Scientific Commons: M. J. Field

Cyclosporin exerts a direct fibrogenic effect on human tubulointerstitial cells: Roles of insulin-like growth factor I, transofrming frowth factor B1, and platelet-derived growth factor1 (1999)

Johnson, D. W., Saunders, H. J., Johnson, F. J., Huq, S. O., Field, M. J., Pollock, C. A.

Fibrongenic effects of cyclosporin A on the tubulointerstitium: Role of cytokines and growth factors (1999)

Johnson, D. W., Saunders, H. J., Johnson, F. J., Huq, S. O., Field, M. J., Pollock, C. A.

Study of fresh microencapsulated islets with polylysine-alginate in xenografts (1992)

Field, M.J., Barneo, L., Chen, D.

Evidence for an involvement of the brain cholecystokinin B receptor in anxiety.

Singh, L, Lewis, A S, Field, M J, Hughes, J, Woodruff, G N

The effect of neuropeptide cholecystokinin (CCK) receptor agonists and antagonists was examined in the rat elevated X-maze model of anxiety. The selective CCK-B receptor antagonists CI-988 (PD...

Differential acute effects of aldosterone, dexamethasone, and hyperkalemia on distal tubular potassium secretion in the rat kidney.

Field, M J, Stanton, B A, Giebisch, G H

To determine the specific effects on renal potassium transport of acute elevations in plasma aldosterone, dexamethasone, and potassium concentrations, we studied adrenalectomized rats prepared such...

Proximal tubular cell electrolytes during volume expansion in the rat.

Reddy, S, Györy, A Z, Boström, T, Dyne, M, Salipan-Moore, N, Field, M J, ...

1. Proximal tubular intracellular elements were measured by electron microprobe X-ray analysis (a) in rats volume-expanded with albumin-saline in which peritubular oncotic pressure remained normal...

Transferable circulating factors and epithelial sodium transport after unilateral nephrectomy in the rat.

Pollock, C A, Nobes, M S, Gyory, A Z, Heng, P T, Field, M J

1. In order to investigate the role of circulating serum factors in the altered renal haemodynamics and enhanced renal tubular transport observed in renal growth, micropuncture experiments were...

Carotinaemia in the Tropics

Field, M. J.

Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents

Field, M J, Oles, R J, Lewis, A S, McCleary, S, Hughes, J, Singh, L

Gabapentin (neurontin) is a novel antiepileptic agent that binds to the α2δ subunit of voltage-dependent calcium channels. The only other compound known to possess affinity for this recognition...

Effect of chronic ethanol treatment in vivo on excitability in mouse cortical neurones in vitro

Ibbotson, T, Field, M J, Boden, P R

The effects of cessation of chronic ethanol ingestion on seizure activity in vivo and on the characteristics of the evoked synaptic potentials in cortical neurones in vitro have been investigated in...

The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist.

Singh, L., Field, M. J., Hughes, J., Menzies, R., Oles, R. J., Vass, C. A., ...

1. The behavioural effects of a selective cholecystokininB (CCKB) receptor antagonist CI-988 were investigated in rodents. 2. In three rodent tests of anxiety (rat elevated X-maze, rat social...

The antagonism of benzodiazepine withdrawal effects by the selective cholecystokininB receptor antagonist CI-988.

Singh, L., Field, M. J., Vass, C. A., Hughes, J., Woodruff, G. N.

The ability of a selective cholecystokininB (CCKB) receptor antagonist, CI-988, to block benzodiazepine withdrawal effects was examined in mice. The discontinuation of twice daily administration of...

Effect of CCK receptor antagonists on the antinociceptive, reinforcing and gut motility properties of morphine.

Singh, L., Oles, R. J., Field, M. J., Atwal, P., Woodruff, G. N., Hunter, J. C.

1. The ability of a selective CCKA receptor antagonist PD 140548 and a selective CCKB receptor antagonist CI-988 (formerly PD 134308) to modulate the various in vivo properties of morphine was...

M. J. Field

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