10th International Conference On Accelerator Mass Spectrometry (2005)
Knezovich, J, Brown, T, Buchholz, B, Finkel, R, Guilderson, T, Kashgarian, M, ...
Ziesche, R, Roth, M, Papakonstantinou, E, Nauck, M, Hörl, W H, Kashgarian, M, ...
Growing evidence suggests that cytokine expression is influenced by locally produced mediators, thus modifying the pluripotential effects of cytokines toward a tissue-specific inflammatory reaction....
Zahler, R, Brines, M, Kashgarian, M, Benz, E J, Gilmore-Hebert, M
The sodium pump is crucial for the function of the heart and of the cardiac conduction system, which initiates the heartbeat. The alpha (catalytic) subunit of this pump has three isoforms; the alpha...
Functional expression and segmental localization of rat colonic K-adenosine triphosphatase.
Lee, J, Rajendran, V M, Mann, A S, Kashgarian, M, Binder, H J
A putative cDNA for the colonic K-ATPase has recently been cloned (Crowson, M.S., and G. E. Shull. 1992. J. Biol. Chem. 267:13740-13748). Considerable evidence exists that there are two K-ATPases and...
Soifer, N E, Van Why, S K, Ganz, M B, Kashgarian, M, Siegel, N J, Stewart, A F
Parathyroid hormone-related protein (PTHrP) is widely expressed in normal adult and fetal tissues, where it acts in an autocrine/paracrine fashion, stimulates growth and differentiation, and shares...
Van Why, S K, Mann, A S, Thulin, G, Zhu, X H, Kashgarian, M, Siegel, N J
Renal ischemia results in both a profound fall in cellular ATP and a rapid induction of the 70 kD heat-shock protein family, HSP-70. The present studies examined the relationship between cellular ATP...
Transport defects of rabbit medullary thick ascending limb cells in obstructive nephropathy.
Hwang, S J, Haas, M, Harris, H W, Silva, P, Yalla, S, Sullivan, M R, ...
To characterize the sodium transport defect responsible for salt wasting in obstructive nephropathy, the major sodium transporters in the medullary thick ascending limb (mTAL), the apical Na-K-2Cl...
Stromski, M E, Van Waarde, A, Avison, M J, Thulin, G, Gaudio, K M, Kashgarian, M, ...
The concentrations of renal ATP have been measured by 31P-nuclear magnetic resonance (NMR) before, during, and after bilateral renal artery occlusion. Using in vivo NMR, the initial postischemic...
Ziesche, R, Roth, M, Papakonstantinou, E, Nauck, M, Hörl, W H, Kashgarian, M, ...
Growing evidence suggests that cytokine expression is influenced by locally produced mediators, thus modifying the pluripotential effects of cytokines toward a tissue-specific inflammatory reaction....
Zahler, R, Brines, M, Kashgarian, M, Benz, E J, Gilmore-Hebert, M
The sodium pump is crucial for the function of the heart and of the cardiac conduction system, which initiates the heartbeat. The alpha (catalytic) subunit of this pump has three isoforms; the alpha...
Functional expression and segmental localization of rat colonic K-adenosine triphosphatase.
Lee, J, Rajendran, V M, Mann, A S, Kashgarian, M, Binder, H J
A putative cDNA for the colonic K-ATPase has recently been cloned (Crowson, M.S., and G. E. Shull. 1992. J. Biol. Chem. 267:13740-13748). Considerable evidence exists that there are two K-ATPases and...
Soifer, N E, Van Why, S K, Ganz, M B, Kashgarian, M, Siegel, N J, Stewart, A F
Parathyroid hormone-related protein (PTHrP) is widely expressed in normal adult and fetal tissues, where it acts in an autocrine/paracrine fashion, stimulates growth and differentiation, and shares...
Van Why, S K, Mann, A S, Thulin, G, Zhu, X H, Kashgarian, M, Siegel, N J
Renal ischemia results in both a profound fall in cellular ATP and a rapid induction of the 70 kD heat-shock protein family, HSP-70. The present studies examined the relationship between cellular ATP...
