA) in Tokyo Spherical Tokamak (TST-2). The...
Transport barrier formation by LHCD on TRIAM-1M (2004)
Hanada, K., Iyomasa, A., Zushi, H., Hasegawa, M., Sasaki, K., Hoshika, H., ...
Internal transport barrier (ITB) has been obtained in full lower hybrid current driven (LHCD) plasmas on a superconducting tokamak, TRIMA-1M (R=0.84m, a x b=0.12mx0.18m, BT<8T). The formation of...
Estimation of Power Balance in Steady State LHCD Discharges on TRIAM-1M (2004)
Sugata, Tomoya, Hanada, K., Imamura, N., Sakamoto, M., Zushi, H., Idei, H., ...
On TRIAM-1M, a long duration discharge for more than 5 h was achieved successfully by fully non-inductive lower hybrid current drive. Heat load distribution to the plasma facing components (PFCs) in...
Ion acceleration during internal magnetic reconnection events in TST-2 (2004)
Hoshika, Hiroyuki, Zushi, H., Aramasu, M., Idei, H., Iyomasa, A., Ejiri, A., ...
Characteristics of ion acceleration in the internal magnetic reconnection events (IRE) have been studied by means of a neutral particle energy analyzer (NPA) in Tokyo Spherical Tokamak (TST-2). The...
Transport barrier formation by LHCD on TRIAM-1M (2004)
Hanada, K., Iyomasa, A., Zushi, H., Hasegawa, M., Sasaki, K., Hoshika, H., ...
Internal transport barrier (ITB) has been obtained in full lower hybrid current driven (LHCD) plasmas on a superconducting tokamak, TRIMA-1M (R=0.84m, a x b=0.12mx0.18m, BT<8T). The formation of...
Pickering-Brown, S. M., Baker, M., Nonaka, T., Ikeda, K., Sharma, S., Mackenzie, J., ...
In this report, we describe the clinical and neuropathological features of a case of familial frontotemporal dementia (FTD), with onset at 58 years of age and disease duration of 10 years, associated...
Serum soluble CTLA-4 levels are increased in diffuse cutaneous systemic sclerosis (2004)
Sato, S., Fujimoto, M., Hasegawa, M., Komura, K., Yanaba, K., Hayakawa, I., ...
Objective. To determine serum levels of soluble cytotoxic T-lymphocyte associated molecule-4 (sCTLA-4) and clinical association in patients with systemic sclerosis (SSc). Methods. Serum sCTLA-4...
Ichiyama, T., Ueno, Y., Hasegawa, M., Ishikawa, Y., Matsubara, T., Furukawa, S.
Objectives. Intravenous immunoglobulin (IVIG) therapy has been reported to be effective for reducing the incidence of coronary artery lesions in Kawasaki disease (KD), an acute febrile vasculitis of...
Pickering-Brown, S. M., Baker, M., Nonaka, T., Ikeda, K., Sharma, S., Mackenzie, J., ...
In this report, we describe the clinical and neuropathological features of a case of familial frontotemporal dementia (FTD), with onset at 58 years of age and disease duration of 10 years, associated...
Serum soluble CTLA-4 levels are increased in diffuse cutaneous systemic sclerosis (2004)
Sato, S., Fujimoto, M., Hasegawa, M., Komura, K., Yanaba, K., Hayakawa, I., ...
Objective. To determine serum levels of soluble cytotoxic T-lymphocyte associated molecule-4 (sCTLA-4) and clinical association in patients with systemic sclerosis (SSc). Methods. Serum sCTLA-4...
Pickering-Brown, S. M., Baker, M., Nonaka, T., Ikeda, K., Sharma, S., Mackenzie, J., ...
In this report, we describe the clinical and neuropathological features of a case of familial frontotemporal dementia (FTD), with onset at 58 years of age and disease duration of 10 years, associated...
Serum soluble CTLA-4 levels are increased in diffuse cutaneous systemic sclerosis (2004)
Sato, S., Fujimoto, M., Hasegawa, M., Komura, K., Yanaba, K., Hayakawa, I., ...
Objective. To determine serum levels of soluble cytotoxic T-lymphocyte associated molecule-4 (sCTLA-4) and clinical association in patients with systemic sclerosis (SSc). Methods. Serum sCTLA-4...
Ichiyama, T., Ueno, Y., Hasegawa, M., Ishikawa, Y., Matsubara, T., Furukawa, S.
