Identification of EFHC2 as a quantitative trait locus for fear recognition in Turner syndrome (2006)
Weiss, L.A., Purcell, S., Waggoner, S., Lawrence, K., Spektor, D., Daly, M.J., ...
One-third of women with Turner syndrome (45,X) have autism-like social and communication difficulties, despite normal verbal IQ. Deletion mapping of the X-chromosome implicated 5 Mb of Xp11.3–4 as...
Lindgren, C M, Mahtani, M M, Widén, E, McCarthy, M I, Daly, M J, Kirby, A, ...
Abstract is not available
Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses.
Gorham, J D, Güler, M L, Steen, R G, Mackey, A J, Daly, M J, Frederick, K, ...
Genetic background of the T cell can influence T helper (Th) phenotype development, with some murine strains (e.g., B10.D2) favoring Th1 development and others (e.g., BALB/c) favoring Th2...
Reduction of Fe(III), Cr(VI), U(VI), and Tc(VII) by Deinococcus radiodurans R1
Fredrickson, J. K., Kostandarithes, H. M., Li, S. W., Plymale, A. E., Daly, M. J.
Deinococcus radiodurans is an exceptionally radiation-resistant microorganism capable of surviving acute exposures to ionizing radiation doses of 15,000 Gy and previously described as having a...
Interchromosomal recombination in the extremely radioresistant bacterium Deinococcus radiodurans.
Deinococcus radiodurans and other members of the genus Deinococcus are remarkable for their extreme resistance to ionizing radiation and many other agents that damage DNA. We have recently shown that...
Expression of recA in Deinococcus radiodurans.
Carroll, J D, Daly, M J, Minton, K W
Deinococcus (formerly Micrococcus) radiodurans is remarkable for its extraordinary resistance to ionizing and UV irradiation and many other agents that damage DNA. This organism can repair > 100...
Deinococcus radiodurans R1 and other members of this genus are able to repair and survive extreme DNA damage induced by ionizing radiation and many other DNA-damaging agents. The ability of R1 to...
Daly, M J, Ling, O, Minton, K W
Deinococcus radiodurans R1 and other members of the eubacterial family Deinococcaceae are extremely resistant to ionizing radiation and many other agents that damage DNA. For example, after...
Daly, M J, Ouyang, L, Fuchs, P, Minton, K W
Deinococcus radiodurans R1 and other members of this genus share extraordinary resistance to the lethal and mutagenic effects of ionizing radiation. We have recently identified a RecA homolog in...
Acheiropodia Is Caused by a Genomic Deletion in C7orf2, the Human Orthologue of the Lmbr1 Gene
Ianakiev, P., Van Baren, M. J., Daly, M. J., Toledo, S. P. A., Cavalcanti, M. G., Neto, J. Correa, ...
Acheiropodia is an autosomal recessive developmental disorder presenting with bilateral congenital amputations of the upper and lower extremities and aplasia of the hands and feet. This severely...
Genomewide scan of multiple sclerosis in Finnish multiplex families.
Kuokkanen, S, Gschwend, M, Rioux, J D, Daly, M J, Terwilliger, J D, Tienari, P J, ...
Multiple sclerosis (MS) is a neurological, demyelinating disorder with a putative autoimmune etiology. It is thought to be a multifactorial disease with a complex mode of inheritance. Here we report...
Familial eosinophilia maps to the cytokine gene cluster on human chromosomal region 5q31-q33.
Rioux, J D, Stone, V A, Daly, M J, Cargill, M, Green, T, Nguyen, H, ...
Familial eosinophilia (FE) is an autosomal dominant disorder characterized by peripheral hypereosinophilia of unidentifiable cause with or without other organ involvement. To localize the gene for...
Gaudet, D, Arsenault, S, Pérusse, L, Vohl, M C, St-Pierre, J, Bergeron, J, ...
Glycerol kinase (GK) represents the primary entry of glycerol into glucose and triglyceride metabolism. Impaired glucose tolerance (IGT) and hypertriglyceridemia are associated with an increased risk...
Rioux, J D, Silverberg, M S, Daly, M J, Steinhart, A H, McLeod, R S, Griffiths, A M, ...
The chronic inflammatory bowel diseases (IBDs)-Crohn disease (CD) and ulcerative colitis (UC)-are idiopathic, inflammatory disorders of the gastrointestinal tract. These conditions have a peak...
Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses.
