M. Hosokawa

Publication List Details

Period

1991 - 2008

Number

34

Co-Authors

DECIGO pathfinder (2008)

Ando, M., Kawamura, Seiji, Nakamura, T., Tsubono, K., Tanaka, T., Funaki, I., ...

DECIGO pathfinder (DPF) is a milestone satellite mission for DECIGO (DECi-hertz Interferometer Gravitational wave Observatory) which is a future space gravitational wave antenna. DECIGO is expected...

The Japanese space gravitational wave antenna: DECIGO (2008)

Kawamura, Seiji, Ando, M., Nakamura, T., Tsubono, K., Tanaka, T., Funaki, I., ...

DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese space gravitational wave antenna. DECIGO is expected to open a new window of observation for gravitational...

The Japanese space gravitational wave antenna - DECIGO (2008)

Kawamura, Seiji, Ando, M., Nakamura, T., Tsubono, K., Tanaka, T., Funaki, I., ...

DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese space gravitational wave antenna. The goal of DECIGO is to detect gravitational waves from various kinds of...

Docosahexaenoic acid and eicosapentaenoic acid-enriched phosphatidylcholine liposomes enhance the permeability, transportation and uptake of phospholipids in Caco-2 cells (2006)

Hossain, Z, Kurihara, H, Hosokawa, M, Takahashi, K, 栗原, 秀幸

The influence of docosahexaenoic acid (DHA)- and eicosapentaenoic acid (EPA)-enriched phosphatidylcholine (PC) on the permeability, transport and uptake of phospholipids was evaluated in Caco-2...

Docosahexaenoic acid and eicosapentaenoic acid-enriched phosphatidylcholine liposomes enhance the permeability, transportation and uptake of phospholipids in Caco-2 cells (2006)

Hossain, Z, Kurihara, H, Hosokawa, M, Takahashi, K

The influence of docosahexaenoic acid (DHA)- and eicosapentaenoic acid (EPA)-enriched phosphatidylcholine (PC) on the permeability, transport and uptake of phospholipids was evaluated in Caco-2...

Docosahexaenoic acid and eicosapentaenoic acid-enriched phosphatidylcholine liposomes enhance the permeability, transportation and uptake of phospholipids in Caco-2 cells (2006)

Hossain, Z, Kurihara, H, Hosokawa, M, Takahashi, K

The influence of docosahexaenoic acid (DHA)- and eicosapentaenoic acid (EPA)-enriched phosphatidylcholine (PC) on the permeability, transport and uptake of phospholipids was evaluated in Caco-2...

Growth inhibition and apoptosis induction by all-trans-conjugated linolenic acids on human colon cancer cells (2006)

Yasui, Y., Hosokawa, M., Kohno, H., Tanaka, T., Miyashita, K.

Conjugated linolenic acids (CLN) are geometric and positional isomers of linolenic acid. Growth inhibition and apoptosis induction by alpha-eleostearic acid (c9,t11,t13-CLN), beta-eleostearic acid...

Growth inhibition and apoptosis induction by all-trans-conjugated linolenic acids on human colon cancer cells. (2006)

Yasui, Y., Hosokawa, M., Kohno, H., Tanaka, T., Miyashita, K.

Conjugated linolenic acids (CLN) are geometric and positional isomers of linolenic acid. Growth inhibition and apoptosis induction by alpha-eleostearic acid (c9,t11,t13-CLN), beta-eleostearic acid...

Growth inhibition and apoptosis induction by all-trans-conjugated linolenic acids on human colon cancer cells. (2006)

Yasui, Y., Hosokawa, M., Kohno, H., Tanaka, T., Miyashita, K.

Conjugated linolenic acids (CLN) are geometric and positional isomers of linolenic acid. Growth inhibition and apoptosis induction by alpha-eleostearic acid (c9,t11,t13-CLN), beta-eleostearic acid...

The Japanese space gravitational wave antenna - DECIGO (2006)

Kawamura, Seiji, Nakamura, T., Ando, M., Seto, N., Tsubono, K., Numata, K., ...

DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese space gravitational wave antenna. It aims at detecting various kinds of gravitational waves between 1 mHz and...

On Optimizing the Configuration of Time-Transfer Links Used to Generate TAI (2006)

Matsakis, D., Arias, F., Bauch, A., Davis, J., Gotoh, T., Hosokawa, M., ...

Recent work on the uncertainties of [UTC-UTC(kappa)] has made it possible to quantify the effects of different configurations of the time-transfer links used to generate International Atomic Time...