Objectives. Intravenous immunoglobulin (IVIG) therapy has been reported to be effective for reducing the incidence of coronary artery lesions in Kawasaki disease (KD), an acute febrile vasculitis of...
Different particle alignments in N \approx Z Ru isotopes studied by the shell model (2003)
Hasegawa, M., Kaneko, K., Mizusaki, T., Tazaki, S.
Experimentally observed heaviest $N \approx Z$ nuclei, Ru isotopes, are investigated by the shell model on a spherical basis with the extended $P+QQ$ Hamiltonian. The energy levels of all the Ru...
Antiferromagnetic Vortex Core of Tl_2Ba_2CuO_{6+x} Studied by Nuclear Magnetic Resonance (2003)
Kakuyanagi, K., Kumagai, K., Matsuda, Y., Hasegawa, M.
Spatially-resolved NMR is used to probe the magnetism in and around vortex cores of nearly optimally-doped Tl_2Ba_2CuO_{6+x} (Tc=85 K). The NMR relaxation rate 1/T_1 at Tl site provides a direct...
Indications of neutrino oscillation in a 250 km long-baseline experiment (2003)
Aoki, S, Bhang, H, Casper, D, Choi, J H, ...
The K2K experiment observes indications of neutrino oscillation: a reduction of nu(mu) flux together with a distortion of the energy spectrum. Fifty-six beam neutrino events are observed in...
Overview of steady state tokamak plasma experiments in TRIAM-1M (2003)
Zushi, H, Itoh, S, Hanada, K, Nakamura, K, Sakamoto, M, Jotaki, E, ...
Human papillomavirus type 16 and squamous cell carcinoma of the head and neck (2002)
Ringstrom, E, Peters, E, Hasegawa, M, Posner, M, Liu, M, Kelsey, KT
Purpose: Human papillomavirus (HPV) has previously been reported to be associated with squamous cell carcinoma of the head and neck. Our objective was to investigate the presence and type of HPV...
Martin,W., Rujan,T., Richly,E., Hansen,A., Cornelsen,S., Lins,T., ...
Chloroplasts were once free-living cyanobacteria that became endosymbionts, but the genomes of contemporary plastids encode only approximate to5-10% as many genes as those of their free- living...
Kakuyanagi, K., Kumagai, K., Matsuda, Y., Hasegawa, M.
Spatially-resolved NMR is used to probe the magnetism in and around the vortex core of nearly optimally-doped Tl_2Ba_2CuO_{6+\delta} (T_c=85K). The NMR relaxation rate T_1^{-1} at ^{205}Tl site, at...
Matsuda, Y., Shibata, A., Izawa, K., Ikuta, H., Hasegawa, M., Kato, Y.
We report the free flux flow (FFF) resistivity associated with a purely viscous motion of the vortices in moderately clean d-wave superconductor Bi:2201 in the strongly overdoped regime (T_c=16K) for...
Patterns of gene promoter methylation in squamous cell cancer of the head and neck (2002)
Hasegawa, M, Nelson, HH, Peters, E, Ringstrom, E, Posner, M, Kelsey, KT
Promoter methylation is an important pathway in transcriptional silencing of known and candidate tumor suppressor genes in Head and Neck Squamous Cell Carcinoma (HNSCC). In order to study the...
Martin, W., Rujan, T., Richly, E., Hansen, A., Cornelsen, S., Lins, T., ...
Chloroplasts were once free-living cyanobacteria that became endosymbionts, but the genomes of contemporary plastids encode only approximate to5-10% as many genes as those of their free- living...
Tree use and home range of the koala at Blair Athol, Central Queensland (2002)
Ellis, W. A. H., Carrick, F. N., Hasegawa, M.
Free-ranging koalas (Phascolarctos cinereus) were monitored by means of radio-relocation in the area of Blair Athol Coal Mine and surrounding properties. Daytime tree use, home range and diet of...
Ellis, W. A. H., Melzer, A., Carrick, F. N., Hasegawa, M.
Free-ranging koalas (Phascolarctos cinereus) were monitored by means of radio-relocation in the area of Blair Athol Coal Mine and surrounding properties. Daytime tree use, home range and diet of...
Ellis, W. A. H., Melzer, A., Carrick, F. N., Hasegawa, M.
Free-ranging koalas (Phascolarctos cinereus) were monitored by means of radio-relocation in the area of Blair Athol Coal Mine and surrounding properties. Daytime tree use, home range and diet of...
