M. J. Cannon

Comparative analyses of a small molecule/enzyme interaction by multiple users of Biacore technology (2004)

Cannon, M.J., Papalia, G.A., Navratilova, I., Fisher, R.J., Roberts, L.R., Worthy, K.M., ...

To gauge the experimental variability associated with Biacore analysis, 36 different investigators analyzed a small molecule/enzyme interaction under similar conditions. Acetazolamide (222 g/mol)...

In vivo growth of Epstein-Barr virus transformed B cells with mutations in latent membrane protein 2 (LMP2) (1997)

Izumi, K. M., Rochford, R., Kieff, E., Cannon, M. J., Miller, C. L., Longnecker, R.

 Epstein-Barr virus (EBV) causes infectious mononucleosis in adolescents and is associated with malignant B lymphocyte proliferation in AIDS patients, patients undergoing immune suppression for...

Plasmacytoid differentiation of Epstein-Barr virus-transformed B cells in vivo is associated with reduced expression of viral latent genes.

Rochford, R, Hobbs, M V, Garnier, J L, Cooper, N R, Cannon, M J

The Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorders that arise in immunosuppressed individuals are considered to resemble EBV-transformed in vitro lymphoblastoid cell lines...

Inhibition of Epstein-Barr virus infection in vitro and in vivo by soluble CR2 (CD21) containing two short consensus repeats.

Moore, M D, Cannon, M J, Sewall, A, Finlayson, M, Okimoto, M, Nemerow, G R

The extracellular domain of CR2, the Epstein-Barr virus (EBV)/C3d receptor of B lymphocytes, contains 15 or 16 tandemly arranged short consensus repeat elements (SCR). Recombinant CR2 proteins...

Cytotoxic T-cell response to respiratory syncytial virus in mice.

Bangham, C R, Cannon, M J, Karzon, D T, Askonas, B A

The role of the humoral and cellular arms of the immune response in protection against respiratory syncytial virus (RSV) infection and in the pathogenesis of the severe forms of this disease is...

Epstein-Barr virus induces aggressive lymphoproliferative disorders of human B cell origin in SCID/hu chimeric mice.

Cannon, M J, Pisa, P, Fox, R I, Cooper, N R

C.B-17 scid mice were reconstituted by intraperitoneal injection of human tonsil cells or PBL from EBV-seronegative donors. Subsequent injection of EBV resulted in the rapid development (within 19-33...

Plasmacytoid differentiation of Epstein-Barr virus-transformed B cells in vivo is associated with reduced expression of viral latent genes.

Rochford, R, Hobbs, M V, Garnier, J L, Cooper, N R, Cannon, M J

The Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorders that arise in immunosuppressed individuals are considered to resemble EBV-transformed in vitro lymphoblastoid cell lines...

Inhibition of Epstein-Barr virus infection in vitro and in vivo by soluble CR2 (CD21) containing two short consensus repeats.

Moore, M D, Cannon, M J, Sewall, A, Finlayson, M, Okimoto, M, Nemerow, G R

The extracellular domain of CR2, the Epstein-Barr virus (EBV)/C3d receptor of B lymphocytes, contains 15 or 16 tandemly arranged short consensus repeat elements (SCR). Recombinant CR2 proteins...

Cytotoxic T-cell response to respiratory syncytial virus in mice.

Bangham, C R, Cannon, M J, Karzon, D T, Askonas, B A

The role of the humoral and cellular arms of the immune response in protection against respiratory syncytial virus (RSV) infection and in the pathogenesis of the severe forms of this disease is...

Epstein-Barr virus induces aggressive lymphoproliferative disorders of human B cell origin in SCID/hu chimeric mice.

Cannon, M J, Pisa, P, Fox, R I, Cooper, N R

C.B-17 scid mice were reconstituted by intraperitoneal injection of human tonsil cells or PBL from EBV-seronegative donors. Subsequent injection of EBV resulted in the rapid development (within 19-33...

Clearance of persistent respiratory syncytial virus infections in immunodeficient mice following transfer of primed T cells.

Cannon, M J, Stott, E J, Taylor, G, Askonas, B A

Little is known of the role of T-cell mediated immune responses in the clearance and pathogenesis of respiratory syncytial virus (RSV) infection. In this study, we established persistent pulmonary...

Low expression of CD20 and CD23 in Epstein-Barr virus-induced B cell tumors in SCID/hu mice.

Garnier, J. L., Cooper, N. R., Cannon, M. J.

Intraperitoneal injection of immunodeficient C.B.-17/scid (SCID) mice with human peripheral blood leukocytes from Epstein-Barr virus (EBV)-seropositive donors or with peripheral blood leukocytes from...