Human Proteinpedia enables sharing of human protein data (2008)
Mathivanan, S., Ahmed, M., Ahn, N. G., Alexandre, H., Amanchy, R., Andrews, P. C., ...
Lifted Turbulent Premixed Flames Issuing Into a Hot Coflow, Imaging of Temperature and OH (2007)
Dunn, M. J., Masri, A. R., Bilger, R. W., Jacobs, Peter, McIntyre, Tim, Cleary, Matthew, ...
The experimental results of simultaneous 2D laser Rayleigh scattering and OH Planar Laser Induced Fluorescence (PLIF) imaging applied to lifted turbulent premixed flames issuing into a hot coflow are...
The minimum information about a proteomics experiment (MIAPE) (2007)
Taylor, C. F., Paton, N. W., Lilley, K. S., Binz, P. A., Julian, R. K., Jones, A. R., ...
The minimum information about a proteomics experiment (MIAPE) (2007)
Taylor, C.F., Paton, N.W., Lilley, K.S., Binz, P-A, Julian, R.K., Jones, A.R., ...
Both the generation and the analysis of proteomics data are now widespread, and high-throughput approaches are commonplace. Protocols continue to increase in complexity as methods and technologies...
Lifted Turbulent Premixed Flames Issuing Into a Hot Coflow, Imaging of Temperature and OH (2007)
Dunn, M. J., Masri, A. R., Bilger, R. W.
The experimental results of simultaneous 2D laser Rayleigh scattering and OH Planar Laser Induced Fluorescence (PLIF) imaging applied to lifted turbulent premixed flames issuing into a hot coflow are...
Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice (2004)
Mayr,M., Metzler,B., Chung,Y. L., McGregor,E., Mayr,U., Troy,H., ...
Ischemic preconditioning confers cardiac protection during subsequent ischemia-reperfusion, in which protein kinase C (PKC) is believed to play an essential role, but controversial data exist...
Loss of PKC-delta alters cardiac metabolism (2004)
Mayr,M., Chung,Y. L., Mayr,U., McGregor,E., Troy,H., Baier,G., ...
PKC-delta is believed to play an essential role in cardiomyocyte growth. In the present study, we investigated the effect of PKC-delta on cardiac metabolism using PKC-delta knockout mice generated in...
Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice (2004)
Mayr, M., Metzler, B., Chung, Y. L., McGregor, E., Mayr, U., Troy, H., ...
Ischemic preconditioning confers cardiac protection during subsequent ischemia-reperfusion, in which protein kinase C (PKC) is believed to play an essential role, but controversial data exist...
Loss of PKC-delta alters cardiac metabolism (2004)
Mayr, M., Chung, Y. L., Mayr, U., McGregor, E., Troy, H., Baier, G., ...
PKC-delta is believed to play an essential role in cardiomyocyte growth. In the present study, we investigated the effect of PKC-delta on cardiac metabolism using PKC-delta knockout mice generated in...
Loss of PKC-delta alters cardiac metabolism (2004)
Mayr, M., Chung, Y. L., Mayr, U., McGregor, E., Troy, H., Baier, G., ...
PKC-delta is believed to play an essential role in cardiomyocyte growth. In the present study, we investigated the effect of PKC-delta on cardiac metabolism using PKC-delta knockout mice generated in...
Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice (2004)
Mayr, M., Metzler, B., Chung, Y. L., McGregor, E., Mayr, U., Troy, H., ...
Ischemic preconditioning confers cardiac protection during subsequent ischemia-reperfusion, in which protein kinase C (PKC) is believed to play an essential role, but controversial data exist...
Differential protein expression at the stage of neural tube closure in the mouse embryo (2002)
Greene, N.D.E., Wait, R., Begum, S., Dunn, M.J., Copp, A.J.
Analysis of the protein complement of a biological system through proteomics provides the opportunity to directly monitor the functional readout of gene expression. In this study, proteomics was...
Alcohol and the heart in humans and animal models (2001)
Dunn, M. J., Patel, V. B., Preedy, V. R., Richardson, P., Worrall, S.
Typescript (photocopy).
Full scale testing of fire suppression agents on unshielded fires / (1998)
Thesis (M. Engr.)--University of Cantebury.
Thomas, C P, Dunn, M J, Mattera, R
The human leukaemic cell line K562 is a pluripotent stem cell with the potential to mature along a megakaryocytic or erythroid line. In these cells, thrombin and U46619 (9,11-dideoxy-9 alpha, 11...
Wang, Y, Simonson, M S, Pouyss Gur, J, Dunn, M J
Mitogen-activated protein (MAP) kinases are regarded as switch kinases in the phosphorylation cascade initiated by various agonists. We have investigated whether endothelins (ET), which are...