Tree use and home range of the koala at Blair Athol, Central Queensland (2002)
Ellis, W. A. H., Carrick, F. N., Hasegawa, M., Melzer, Alistair.
Free-ranging koalas (Phascolarctos cinereus) were monitored by means of radio-relocation in the area of Blair Athol Coal Mine and surrounding properties. Daytime tree use, home range and diet of...
Komura, K., Sato, S., Fujimoto, M., Hasegawa, M., Takehara, K.
Objective. To determine serum levels of soluble CD44 (sCD44), one of the adhesion molecules that regulate the migration of leucocytes, and clinical associations of these levels in patients...
Aspects of the ecology of koalas at Blair Athol Coal Mine (2001)
Ellis, W. A. H., Hale, P. T., Carrick, F. N., Hasegawa, M., Neilson, M., Esser, D.
Aspects of the ecology of koalas at Blair Athol Coal Mine (2001)
Ellis, W. A. H., Hale, P. T., Carrick, F. N., Hasegawa, M., Neilson, M., Esser, D.
Renal vascular damage in Japanese patients with systemic sclerosis (2001)
Nishijima, C., Sato, S., Hasegawa, M., Nagaoka, T., Hirata, A., Komatsu, K., ...
Objective. To evaluate renal vascular damage in Japanese patients with systemic sclerosis (SSc) by colour‐flow Doppler ultrasonography. Methods. The pulsatility index...
Sato, S., Hamaguchi, Y., Hasegawa, M., Takehara, K.
Objective. To determine the clinical associations of the levels of anti‐topoisomerase I (topo I) antibody in patients with systemic sclerosis (SSc)....
Improvement of the extended P+QQ interaction by modifying the monopole field (2000)
Hasegawa, M., Kaneko, K., Tazaki, S.
The extended pairing plus $QQ$ interaction with the $J$-independent isoscalar proton-neutron force as an average monopole field, which has succeeded in describing collective yrast states of $N...
Application of the extended P+QQ force model to $N \approx Z$ fp shell nuclei (1999)
Hasegawa, M., Kaneko, K., Tazaki, S.
To study collective motion, the extended pairing plus $QQ$ force model proposed recently is applied to $A$=46, 48 and 50 nuclei in the $fp$ shell region. Exact shell model calculations in the...
Global features of proton-neutron interactions and symmetry energy (1999)
We study global features of proton-neutron (p-n) interactions and symmetry energy over a wide range of nuclei, using a schematic model interaction with four forces proposed recently. Calculations are...
Roles of proton-neutron interactions in alpha-like four-nucleon correlations (1999)
An extended pairing plus QQ force model, which has been shown to successfully explain the nuclear binding energy and related quantities such as the symmetry energy, is applied to study the alpha-like...
Proton-neutron interactions in N \approx Z nuclei (1999)
Proton-neutron (p-n) interactions and its various aspects in $N\approx Z$ nuclei of $g_{9/2}$- and $f_{7/2}$ subshell are studied using a schematic model interaction with four force parameters...
Rizzu, P., Swieten, J.C. Van, Joosse, M., Hasegawa, M., Tibben, A., Niermeijer, M.F., ...
Mutations in microtubule-associated protein tau recently have been identified in familial cases of frontotemporal dementia (FTD). We report the frequency of tau mutations in a large population-based...
Rizzu, P., Hillebrand, M., Ravid, R., Heutink, P., Oostra, B.A., Duijn, C.M. Van, ...
Mutations in microtubule-associated protein tau recently have been identified in familial cases of frontotemporal dementia (FTD). We report the frequency of tau mutations in a large population-based...
Oxide Dispersion in an Amorphous Magnetic Composite. (1998)
Kimura, H., Masumoto, T., Hasegawa, M.
Using a commonly known chill block melt-spinning technique by kimura et al, an amorphous metal matrix composite has been recently developed. in an attempt to overcome the disadvantages, we introduce...
NOVAS APLICAÇÕES DE SISTEMAS SFE" HOME MADE".: II. PLANTAS DA AMÉRICA DO SUL (1997)
LANÇAS,Fernando M., VILEGAS,Janete H.Y., NOSSACK,A.C., VASCONCELOS,Eliane C., CELEGHINI,Renata M.S., CAPPELARO,E.A., ...
O Laboratório de Cromatografia do IQSC-USP tem desenvolvido pesquisas em conjunto com outros grupos de pesquisa do Brasil e da América Latina, visando a futura implantação da SFE (extração com...
