M. Hibi

Publication List Details

Period

1998 - 1998

Number

17

Co-Authors

Heat Transmission During Thermal Shock Testing of Ceramics. (1998)

Nishikawa, T., Gao, T., Hibi, M., Takatsu, M., Ogawa, M.

The thermal shock resistance of ceramics is generally evaluated by the water-quench test, in which it is important and necessary to understand the heat-transmission behavior. A novel and simple...

Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.

Westwick, J K, Cox, A D, Der, C J, Cobb, M H, Hibi, M, Karin, M, ...

c-Jun transcriptional activity is augmented by expression of oncogenic Ras and Raf proteins. This study demonstrates a direct correlation between Ras transforming activity and c-Jun activation,...

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

Murakami, M, Narazaki, M, Hibi, M, Yawata, H, Yasukawa, K, Hamaguchi, M, ...

Interleukin 6 (IL-6) signal is transduced through gp130 that associates with a complex of IL-6 and IL-6 receptor. Truncations or amino acid substitutions offe introduced in the cytoplasmic region of...

Altering the specificity of signal transduction cascades: positive regulation of c-Jun transcriptional activity by protein kinase A.

Smeal, T, Hibi, M, Karin, M

Protein phosphorylation is commonly used to modulate transcription factor activity. However, all existing genetic evidence for stimulation of transcription factor activity by phosphorylation rests on...

Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130.

Yawata, H, Yasukawa, K, Natsuka, S, Murakami, M, Yamasaki, K, Hibi, M, ...

Here, we report the analysis of the structure-function relationship of the extracellular region of human interleukin 6 receptor (IL-6R). Upon binding of IL-6, IL-6R becomes associated extracellularly...

Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation.

Yamanaka, Y, Nakajima, K, Fukada, T, Hibi, M, Hirano, T

Interleukin-6 (IL-6) induces growth arrest and macrophage differentiation through its receptor in a murine myeloid leukaemic cell line, M1, although it is largely unknown how the IL-6 receptor...

A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells.

Nakajima, K, Yamanaka, Y, Nakae, K, Kojima, H, Ichiba, M, Kiuchi, N, ...

Interleukin-6 (IL-6) induces either differentiation or growth of a variety of cells. Little is known about the molecular basis of this cellular decision. The family of signal transducer and activator...

Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

Ihara, S, Nakajima, K, Fukada, T, Hibi, M, Nagata, S, Hirano, T, ...

IL-6 induces differentiation of PC12 cells pretreated with nerve growth factor (NGF). We explored the signals required for neurite outgrowth of PC12 cells by using a series of mutants of a chimeric...

STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition.

Fukada, T, Ohtani, T, Yoshida, Y, Shirogane, T, Nishida, K, Nakajima, K, ...

The signal transducer and activator of transcription molecules (STATs) play key roles in cytokine-induced signal transduction. However, their role in cell growth has not been clear. In the present...

Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.

Westwick, J K, Cox, A D, Der, C J, Cobb, M H, Hibi, M, Karin, M, ...

c-Jun transcriptional activity is augmented by expression of oncogenic Ras and Raf proteins. This study demonstrates a direct correlation between Ras transforming activity and c-Jun activation,...

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

Murakami, M, Narazaki, M, Hibi, M, Yawata, H, Yasukawa, K, Hamaguchi, M, ...

Interleukin 6 (IL-6) signal is transduced through gp130 that associates with a complex of IL-6 and IL-6 receptor. Truncations or amino acid substitutions offe introduced in the cytoplasmic region of...

Altering the specificity of signal transduction cascades: positive regulation of c-Jun transcriptional activity by protein kinase A.

Smeal, T, Hibi, M, Karin, M

Protein phosphorylation is commonly used to modulate transcription factor activity. However, all existing genetic evidence for stimulation of transcription factor activity by phosphorylation rests on...

Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130.

Yawata, H, Yasukawa, K, Natsuka, S, Murakami, M, Yamasaki, K, Hibi, M, ...

Here, we report the analysis of the structure-function relationship of the extracellular region of human interleukin 6 receptor (IL-6R). Upon binding of IL-6, IL-6R becomes associated extracellularly...

Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation.

Yamanaka, Y, Nakajima, K, Fukada, T, Hibi, M, Hirano, T

Interleukin-6 (IL-6) induces growth arrest and macrophage differentiation through its receptor in a murine myeloid leukaemic cell line, M1, although it is largely unknown how the IL-6 receptor...

A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells.

Nakajima, K, Yamanaka, Y, Nakae, K, Kojima, H, Ichiba, M, Kiuchi, N, ...

Interleukin-6 (IL-6) induces either differentiation or growth of a variety of cells. Little is known about the molecular basis of this cellular decision. The family of signal transducer and activator...

Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

Ihara, S, Nakajima, K, Fukada, T, Hibi, M, Nagata, S, Hirano, T, ...

IL-6 induces differentiation of PC12 cells pretreated with nerve growth factor (NGF). We explored the signals required for neurite outgrowth of PC12 cells by using a series of mutants of a chimeric...

STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition.

Fukada, T, Ohtani, T, Yoshida, Y, Shirogane, T, Nishida, K, Nakajima, K, ...

The signal transducer and activator of transcription molecules (STATs) play key roles in cytokine-induced signal transduction. However, their role in cell growth has not been clear. In the present...