Peroxisome Proliferator-Activated Receptor-¿-Null Mice Have Increased White Adipose Tissue Glucose Utilization, GLUT4, and Fat Mass: Role in Liver and Brain (2006)

Knauf, C., Rieusset, J., Foretz, M., Cani, P.D., Uldry, M., Hosokawa, M., ...

Activation of the peroxisome proliferator-activated receptor (PPAR)-¿ increases lipid catabolism and lowers the concentration of circulating lipid, but its role in the control of glucose metabolism...

Accumulation of pro-apolipoprotein A-II in mouse senile amyloid fibrils.

Higuchi, K, Kogishi, K, Wang, J, Xia, C, Chiba, T, Matsushita, T, ...

Apolipoprotein A-II (apoA-II), the major apoprotein of serum high-density lipoprotein, is deposited as amyloid fibrils (AApoAII) in murine senile amyloidosis. We have identified and purified a more...

Polymorphism of apolipoprotein A-II (apoA-II) among inbred strains of mice. Relationship between the molecular type of apoA-II and mouse senile amyloidosis.

Higuchi, K, Kitagawa, K, Naiki, H, Hanada, K, Hosokawa, M, Takeda, T

Three types of apolipoprotein A-II (apoA-II) proteins (A, B and C) were predicted from the nucleotide sequence of apoA-II cDNA. Substitution of amino acid residues was noted at four positions (type...

Genetic analysis of HLA, NA and HPA typing in type 2 diabetes and ASO

Nomura, S, Shouzu, A, Omoto, S, Matsuzaki, T, Yamaoka, M, Abe, M, ...

We examined the genetic status of human leucocyte antigens (HLA), human platelet alloantigens (HPA) and neutrophil-specific antigens (NA) in patients with type 2 diabetes mellitus and diabetic...

Polymorphism of apolipoprotein A-II (apoA-II) among inbred strains of mice. Relationship between the molecular type of apoA-II and mouse senile amyloidosis.

Higuchi, K, Kitagawa, K, Naiki, H, Hanada, K, Hosokawa, M, Takeda, T

Three types of apolipoprotein A-II (apoA-II) proteins (A, B and C) were predicted from the nucleotide sequence of apoA-II cDNA. Substitution of amino acid residues was noted at four positions (type...

Accumulation of pro-apolipoprotein A-II in mouse senile amyloid fibrils.

Higuchi, K, Kogishi, K, Wang, J, Xia, C, Chiba, T, Matsushita, T, ...

Apolipoprotein A-II (apoA-II), the major apoprotein of serum high-density lipoprotein, is deposited as amyloid fibrils (AApoAII) in murine senile amyloidosis. We have identified and purified a more...

Genetic analysis of HLA, NA and HPA typing in type 2 diabetes and ASO

Nomura, S, Shouzu, A, Omoto, S, Matsuzaki, T, Yamaoka, M, Abe, M, ...

We examined the genetic status of human leucocyte antigens (HLA), human platelet alloantigens (HPA) and neutrophil-specific antigens (NA) in patients with type 2 diabetes mellitus and diabetic...

Protein kinase C mediates the signal for interferon-gamma mRNA expression in cytotoxic T cells after their adhesion to laminin.

Li, Y Q, Kobayashi, M, Yuan, L, Wang, J, Matsushita, K, Hamada, J I, ...

A cytotoxic T-cell line, CTLL-2 cells, showed spreading after adhering to extracellular matrix proteins such as fibronectin (FN), laminin (LN) and hyarulonic acid (HA). The adhesion of CTLL-2 cells...

Age-related changes in the temporomandibular joint of the senescence accelerated mouse. SAM-P/3 as a new murine model of degenerative joint disease.

Chen, W. H., Hosokawa, M., Tsuboyama, T., Ono, T., Iizuka, T., Takeda, T.

Age-related changes of the condyle of the temporomandibular joint (TMJ) in strains of Senescence Accelerated Mouse (SAM) were investigated. With advancing age, all strains of SAM showed degenerative...

Metabolism of senile amyloid precursor and amyloidogenesis. Age-related acceleration of apolipoprotein A-II clearance in the senescence accelerated mouse.

Naiki, H., Higuchi, K., Yonezu, T., Hosokawa, M., Takeda, T.

Serum clearance kinetics of murine senile amyloid-related high-density lipoprotein (HDL) apoprotein A-II (apo A-II) was examined in the senescence-accelerated mouse, prone (SAM-P/1) and resistant...

Morphologic demonstration of cytoplasmic ASSAM-related antigenic substance (CASSAM) by an immunoperoxidase technique.

Takeshita, S., Higuchi, K., Hosokawa, M., Matsumura, A., Higuchi, K., Kohno, A., ...