Magnetic resonance imaging was used to measure atrial volumes and emptying fractions in healthy volunteers to establish normal ranges and also in patients with myocardial infarction. Fourteen healthy...
EFFECTS OF PINDOLOL ON THE CARDIOVASCULAR RESPONSE TO TRACHEAL INTUBATION (1991)
MIKAWA, K., MAEKAWA, N., GOTO, R., KAETSU, H., HASEGAWA, M., YAKU, H., ...
Laryngoscopy and tracheal intubation often cause hypertension and tachycardia, which may be exaggerated during rapid-sequnce induction of anaesthesia.We was studied the efficacy pindolol in...
Hasegawa, M., Goto, T., Mizutani, U.
We have studied the magnetic and electronic structures of 3d-transition metal pseudobinary amorphous alloys, particularly for (Co1-xbx)77B13Si10 containing Co as one of the partner elements and b =...
Hasegawa, M., Goto, T., Mizutani, U.
We have studied the magnetic and electronic structures of 3d-transition metal pseudobinary amorphous alloys, particularly for (Co1-xbx)77B13Si10 containing Co as one of the partner elements and b =...
Hasegawa, M., Goto, T., Mizutani, U.
We have studied the magnetic and electronic structures of 3d-transition metal pseudobinary amorphous alloys, particularly for (Co1-xbx)77B13Si10 containing Co as one of the partner elements and b =...
Bifurcation of magnetized electron transport in laser-produced plasmas. (1987)
Physical Review Letters, 57(1986) S.2667-70
BULK MODULI OF LIQUID METALS BY THE HOMOGENEOUS DEFORMATION AND LONG WAVE METHODS (1980)
No abstract available
BULK MODULI OF LIQUID METALS BY THE HOMOGENEOUS DEFORMATION AND LONG WAVE METHODS (1980)
No abstract available
BULK MODULI OF LIQUID METALS BY THE HOMOGENEOUS DEFORMATION AND LONG WAVE METHODS (1980)
No abstract available
Wada, A, Hirayama, T, Kitaura, H, Fujisawa, J, Hasegawa, M, Hidaka, Y, ...
Guanylyl cyclase C (STaR), a receptor protein for heat-stable enterotoxin (STa) elaborated by Escherichia coli, is associated with and spans the plasma membrane of mammalian intestinal cells. The...
Sakurada, K, Ohta, T, Fujishiro, K, Hasegawa, M, Aisaka, K
We have cloned a gene (aphA) encoding acetylpolyamine amidohydrolase from Mycoplana ramosa ATCC 49678, (previously named Mycoplana bullata). A genomic library of M. ramosa was screened with an...
Sakurada, K, Ohta, T, Hasegawa, M
We have cloned the Micromonospora viridifaciens neuraminidase (EC 3.2.1.18) gene (nedA) in Streptomyces lividans. This was accomplished by using the vector pIJ702 and BglII-BclI libraries of M....
Ogura, T, Niki, H, Mori, H, Morita, M, Hasegawa, M, Ichinose, C, ...
hopA mutants, which have been suggested to be defective in mini-F plasmid partitioning (H. Niki, C. Ichinose, T. Ogura, H. Mori, M. Morita, M. Hasegawa, N. Kusukawa, and S. Hiraga, J. Bacteriol....
A novel, highly efficient gene-cloning system for Micromonospora strains.
Hasegawa, M, Dairi, T, Ohta, T, Hashimoto, E
A highly efficient gene-cloning system for Micromonospora olivasterospora, a producer of the antibiotic fortimicin A (astromicin), suited to shotgun cloning has been developed. The system is...
Chromosomal genes essential for stable maintenance of the mini-F plasmid in Escherichia coli.
Niki, H, Ichinose, C, Ogura, T, Mori, H, Morita, M, Hasegawa, M, ...
We have isolated mutants of Escherichia coli which do not support stable maintenance of mini-F plasmids (delta ccd rep+ sop+). These host mutations, named hop, were classified into five linkage...
A receptor model for tumor promoters: rational superposition of teleocidins and phorbol esters.
Itai, A, Kato, Y, Tomioka, N, Iitaka, Y, Endo, Y, Hasegawa, M, ...
Four 12-O-tetradecanoyl-13-O-acetylphorbol-type tumor promoters--teleocidin, phorbol ester, aplysiatoxin, and ingenol ester--are superposed in an attempt to understand their common biological...
