M. J. Barnes

Publication List Details

Period

1962 - 2009

Number

74

Co-Authors

Measurement and analysis of SPS kicker magnet heating and outgassing with Different Bunch Spacing (2009)

Barnes, M J, Caspers, F, Cornelis, K, Ducimetière, L, Mahner, E, Papotti, G, ...

Fast kicker magnets are used to inject beam into and eject beam out of the CERN SPS accelerator ring. These kickers are generally ferrite loaded transmission line type magnets with a rectangular...

Measurement of the longitudinal and transverse impedance of kicker magnets using the coaxial wire method (2009)

Barnes, M J, Caspers, F, Kroyer, T, Métral, E, Roncarolo, F, Salvant, B

Fast kicker magnets are used to inject beam into and eject beam out of the CERN SPS accelerator ring. These kickers are generally ferrite loaded transmission line type magnets with a rectangular...

Comparison of Measured and Predicted Inductance per Cell for a Travelling Wave Kicker Magnet (2007)

Barnes And, M. J. Barnes, G. D. Wait

Many present day kicker magnets must have a relatively short field rise time, and low flat-top and postpulse ripple. In order to design the electrical circuit for a kicker magnet with the required...

An Improved Beam Screen for the LHC Injection Kickers (2007)

Barnes, M J, Caspers, F, Ducimetière, L, Garrel, N, Kroyer, T

The two LHC injection kicker magnet systems must produce a kick of 1.3 T.m with a flattop duration variable up to 7860 ns, and rise and fall times of less than 900 ns and 3000 ns, respectively. Each...

Design of the Modulator the CTF3 Tail Clipper Kicker (2007)

Barnes, M J, Fowler, T, Ravida, G, Ueda, A

The goal of the present CLIC Test Facility (CTF3) is to demonstrate the technical feasibility of specific key issues in the CLIC scheme. The extracted beam from the combiner ring (CR), of 35 A in...

Improved Measurement of the Positive Muon Lifetime and Determination of the Fermi Constant (2007)

Banks, T. I., Barnes, M. J., Battu, S., Carey, R. M., Cheekatmalla, S., ...

The mean life of the positive muon has been measured to a precision of 11 ppm using a low-energy, pulsed muon beam stopped in a ferromagnetic target, which was surrounded by a scintillator detector...

The LHC injection kicker magnet (2003)

Ducimetière, Laurent, Garrel, N, Barnes, M J, Wait, G D

Proton beams will be injected into LHC at 450 GeV by two kicker magnet systems, producing magnetic field pulses of approximately 900 ns rise time and up to 7.86 s flat top duration. One of...

3 Dimensional Field Calculations compared to Magnetic Measurements for CERN PSB-CPS Transfer Line Magnets (1999)

Barnes, M J, Clark, G S, Sassowsky, M

The transfer line PSB*CPS recombines the four beams from the CERN PS Booster (PSB) in to one beam, which is injected into the CERN 26 GeV Proton Synchrotron (CPS). As part of the ``PS conversion for...

3 Dimensional Field Calculations compared to Magnetic Measurements for CERN PSB-CPS Transfer Line Magnets (1999)

Barnes, M J, Clark, G S, Sassowsky, M

The transfer line PSB*CPS recombines the four beams from the CERN PS Booster (PSB) in to one beam, which is injected into the CERN 26 GeV Proton Synchrotron (CPS). As part of the ``PS conversion for...

Operation Modes of the Fast 60 kV Resonant Charging Power Supply for the LHC Inflectors (1997)

Barnes, M J, Wait, G D, Carlier, E, Ducimetière, L, Jansson, U, Schröder, G, ...

CERN, the European Laboratory for Particle Physics, is constructing a Large Hadron Collider (LHC) to be installed in the existing LEP tunnel of 27 km circumference. The LHC will accelerate two proton...

Kick Stability Analysis of the LHC Inflectors (1996)

Ducimetière, L, Jansson, U, Schröder, G, Vossenberg, Eugène B, Barnes, M J, Wait, G D

Two sets of four LHC inflector magnet systems must produce a kick of 1.36 Tm each with a duration of 6.5 µs, a rise time of 750 ns, and an overall stability of ± 0.5%. The electrical circuit of the...

