M. I. Lerman

Publication List Details

Period

1977 - 2002

Number

185

Co-Authors

These include: (2002)

Email Alerting, M Zatyka, C Morrissey, I Kuzmin, M I Lerman, F Latif, ...

Genetic and functional analysis of the von

Metabolic heterogeneity of nuclear poly (A)-containing RNA in mouse liver (1977)

Chemovskaya, T. V., Lerman, M. I.

The analysis by the approach to equilibrium labeling method has shown that the poly(A)+ fraction of liver hnRNA is not a uniform class of molecules, but is comprised of two distinct subclasses with...

Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns.

Sekido, Y, Bader, S, Latif, F, Chen, J Y, Duh, F M, Wei, M H, ...

Semaphorins and collapsins make up a family of conserved genes that encode nerve growth cone guidance signals. We have identified two additional members of the human semaphorin family [human...

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.

Herman, J G, Latif, F, Weng, Y, Lerman, M I, Zbar, B, Liu, S, ...

Mutational inactivation and allelic loss of the von Hippel-Lindau (VHL) gene appear to be causal events for the majority of spontaneous clear-cell renal carcinomas. We now show that hypermethylation...

Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer.

Makos, M, Nelkin, B D, Lerman, M I, Latif, F, Zbar, B, Baylin, S B

Regional increases in DNA methylation occur in normally unmethylated cytosine-rich areas in neoplastic cells. These changes could potentially alter chromatin structure to inactivate gene...

Homology between the KpnI primate and BamH1 (M1F-1) rodent families of long interspersed repeated sequences.

Singer, M F, Thayer, R E, Grimaldi, G, Lerman, M I, Fanning, T G

The KpnI and BamH1 (or M1F-1) families are the predominant sets of long interspersed repeated DNA sequences (LINEs) in primates and rodents, respectively. Recently, the sequences of several cloned...

Metabolic heterogeneity of nuclear poly (A)-containing RNA in mouse liver.

Chernovskaya, T V, Lerman, M I

The analysis by the approach to equilibrium labeling method has shown that the poly(A)+ fraction of liver hnRNA is not a uniform class of molecules, but is comprised of two distinct subclasses with...

A transforming activity not detected by DNA transfer to NIH 3T3 cells is detected by JB6 mouse epidermal cells.

Colburn, N H, Lerman, M I, Hegamyer, G A, Gindhart, T D

Transfection of four different mouse epidermal tumor cell DNAs into NIH 3T3 cells yielded neither morphologically altered foci nor anchorage independence. However, promotion-sensitive, but not...

Unusual class of Alu sequences containing a potential Z-DNA segment.

Saffer, J D, Lerman, M I

A potential Z-DNA sequence, (dA-dC)9, has been found to replace the customary A-rich region in the middle of an Alu family member in the African green monkey genome. This Alu, bounded by imperfect...

Kpn I family of long interspersed repeated DNA sequences in primates: polymorphism of family members and evidence for transcription.

Lerman, M I, Thayer, R E, Singer, M F

An approximately equal to 2-kilobase-pair-long member (Kpn I-LS1) of the African green monkey Kpn I family of repeated sequences has been cloned, subjected to sequence analysis, and compared to other...

Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns.

Sekido, Y, Bader, S, Latif, F, Chen, J Y, Duh, F M, Wei, M H, ...

Semaphorins and collapsins make up a family of conserved genes that encode nerve growth cone guidance signals. We have identified two additional members of the human semaphorin family [human...

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.

Herman, J G, Latif, F, Weng, Y, Lerman, M I, Zbar, B, Liu, S, ...

Mutational inactivation and allelic loss of the von Hippel-Lindau (VHL) gene appear to be causal events for the majority of spontaneous clear-cell renal carcinomas. We now show that hypermethylation...

Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer.

Makos, M, Nelkin, B D, Lerman, M I, Latif, F, Zbar, B, Baylin, S B

Regional increases in DNA methylation occur in normally unmethylated cytosine-rich areas in neoplastic cells. These changes could potentially alter chromatin structure to inactivate gene...

Homology between the KpnI primate and BamH1 (M1F-1) rodent families of long interspersed repeated sequences.

Singer, M F, Thayer, R E, Grimaldi, G, Lerman, M I, Fanning, T G

The KpnI and BamH1 (or M1F-1) families are the predominant sets of long interspersed repeated DNA sequences (LINEs) in primates and rodents, respectively. Recently, the sequences of several cloned...

Metabolic heterogeneity of nuclear poly (A)-containing RNA in mouse liver.

Chernovskaya, T V, Lerman, M I

The analysis by the approach to equilibrium labeling method has shown that the poly(A)+ fraction of liver hnRNA is not a uniform class of molecules, but is comprised of two distinct subclasses with...

A transforming activity not detected by DNA transfer to NIH 3T3 cells is detected by JB6 mouse epidermal cells.

Colburn, N H, Lerman, M I, Hegamyer, G A, Gindhart, T D

Transfection of four different mouse epidermal tumor cell DNAs into NIH 3T3 cells yielded neither morphologically altered foci nor anchorage independence. However, promotion-sensitive, but not...

Unusual class of Alu sequences containing a potential Z-DNA segment.

Saffer, J D, Lerman, M I

A potential Z-DNA sequence, (dA-dC)9, has been found to replace the customary A-rich region in the middle of an Alu family member in the African green monkey genome. This Alu, bounded by imperfect...

Kpn I family of long interspersed repeated DNA sequences in primates: polymorphism of family members and evidence for transcription.

Lerman, M I, Thayer, R E, Singer, M F

An approximately equal to 2-kilobase-pair-long member (Kpn I-LS1) of the African green monkey Kpn I family of repeated sequences has been cloned, subjected to sequence analysis, and compared to other...

Expression of the Von Hippel-Lindau tumor suppressor gene, VHL, in human fetal kidney and during mouse embryogenesis.

Kessler, P. M., Vasavada, S. P., Rackley, R. R., Stackhouse, T., Duh, F. M., Latif, F., ...

BACKGROUND: Von Hippel-Lindau (VHL) disease is a familial cancer syndrome that has a dominant inherited pattern which predisposes affected individuals to a variety of tumours. The most frequent...

Detection of germline mutations in the von Hippel-Lindau disease gene by the primer specified restriction map modification method.

Kishida, T, Chen, F, Lerman, M I, Zbar, B

Von Hippel-Lindau disease (VHL) is an inherited disorder characterised by a predisposition to develop tumours in the eyes, central nervous system, kidneys, and adrenal glands. Recently the VHL gene...