Iwabe, N, Kuma, K, Hasegawa, M, Osawa, S, Miyata, T
All extant organisms are though to be classified into three primary kingdoms, eubacteria, eukaryotes, and archaebacteria. The molecular evolutionary studies on the origin and evolution of...
Secondary structure of MS2 phage RNA and bias in code word usage.
Hasegawa, M, Yasunaga, T, Miyata, T
Based on the secondary structural model of MS2 RNA, it is shown that, in base-pairing regions of the RNA, there is a bias in the use of synonymous codons which favours C and/or G over U and/or A in...
Miyata, T, Hayashida, H, Yasunaga, T, Hasegawa, M
The pattern of codon utilization in the variable and constant regions of immunoglobulin genes are compared. It is shown that, in these regions, codon utilizations are quite distinct from one another:...
Kanno, M, Hasegawa, M, Ishida, A, Isono, K, Taniguchi, M
The mammalian mel-18/bmi-1 gene products share an amino acid sequence and a secondary structure, including a RING-finger motif, with the Drosophila Polycomb group (PcG) gene products Psc and Su(z)2,...
Uehara, Y, Hasegawa, M, Hori, M, Umezawa, H
Among a variety of anti-tumour agents tested, oxanosine and 5-azacytidine were found to be significantly more effective in inhibiting growth of rat kidney cells infected with a temperature-sensitive...
Rizzu, P, Van Swieten, J C, Joosse, M, Hasegawa, M, Stevens, M, Tibben, A, ...
Mutations in microtubule-associated protein tau recently have been identified in familial cases of frontotemporal dementia (FTD). We report the frequency of tau mutations in a large population-based...
Milinkovitch, M. C., LeDuc, R. G., Adachi, J., Farnir, F., Georges, M., Hasegawa, M.
Different phylogenetic analyses of the same genetic data set can yield conflicting results, depending on the choic of parameter settings and included taxa. This is particularly true in studies...
Hamada, M., Kido, Y., Himberg, M., Reist, J. D., Ying, C., Hasegawa, M., ...
The SmaI family of repeats is present only in the chum salmon and the pink salmon, and it is not present in five other species in the same genus or in other species in closely related genera. In the...
Molecular Mechanism of Fas ligand-induced IL-8 Production
Imamura, R., Matsumoto, N., Hasegawa, M., Konaka, K., Suda, T.
PYNOD, a Novel Apaf-1/CED4-like Protein is an Inhibitor of ASC and Caspase-1
Wang, Y., Hasegawa, M., Imamura, R., Kinoshita, T., Kondo, C., Konaka, K., ...
Wada, A, Hirayama, T, Kitaura, H, Fujisawa, J, Hasegawa, M, Hidaka, Y, ...
Guanylyl cyclase C (STaR), a receptor protein for heat-stable enterotoxin (STa) elaborated by Escherichia coli, is associated with and spans the plasma membrane of mammalian intestinal cells. The...
Sakurada, K, Ohta, T, Fujishiro, K, Hasegawa, M, Aisaka, K
We have cloned a gene (aphA) encoding acetylpolyamine amidohydrolase from Mycoplana ramosa ATCC 49678, (previously named Mycoplana bullata). A genomic library of M. ramosa was screened with an...
Sakurada, K, Ohta, T, Hasegawa, M
We have cloned the Micromonospora viridifaciens neuraminidase (EC 3.2.1.18) gene (nedA) in Streptomyces lividans. This was accomplished by using the vector pIJ702 and BglII-BclI libraries of M....
Ogura, T, Niki, H, Mori, H, Morita, M, Hasegawa, M, Ichinose, C, ...
hopA mutants, which have been suggested to be defective in mini-F plasmid partitioning (H. Niki, C. Ichinose, T. Ogura, H. Mori, M. Morita, M. Hasegawa, N. Kusukawa, and S. Hiraga, J. Bacteriol....
A novel, highly efficient gene-cloning system for Micromonospora strains.
Hasegawa, M, Dairi, T, Ohta, T, Hashimoto, E
A highly efficient gene-cloning system for Micromonospora olivasterospora, a producer of the antibiotic fortimicin A (astromicin), suited to shotgun cloning has been developed. The system is...
Chromosomal genes essential for stable maintenance of the mini-F plasmid in Escherichia coli.
Niki, H, Ichinose, C, Ogura, T, Mori, H, Morita, M, Hasegawa, M, ...
