"Buzz-saw" noise: a comparison of modal measurements with an improved prediction method (2007)
McAlpine, A., Fisher, M.J., Tester, B.J.
“Buzz-saw” noise is radiated from a turbofan inlet duct when the fan tip speed is supersonic. In a recent article the effect of an acoustic liner on buzz-saw noise has been examined. Spectral...
"Buzz-saw" noise: a comparison of measurement with prediction (2006)
McAlpine, A., Fisher, M.J., Tester, B.J.
Accurate prediction of “buzz-saw” noise in a turbofan inlet duct necessitates consideration of nonlinear acoustics, modelling a complete fan blade set, modelling an acoustic liner, and...
IHAS-4 Softwave Report. (2005)
Fisher,M. J., Galanti,C., Haddon,D.
A brief description is given of a complementary software package developed for in-house use of the IHAS-4 computer. The package consists of a basic two-pass assembler and a simulator that simulates...
On the prediction of "buzz-saw" noise in acoustically lined aero-engine inlet ducts (2003)
Aero-engines operating with supersonic fan tip speeds generate an acoustic signature containing energy spread over a range of harmonics of the engine shaft rotation frequency. These harmonics are...
A CFD Coupled Acoustics Approach for the Prediction of Coaxial Jet Noise (2003)
Page, G. J., McGuirk, J. J., Behrouzi, P., Hossain, M., Fisher, M. J.
Prediction of jet noise is important for civil aircraft. Some CAA methodologies predict the full unsteady flow field of a jet in order to ascertain the far-field noise. The approach adopted here is...
Aeroacoustics research in Europe: The CEAS-ASC report on 2001 highlights (2002)
This paper summarizes some highlights of aeroacoustics research in Europe in 2001, compiled from information provided to the Confederation of European Aerospace Societies (CEAS) Aeroacoustics...
Research in aero-acoustics at the ISVR (2002)
Astley, R.J., Fisher, M.J., Holland, K.R., Joseph, P.F., McAlpine, A., Self, R.H., ...
Aeroacoustics research in Europe: The CEAS-ASC report on 2001 highlights (2002)
This paper summarizes some highlights of aeroacoustics research in Europe in 2001, compiled from information provided to the Confederation of European Aerospace Societies (CEAS) Aeroacoustics...
Foundations of Knowledge for Distributed Systems. (2002)
Halpern and Moses present an interesting discussion of knowledge and common knowledge and common knowledge for distributed systems. They argue that while common knowledge is desirable, it is...
On the prediction of "buzz-saw" noise in aero-engine inlet ducts (2001)
"Buzz-saw" noise radiated from an aero-engine inlet duct occurs when the relative speed of the inlet flow impinging on the fan blades is supersonic. The pressure field attached to a supersonic ducted...
The noise sources in a jet can be related to the turbulent velocity fluctuations in the mixing region. The structure and characteristics of the turbulence have been studied experimentally and the...
Design of a Kalman Derived, Fixed Gain, Hybrid Navigation System. (1998)
Clark, R. F., Elliott, C. T., Fisher, M. J., Galanti, C. J.
(*NAVIGATION, ARMY AIRCRAFT), LORAN, INERTIAL NAVIGATION, DESIGN, GAIN, COMPUTER PROGRAMMING, MATHEMATICAL MODELS, SIMULATIONKALMAN FILTERS, COMPUTERIZED SIMULATIONAt present, there exists a major...
The role of nickel in the cyanidation and recovery of gold (1998)
Thesis submitted to the Division of Science. Bibliography: leaves 210-224.
The effect of streptozotocin-induced diabetes on phenylalanine hydroxylase expression in rat liver.
Taylor, D S, Dahl, H H, Mercer, J F, Green, A K, Fisher, M J
The impact of experimentally induced diabetes on the expression of rat liver phenylalanine hydroxylase has been investigated. A significant elevation in maximal enzymic activity was observed in...
Richardson, S C, Aspbury, R A, Fisher, M J
Reversible phosphorylation is the major mechanism underlying the short-term hormonal control of phenylalanine hydroxylase activity in the liver. We report here, for the first time, the impact of a...
Shergill, J K, Cammack, R, Chen, J H, Fisher, M J, Madden, S, Rees, H H
EPR spectroscopy was used to investigate the cytochrome P-450-dependent steroid hydroxylase ecdysone 20-mono-oxygenase of the cotton leafworm (Spodoptera littoralis) and the redox centres associated...
Experimental determination of the phosphorylation state of phenylalanine hydroxylase.
Green, A K, Cotton, R G, Jennings, I, Fisher, M J
A monoclonal antibody (PH 7), which recognizes the phosphorylated form of phenylalanine hydroxylase from human liver, has been used for the analysis of the enzyme in crude cell extracts from rat. In...