The newly isolated peptide, endothelin-1 (ET-1), is a potent pressor agent that reduces GFR and the glomerular ultrafiltration coefficient. Recent evidence demonstrates that ET-1 mobilizes...
Simonson, M S, Wann, S, Men , P, Dubyak, G R, Kester, M, Nakazato, Y, ...
A recently described peptide hormone, endothelin, is a potent vasoconstrictor, but it is unclear whether endothelin has other biological actions. These experiments extend the range of biological...
The newly isolated peptide, endothelin-1 (ET-1), is a potent pressor agent that reduces GFR and the glomerular ultrafiltration coefficient. Recent evidence demonstrates that ET-1 mobilizes...
Simonson, M S, Wann, S, Mené, P, Dubyak, G R, Kester, M, Nakazato, Y, ...
A recently described peptide hormone, endothelin, is a potent vasoconstrictor, but it is unclear whether endothelin has other biological actions. These experiments extend the range of biological...
The nucleotide sequence of a glutamine tRNA from rat liver.
Chan, J C, Yang, J A, Dunn, M J, Agris, P F, Wong, T W
A glutamate tRNA from rat liver was purified. By means of post-labeling techniques, its nucleotide sequence was shown to be: pU-C-C-C-A-C-A-U-m1G-G-U-C-psi-A-G-C-...
The nucleotide sequence of a glutamate tRNA from rat liver.
Chan, J C, Yang, J A, Dunn, M J, Agris, P F, Wong, T W
A glutamate tRNA from rat liver was purified. By means of post-labeling techniques, its nucleotide sequence was shown to be: pU-C-C-C-A-C-A-U-m1G-G-U-C-psi-A-G-C-...
Renal prostaglandin synthesis in the spontaneously hypertensive rat.
The precise role of the kidney in spontaneous experimental hypertension is unknown. We have analyzed the rates of renal prostaglandin synthesis by utilizing a spontaneously hypertensive rat model....
In vivo effect of indomethacin to potentiate the renal medullary cyclic AMP response to vasopressin.
Lum, G M, Aisenbrey, G A, Dunn, M J, Berl, T, Schrier, R W, McDonald, K M
In a previous study we demonstrated that indomethacin potentiated the hydro-osmotic action of vasopressin in vivo. It was hypothesized that this action of indomethacin was due to its ability to...
Monoclonal antibodies detect a spectrin-like protein in normal and dystrophic human skeletal muscle.
Appleyard, S T, Dunn, M J, Dubowitz, V, Scott, M L, Pittman, S J, Shotton, D M
Spectrin is the major protein of the erythrocyte membrane skeleton, which is bound to the cytoplasmic surface of the membrane's lipid bilayer and is responsible for cell shape and membrane...
Arginine vasopressin (AVP) and angiotensin II (ANG II) reduce the glomerular filtration rate and ultrafiltration coefficient. Vasodilatory prostaglandins (PG) antagonize these effects. AVP and ANG II...
Lianos, E A, Andres, G A, Dunn, M J
Glomerular arachidonate cyclooxygenation by isolated rat glomeruli was assessed in vitro in antiglomerular basement membrane (anti-GBM) antibody-induced glomerulonephritis by radioimmunoassay for...
Prostaglandin synthesis in isolated rat kidney glomeruli.
Hassid, A, Konieczkowski, M, Dunn, M J
Isolated rat kidney glomeruli converted octatritiated arachidonic acid to several prostaglandins whose production was inhibited by meclofenamate. These were, in order of decreasing abundance,...
Glomerular arachidonate lipoxygenation in rat nephrotoxic serum nephritis.
Lianos, E A, Rahman, M A, Dunn, M J
Arachidonate lipoxygenation to monohydroxylated eicosatetraenoic acids (HETE) was studied in rat nephrotoxic serum nephritis (NSN). A single infusion of nephrotoxic serum enhanced conversion of...
Increased leukotriene B4 synthesis in immune injured rat glomeruli.
Rahman, M A, Nakazawa, M, Emancipator, S N, Dunn, M J
We examined glomerular synthesis of the 5-lipoxygenase metabolite, LTB4, in normal and immune-injured rat glomeruli. Glomeruli isolated from normal rats and from rats with nephrotoxic serum nephritis...
Activation of extracellular signal-regulated kinase in proliferative glomerulonephritis in rats.
Bokemeyer, D, Guglielmi, K E, McGinty, A, Sorokin, A, Lianos, E A, Dunn, M J
Multiple extracellular mitogens are involved in the pathogenesis of proliferative forms of glomerulonephritis (GN). In vitro studies demonstrate the pivotal role of extracellular signal-regulated...
Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells.
Wang, Y, Simonson, M S, Pouysségur, J, Dunn, M J
Mitogen-activated protein (MAP) kinases are regarded as switch kinases in the phosphorylation cascade initiated by various agonists. We have investigated whether endothelins (ET), which are...
Thomas, C P, Dunn, M J, Mattera, R
The human leukaemic cell line K562 is a pluripotent stem cell with the potential to mature along a megakaryocytic or erythroid line. In these cells, thrombin and U46619 (9,11-dideoxy-9 alpha, 11...
Dunn, M J, Burghes, A H, Dubowitz, V
The Ca2+-stimulated Mg2-dependent ATPase activities (Ca2+-ATPase) of erythrocyte-ghost membranes from patients with Duchenne muscular dystrophy (DMD) and carriers of DMD were compared with activities...
Foschi, M, Chari, S, Dunn, M J, Sorokin, A
Endothelin-1 (ET-1) induces cell proliferation and differentiation through multiple G-protein-linked signaling systems, including p21ras activation. Whereas p21ras activation and desensitization by...
The similarity of the two high-molecular-weight polypeptides of erythrocyte spectrin.
Dunn, M J, Kemp, R B, Maddy, A H
1. The two major polypeptides (P1 and P2) of erythrocyte-membrane spectrin were isolated by preparative polyacrylamide-gel electrophoresis. 2. The two polypeptides were shown to possess similar amino...
Induction of prostaglandin endoperoxide synthase 2 by mitogen-activated protein kinase cascades.
McGinty, A, Foschi, M, Chang, Y W, Han, J, Dunn, M J, Sorokin, A
Prostaglandin endoperoxide synthase (PGHS) catalyses the rate-limiting step in the formation of prostaglandin and thromboxane eicosanoids from arachidonic acid released by phospholipase A(2). Two...
Genomics, proteomics and bioinformatics of human heart failure
DOS REMEDIOS, C.G., LIEW, C.C., ALLEN, P.D., WINSLOW, R.L., VAN EYK, J.E., DUNN, M.J.
Unraveling the molecular complexities of human heart failure, particularly end-stage failure, can be achieved by combining multiple investigative approaches. There are several parts to the problem....
The newly isolated peptide, endothelin-1 (ET-1), is a potent pressor agent that reduces GFR and the glomerular ultrafiltration coefficient. Recent evidence demonstrates that ET-1 mobilizes...
Simonson, M S, Wann, S, Mené, P, Dubyak, G R, Kester, M, Nakazato, Y, ...
A recently described peptide hormone, endothelin, is a potent vasoconstrictor, but it is unclear whether endothelin has other biological actions. These experiments extend the range of biological...
The nucleotide sequence of a glutamine tRNA from rat liver.
Chan, J C, Yang, J A, Dunn, M J, Agris, P F, Wong, T W
A glutamate tRNA from rat liver was purified. By means of post-labeling techniques, its nucleotide sequence was shown to be: pU-C-C-C-A-C-A-U-m1G-G-U-C-psi-A-G-C-...
The nucleotide sequence of a glutamate tRNA from rat liver.
Chan, J C, Yang, J A, Dunn, M J, Agris, P F, Wong, T W
A glutamate tRNA from rat liver was purified. By means of post-labeling techniques, its nucleotide sequence was shown to be: pU-C-C-C-A-C-A-U-m1G-G-U-C-psi-A-G-C-...
Renal prostaglandin synthesis in the spontaneously hypertensive rat.
The precise role of the kidney in spontaneous experimental hypertension is unknown. We have analyzed the rates of renal prostaglandin synthesis by utilizing a spontaneously hypertensive rat model....
In vivo effect of indomethacin to potentiate the renal medullary cyclic AMP response to vasopressin.
Lum, G M, Aisenbrey, G A, Dunn, M J, Berl, T, Schrier, R W, McDonald, K M
In a previous study we demonstrated that indomethacin potentiated the hydro-osmotic action of vasopressin in vivo. It was hypothesized that this action of indomethacin was due to its ability to...
Monoclonal antibodies detect a spectrin-like protein in normal and dystrophic human skeletal muscle.
Appleyard, S T, Dunn, M J, Dubowitz, V, Scott, M L, Pittman, S J, Shotton, D M
Spectrin is the major protein of the erythrocyte membrane skeleton, which is bound to the cytoplasmic surface of the membrane's lipid bilayer and is responsible for cell shape and membrane...