Kick Stability Analysis of the LHC Inflectors (1996)

Ducimetière, L, Jansson, U, Schröder, G, Vossenberg, Eugène B, Barnes, M J, Wait, G D

Two sets of four LHC inflector magnet systems must produce a kick of 1.36 Tm each with a duration of 6.5 µs, a rise time of 750 ns, and an overall stability of ± 0.5%. The electrical circuit of the...

Design of the injection kicker magnet system for CERN's 14 TeV proton collider LHC (1995)

Ducimetière, L, Jansson, U, Schröder, G, Vossenberg, Eugène B, Barnes, M J, Wait, G D

Two counter-rotating proton beams will be injected into the LHC at an energy of 450 GeV by two kicker magnet systems, producing magnetic field pulses of approximately 750 ns rise time and 6.6 µs...

Analysis of alpha 1 beta 1, alpha 2 beta 1 and alpha 3 beta 1 integrins in cell--collagen interactions: identification of conformation dependent alpha 1 beta 1 binding sites in collagen type I.

Gullberg, D, Gehlsen, K R, Turner, D C, Ahlén, K, Zijenah, L S, Barnes, M J, ...

Integrins can mediate the attachment of cells to collagen type I. In the present study we have investigated the possible differences in collagen type I recognition sites for the alpha 1 beta 1 and...

Inhibition of human platelet adenylate cyclase by collagen fibres. Effect of collagen is additive with that of adrenaline, but interactive with that of thrombin.

Farndale, R W, Winkler, A B, Martin, B R, Barnes, M J

Collagen fibres in suspension have been shown to inhibit adenylate cyclase in human platelet preparations. Direct inhibition by collagen fibres was observed when intact platelets were used, although...

Platelet adhesion to collagen. Factors affecting Mg2(+)-dependent and bivalent-cation-independent adhesion.

Zijenah, L S, Morton, L F, Barnes, M J

Platelet adhesion to collagens immobilized on plastic has been measured, with the following results. (1) Human, but not rabbit, platelets adhered readily to pepsin-extracted monomeric collagens in an...

Integrin alpha 2 beta 1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for alpha 2 beta 1-independent platelet reactivity.

Morton, L F, Hargreaves, P G, Farndale, R W, Young, R D, Barnes, M J

The platelet reactivities of two simple collagen-like synthetic peptides, Gly-Lys-Hyp-(Gly-Pro-Hyp)10-Gly-Lys-Hyp-Gly and Gly-Cys-Hyp-(Gly-Pro-Hyp)10-Gly-Cys-Hyp-Gly, were investigated. Both peptides...

Conformation-dependent platelet adhesion to collagen involving integrin alpha 2 beta 1-mediated and other mechanisms: multiple alpha 2 beta 1-recognition sites in collagen type I.

Morton, L F, Peachey, A R, Zijenah, L S, Goodall, A H, Humphries, M J, Barnes, M J

Platelet adhesion has been measured to type-I monomeric collagen, collagen fibres, alpha 1(I) and alpha 2(I) chains and the chain fragments alpha 1(I)CB3, alpha 1(I)CB6, alpha 1(I)CB7 and alpha...

Platelet-reactive sites in collagens type I and type III. Evidence for separate adhesion and aggregatory sites.

Morton, L F, Peachey, A R, Barnes, M J

The adhesion of human and rabbit platelets to collagens and collagen-derived fragments immobilized on plastic was investigated. Adhesion appeared to be independent of collagen conformation, since...

Platelet-reactive sites in collagen. Collagens I and III possess different aggregatory sites.

Morton, L F, Fitzsimmons, C M, Rauterberg, J, Barnes, M J

Collagen type III possesses a highly reactive platelet-aggregatory site at a locus which in type I is essentially inactive whilst the latter collagen possesses reactive sites absent in type III. It...

Failure of highly purified lysyl hydroxylase to hydroxylate lysyl residues in the non-helical regions of collagen.

Royce, P M, Barnes, M J

The activity of highly purified lysyl hydroxylase towards lysyl residues within both the helical and the N-terminal non-helical telopeptide regions of chick type I collagen has been examined. The...

Comparison of the collagenous products synthesized in culture by pig aortic endothelial and smooth-muscle cells. Variability in endothelial-cell cultures.