Gorham, J D, Güler, M L, Steen, R G, Mackey, A J, Daly, M J, Frederick, K, ...
Genetic background of the T cell can influence T helper (Th) phenotype development, with some murine strains (e.g., B10.D2) favoring Th1 development and others (e.g., BALB/c) favoring Th2...
Reduction of Fe(III), Cr(VI), U(VI), and Tc(VII) by Deinococcus radiodurans R1
Fredrickson, J. K., Kostandarithes, H. M., Li, S. W., Plymale, A. E., Daly, M. J.
Deinococcus radiodurans is an exceptionally radiation-resistant microorganism capable of surviving acute exposures to ionizing radiation doses of 15,000 Gy and previously described as having a...
Interchromosomal recombination in the extremely radioresistant bacterium Deinococcus radiodurans.
Deinococcus radiodurans and other members of the genus Deinococcus are remarkable for their extreme resistance to ionizing radiation and many other agents that damage DNA. We have recently shown that...
Expression of recA in Deinococcus radiodurans.
Carroll, J D, Daly, M J, Minton, K W
Deinococcus (formerly Micrococcus) radiodurans is remarkable for its extraordinary resistance to ionizing and UV irradiation and many other agents that damage DNA. This organism can repair > 100...
Deinococcus radiodurans R1 and other members of this genus are able to repair and survive extreme DNA damage induced by ionizing radiation and many other DNA-damaging agents. The ability of R1 to...
Daly, M J, Ling, O, Minton, K W
Deinococcus radiodurans R1 and other members of the eubacterial family Deinococcaceae are extremely resistant to ionizing radiation and many other agents that damage DNA. For example, after...
Daly, M J, Ouyang, L, Fuchs, P, Minton, K W
Deinococcus radiodurans R1 and other members of this genus share extraordinary resistance to the lethal and mutagenic effects of ionizing radiation. We have recently identified a RecA homolog in...
Lindgren, C. M., Mahtani, M. M., Widén, E., McCarthy, M. I., Daly, M. J., Kirby, A., ...
Type 2 diabetes mellitus is a heterogeneous inherited disorder characterized by chronic hyperglycemia resulting from pancreatic β-cell dysfunction and insulin resistance. Although the pathogenic...
Middleton, F. A., Pato, M. T., Gentile, K. L., Morley, C. P., Zhao, X., Eisener, A. F., ...
We performed a linkage analysis on 25 extended multiplex Portuguese families segregating for bipolar disorder, by use of a high-density single-nucleotide–polymorphism (SNP) genotyping assay, the...
Acheiropodia Is Caused by a Genomic Deletion in C7orf2, the Human Orthologue of the Lmbr1 Gene
Ianakiev, P., Van Baren, M. J., Daly, M. J., Toledo, S. P. A., Cavalcanti, M. G., Neto, J. Correa, ...
Acheiropodia is an autosomal recessive developmental disorder presenting with bilateral congenital amputations of the upper and lower extremities and aplasia of the hands and feet. This severely...
Familial eosinophilia maps to the cytokine gene cluster on human chromosomal region 5q31-q33.
Rioux, J D, Stone, V A, Daly, M J, Cargill, M, Green, T, Nguyen, H, ...
Familial eosinophilia (FE) is an autosomal dominant disorder characterized by peripheral hypereosinophilia of unidentifiable cause with or without other organ involvement. To localize the gene for...
Gaudet, D, Arsenault, S, Pérusse, L, Vohl, M C, St-Pierre, J, Bergeron, J, ...
Glycerol kinase (GK) represents the primary entry of glycerol into glucose and triglyceride metabolism. Impaired glucose tolerance (IGT) and hypertriglyceridemia are associated with an increased risk...
Rioux, J D, Silverberg, M S, Daly, M J, Steinhart, A H, McLeod, R S, Griffiths, A M, ...
The chronic inflammatory bowel diseases (IBDs)-Crohn disease (CD) and ulcerative colitis (UC)-are idiopathic, inflammatory disorders of the gastrointestinal tract. These conditions have a peak...
Genomewide scan of multiple sclerosis in Finnish multiplex families.
Kuokkanen, S, Gschwend, M, Rioux, J D, Daly, M J, Terwilliger, J D, Tienari, P J, ...
Multiple sclerosis (MS) is a neurological, demyelinating disorder with a putative autoimmune etiology. It is thought to be a multifactorial disease with a complex mode of inheritance. Here we report...