Arginine vasopressin (AVP) and angiotensin II (ANG II) reduce the glomerular filtration rate and ultrafiltration coefficient. Vasodilatory prostaglandins (PG) antagonize these effects. AVP and ANG II...
Lianos, E A, Andres, G A, Dunn, M J
Glomerular arachidonate cyclooxygenation by isolated rat glomeruli was assessed in vitro in antiglomerular basement membrane (anti-GBM) antibody-induced glomerulonephritis by radioimmunoassay for...
Prostaglandin synthesis in isolated rat kidney glomeruli.
Hassid, A, Konieczkowski, M, Dunn, M J
Isolated rat kidney glomeruli converted octatritiated arachidonic acid to several prostaglandins whose production was inhibited by meclofenamate. These were, in order of decreasing abundance,...
Glomerular arachidonate lipoxygenation in rat nephrotoxic serum nephritis.
Lianos, E A, Rahman, M A, Dunn, M J
Arachidonate lipoxygenation to monohydroxylated eicosatetraenoic acids (HETE) was studied in rat nephrotoxic serum nephritis (NSN). A single infusion of nephrotoxic serum enhanced conversion of...
Increased leukotriene B4 synthesis in immune injured rat glomeruli.
Rahman, M A, Nakazawa, M, Emancipator, S N, Dunn, M J
We examined glomerular synthesis of the 5-lipoxygenase metabolite, LTB4, in normal and immune-injured rat glomeruli. Glomeruli isolated from normal rats and from rats with nephrotoxic serum nephritis...
Activation of extracellular signal-regulated kinase in proliferative glomerulonephritis in rats.
Bokemeyer, D, Guglielmi, K E, McGinty, A, Sorokin, A, Lianos, E A, Dunn, M J
Multiple extracellular mitogens are involved in the pathogenesis of proliferative forms of glomerulonephritis (GN). In vitro studies demonstrate the pivotal role of extracellular signal-regulated...
Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells.
Wang, Y, Simonson, M S, Pouysségur, J, Dunn, M J
Mitogen-activated protein (MAP) kinases are regarded as switch kinases in the phosphorylation cascade initiated by various agonists. We have investigated whether endothelins (ET), which are...
Thomas, C P, Dunn, M J, Mattera, R
The human leukaemic cell line K562 is a pluripotent stem cell with the potential to mature along a megakaryocytic or erythroid line. In these cells, thrombin and U46619 (9,11-dideoxy-9 alpha, 11...
Dunn, M J, Burghes, A H, Dubowitz, V
The Ca2+-stimulated Mg2-dependent ATPase activities (Ca2+-ATPase) of erythrocyte-ghost membranes from patients with Duchenne muscular dystrophy (DMD) and carriers of DMD were compared with activities...
Foschi, M, Chari, S, Dunn, M J, Sorokin, A
Endothelin-1 (ET-1) induces cell proliferation and differentiation through multiple G-protein-linked signaling systems, including p21ras activation. Whereas p21ras activation and desensitization by...
The similarity of the two high-molecular-weight polypeptides of erythrocyte spectrin.
Dunn, M J, Kemp, R B, Maddy, A H
1. The two major polypeptides (P1 and P2) of erythrocyte-membrane spectrin were isolated by preparative polyacrylamide-gel electrophoresis. 2. The two polypeptides were shown to possess similar amino...
Induction of prostaglandin endoperoxide synthase 2 by mitogen-activated protein kinase cascades.
McGinty, A, Foschi, M, Chang, Y W, Han, J, Dunn, M J, Sorokin, A
Prostaglandin endoperoxide synthase (PGHS) catalyses the rate-limiting step in the formation of prostaglandin and thromboxane eicosanoids from arachidonic acid released by phospholipase A(2). Two...
Penguin-mounted cameras glimpse underwater group behaviour.
Takahashi, A, Sato, K, Naito, Y, Dunn, M J, Trathan, P N, Croxall, J P
Marine birds and mammals spend most of their lives in the open ocean far from human observation, which makes obtaining information about their foraging behaviour difficult. Here, we show, by use of a...
Zhang, H., Morgan-Capner, P., Latif, N., Pandolfino, Y. A., Fan, W., Dunn, M. J., ...
Coxsackievirus B3 (CVB3) is the enterovirus most frequently involved in human myocarditis or dilated cardiomyopathy. Attenuated variants were derived from a cardiovirulent CVB3 reactivated from a...
Derry, C J, Dunn, M J, Rees, A J, Pusey, C D
The autoantigen in Goodpasture's syndrome is known to be contained within the non-collagenous (NC1) domain of type IV collagen. We have examined the specificity of autoantibodies to glomerular...