Sankey, E A, Barnes, M J

In contrast with smooth-muscle cells from the same tissue, endothelial cells from pig aorta were found to exhibit in culture considerable variability in the pattern of collagen synthesis between one...

Analysis of the collagen types synthesized by bovine corneal endothelial cells in culture.

Sankey, E A, Bown, F E, Morton, L F, Scott, D M, Barnes, M J

Bovine corneal endothelial cells synthesize in culture predominantly type III collagen, with lesser amounts of types I and V and apparently little if any type IV. This pattern of synthesis is...

Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin.

Murphy, G, Cawston, T E, Galloway, W A, Barnes, M J, Bunning, R A, Mercer, E, ...

Gel-filtration chromatography of culture medium from rabbit bone explants separates three latent metalloproteinases with activities against collagen, proteoglycan and gelatin respectively. The...

Presence of type III collagen in guinea-pig dermal scar.

Barnes, M J, Morton, L F, Bennett, R C, Bailey, A J, Sims, T J

Guinea-pig dermal scar was shown to contain type III collagen, and, from densitometric analysis of gel electrophoretograms, it was shown to have a higher concentration than the surrounding dermis....

Platelet-aggregating activity of type I and type III collagens from human aorta and chicken skin.

Barnes, M J, Gordon, J L, MacIntyre, D E

Human or chicken type III collagen dissolved in 0.1 M-acetic acid was much more potent than type I collagen at inducing platelet aggregation. After incubation in 0.38M-Na2HPO4 to promote...

Age-related variations in hydroxylation of lysine and proline in collagen

Barnes, M. J., Constable, B. J., Morton, L. F., Royce, P. M.

The effect of age on the extent of hydroxylation of lysine and proline both generally and at certain specific sites in collagens from bone, skin and tendon was examined in the chick from the 14-day...

Bone collagen metabolism in vitamin D deficiency (Short Communication)

Barnes, M. J., Constable, B. J., Morton, L. F., Kodicek, E.

Radioisotope studies have shown that collagen synthesized in the shafts of bones from rachitic rats and chicks is similar in chain composition to that normally synthesized. However, the extent of...

Hydroxylysine in the N-terminal regions of the α1- and α2-chains of various collagens

Barnes, M. J., Constable, B. J., Morton, L. F., Kodicek, E.

The degree of hydroxylation of the lysine residue located in both α1- and α2-chains of collagen in the N-terminal, non-helical telopeptide region of the molecule has been determined in collagen...

Studies in vivo on the biosynthesis of collagen and elastin in ascorbic acid-deficient guinea pigs. Evidence for the formation and degradation of a partially hydroxylated collagen

Barnes, M. J., Constable, B. J., Morton, L. F., Kodicek, E.

1. After the administration of l-[G-3H]proline to guinea pigs deprived of ascorbic acid for increasing periods of time, the specific radioactivities of proline and hydroxyproline in skin collagen and...

Studies in vivo on the biosynthesis of collagen and elastin in ascorbic acid-deficient guinea pigs

Barnes, M. J., Constable, B. J., Kodicek, E.

1. After the administration of labelled proline to guinea pigs deprived of ascorbic acid for 15 days, the dorsal skin was examined 5 days later in an attempt to detect the presence of...

The isolation and characterization of a glycoprotein from human thoracic aorta

Barnes, M. J., Partridge, S. M.

1. A glycoprotein extracted by cold alkali from the walls of human aorta was purified by chromatography on DEAE-cellulose. 2. The compound was electrophoretically homogeneous and essentially so by...

Monomeric (glycine-proline-hydroxyproline)10 repeat sequence is a partial agonist of the platelet collagen receptor glycoprotein VI.

Asselin, J, Knight, C G, Farndale, R W, Barnes, M J, Watson, S P

We have previously reported that a triple-helical, collagen-related peptide (CRP; also known as CRP-XL) containing a glycine-proline-hydroxyproline (GPP*) repeat motif and cross-linked through...

Monoclonal antibodies identify residues 199-216 of the integrin alpha2 vWFA domain as a functionally important region within alpha2beta1.

Tuckwell, D S, Smith, L, Korda, M, Askari, J A, Santoso, S, Barnes, M J, ...

