Victora, Cesar G., Huttly, Sharon R.A., Fuchs, S.C., Barros, F.C., Garenne, M., Leroy, O., ...
Population-based data on deaths due to diarrhoea among children less than 5 years of age were obtained from areas of Brazil (227 deaths), Senegal (531), Bangladesh (236) and India (146). Fatal...
Effect of zinc supplementation on clinical course of acute diaffhoea (2001)
Bahl, R., Baqui, A., Bhan, M.K., Bhatnagar, S., Black, R.E., Brooks, A., ...
Evaluation of an algorithm for the treatment of persistent diarrhoea: a multicentre study (1996)
Ashraf, H., Bhan, M.K., Bhatnagar, S., Bhutta, Z., Brown, K.H., Dung, P.T., ...
Clinical trials of improved oral rehydration salt formulations: a review (1994)
Bhan, M.K., Mahalanabis, D., Fontaine, O., Pierce, N.F.
(ORS), L-alanine-based ORS, L-glutamine-based ORS, maltodextrin-based ORS, and rice-based ORS, as well as the results of several recently completed, but unpublished, studies of these formulations...
Coulson, Barbara S., Gentsch, Jon R., Das, Bimal K., Bhan, M. K., Glass, Roger I.
While only four globally important rotavirus G serotypes (1 to 4) have been documented, many studies suggest that serotype G9 viruses may be widely distributed and more important than previously...
Ramachandran, Madhumati, Vij, Aarti, Kumar, Ramesh, Das, Bimal K., Gentsch, Jon R., Bhan, M. K., ...
Rotavirus (RV) strains infecting newborns often have unique neutralization antigens (P serotypes) on their outer capsids that are distinct from those found on RV strains that cause diarrhea in older...
Debroy, C, Yealy, J, Wilson, R A, Bhan, M K, Kumar, R
Enteroaggregative Escherichia coli (EAggEC) is a distinct category of diarrheal pathogen implicated as the cause of persistent diarrhea. The pathogen exhibits a characteristic "stacked-brick" pattern...
Valvatne, H, Sommerfelt, H, Gaastra, W, Bhan, M K, Grewal, H M
An enterotoxigenic Escherichia coli (ETEC) strain producing a previously undescribed putative colonization factor was isolated from a child with diarrhea in India. Sodium dodecyl...
A new putative fimbrial colonization factor, CS19, of human enterotoxigenic Escherichia coli.
Grewal, H M, Valvatne, H, Bhan, M K, Van Dijk, L, Gaastra, W, Sommerfelt, H
A gene probe derived from the colonization factor antigen I (CFA/I) operon cross-hybridized at very low stringency to plasmid DNA from coli surface antigen 17 (CS17)-producing enterotoxigenic...
Unusual diversity of human rotavirus G and P genotypes in India.
Ramachandran, M, Das, B K, Vij, A, Kumar, R, Bhambal, S S, Kesari, N, ...
Between April and December 1993, we determined P and G genotypes of group A rotavirus strains obtained from children admitted to diarrhea treatment centers in five Indian cities. From a total of 63...
Ability of enteroaggregative Escherichia coli strains to adhere in vitro to human intestinal mucosa.
Knutton, S, Shaw, R K, Bhan, M K, Smith, H R, McConnell, M M, Cheasty, T, ...
A collection of 44 enteroaggregative Escherichia coli (EAggEC) strains isolated from infants with diarrhea in India and the United Kingdom were examined for their ability to adhere in vitro to human...
Sommerfelt, H, Grewal, H M, Svennerholm, A M, Gaastra, W, Flood, P R, Viboud, G, ...
Plasmid DNA from two strains of enterotoxigenic Escherichia coli harboring genes encoding coli surface antigen 4 (CS4) and from seven Indian enterotoxigenic E. coli isolates cross-hybridized at low...
Shariff, M, Bhan, M K, Knutton, S, Das, B K, Saini, S, Kumar, R
Enteropathogenic Escherichia coli (EPEC) strains designated on the basis of their serotypes are epidemiologically associated with diarrhea. They adhere to the intestinal mucosa, producing the...
Grewal, H M, Helander, A, Svennerholm, A M, Bhan, M K, Gaastra, W, Sommerfelt, H
A polynucleotide probe comprising the gene encoding a major structural subunit protein of coli surface antigen 6 (CS6) of enterotoxigenic Escherichia coli (ETEC) was developed. Eighty-nine ETEC...
Characterization of rotavirus strains from newborns in New Delhi, India.
Das, B K, Gentsch, J R, Cicirello, H G, Woods, P A, Gupta, A, Ramachandran, M, ...
