Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling (2004)
Himanen, JP, Chumley, MJ, Lackmann, M, Li, C, Barton, WA, Jeffrey, PD, ...
The interactions between Eph receptor tyrosine kinases and their ephrin ligands regulate cell migration and axon pathfinding. The EphA receptors are generally thought to become activated by ephrin-A...
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling (2004)
Himanen, JP, Chumley, MJ, Lackmann, M, Li, C, Barton, WA, Jeffrey, PD, ...
The interactions between Eph receptor tyrosine kinases and their ephrin ligands regulate cell migration and axon pathfinding. The EphA receptors are generally thought to become activated by ephrin-A...
Henkemeyer, M, Marengere, LE, McGlade, J, Olivier, JP, Conlon, RA, Holmyard, DP, ...
Neural kinase (Nuk) encodes a murine receptor-like tyrosine kinase belonging to the Eph/Elk/Eck family. Protein localization studies indicate that during early embryogenesis Nuk is confined to the...
Henkemeyer, M, Marengere, LE, McGlade, J, Olivier, JP, Conlon, RA, Holmyard, DP, ...
Neural kinase (Nuk) encodes a murine receptor-like tyrosine kinase belonging to the Eph/Elk/Eck family. Protein localization studies indicate that during early embryogenesis Nuk is confined to the...
A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase.
Lai, K M, Olivier, J P, Gish, G D, Henkemeyer, M, McGlade, J, Pawson, T
Antibodies to the human Shc adaptor protein were used to isolate a cDNA encoding a Drosophila Shc protein (dShc) by screening an expression library. The dshc gene, which maps to position 67B-C on the...
Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap.
Henkemeyer, M, Jacks, T, Pawson, T
The Ras guanine nucleotide-binding protein functions as a molecular switch in signalling downstream of protein-tyrosine kinases. Ras is activated by exchange of GDP for GTP and is turned off by...
Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.
Orioli, D, Henkemeyer, M, Lemke, G, Klein, R, Pawson, T
Sek4 and Nuk are members of the Eph-related family of receptor protein-tyrosine kinases. These receptors interact with a set of cell surface ligands that have recently been implicated in axon...
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.
Saxton, T M, Henkemeyer, M, Gasca, S, Shen, R, Rossi, D J, Shalaby, F, ...
Shp-1, Shp-2 and corkscrew comprise a small family of cytoplasmic tyrosine phosphatases that possess two tandem SH2 domains. To investigate the biological functions of Shp-2, a targeted mutation has...
Holland, S J, Gale, N W, Gish, G D, Roth, R A, Songyang, Z, Cantley, L C, ...
Eph-related receptor tyrosine kinases have been implicated in the control of axonal navigation and fasciculation. To investigate the biochemical mechanisms underlying such functions, we have...
A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase.
Lai, K M, Olivier, J P, Gish, G D, Henkemeyer, M, McGlade, J, Pawson, T
Antibodies to the human Shc adaptor protein were used to isolate a cDNA encoding a Drosophila Shc protein (dShc) by screening an expression library. The dshc gene, which maps to position 67B-C on the...
Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap.
Henkemeyer, M, Jacks, T, Pawson, T
The Ras guanine nucleotide-binding protein functions as a molecular switch in signalling downstream of protein-tyrosine kinases. Ras is activated by exchange of GDP for GTP and is turned off by...
Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.
Orioli, D, Henkemeyer, M, Lemke, G, Klein, R, Pawson, T
Sek4 and Nuk are members of the Eph-related family of receptor protein-tyrosine kinases. These receptors interact with a set of cell surface ligands that have recently been implicated in axon...
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.
Saxton, T M, Henkemeyer, M, Gasca, S, Shen, R, Rossi, D J, Shalaby, F, ...
Shp-1, Shp-2 and corkscrew comprise a small family of cytoplasmic tyrosine phosphatases that possess two tandem SH2 domains. To investigate the biological functions of Shp-2, a targeted mutation has...
Holland, S J, Gale, N W, Gish, G D, Roth, R A, Songyang, Z, Cantley, L C, ...
Eph-related receptor tyrosine kinases have been implicated in the control of axonal navigation and fasciculation. To investigate the biochemical mechanisms underlying such functions, we have...