Kruglyak, L, Daly, M J, Lander, E S
Homozygosity mapping is a powerful strategy for mapping rare recessive traits in children of consanguineous marriages. Practical applications of this strategy are currently limited by the inability...
Bardhan, K D, Morris, P, Thompson, M, Dhande, D S, Hinchliffe, R F, Jones, R B, ...
Forty five patients with refractory oesophagitis, defined as persisting erosive changes or ulceration despite a minimum of three months' treatment with cimetidine 3.2 g daily or ranitidine 0.9 g...
Bardhan, K D, Naesdal, J, Bianchi Porro, G, Petrillo, M, Lazzaroni, M, Hinchliffe, R F, ...
We tested the hypothesis that the gastric H+/K+ adenosine triphosphatase inhibitor, omeprazole, because of its different mode of action and pronounced inhibitory effect on gastric acid secretion, may...
Daly, M J, Humphray, J M, Stables, R
The new H2-receptor antagonist, ranitidine, has been compared with cimetidine and metiamide as an inhibitor of gastric acid secretion in the dog. All three compounds were effective both intravenously...
Parametric and nonparametric linkage analysis: a unified multipoint approach.
Kruglyak, L., Daly, M. J., Reeve-Daly, M. P., Lander, E. S.
In complex disease studies, it is crucial to perform multipoint linkage analysis with many markers and to use robust nonparametric methods that take account of all pedigree information. Currently...
Daly, M. J., Farmer, J. B., Levy, G. P.
1. Bronchodilator and cardiovascular actions of salbutamol and isoprenaline have been compared in guinea-pigs and dogs. Orciprenaline was also included in some experiments.
Daly, M J, Flook, J J, Levy, G P
1 The actions of five beta-adrenoceptor antagonists, chosen because of reported differences in their selectivities, were compared using the positive chronotropic, vasodepressor and bronchodilator...
Apperley, G H, Daly, M J, Levy, G P
1 The potencies of fifteen beta-adrenoceptor agonists of widely differing chemical structures were compared with that of (-)-isoprenaline on bronchial muscle, soleus muscle, blood pressure and heart...
The effect of (-)-isoprenaline and (+/-)-salbutamol on pepsinogen and acid secretion in the dog.
1 The beta-adrenoceptor agonists, (-)-isoprenaline and (+/-)-salbutamol, reduced pepsinogen secretion induced by pentagastrin in conscious dogs with Heidenhaim pouches. 2 (-)-Isoprenaline and...
The role of beta1- and beta2-adrenoceptors in the inhibition of gastric acid secretion in the dog.
Daly, M J, Long, J M, Stables, R
1. Characterization of the beta-adrenoceptors mediating inhibition of gastric acid secretion in the conscious Heidenhain pouch dog has been investigated by determination of the effects of...
Taloximine, a new respiratory stimulant with bronchodilator properties
Daly, M. J., Lightowler, J. E., Pickering, R. W.
1. A novel phthalazine analogue taloximine (1-hydroxyimino-4(2-dimethyl-aminoethoxy)-1,2-dihydrophthalazine monohydrochloride monohydrate) stimulated respiration in conscious rabbits at doses of 7...
In the anaesthetized guinea-pig micro-embolism induced by barium sulphate causes marked increases in pulmonary resistance and decreases in pulmonary compliance. Bronchodilator drugs prevent these...
Ranitidine (AH 19065): a new potent, selective histamine H2-receptor antagonist [proceedings]
Bradshaw, J., Brittain, R. T., Clitherow, J. W., Daly, M. J., Jack, D., Price, B. J., ...
Some in vitro and in vivo actions of the new histamine H2-receptor antagonist, ranitidine.
Daly, M. J., Humphray, J. M., Stables, R.
1 Ranitidine has been investigated as an antagonist of the H2-receptor-mediated responses to histamine of guniea-pig atrium and rat uterus in vitro and as an inhibitor of gastric acid secretion in...
Daly, M. J., Humphray, J. M., Stables, R.
1 The new H2-receptor antagonist, ranitidine, has been compared with cimetidine as an inhibitor of gastric acid secretion in the anaesthetized dog. 2 Both ranitidine and cimetidine given...
Daly, M. J., Humphray, J. M., Stables, R.
1 The H2-receptor antagonists, ranitidine and cimetidine, have been compared with atropine and pirenzepine for their effects on gastric acid output, and on salivary secretion from the left parotid...