Ledergerber, B., Phillips, A., Lundgren, J., Walker, A.S., Sabin, C., Justice, A., ...
Summary: Background: Treatment strategies for patients in whom HIV replication is not suppressed after exposure to several drug classes remain unclear. We aimed to assess the inter-relations between...
Gill, M. J., Simjee, S., Al-Hattawi, K., Robertson, B. D., Easmon, C. S. F., Ison, C. A.
penB is a chromosomal mutation that confers resistance to β-lactams and tetracyclines and reduced susceptibility to quinolones in Neisseria gonorrhoeae. It is linked to the porin gene (por) and...
Morita, M, Suzuki, T, Nakajima, K, Shiozawa, C, Gill, M J, Hoshino, H
Antibodies against reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) have been detected in seropositive subjects by immunoprecipitation, Western immunoblotting, and...
Functional characterization of a sialyltransferase-deficient mutant of Neisseria gonorrhoeae.
Gill, M J, McQuillen, D P, Van Putten, J P, Wetzler, L M, Bramley, J, Crooke, H, ...
Previous studies indicate that sialylation of lipopolysaccharide (LPS) by host CMP-N-acetylneuraminic acid (CMP-NANA) catalyzed by bacterial sialyltransferase rendered gonococci resistant to killing...
Pharmacokinetics and metabolism of E-5-(2-[131I]iodovinyl)-2'-deoxyuridine in dogs.
Samuel, J, Gill, M J, Iwashina, T, Tovell, D R, Tyrrell, D L, Knaus, E E, ...
E-5-(2-Iodovinyl)-2'-deoxyuridine (IVdU) is a potent inhibitor of herpes simplex virus type 1 replication in vitro. The selective antiviral activity of IVdU is due to preferential phosphorylation by...
Gill, M J, Samuel, J, Wiebe, L I, Knaus, E E, Tyrrell, D L
We have synthesized a 131I-radiolabeled antiviral compound (E)-5-(2-iodovinyl)-2'-deoxyuridine (IVdU) and shown that this agent was selectively trapped within rabbit kidney cells, infected in vitro...
Cassol, S, Gill, M J, Pilon, R, Cormier, M, Voigt, R F, Willoughby, B, ...
To assess dried plasma spots (DPSs) as a source of material for virus quantification, human immunodeficiency virus type 1 (HIV-1) RNA levels were quantified in matched DPS and liquid plasma samples...
Oral acyclovir therapy of recurrent herpes simplex virus type 2 infection of the hand.
Acyclovir was evaluated as treatment of recurrent herpes simplex virus type 2 infection of the hand in a double-blind, placebo-controlled crossover study. In nine fully evaluable patients, oral...
"Campylobacter cinaedi" bacteremia: case report and laboratory findings.
Cimolai, N, Gill, M J, Jones, A, Flores, B, Stamm, W E, Laurie, W, ...
"Campylobacter cinaedi" was isolated from the blood of a 29-year-old homosexual man with previously diagnosed acquired immune deficiency syndrome. Subculturing of the organism was achieved with the...
Cassol, S, Salas, T, Gill, M J, Montpetit, M, Rudnik, J, Sy, C T, ...
Blood sampling on filter paper has many advantages for the detection of perinatal human immunodeficiency virus (HIV) infection by the polymerase chain reaction (PCR). However, if the method is to be...
Agar dilution breakpoint susceptibility testing using GC, DST, and proteose agars, was performed on consecutive clinical isolates of non-penicillinase producing Neisseria gonorrhoeae to examine the...
Use of blood donation history of people with HIV infection to identify recipients at risk.
Gill, M J, Meyers, G, Rajwani, A
OBJECTIVE: To determine whether previous blood donations from HIV-positive patients posed a threat to recipients. DESIGN: Interviewer-administered questionnaire survey. SETTING: Regional HIV...
Gastrointestinal function and structure in HIV-positive patients.
Sutherland, L R, Church, D L, Gill, M J, Kelly, J K, Hwang, W S, Bryant, H E
We examined 19 patients (17 men) with human immunodeficiency virus (HIV) infection and gastrointestinal symptoms to determine whether those symptoms were due to either a gastrointestinal tract...
Gill, M. J., Simjee, S., Al-Hattawi, K., Robertson, B. D., Easmon, C. S. F., Ison, C. A.
penB is a chromosomal mutation that confers resistance to β-lactams and tetracyclines and reduced susceptibility to quinolones in Neisseria gonorrhoeae. It is linked to the porin gene (por) and...