Chen, J H, Kabbouh, M, Fisher, M J, Rees, H H
Treatment of the last-instar larvae of the cotton leafworm (Spodoptera littoralis) with ecdysteroids (moulting hormones) results in the induction of an ecdysteroid-inactivation pathway....
Chen, J H, Hara, T, Fisher, M J, Rees, H H
The developmental changes in ecdysone 20-mono-oxygenase during the sixth larval instar of the cotton leafworm, Spodoptera littoralis, were investigated. The specific activity of mitochondrial...
Salter, M, Stanley, J C, Fisher, M J, Pogson, C I
Liver cells from fed Sprague-Dawley rats metabolized phenylalanine, tyrosine and tryptophan at rates consistent with the known kinetic properties of the first enzymes of each pathway. Starvation of...
The effect of experimental diabetes on phenylalanine metabolism in isolated liver cells.
Santana, M A, Fisher, M J, Bate, A J, Pogson, C I
Chronic (10-day) diabetes was associated with increased metabolic flux through phenylalanine hydroxylase in isolated liver cells. This flux was stimulated by 0.1 microM-glucagon, but not by 10...
Stanley, J C, Fisher, M J, Pogson, C I
Flux through, and maximal activities of, key enzymes of phenylalanine and tyrosine degradation were measured in liver cells prepared from adrenalectomized rats and from streptozotocin-diabetic rats....
Fisher, M J, Dickson, A J, Pogson, C I
The role of polyamines in the control of phenylalanine hydroxylase phosphorylation state and enzymic activity was investigated. Pre-treatment of liver cells with spermine (1 mM) abolishes the...
Fisher, M J, Dickson, A J, Pogson, C I
The stimulation of phenylalanine hydroxylation in isolated liver cells by sub-maximally effective concentrations of glucagon (less than 0.1 microM) is antagonized by insulin (0.1 nM-0.1 microM). This...
Fisher, M J, Dickson, A J, Pogson, C I
Hormonal control of the phosphorylation of phenylalanine hydroxylase was studied by using rat liver cells incubated with [32P]Pi. After immunoprecipitation from cell extracts, the hydroxylase was...
Phenylalanine is transported rapidly into, but is not concentrated by, liver cells. Glucagon increased flux through phenylalanine hydroxylase; a half-maximal response was obtained at 0.7 nM. Under...
Fisher, M J, Santana, M A, Pogson, C I
The adrenergic amines noradrenaline and adrenaline increased flux through phenylalanine hydroxylase by approx. 50%. This effect, which appears to be mediated by an alpha-adrenergic mechanism, was...
Edgecombe, M, McLennan, A G, Fisher, M J
Diadenosine polyphosphates present in the extracellular environment can, through interaction with appropriate purinoceptors, influence a range of cellular activities. Here we have investigated the...
Diadenosine polyphosphate-stimulated gluconeogenesis in isolated rat proximal tubules.
Edgecombe, M, Craddock, H S, Smith, D C, McLennan, A G, Fisher, M J
Diadenosine polyphosphates released into the extracellular environment influence a variety of metabolic and other cellular activities in a wide range of target tissues. Here we have studied the...
Tabish, M, Clegg, R A, Rees, H H, Fisher, M J
The cAMP-dependent protein kinase (protein kinase A, PK-A) is multifunctional in nature, with key roles in the control of diverse aspects of eukaryotic cellular activity. In the case of the...
Hepatitis, cardiomyopathy and hemodynamics in furazolidone-induced round heart disease of turkeys.
Simpson, C F, Rollinghoff, W, Preisig, R, Fisher, M J
Twenty-five large broad-breasted white turkeys were fed a 22% protein diet supplemented with 500 ppm furazolidone from day 1 to 3.5 weeks of age and the same diet supplemented with 700 ppm...
The effect of streptozotocin-induced diabetes on phenylalanine hydroxylase expression in rat liver.
Taylor, D S, Dahl, H H, Mercer, J F, Green, A K, Fisher, M J
The impact of experimentally induced diabetes on the expression of rat liver phenylalanine hydroxylase has been investigated. A significant elevation in maximal enzymic activity was observed in...
Richardson, S C, Aspbury, R A, Fisher, M J
Reversible phosphorylation is the major mechanism underlying the short-term hormonal control of phenylalanine hydroxylase activity in the liver. We report here, for the first time, the impact of a...
Shergill, J K, Cammack, R, Chen, J H, Fisher, M J, Madden, S, Rees, H H
EPR spectroscopy was used to investigate the cytochrome P-450-dependent steroid hydroxylase ecdysone 20-mono-oxygenase of the cotton leafworm (Spodoptera littoralis) and the redox centres associated...