Integrin alpha2beta1 is the major receptor for collagens in the human body, and the collagen-binding site on the alpha2 subunit von Willebrand factor A-type domain (vWFA domain) is now well defined....

Analysis of alpha 1 beta 1, alpha 2 beta 1 and alpha 3 beta 1 integrins in cell--collagen interactions: identification of conformation dependent alpha 1 beta 1 binding sites in collagen type I.

Gullberg, D, Gehlsen, K R, Turner, D C, Ahlén, K, Zijenah, L S, Barnes, M J, ...

Integrins can mediate the attachment of cells to collagen type I. In the present study we have investigated the possible differences in collagen type I recognition sites for the alpha 1 beta 1 and...

Inhibition of human platelet adenylate cyclase by collagen fibres. Effect of collagen is additive with that of adrenaline, but interactive with that of thrombin.

Farndale, R W, Winkler, A B, Martin, B R, Barnes, M J

Collagen fibres in suspension have been shown to inhibit adenylate cyclase in human platelet preparations. Direct inhibition by collagen fibres was observed when intact platelets were used, although...

Platelet adhesion to collagen. Factors affecting Mg2(+)-dependent and bivalent-cation-independent adhesion.

Zijenah, L S, Morton, L F, Barnes, M J

Platelet adhesion to collagens immobilized on plastic has been measured, with the following results. (1) Human, but not rabbit, platelets adhered readily to pepsin-extracted monomeric collagens in an...

Integrin alpha 2 beta 1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for alpha 2 beta 1-independent platelet reactivity.

Morton, L F, Hargreaves, P G, Farndale, R W, Young, R D, Barnes, M J

The platelet reactivities of two simple collagen-like synthetic peptides, Gly-Lys-Hyp-(Gly-Pro-Hyp)10-Gly-Lys-Hyp-Gly and Gly-Cys-Hyp-(Gly-Pro-Hyp)10-Gly-Cys-Hyp-Gly, were investigated. Both peptides...

Conformation-dependent platelet adhesion to collagen involving integrin alpha 2 beta 1-mediated and other mechanisms: multiple alpha 2 beta 1-recognition sites in collagen type I.

Morton, L F, Peachey, A R, Zijenah, L S, Goodall, A H, Humphries, M J, Barnes, M J

Platelet adhesion has been measured to type-I monomeric collagen, collagen fibres, alpha 1(I) and alpha 2(I) chains and the chain fragments alpha 1(I)CB3, alpha 1(I)CB6, alpha 1(I)CB7 and alpha...

Platelet-reactive sites in collagens type I and type III. Evidence for separate adhesion and aggregatory sites.

Morton, L F, Peachey, A R, Barnes, M J

The adhesion of human and rabbit platelets to collagens and collagen-derived fragments immobilized on plastic was investigated. Adhesion appeared to be independent of collagen conformation, since...

Platelet-reactive sites in collagen. Collagens I and III possess different aggregatory sites.

Morton, L F, Fitzsimmons, C M, Rauterberg, J, Barnes, M J

Collagen type III possesses a highly reactive platelet-aggregatory site at a locus which in type I is essentially inactive whilst the latter collagen possesses reactive sites absent in type III. It...

Failure of highly purified lysyl hydroxylase to hydroxylate lysyl residues in the non-helical regions of collagen.

Royce, P M, Barnes, M J

The activity of highly purified lysyl hydroxylase towards lysyl residues within both the helical and the N-terminal non-helical telopeptide regions of chick type I collagen has been examined. The...

Comparison of the collagenous products synthesized in culture by pig aortic endothelial and smooth-muscle cells. Variability in endothelial-cell cultures.

Sankey, E A, Barnes, M J

In contrast with smooth-muscle cells from the same tissue, endothelial cells from pig aorta were found to exhibit in culture considerable variability in the pattern of collagen synthesis between one...

Analysis of the collagen types synthesized by bovine corneal endothelial cells in culture.

Sankey, E A, Bown, F E, Morton, L F, Scott, D M, Barnes, M J

Bovine corneal endothelial cells synthesize in culture predominantly type III collagen, with lesser amounts of types I and V and apparently little if any type IV. This pattern of synthesis is...

Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin.

Murphy, G, Cawston, T E, Galloway, W A, Barnes, M J, Bunning, R A, Mercer, E, ...

Gel-filtration chromatography of culture medium from rabbit bone explants separates three latent metalloproteinases with activities against collagen, proteoglycan and gelatin respectively. The...

Presence of type III collagen in guinea-pig dermal scar.

Barnes, M J, Morton, L F, Bennett, R C, Bailey, A J, Sims, T J

Guinea-pig dermal scar was shown to contain type III collagen, and, from densitometric analysis of gel electrophoretograms, it was shown to have a higher concentration than the surrounding dermis....

Platelet-aggregating activity of type I and type III collagens from human aorta and chicken skin.

Barnes, M J, Gordon, J L, MacIntyre, D E

Human or chicken type III collagen dissolved in 0.1 M-acetic acid was much more potent than type I collagen at inducing platelet aggregation. After incubation in 0.38M-Na2HPO4 to promote...

Age-related variations in hydroxylation of lysine and proline in collagen

Barnes, M. J., Constable, B. J., Morton, L. F., Royce, P. M.

The effect of age on the extent of hydroxylation of lysine and proline both generally and at certain specific sites in collagens from bone, skin and tendon was examined in the chick from the 14-day...

Bone collagen metabolism in vitamin D deficiency (Short Communication)

Barnes, M. J., Constable, B. J., Morton, L. F., Kodicek, E.

Radioisotope studies have shown that collagen synthesized in the shafts of bones from rachitic rats and chicks is similar in chain composition to that normally synthesized. However, the extent of...

Hydroxylysine in the N-terminal regions of the α1- and α2-chains of various collagens

Barnes, M. J., Constable, B. J., Morton, L. F., Kodicek, E.

The degree of hydroxylation of the lysine residue located in both α1- and α2-chains of collagen in the N-terminal, non-helical telopeptide region of the molecule has been determined in collagen...

Studies in vivo on the biosynthesis of collagen and elastin in ascorbic acid-deficient guinea pigs. Evidence for the formation and degradation of a partially hydroxylated collagen

Barnes, M. J., Constable, B. J., Morton, L. F., Kodicek, E.

1. After the administration of l-[G-3H]proline to guinea pigs deprived of ascorbic acid for increasing periods of time, the specific radioactivities of proline and hydroxyproline in skin collagen and...

Studies in vivo on the biosynthesis of collagen and elastin in ascorbic acid-deficient guinea pigs

Barnes, M. J., Constable, B. J., Kodicek, E.

1. After the administration of labelled proline to guinea pigs deprived of ascorbic acid for 15 days, the dorsal skin was examined 5 days later in an attempt to detect the presence of...

The isolation and characterization of a glycoprotein from human thoracic aorta

Barnes, M. J., Partridge, S. M.

1. A glycoprotein extracted by cold alkali from the walls of human aorta was purified by chromatography on DEAE-cellulose. 2. The compound was electrophoretically homogeneous and essentially so by...

Monomeric (glycine-proline-hydroxyproline)10 repeat sequence is a partial agonist of the platelet collagen receptor glycoprotein VI.

Asselin, J, Knight, C G, Farndale, R W, Barnes, M J, Watson, S P

We have previously reported that a triple-helical, collagen-related peptide (CRP; also known as CRP-XL) containing a glycine-proline-hydroxyproline (GPP*) repeat motif and cross-linked through...

Monoclonal antibodies identify residues 199-216 of the integrin alpha2 vWFA domain as a functionally important region within alpha2beta1.

Tuckwell, D S, Smith, L, Korda, M, Askari, J A, Santoso, S, Barnes, M J, ...

Integrin alpha2beta1 is the major receptor for collagens in the human body, and the collagen-binding site on the alpha2 subunit von Willebrand factor A-type domain (vWFA domain) is now well defined....

Kick Stability Analysis of the LHC Inflectors

Barnes And Wait, M. J. Barnes, G. D. Wait

Two sets of four LHC inflector magnet systems must produce a kick of 1.36 Tm each with a duration of 6.5 ¯s, a rise time of 750 ns, and an overall stability of \Sigma0.5 %. The electrical circuit of...