First Results with the Modified Jet - the Jet Team (2008)
Adams, J. M., Agarici, Y., Ageladarakis, P., Alper, B., Altmann, H., Andrew, P., ...
JET was extensively modified in the 1992/93 shutdown. The new pumped divertor and many new systems were brought into operation early in 1994. Operations have progressed to 4MA plasma current and,...
JET results with the new pumped divertor and implications for ITER (2008)
Adams, J. M., Ageladarakis, P., Alper, B., Altmann, H., Andrew, P., AliArshad, S., ...
This paper presents an overview of results of the 1994/95 experimental campaign on JET with the new pumped divertor and draws implications for ITER in the areas of detached and radiative divertor...
Jones, T. T. C., Adams, J. M., Ageladarakis, P., AliArshad, S., Alper, B., Altmann, H., ...
Planned experiments in the Joint European Torus [Plasma Physics and Controlled Fusion Research, Proceedings, 13th International Conference, Washington, D.C., 1990 (International Atomic Energy Agency,...
Latest JET results in deuterium and deuterium-tritium plasmas (2008)
Adams, J. M., Ageladarakis, P., Arshad, S. A., Alper, B., Altmann, H., Andrew, P., ...
All major JET systems have been fully commissioned for D-T and the DTE1 series of experiments has started with the D-T fuel mixture and operating conditions foreseen for ITER. In the area of ITER...
Beales, P.L., Bland, E., Tobin, J.L., Bacchelli, C., Tuysuz, B., Hill, J., ...
Jeune asphyxiating thoracic dystrophy, an autosomal recessive chondrodysplasia, often leads to death in infancy because of a severely constricted thoracic cage and respiratory insufficiency; retinal...
The use of virtual prototyping and simulation in ITER maintenance device development (2007)
Esqué, S., Mattila, J., Saarinen, H., Siuko, M., Virvalo, T., Muhammad, A., ...
Fusion Engineering and Design Vol.82 Nr.15 - 24, 2073 - 2080
Meteor Burst Communications Systems. (1998)
The Earth's atmosphere is constantly bombarded by vast numbers of meteors, travelling at thousands of kilometres per hour. Upon entering the atmosphere, the friction of the air produces enough heat...
Ling, Nicholas, Shrimpton, C., Sleep, J., Kendrick-Jones, J., Irving, M.
The orientation of the light-chain region of myosin heads in relaxed, rigor, and isometrically contracting fibers from rabbit psoas muscle was studied by fluorescence polarization. Cysteine 108 of...
Meteor burst communication systems. (1989)
This document presents a summary of Meteor Burst Communication Systems, based on the results of twenty-nine papers published between 1953 and 1988. It also includes information on the various...
Linari, M., Piazzesi, G., Dobbie, I., Koubassova, N., Reconditi, M., Narayanan, T., ...
Axial x-ray diffraction patterns from single intact fibers of frog skeletal muscle were recorded by using a highly collimated x-ray beam at the European Synchrotron Radiation Facility. During...
Human Immune Response to a Plague Vaccine Comprising Recombinant F1 and V Antigens
Williamson, E. D., Flick-Smith, H. C., LeButt, C., Rowland, C. A., Jones, S. M., Waters, E. L., ...
The human immune response to a new recombinant plague vaccine, comprising recombinant F1 (rF1) and rV antigens, has been assessed during a phase 1 safety and immunogenicity trial in healthy...
Steady-state fluorescence polarization measurements provide a relatively simple method for investigating the orientation of molecular components in ordered biological systems. However, the observed...
Ling, N, Shrimpton, C, Sleep, J, Kendrick-Jones, J, Irving, M
The orientation of the light-chain region of myosin heads in relaxed, rigor, and isometrically contracting fibers from rabbit psoas muscle was studied by fluorescence polarization. Cysteine 108 of...
Allen, T S, Ling, N, Irving, M, Goldman, Y E
The orientation of the light-chain region of myosin heads in muscle fibers was followed by polarized fluorescence from an extrinsic probe during tension transients elicited by photolysis of caged...