Murine senile amyloid protein identified in the senescence-accelerated mouse (SAM) was called ASSAM, and the ASSAM-related antigenic substance was detected in the cytoplasm of hepatocytes, columnar...

Anti-tumour immunity by normal allogeneic blood transfusion in rat.

Oikawa, T, Hosokawa, M, Imamura, M, Sendo, F, Nakayama, M

Growth of transplantable KMT-17 tumour in syngeneic WKA/MK rats was inhibited by i.v. preimmunization with whole blood from normal rats of allogeneic strains. The inhibitory effect was also observed...

Nitric oxide-mediated inhibitory response of rat proximal colon: independence from changes in membrane potential.

Suthamnatpong, N., Hosokawa, M., Takeuchi, T., Hata, F., Takewaki, T.

1. We studied the relation of nitric oxide-mediated relaxation of smooth muscle to changes in membrane potential of cells in the proximal colon of rats. 2. The resting membrane potential and...

Tumour matrilysin expression predicts metastatic potential of stage I (pT1) colon and rectal cancers

Kurokawa, S, Arimura, Y, Yamamoto, H, Adachi, Y, Endo, T, Sato, T, ...

Background and aims: Nodal metastases are indisputable determinants of prognosis for colon and rectal cancer. Using classical histological criteria, many attempts to predict nodal metastasis have...

Malignant progression of a mouse fibrosarcoma by host cells reactive to a foreign body (gelatin sponge).

Okada, F., Hosokawa, M., Hamada, J. I., Hasegawa, J., Kato, M., Mizutani, M., ...

The QR regressor tumour (QR-32), a fibrosarcoma which is unable to grow progressively in normal syngeneic C57BL/6 mice, was able to grow progressively in 13 out of 22 mice (59%) when it was...

Enhancement of in vitro prostaglandin E2 production by mouse fibrosarcoma cells after co-culture with various anti-tumour effector cells.

Okada, F., Hosokawa, M., Hasegawa, J., Kuramitsu, Y., Nakai, K., Yuan, L., ...

We have previously reported that an increase in the production of immunosuppressive prostaglandin E2 by a QR tumour (QR-32) is accompanied by progressive growth of the tumour in syngeneic C57BL/6...

Transforming growth factor beta 1 (TGF-beta 1) produced in tumour tissue after chemotherapy acts as a lymphokine-activated killer attractant.

Kuramitsu, Y., Nishibe, M., Kobayashi, M., Togashi, Y., Yuan, L., Takizawa, M., ...

Using an under agarose migration (UAM) assay, we studied lymphokine-activated killer (LAK)-attractant activity in cultured conditioned medium of tumour tissues after chemotherapy as a possible...

Inhibitory effects of malotilate on invasion and metastasis of rat mammary carcinoma cells by modifying the functions of vascular endothelial cells.

Nagayasu, H., Hamada, J., Kawano, T., Konaka, S., Nakata, D., Shibata, T., ...

Malotilate (diisopropyl,1,3-dithiol-2-ylidenemalonate, MT) is clinically used as a hepatoprotective agent. Because we noticed that MT induced the differentiation of cultured vascular endothelial...

Prevention of inflammation-mediated acquisition of metastatic properties of benign mouse fibrosarcoma cells by administration of an orally available superoxide dismutase

Okada, F, Shionoya, H, Kobayashi, M, Kobayashi, T, Tazawa, H, Onuma, K, ...

Weakly tumorigenic and nonmetastatic QR-32 cells derived from a fibrosarcoma in C57BL6 mouse are converted to malignant cells once they have grown after being coimplanted with a gelatine sponge which...

Inflammatory cell-mediated tumour progression and minisatellite mutation correlate with the decrease of antioxidative enzymes in murine fibrosarcoma cells

Okada, F, Nakai, K, Kobayashi, T, Shibata, T, Tagami, S, Kawakami, Y, ...

We isolated six clones of weakly tumorigenic fibrosarcoma (QR) from the tumorigenic clone BMT-11 cl-9. The QR clones were unable to grow in normal C57BL/6 mice when injected s.c. (1 × 105 cells)....

DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers

Satoh, A, Toyota, M, Itoh, F, Kikuchi, T, Obata, T, Sasaki, Y, ...

Death-associated protein kinase is a positive regulator of programmed cell death induced by interferon γ. To investigate the role of epigenetic inactivation of death-associated protein kinase in...

Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells

Niizeki, H, Kobayashi, M, Horiuchi, I, Akakura, N, Chen, J, Wang, J, ...

The incidence of distant metastases is higher in the tumours with low oxygen pressure than in those with high oxygen pressure. It is well known that hypoxia induces the transcription of various genes...