Between 1986 and 1993, 72% of rotavirus strains isolated from newborns at five hospitals in New Delhi, India, had long electropherotypes, subgroup II VP6 antigens, and G and P genotypes (G9P11)...
Identification of group A rotavirus gene 4 types by polymerase chain reaction.
Gentsch, J R, Glass, R I, Woods, P, Gouvea, V, Gorziglia, M, Flores, J, ...
Five genetically distinct human rotavirus (HRV) gene 4 groups have been described on the basis of comparative nucleotide sequencing and the predicted amino acid sequences, and at least four of them...
Sommerfelt, H, Grewal, H M, Gaastra, W, Svennerholm, A M, Bhan, M K
We developed an accurate nonradioactive colony hybridization assay (NCHA) using a digoxigenin-labeled polynucleotide probe and an antidigoxigenin alkaline phosphatase conjugate for the identification...
Sommerfelt, H, Kalland, K H, Raj, P, Moseley, S L, Bhan, M K, Bjorvatn, B
Restriction endonuclease-generated polynucleotide and synthetically produced oligonucleotide gene probes used in colony hybridization assays proved to be efficient for the detection and...
Grewal, H M, Sommerfelt, H, Gaastra, W, Svennerholm, A M, Bhan, M K, Hamers, A M, ...
We compared a new colony hybridization assay with an established enzyme-linked immunosorbent assay for detection of enterotoxigenic Escherichia coli (ETEC) expressing colonization factor antigen I...
Sommerfelt, H, Grewal, H M, Bhan, M K
The present study describes a colony hybridization setup for identification of enterotoxigenic Escherichia coli obviating the need for advanced equipment and radioactive isotopes. With a modest...
Coulson, Barbara S., Gentsch, Jon R., Das, Bimal K., Bhan, M. K., Glass, Roger I.
While only four globally important rotavirus G serotypes (1 to 4) have been documented, many studies suggest that serotype G9 viruses may be widely distributed and more important than previously...
Ramachandran, Madhumati, Vij, Aarti, Kumar, Ramesh, Das, Bimal K., Gentsch, Jon R., Bhan, M. K., ...
Rotavirus (RV) strains infecting newborns often have unique neutralization antigens (P serotypes) on their outer capsids that are distinct from those found on RV strains that cause diarrhea in older...
Debroy, C, Yealy, J, Wilson, R A, Bhan, M K, Kumar, R
Enteroaggregative Escherichia coli (EAggEC) is a distinct category of diarrheal pathogen implicated as the cause of persistent diarrhea. The pathogen exhibits a characteristic "stacked-brick" pattern...
Valvatne, H, Sommerfelt, H, Gaastra, W, Bhan, M K, Grewal, H M
An enterotoxigenic Escherichia coli (ETEC) strain producing a previously undescribed putative colonization factor was isolated from a child with diarrhea in India. Sodium dodecyl...
A new putative fimbrial colonization factor, CS19, of human enterotoxigenic Escherichia coli.
Grewal, H M, Valvatne, H, Bhan, M K, Van Dijk, L, Gaastra, W, Sommerfelt, H
A gene probe derived from the colonization factor antigen I (CFA/I) operon cross-hybridized at very low stringency to plasmid DNA from coli surface antigen 17 (CS17)-producing enterotoxigenic...
Unusual diversity of human rotavirus G and P genotypes in India.
Ramachandran, M, Das, B K, Vij, A, Kumar, R, Bhambal, S S, Kesari, N, ...
Between April and December 1993, we determined P and G genotypes of group A rotavirus strains obtained from children admitted to diarrhea treatment centers in five Indian cities. From a total of 63...
Ability of enteroaggregative Escherichia coli strains to adhere in vitro to human intestinal mucosa.
Knutton, S, Shaw, R K, Bhan, M K, Smith, H R, McConnell, M M, Cheasty, T, ...
A collection of 44 enteroaggregative Escherichia coli (EAggEC) strains isolated from infants with diarrhea in India and the United Kingdom were examined for their ability to adhere in vitro to human...
Sommerfelt, H, Grewal, H M, Svennerholm, A M, Gaastra, W, Flood, P R, Viboud, G, ...
Plasmid DNA from two strains of enterotoxigenic Escherichia coli harboring genes encoding coli surface antigen 4 (CS4) and from seven Indian enterotoxigenic E. coli isolates cross-hybridized at low...
Shariff, M, Bhan, M K, Knutton, S, Das, B K, Saini, S, Kumar, R
Enteropathogenic Escherichia coli (EPEC) strains designated on the basis of their serotypes are epidemiologically associated with diarrhea. They adhere to the intestinal mucosa, producing the...