Peckham, M, Ferenczi, M A, Irving, M
The birefringence of isolated skinned fibers from rabbit psoas muscle was measured continuously during relaxation from rigor produced by photolysis of caged ATP at sarcomere length 2.8-2.9 microns,...
Intracellular diffusion in the presence of mobile buffers. Application to proton movement in muscle.
Irving, M, Maylie, J, Sizto, N L, Chandler, W K
Junge and McLaughlin (1987) derived an expression for the apparent diffusion constant of protons in the presence of both mobile and immobile buffers. Their derivation applies only to cases in which...
Allen, T S, Sabido-David, C, Ling, N, Irving, M, Goldman, Y E
Structural changes of the myosin heads were correlated with mechanical events in the cross-bridge cycle by measuring fluorescence polarization signals at high time resolution from rhodamine probes...
Piazzesi, G, Lombardi, V, Ferenczi, M A, Thirlwell, H, Dobbie, I, Irving, M
Changes in the x-ray diffraction patterns produced by 100-microseconds-length steps imposed during tetanic stimulation were recorded from single intact fibers of frog tibialis anterior muscle. For...
Linari, M, Dobbie, I, Reconditi, M, Koubassova, N, Irving, M, Piazzesi, G, ...
Step changes in length (between -3 and +5 nm per half-sarcomere) were imposed on isolated muscle fibers at the plateau of an isometric tetanus (tension T0) and on the same fibers in rigor after...
Sabido-David, C, Brandmeier, B, Craik, J S, Corrie, J E, Trentham, D R, Irving, M
The regulatory light chain (RLC) from chicken gizzard myosin was covalently modified on cysteine 108 with either the 5- or 6-isomer of iodoacetamidotetramethylrhodamine (IATR). Labeled RLCs were...
Hopkins, S C, Sabido-David, C, Corrie, J E, Irving, M, Goldman, Y E
Fluorescence polarization was used to examine orientation changes of two rhodamine probes bound to myosin heads in skeletal muscle fibers. Chicken gizzard myosin regulatory light chain (RLC) was...
Dale, R E, Hopkins, S C, An Der Heide, U A, Marszałek, T, Irving, M, Goldman, Y E
The orientation of proteins in ordered biological samples can be investigated using steady-state polarized fluorescence from probes conjugated to the protein. A general limitation of this approach is...
The Conformation of Myosin Head Domains in Rigor Muscle Determined by X-Ray Interference
Reconditi, M., Koubassova, N., Linari, M., Dobbie, I., Narayanan, T., Diat, O., ...
In the absence of adenosine triphosphate, the head domains of myosin cross-bridges in muscle bind to actin filaments in a rigor conformation that is expected to mimic that following the working...
Delayed hypersensitivity skin testing does not influence the management of surgical patients.
Brown, R, Bancewicz, J, Hamid, J, Tillotson, G, Ward, C, Irving, M
Delayed hypersensitivity skin testing was performed at weekly intervals on 95 patients with major surgical illness. Patients with abnormal reactions on initial skin testing had a higher mortality...
1. Muscle birefringence, the difference between the refractive indices of light polarized parallel and perpendicular to the muscle fibre axis, was measured at 3 degrees C in intact single fibres...
The variation in shortening heat with sarcomere length in frog muscle.
Homsher, E, Irving, M, Lebacq, J
Pairs of frog semitendinosus muscles were stimulated tetanically for 2 s at 0 degree C and, after 0.75 s of isometric contraction, were released at constant velocity for 0.16 s. The distance...
1. Heat and work production have been measured in pairs of frog sartorius muscles undergoing two periods of rapid isovelocity shortening at 0 degrees C. The first (conditioning) shortening occurred...
1. Pairs of frog sartorius muscles were stimulated for 2 sec at 0 degrees C, after 1 sec of isometric contraction, were released at a constant velocity. The total excess heat (shortening heat) and...
Homsher, E., Irving, M., Wallner, A.