We have isolated mutants of Escherichia coli which do not support stable maintenance of mini-F plasmids (delta ccd rep+ sop+). These host mutations, named hop, were classified into five linkage...
A receptor model for tumor promoters: rational superposition of teleocidins and phorbol esters.
Itai, A, Kato, Y, Tomioka, N, Iitaka, Y, Endo, Y, Hasegawa, M, ...
Four 12-O-tetradecanoyl-13-O-acetylphorbol-type tumor promoters--teleocidin, phorbol ester, aplysiatoxin, and ingenol ester--are superposed in an attempt to understand their common biological...
Iwabe, N, Kuma, K, Hasegawa, M, Osawa, S, Miyata, T
All extant organisms are though to be classified into three primary kingdoms, eubacteria, eukaryotes, and archaebacteria. The molecular evolutionary studies on the origin and evolution of...
Secondary structure of MS2 phage RNA and bias in code word usage.
Hasegawa, M, Yasunaga, T, Miyata, T
Based on the secondary structural model of MS2 RNA, it is shown that, in base-pairing regions of the RNA, there is a bias in the use of synonymous codons which favours C and/or G over U and/or A in...
Miyata, T, Hayashida, H, Yasunaga, T, Hasegawa, M
The pattern of codon utilization in the variable and constant regions of immunoglobulin genes are compared. It is shown that, in these regions, codon utilizations are quite distinct from one another:...
Kanno, M, Hasegawa, M, Ishida, A, Isono, K, Taniguchi, M
The mammalian mel-18/bmi-1 gene products share an amino acid sequence and a secondary structure, including a RING-finger motif, with the Drosophila Polycomb group (PcG) gene products Psc and Su(z)2,...
Uehara, Y, Hasegawa, M, Hori, M, Umezawa, H
Among a variety of anti-tumour agents tested, oxanosine and 5-azacytidine were found to be significantly more effective in inhibiting growth of rat kidney cells infected with a temperature-sensitive...
Milinkovitch, M. C., LeDuc, R. G., Adachi, J., Farnir, F., Georges, M., Hasegawa, M.
Different phylogenetic analyses of the same genetic data set can yield conflicting results, depending on the choic of parameter settings and included taxa. This is particularly true in studies...
Hamada, M., Kido, Y., Himberg, M., Reist, J. D., Ying, C., Hasegawa, M., ...
The SmaI family of repeats is present only in the chum salmon and the pink salmon, and it is not present in five other species in the same genus or in other species in closely related genera. In the...
Rizzu, P, Van Swieten, J C, Joosse, M, Hasegawa, M, Stevens, M, Tibben, A, ...
Mutations in microtubule-associated protein tau recently have been identified in familial cases of frontotemporal dementia (FTD). We report the frequency of tau mutations in a large population-based...
Molecular Mechanism of Fas ligand-induced IL-8 Production
Imamura, R., Matsumoto, N., Hasegawa, M., Konaka, K., Suda, T.
PYNOD, a Novel Apaf-1/CED4-like Protein is an Inhibitor of ASC and Caspase-1
Wang, Y., Hasegawa, M., Imamura, R., Kinoshita, T., Kondo, C., Konaka, K., ...
Determination of the molecular nature and cellular localization of Thy-1 in human renal tissue
Miyata, T., Isobe, K., Dawson, R., Ritter, M. A., Inagi, R., Oda, O., ...
The molecular nature and cellular localization of Thy-1 antigen in human renal tissue were studied. Strong immunohistochemical staining was observed in frozen sections of human kidney using...
Self-energy correction to momentum-density distribution of positron-electron pairs
Tang, Z., Nagai, Y., Inoue, K., Toyama, T., Chiba, T., Saito, Mineo, ...
Positron two-dimensional angular correlation of annihilation radiation (2D ACAR), i.e., the 2D projection of the electron momentum densities sampled by positron, in Si is employed to verify the...
Antigen specificity of antihistone antibodies in systemic sclerosis
Hasegawa, M., Sato, S., Kikuchi, K., Takehara, K.
OBJECTIVES—The aim of the study was to determine the prevalence and clinical significance of antibodies to individual histone components in systemic sclerosis (SSc). METHODS—Serum samples from...
Antiphospholipid antibody in localised scleroderma
Sato, S, Fujimoto, M, Hasegawa, M, Takehara, K
Methods: Antibodies against cardiolipin (aCL) or ß2-glycoprotein I were examined by enzyme linked immunosorbent assay (ELISA) in 48 patients with localised scleroderma (18 patients with generalised...