Morita, M, Suzuki, T, Nakajima, K, Shiozawa, C, Gill, M J, Hoshino, H
Antibodies against reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) have been detected in seropositive subjects by immunoprecipitation, Western immunoblotting, and...
Functional characterization of a sialyltransferase-deficient mutant of Neisseria gonorrhoeae.
Gill, M J, McQuillen, D P, Van Putten, J P, Wetzler, L M, Bramley, J, Crooke, H, ...
Previous studies indicate that sialylation of lipopolysaccharide (LPS) by host CMP-N-acetylneuraminic acid (CMP-NANA) catalyzed by bacterial sialyltransferase rendered gonococci resistant to killing...
Pharmacokinetics and metabolism of E-5-(2-[131I]iodovinyl)-2'-deoxyuridine in dogs.
Samuel, J, Gill, M J, Iwashina, T, Tovell, D R, Tyrrell, D L, Knaus, E E, ...
E-5-(2-Iodovinyl)-2'-deoxyuridine (IVdU) is a potent inhibitor of herpes simplex virus type 1 replication in vitro. The selective antiviral activity of IVdU is due to preferential phosphorylation by...
Gill, M J, Samuel, J, Wiebe, L I, Knaus, E E, Tyrrell, D L
We have synthesized a 131I-radiolabeled antiviral compound (E)-5-(2-iodovinyl)-2'-deoxyuridine (IVdU) and shown that this agent was selectively trapped within rabbit kidney cells, infected in vitro...
Cassol, S, Gill, M J, Pilon, R, Cormier, M, Voigt, R F, Willoughby, B, ...
To assess dried plasma spots (DPSs) as a source of material for virus quantification, human immunodeficiency virus type 1 (HIV-1) RNA levels were quantified in matched DPS and liquid plasma samples...
Oral acyclovir therapy of recurrent herpes simplex virus type 2 infection of the hand.
Acyclovir was evaluated as treatment of recurrent herpes simplex virus type 2 infection of the hand in a double-blind, placebo-controlled crossover study. In nine fully evaluable patients, oral...
"Campylobacter cinaedi" bacteremia: case report and laboratory findings.
Cimolai, N, Gill, M J, Jones, A, Flores, B, Stamm, W E, Laurie, W, ...
"Campylobacter cinaedi" was isolated from the blood of a 29-year-old homosexual man with previously diagnosed acquired immune deficiency syndrome. Subculturing of the organism was achieved with the...
Cassol, S, Salas, T, Gill, M J, Montpetit, M, Rudnik, J, Sy, C T, ...
Blood sampling on filter paper has many advantages for the detection of perinatal human immunodeficiency virus (HIV) infection by the polymerase chain reaction (PCR). However, if the method is to be...
Agar dilution breakpoint susceptibility testing using GC, DST, and proteose agars, was performed on consecutive clinical isolates of non-penicillinase producing Neisseria gonorrhoeae to examine the...
Use of blood donation history of people with HIV infection to identify recipients at risk.
Gill, M J, Meyers, G, Rajwani, A
OBJECTIVE: To determine whether previous blood donations from HIV-positive patients posed a threat to recipients. DESIGN: Interviewer-administered questionnaire survey. SETTING: Regional HIV...
Gastrointestinal function and structure in HIV-positive patients.
Sutherland, L R, Church, D L, Gill, M J, Kelly, J K, Hwang, W S, Bryant, H E
We examined 19 patients (17 men) with human immunodeficiency virus (HIV) infection and gastrointestinal symptoms to determine whether those symptoms were due to either a gastrointestinal tract...
Transfer of beta-lactamase plasmids by conjugation in Neisseria gonorrhoeae.
Ison, C A, Gill, M J, Woodford, N
Conjugation experiments in vitro have been used in an attempt to explain certain epidemiological phenomena seen amongst penicillinase producing Neisseria gonorrhoeae (PPNG) isolated at St Mary's...
Penicillin and cephalosporin resistance in gonococci.
Ison, C A, Bindayna, K M, Woodford, N, Gill, M J, Easmon, C S
Non-penicillinase producing Neisseria gonorrhoeae isolated at St Mary's Hospital, London were examined for the prevalence of resistance to penicillin and for decreased susceptibility to cefuroxime....