Campbell, A P, Merrett, M N, Kettlewell, M, Mortensen, N J, Jewell, D P
AIMS--To investigate colonic metaplasia of goblet and columnar epithelial cells in ileal pouch mucosa; to correlate this with the degree of morphological and inflammatory change; and to assess...
Crypt cell proliferation and HLA-DR expression in pelvic ileal pouches.
De Silva, H J, Gatter, K C, Millard, P R, Kettlewell, M, Mortensen, N J, Jewell, D P
To investigate the nature of the morphological changes that occur in ileal pouches, 26 biopsy specimens from patients with functioning ileo-anal pouches (eight with pouchitis) were studied. Normal...
Campbell, A P, Merrett, M N, Kettlewell, M, Mortensen, N J, Jewell, D P
AIMS--To investigate colonic metaplasia of goblet and columnar epithelial cells in ileal pouch mucosa; to correlate this with the degree of morphological and inflammatory change; and to assess...
Crypt cell proliferation and HLA-DR expression in pelvic ileal pouches.
De Silva, H J, Gatter, K C, Millard, P R, Kettlewell, M, Mortensen, N J, Jewell, D P
To investigate the nature of the morphological changes that occur in ileal pouches, 26 biopsy specimens from patients with functioning ileo-anal pouches (eight with pouchitis) were studied. Normal...
Cap polyposis--an unusual cause of diarrhoea.
Campbell, A P, Cobb, C A, Chapman, R W, Kettlewell, M, Hoang, P, Haot, B J, ...
'Cap polyposis' is a poorly recognised condition with distinct clinical, sigmoidoscopic, and pathological features that may be confused with other inflammatory conditions of the large intestine...
Mucosal characteristics of pelvic ileal pouches.
De Silva, H J, Millard, P R, Kettlewell, M, Mortensen, N J, Prince, C, Jewell, D P
This study aimed to investigate the degree of colonic metaplasia in ileo - anal pouches. Biopsy specimens from 25 patients with functioning pouches, eight of whom had pouchitis, were studied using...
Lymphocyte and macrophage subpopulations in pelvic ileal pouches.
De Silva, H J, Jones, M, Prince, C, Kettlewell, M, Mortensen, N J, Jewell, D P
This study aimed to characterise the mucosal cellular infiltrate in ileal reservoirs with and without pouchitis (reservoir ileitis). Intraepithelial lymphocyte counts were performed in biopsy...
Effects of the faecal stream and stasis on the ileal pouch mucosa.
De Silva, H J, Millard, P R, Soper, N, Kettlewell, M, Mortensen, N, Jewell, D P
This study aimed to investigate the effects of the faecal stream and stasis on the mucosa of ileal pouches. Nine patients were followed up. Two pouch biopsy specimens were obtained from each at the...
Smoking may prevent pouchitis in patients with restorative proctocolectomy for ulcerative colitis.
Merrett, M N, Mortensen, N, Kettlewell, M, Jewell, D O
Epidemiological studies have shown an increased risk of ulcerative colitis (UC) in non-smokers and particularly recent ex-smokers. Patients with UC have an increased risk of pouchitis following ileal...
The complications of intravenous Corynebacterium parvum infusion.
Gill, P G, Morris, P J, Kettlewell, M
100 intravenous infusions of Corynebacterium parvum were given to thirty-six patients at a dose of 5 mg/m2. Fever and rigors occurred in all patients but these acute side effects were acceptable to...
Effect of digoxin on human red blood cell electrolytes
Kettlewell, M., Nowers, A., White, R.
Red blood cell electrolytes were measured during 48 h after administration of digoxin to twelve patients. The concentrations of some red cell electrolytes changed: sodium increased while potassium...
Dennison, A. R., Ball, M., Crowe, P. J., White, K., Hands, L., Watkins, R. M., ...
In order to test the hypothesis that medium chain triglycerides (MCT's) are a safe and potentially superior energy source during parenteral nutrition 13 patients were entered into a randomised cross...