Experimental determination of the phosphorylation state of phenylalanine hydroxylase.
Green, A K, Cotton, R G, Jennings, I, Fisher, M J
A monoclonal antibody (PH 7), which recognizes the phosphorylated form of phenylalanine hydroxylase from human liver, has been used for the analysis of the enzyme in crude cell extracts from rat. In...
Chen, J H, Kabbouh, M, Fisher, M J, Rees, H H
Treatment of the last-instar larvae of the cotton leafworm (Spodoptera littoralis) with ecdysteroids (moulting hormones) results in the induction of an ecdysteroid-inactivation pathway....
Chen, J H, Hara, T, Fisher, M J, Rees, H H
The developmental changes in ecdysone 20-mono-oxygenase during the sixth larval instar of the cotton leafworm, Spodoptera littoralis, were investigated. The specific activity of mitochondrial...
Salter, M, Stanley, J C, Fisher, M J, Pogson, C I
Liver cells from fed Sprague-Dawley rats metabolized phenylalanine, tyrosine and tryptophan at rates consistent with the known kinetic properties of the first enzymes of each pathway. Starvation of...
The effect of experimental diabetes on phenylalanine metabolism in isolated liver cells.
Santana, M A, Fisher, M J, Bate, A J, Pogson, C I
Chronic (10-day) diabetes was associated with increased metabolic flux through phenylalanine hydroxylase in isolated liver cells. This flux was stimulated by 0.1 microM-glucagon, but not by 10...
Stanley, J C, Fisher, M J, Pogson, C I
Flux through, and maximal activities of, key enzymes of phenylalanine and tyrosine degradation were measured in liver cells prepared from adrenalectomized rats and from streptozotocin-diabetic rats....
Fisher, M J, Dickson, A J, Pogson, C I
The role of polyamines in the control of phenylalanine hydroxylase phosphorylation state and enzymic activity was investigated. Pre-treatment of liver cells with spermine (1 mM) abolishes the...
Fisher, M J, Dickson, A J, Pogson, C I
The stimulation of phenylalanine hydroxylation in isolated liver cells by sub-maximally effective concentrations of glucagon (less than 0.1 microM) is antagonized by insulin (0.1 nM-0.1 microM). This...
Fisher, M J, Dickson, A J, Pogson, C I
Hormonal control of the phosphorylation of phenylalanine hydroxylase was studied by using rat liver cells incubated with [32P]Pi. After immunoprecipitation from cell extracts, the hydroxylase was...
Phenylalanine is transported rapidly into, but is not concentrated by, liver cells. Glucagon increased flux through phenylalanine hydroxylase; a half-maximal response was obtained at 0.7 nM. Under...
Fisher, M J, Santana, M A, Pogson, C I
The adrenergic amines noradrenaline and adrenaline increased flux through phenylalanine hydroxylase by approx. 50%. This effect, which appears to be mediated by an alpha-adrenergic mechanism, was...
Edgecombe, M, McLennan, A G, Fisher, M J
Diadenosine polyphosphates present in the extracellular environment can, through interaction with appropriate purinoceptors, influence a range of cellular activities. Here we have investigated the...
Diadenosine polyphosphate-stimulated gluconeogenesis in isolated rat proximal tubules.
Edgecombe, M, Craddock, H S, Smith, D C, McLennan, A G, Fisher, M J
Diadenosine polyphosphates released into the extracellular environment influence a variety of metabolic and other cellular activities in a wide range of target tissues. Here we have studied the...
Tabish, M, Clegg, R A, Rees, H H, Fisher, M J
The cAMP-dependent protein kinase (protein kinase A, PK-A) is multifunctional in nature, with key roles in the control of diverse aspects of eukaryotic cellular activity. In the case of the...
Hepatitis, cardiomyopathy and hemodynamics in furazolidone-induced round heart disease of turkeys.
Simpson, C F, Rollinghoff, W, Preisig, R, Fisher, M J
Twenty-five large broad-breasted white turkeys were fed a 22% protein diet supplemented with 500 ppm furazolidone from day 1 to 3.5 weeks of age and the same diet supplemented with 700 ppm...
Sleep and nocturnal acid reflux in normal subjects and patients with reflux oesophagitis.
Freidin, N, Fisher, M J, Taylor, W, Boyd, D, Surratt, P, McCallum, R W, ...
Nocturnal gastro-oesophageal reflux may be important in the pathogenesis of reflux oesophagitis. This study aimed to determine whether: (1) gastro-oesophageal reflux occurs during sleep in patients...