Grewal, H M, Helander, A, Svennerholm, A M, Bhan, M K, Gaastra, W, Sommerfelt, H
A polynucleotide probe comprising the gene encoding a major structural subunit protein of coli surface antigen 6 (CS6) of enterotoxigenic Escherichia coli (ETEC) was developed. Eighty-nine ETEC...
Characterization of rotavirus strains from newborns in New Delhi, India.
Das, B K, Gentsch, J R, Cicirello, H G, Woods, P A, Gupta, A, Ramachandran, M, ...
Between 1986 and 1993, 72% of rotavirus strains isolated from newborns at five hospitals in New Delhi, India, had long electropherotypes, subgroup II VP6 antigens, and G and P genotypes (G9P11)...
Identification of group A rotavirus gene 4 types by polymerase chain reaction.
Gentsch, J R, Glass, R I, Woods, P, Gouvea, V, Gorziglia, M, Flores, J, ...
Five genetically distinct human rotavirus (HRV) gene 4 groups have been described on the basis of comparative nucleotide sequencing and the predicted amino acid sequences, and at least four of them...
Sommerfelt, H, Grewal, H M, Gaastra, W, Svennerholm, A M, Bhan, M K
We developed an accurate nonradioactive colony hybridization assay (NCHA) using a digoxigenin-labeled polynucleotide probe and an antidigoxigenin alkaline phosphatase conjugate for the identification...
Sommerfelt, H, Kalland, K H, Raj, P, Moseley, S L, Bhan, M K, Bjorvatn, B
Restriction endonuclease-generated polynucleotide and synthetically produced oligonucleotide gene probes used in colony hybridization assays proved to be efficient for the detection and...
Grewal, H M, Sommerfelt, H, Gaastra, W, Svennerholm, A M, Bhan, M K, Hamers, A M, ...
We compared a new colony hybridization assay with an established enzyme-linked immunosorbent assay for detection of enterotoxigenic Escherichia coli (ETEC) expressing colonization factor antigen I...
Sommerfelt, H, Grewal, H M, Bhan, M K
The present study describes a colony hybridization setup for identification of enterotoxigenic Escherichia coli obviating the need for advanced equipment and radioactive isotopes. With a modest...
Association of antecedent malnutrition with persistent diarrhoea: a case-control study.
Bhandari, N., Bhan, M. K., Sazawal, S., Clemens, J. D., Bhatnagar, S., Khoshoo, V.
To determine the effect of nutritional state on persistent diarrhoea a case-control study was carried out on 756 children followed up prospectively for 18 months. Children who developed persistent...
Ray, K, Embleton, M J, Jailkhani, B L, Bhan, M K, Kumar, R
We have prepared human recombinant antibody molecules against the glycoprotein antigen of the rabies virus (GPRV) based on the single chain variable fragment (scFv) format. Anti-GPRV scFvs were...
Ray, Pratima, Sharma, S., Agarwal, R. K., Longmei, K., Gentsch, J. R., Paul, V. K., ...
Rotavirus genotype G12 strains were detected for the first time among newborns with asymptomatic rotavirus infection (74% of 39 rotavirus strains isolated from the infected infants were genotype G12)...
Emergence of G12 Rotavirus Strains in Delhi, India, in 2000 to 2007▿
Sharma, S., Ray, P., Gentsch, J. R., Glass, R. I., Kalra, V., Bhan, M. K.
The prospect that rotavirus diarrhea in children may soon be prevented by vaccines has placed a new priority on understanding the diversity of rotavirus strains and the mechanism by which these...
Bhandari, N., Bhan, M. K., Sazawal, S.
OBJECTIVE--To assess the impact of vitamin A supplementation on morbidity from acute respiratory tract infections and diarrhoea. DESIGN--Double blind randomised placebo controlled field trial....
Clinical trials of improved oral rehydration salt formulations: a review.
Bhan, M. K., Mahalanabis, D., Fontaine, O., Pierce, N. F.
Reviewed are all the published clinical trials of glycine-based oral rehydration salts (ORS), L-alanine-based ORS, L-glutamine-based ORS, maltodextrin-based ORS, and rice-based ORS, as well as the...
Descriptive epidemiology of persistent diarrhoea among young children in rural northern India.
Bhan, M. K., Bhandari, N., Sazawal, S., Clemens, J., Raj, P., Levine, M. M., ...
In order to determine the descriptive epidemiology of persistent diarrhoea in rural northern India, a cohort of 963 children aged 0-71 months was followed prospectively for 12 months through weekly...