Harrington, D.J., Soper, R., Edwards, C., Savidge, G.F., Hodges, S.J., Shearer, M.J.
We describe a method for the determination of the two major urinary metabolites of vitamin K as the methyl esters of their agyclone structures, 2-methyl-3-(3-3-carboxymethylpropyl)-1,4-naphthoquinone...
Pereira, S.P., Rowbotham, D., Fitt, S., Shearer, M.J., Wendon, J., Williams, R.
Background/Aims: in patients with severe acute liver dysfunction, i.v. phylloquinone (vitamin K1) may be given to exclude vitamin K deficiency, rather than impaired hepatic synthesis of coagulation...
O'Brien, D P, Shearer, M J, Waldron, R P, Horgan, P G, Given, H F
Eleven patients with cholestatic jaundice had measurements of plasma vitamin K1 performed. Seven of these 11 (64%) had subnormal levels. The prothrombin time (PT) was prolonged in three of 15...
O'Brien, D P, Shearer, M J, Waldron, R P, Horgan, P G, Given, H F
Eleven patients with cholestatic jaundice had measurements of plasma vitamin K1 performed. Seven of these 11 (64%) had subnormal levels. The prothrombin time (PT) was prolonged in three of 15...
Plasma concentrations after oral or intramuscular vitamin K1 in neonates.
McNinch, A W, Upton, C, Samuels, M, Shearer, M J, McCarthy, P, Tripp, J H, ...
One hundred and seven healthy, breast fed infants received 1 mg vitamin K1 either at birth (orally or intramuscularly) or with the first feed (orally). Venous blood samples collected in the next 24...