Kanemaru, K., Hasegawa, M., Shimada, H., Ihara, Y.
Here we report on a monoclonal antibody, H6-33, that labels various beta-amyloid plaques, including diffuse plaques in the formalin-fixed, paraffin-embedded section from the brain affected with...
Ellis, WAH, Melzer, A, Carrick, FN, Hasegawa, M
Free-ranging koalas (Phascolarctos cinereus) were monitored by means of radio-relocation in the area of Blair Athol Coal Mine and surrounding properties. Daytime tree use, home range and diet of...
Iwatsubo, T., Hasegawa, M., Esaki, Y., Ihara, Y.
Immunocytochemically, neuropil threads (curly fibers) were investigated in the Alzheimer's disease brain using a confocal laser scanning fluorescence microscope by double labeling with tau/ubiquitin...
AYUKAWA, H, MATSUBARA, T, KANEKO, M, HASEGAWA, M, ICHIYAMA, T, FURUKAWA, S
Influenza virus and respiratory syncytial virus (RSV) are the most common causes of acute severe respiratory infection in children during the winter. There have been few reports about peripheral...
Autoantibody against matrix metalloproteinase-3 in patients with systemic sclerosis
NISHIJIMA, C, HAYAKAWA, I, MATSUSHITA, T, KOMURA, K, HASEGAWA, M, TAKEHARA, K, ...
Systemic sclerosis (SSc) is characterized by multi-organ fibrosis with an autoimmune background. Although autoantibodies are detected frequently in SSc patients, the role of autoantibody in the...
Yamada, M, Yanaba, K, Hasegawa, M, Matsushita, Y, Horikawa, M, Komura, K, ...
Malignant melanoma is often accompanied by a host response of inflammatory cell infiltration that is highly regulated by multiple adhesion molecules. To assess the role of adhesion molecules,...
HASEGAWA, M, SATO, S, TAKEHARA, K
To determine the role of chemokines in the pathogenesis of systemic sclerosis (SSc), we examined serum levels, spontaneous production by peripheral blood mononuclear cells (PBMC), and histological...
Shimada, Y, Hasegawa, M, Takehara, K, Sato, S
L-selectin is expressed on most circulating leucocytes and mediates leucocyte rolling on endothelium at sites of inflammation. Following rolling or activation of leucocytes, cell surface L-selectin...
FUJII, H, HASEGAWA, M, TAKEHARA, K, MUKAIDA, N, SATO, S
In patients with systemic sclerosis (SSc), there are conflicting findings regarding which is predominant between type 1 and type 2 immune responses. To determine the balance between type 1 and type 2...
Autoantibodies against phosphatidylserine-prothrombin complex in patients with systemic sclerosis
Hasegawa, M, Sato, S, Yanaba, K, Komura, K, Yamazaki, M, Takehara, K
Methods: Anti-PS/PT IgG Ab was examined by enzyme linked immunosorbent assay (ELISA) in 112 patients with SSc. Thirty three healthy volunteers and 30 patients with systemic lupus erythematosus (SLE)...
Up regulated expression of fractalkine/CX3CL1 and CX3CR1 in patients with systemic sclerosis
Hasegawa, M, Sato, S, Echigo, T, Hamaguchi, Y, Yasui, M, Takehara, K
Background: Fractalkine expressed on endothelial cells mediates activation and adhesion of leucocytes expressing its receptor, CX3CR1. Soluble fractalkine exhibits chemotactic activity for leucocytes...
The clinical relevance of serum antinuclear antibodies in Japanese patients with systemic sclerosis
Hamaguchi, Y, Hasegawa, M, Fujimoto, M, Matsushita, T, Komura, K, Kaji, K, ...
Yamazaki, K, Hasegawa, M, Ohoka, I, Hanami, K, Asoh, A, Nagao, T, ...
Background: The retinoblastoma (Rb) pathway, which governs cell cycle progression, is frequently genetically altered in cancer, causing deregulated expression of the E2F-1 transcription factor, which...
Sone, S, Li, F, Yang, Z-G, Honda, T, Maruyama, Y, Takashima, S, ...
The aim of this study was to evaluate the usefulness of annual screening for lung cancer by low-dose computed tomography (CT) and the characteristics of identified lung cancers. Subjects consisted of...