1. High-energy phosphate metabolism and energy liberated as heat and work were measured in 3 sec tetani of frog sartorius muscles at 0 °C.
The heat produced by frog muscle in a series of contractions with shortening.
Irving, M, Woledge, R C, Yamada, K
1. Heat production has been measured in muscles undergoing rapid shortening 1 sec after the start of stimulation in a 2 sec tetanus. In a series of three such tetani where the periods of shortening...
Failure of delayed hypersensitivity skin testing to predict postoperative sepsis and mortality.
Brown, R, Bancewicz, J, Hamid, J, Patel, N J, Ward, C A, Farrand, R J, ...
Delayed hypersensitivity skin reactions to a battery of recall antigens, haemoglobin and albumin concentrations, arm-muscle circumference, and percentage of ideal weight were determined before...
Accuracy of hospital activity analysis operation codes.
Whates, P D, Birzgalis, A R, Irving, M
The accuracy of operation codes on hospital activity analysis printouts has been compared with unit and patient records. Inaccurate information is being provided by the hospital activity analysis in...
Linari, M, Brunello, E, Reconditi, M, Sun, Y-B, Panine, P, Narayanan, T, ...
X-ray diffraction patterns were recorded from isolated single fibres of frog skeletal muscle during isometric contraction at temperatures between 0 and 17°C. Isometric force was 43 ± 2% (mean ±...
Surgical audit: one year's experience in a teaching hospital.
For 12 months the surgical staff at Hope Hospital have operated a form of audit. The monitored information included work load, methods of treatment, complications, misdiagnoses, and deaths. The...
Intensive investigation in management of Hodgkin's disease.
Sutcliffe, S B, Wrigley, P F, Smyth, J F, Webb, J A, Tucker, A K, Beard, M E, ...
Ninety-eight patients with clinically localised Hodgkin's disease underwent laparotomy and splenectomy to determine the extent of microscopic spread. In 68 patients the procedure was carried out for...
Linari, M., Piazzesi, G., Dobbie, I., Koubassova, N., Reconditi, M., Narayanan, T., ...
Axial x-ray diffraction patterns from single intact fibers of frog skeletal muscle were recorded by using a highly collimated x-ray beam at the European Synchrotron Radiation Facility. During...
Human Immune Response to a Plague Vaccine Comprising Recombinant F1 and V Antigens
Williamson, E. D., Flick-Smith, H. C., LeButt, C., Rowland, C. A., Jones, S. M., Waters, E. L., ...
The human immune response to a new recombinant plague vaccine, comprising recombinant F1 (rF1) and rV antigens, has been assessed during a phase 1 safety and immunogenicity trial in healthy...
1. Muscle birefringence, the difference between the refractive indices of light polarized parallel and perpendicular to the muscle fibre axis, was measured at 3 degrees C in intact single fibres...
The variation in shortening heat with sarcomere length in frog muscle.
Homsher, E, Irving, M, Lebacq, J
Pairs of frog semitendinosus muscles were stimulated tetanically for 2 s at 0 degree C and, after 0.75 s of isometric contraction, were released at constant velocity for 0.16 s. The distance...
Steady-state fluorescence polarization measurements provide a relatively simple method for investigating the orientation of molecular components in ordered biological systems. However, the observed...
Ling, N, Shrimpton, C, Sleep, J, Kendrick-Jones, J, Irving, M
The orientation of the light-chain region of myosin heads in relaxed, rigor, and isometrically contracting fibers from rabbit psoas muscle was studied by fluorescence polarization. Cysteine 108 of...
Allen, T S, Ling, N, Irving, M, Goldman, Y E
The orientation of the light-chain region of myosin heads in muscle fibers was followed by polarized fluorescence from an extrinsic probe during tension transients elicited by photolysis of caged...
Peckham, M, Ferenczi, M A, Irving, M
The birefringence of isolated skinned fibers from rabbit psoas muscle was measured continuously during relaxation from rigor produced by photolysis of caged ATP at sarcomere length 2.8-2.9 microns,...