Transport defects of rabbit medullary thick ascending limb cells in obstructive nephropathy.
Hwang, S J, Haas, M, Harris, H W, Silva, P, Yalla, S, Sullivan, M R, ...
To characterize the sodium transport defect responsible for salt wasting in obstructive nephropathy, the major sodium transporters in the medullary thick ascending limb (mTAL), the apical Na-K-2Cl...
Stromski, M E, Van Waarde, A, Avison, M J, Thulin, G, Gaudio, K M, Kashgarian, M, ...
The concentrations of renal ATP have been measured by 31P-nuclear magnetic resonance (NMR) before, during, and after bilateral renal artery occlusion. Using in vivo NMR, the initial postischemic...
Askenase, P W, Debernardo, R, Tauben, D, Kashgarian, M
Many delayed-type reactions contain large infiltrates of basophils whose function is unknown. We have studied these cutaneous basophil hypersensitivity (CBH) reactions in guinea-pigs to ascertain...
Paul, L. C., Muralidharan, J., Muzaffar, S. A., Manting, E. H., Valentin, J. F., De Heer, E., ...
Antibodies or cell-mediated immunity can cause chronic rejection of vascularized organ grafts, but the nature and specificity of the antigen(s) involved has remained elusive. We have previously...
Formation of extracellular matrix by cultured rat mesangial cells.
Ishimura, E., Sterzel, R. B., Budde, K., Kashgarian, M.
Formation of extracellular matrix (ECM) by mesangial cells (MCs) contributes to progressive glomerulosclerosis. The authors investigated the production and distribution of ECM constituents by...
Mesangial cell-matrix interactions. Effects on mesangial cell growth and cytokine secretion.
Ruef, C., Kashgarian, M., Coleman, D. L.
Glomerulonephritis (GN) results in proliferation of mesangial cells (MC), infiltration of inflammatory cells, and accumulation of extracellular matrix (ECM) proteins in the mesangium. Locally...
Marti, H. P., Lee, L., Kashgarian, M., Lovett, D. H.
Transforming growth factor-beta 1 (TGF-beta 1) is generally considered to exert positive effects on the accumulation of extracellular matrices. These occur as the net result of enhanced matrix...
Lyme arthritis. Spirochetes found in synovial microangiopathic lesions.
Johnston, Y. E., Duray, P. H., Steere, A. C., Kashgarian, M., Buza, J., Malawista, S. E., ...
In 17 patients with Lyme disease, synovial specimens, obtained by synovectomy or needle biopsy, showed nonspecific villous hypertrophy, synovial cell hyperplasia, prominent microvasculature,...
No aggravation of the course of experimental glomerulonephritis in spontaneously hypertensive rats.
Stein, H. D., Sterzel, R. B., Hunt, J. D., Pabst, R., Kashgarian, M.
Functional and morphologic glomerular alterations induced by antiglomerular basement membrane (anti-GBM) nephritis were investigated in spontaneously hypertensive rats (SHR) and normotensive Wistar...
Sterzel, R. B., Lovett, D. H., Foellmer, H. G., Perfetto, M., Biemesderfer, D., Kashgarian, M.
To examine the capability of glomerular mesangial cells (MCs) to produce extracellular matrix, the authors studied MCs in culture by light and electron microscopy as well as immunocytochemistry. MCs...
Lysosomal enzymes in glomerular cells of the rat.
Lovett, D. H., Ryan, J. L., Kashgarian, M., Sterzel, R. B.
Whole isolated rat glomeruli (WG) were incubated with bacterial collagenase to separate epithelial cells (EC) from the cores of glomerular tufts (GC), which consisted of mesangial and endothelial...
Accelerated cellular recovery after an ischemic renal injury.
Gaudio, K. M., Ardito, T. A., Reilly, H. F., Kashgarian, M., Siegel, N. J.
To determine the mode of action of the beneficial effect of adenosine triphosphate (ATP)-MgCl2, recovery of microinjected inulin, proximal tubular pressure (PTP), and cellular damage as quantitated...