1. Heat and work production have been measured in pairs of frog sartorius muscles undergoing two periods of rapid isovelocity shortening at 0 degrees C. The first (conditioning) shortening occurred...
1. Pairs of frog sartorius muscles were stimulated for 2 sec at 0 degrees C, after 1 sec of isometric contraction, were released at a constant velocity. The total excess heat (shortening heat) and...
Homsher, E., Irving, M., Wallner, A.
1. High-energy phosphate metabolism and energy liberated as heat and work were measured in 3 sec tetani of frog sartorius muscles at 0 °C.
The heat produced by frog muscle in a series of contractions with shortening.
Irving, M, Woledge, R C, Yamada, K
1. Heat production has been measured in muscles undergoing rapid shortening 1 sec after the start of stimulation in a 2 sec tetanus. In a series of three such tetani where the periods of shortening...
Intracellular diffusion in the presence of mobile buffers. Application to proton movement in muscle.
Irving, M, Maylie, J, Sizto, N L, Chandler, W K
Junge and McLaughlin (1987) derived an expression for the apparent diffusion constant of protons in the presence of both mobile and immobile buffers. Their derivation applies only to cases in which...
Allen, T S, Sabido-David, C, Ling, N, Irving, M, Goldman, Y E
Structural changes of the myosin heads were correlated with mechanical events in the cross-bridge cycle by measuring fluorescence polarization signals at high time resolution from rhodamine probes...
Piazzesi, G, Lombardi, V, Ferenczi, M A, Thirlwell, H, Dobbie, I, Irving, M
Changes in the x-ray diffraction patterns produced by 100-microseconds-length steps imposed during tetanic stimulation were recorded from single intact fibers of frog tibialis anterior muscle. For...
Linari, M, Dobbie, I, Reconditi, M, Koubassova, N, Irving, M, Piazzesi, G, ...
Step changes in length (between -3 and +5 nm per half-sarcomere) were imposed on isolated muscle fibers at the plateau of an isometric tetanus (tension T0) and on the same fibers in rigor after...
Sabido-David, C, Brandmeier, B, Craik, J S, Corrie, J E, Trentham, D R, Irving, M
The regulatory light chain (RLC) from chicken gizzard myosin was covalently modified on cysteine 108 with either the 5- or 6-isomer of iodoacetamidotetramethylrhodamine (IATR). Labeled RLCs were...
Hopkins, S C, Sabido-David, C, Corrie, J E, Irving, M, Goldman, Y E
Fluorescence polarization was used to examine orientation changes of two rhodamine probes bound to myosin heads in skeletal muscle fibers. Chicken gizzard myosin regulatory light chain (RLC) was...
Dale, R E, Hopkins, S C, An Der Heide, U A, Marszałek, T, Irving, M, Goldman, Y E
The orientation of proteins in ordered biological samples can be investigated using steady-state polarized fluorescence from probes conjugated to the protein. A general limitation of this approach is...
The Conformation of Myosin Head Domains in Rigor Muscle Determined by X-Ray Interference
Reconditi, M., Koubassova, N., Linari, M., Dobbie, I., Narayanan, T., Diat, O., ...
In the absence of adenosine triphosphate, the head domains of myosin cross-bridges in muscle bind to actin filaments in a rigor conformation that is expected to mimic that following the working...
Delayed hypersensitivity skin testing does not influence the management of surgical patients.
Brown, R, Bancewicz, J, Hamid, J, Tillotson, G, Ward, C, Irving, M
Delayed hypersensitivity skin testing was performed at weekly intervals on 95 patients with major surgical illness. Patients with abnormal reactions on initial skin testing had a higher mortality...
Linari, M, Brunello, E, Reconditi, M, Sun, Y-B, Panine, P, Narayanan, T, ...
X-ray diffraction patterns were recorded from isolated single fibres of frog skeletal muscle during isometric contraction at temperatures between 0 and 17°C. Isometric force was 43 ± 2% (mean ±...