Head, J., Ferrie, J.E., Alexanderson, K., Westerlund, H., Vahtera, J., Kivimäki, M.
Objective: To investigate whether knowing the diagnosis for sickness absence improves prediction of mortality. Design: Prospective cohort study established in 1985-8. Sickness absence records...
Gimeno, D., Ferrie, J.E., Elovainio, M., Pulkki-Raback, L., Keltikangas-Jarvinen, L., Eklund, C., ...
Background: It is unclear when in the life course do social inequalities in inflammation emerge. We examined whether the association between socioeconomic position (SEP) and C-reactive protein (CRP)...
Singh-Manoux, A., Britton, A., Kivimäki, M., Guéguen, A., Halcox, J., Marmot, M.
Background: Common carotid artery intima-media thickness (IMT) is a measure of generalized atherosclerosis and has been shown to be associated with cognitive function. We examine two questions: does...
Vaananen, A., Kumpulainen, R., Kevin, M.V., Ala-Mursula, L., Kouvonen, A., Kivimäki, M., ...
This study examined the previously unexplored occupational grade-specific relationships of domestic responsibilities, the age of children, and work-family spillover, with registered sickness absence...
Kivimäki, M., Theorell, T., Westerlund, H., Vahtera, J., Alfredsson, L.
OBJECTIVE: Evidence on the association between job strain and ischaemic disease is mixed. This study examined whether including older age individuals in a cohort used to assess job strain attenuates...
Virtanen, M., Koskinen, S., Kivimäki, M., Honkonen, T., Vahtera, J., Ahola, K., ...
OBJECTIVES: To examine the contribution of non-work and work factors to the association between income and DSM-IV depressive and anxiety disorders in a working population. METHODS: A representative...
Kronholm, E., Partonen, T., Laatikainen, T., Peltonen, M., Harma, M., Hublin, C., ...
A hypothesis concerning habitual sleep reduction and its adverse consequences among general population in modern societies has received wide publicity in the mass media, although scientific evidence...
Eklund, C, Kivimäki, M, Islam, M.S., Juonala, M, Kähönen, M, Marniemi, J, ...
Although C-reactive protein (CRP) is known to predict cardiovascular events, its status as a causal risk factor is still controversial. CRP gene single nucleotide polymorphisms (SNPs) have been shown...
Keltikangas-Järvinen, L., Puttonen, S., Kivimäki, M., Elovainio, M., Pulkki-Råback, L., Koivu, M., ...
We examined a modifying role of 5HT1A and 5HT2A receptors in the relation between childhood difficult temperament and adulthood hostility in 729 subjects derived from a population-based sample....
Oksanen, T., Kouvonen, A., Kivimäki, M., Pentti, J., Virtanen, M., Linna, A., ...
The majority of previous research on social capital and health is limited to social capital in residential neighborhoods and communities. Using data from the Finnish 10-Town study we examined social...
Ahola, K., Kivimäki, M., Honkonen, T., Virtanen, M., Koskinen, S., Vahtera, J., ...
OBJECTIVE: Occupational burnout is a common problem in working populations, but its association with sickness absence is poorly understood. The contribution of occupational burnout to medically...
Does personality explain social inequalities in mortality? The French GAZEL cohort study (2008)
Nabi, H., Kivimäki, M., Marmot, M.G., Ferrie, J., Zins, M., Ducimetiere, P., ...
BACKGROUND: The 'indirect-selection' hypothesis proposes that some quality of the individual, a personality characteristic or intelligence, leads to both socioeconomic position (SEP) and health. We...
Batty, G.D., Kivimäki, M., Gray, L., Smith, G.D., Marmot, M.G., Shipley, M.J.
BACKGROUND: The relation between cigarette smoking and several malignancies is still unclear. We examined the association of cigarette smoking with death attributed to 15 cancer sites, 7 of which are...
Work stress and new-onset migraine in a female employee population (2008)
Mäki, K., Vahtera, J., Virtanen, M., Elovainio, M., Keltikangas-Järvinen, L., Kivimäki, M.
This prospective cohort study examined whether work stress, as indicated by the job strain model and the effort–reward imbalance model, predicts new-onset migraine among 19 469 female employees...
Liukkonen, V., Virtanen, P., Kivimäki, M., Pentti, J., Vahtera, J.
Background We studied whether health resources, measured as sense of coherence (SOC), are associated with participation in a follow-up survey among permanent and non-permanent employees who responded...
Kivimäki, M., Ferrie, J.E., Shipley, M.J., Vahtera, J., Singh-Manoux, A., Marmot, M.G., ...
Background: High sickness absence is associated with poor health status, but it is not known whether low levels of sickness absence among people with poor health predict future health improvement....
Lund, T., Kivimäki, M., Labriola, M., Villadsen, E., Christensen, K.B.
Objectives: The aim of this study was to examine duration of sickness absence as a risk marker for future disability pension among all private sector employees in Denmark 1998–2004. Methods: All...
Low organisational justice and heavy drinking: a prospective cohort study (2008)
Kouvonen, A., Kivimäki, M., Elovainio, M., Väänänen, A., De Vogli, R., Heponiemi, T., ...
Objectives: To investigate whether low perceived organisational injustice predicts heavy drinking among employees. Methods: Data from a prospective occupational cohort study, the 10-Town Study, on 15...
Hintsa, T., Kivimäki, M., Elovainio, M., Vahtera, J., Hintsanen, M., Viikari, J.S.A., ...
Objectives. Most previous studies of job strain and cardiovascular risk have been limited to adult data. It remains unclear whether this association might be explained by factors present already...
Christensen, K.B., Labriola, M., Lund, T., Kivimäki, M.
Objectives: To identify differences in risk of sickness absence between socioeconomic groups, and to examine to what extent these differences can be explained by health behaviour and work environment...
Kivimäki, M., Ferrie, J.E., Shipley, M., Gimeno, D., Elovainio, M., De Vogli, R., ...
Objective: To examine whether lower BP mediates the inverse association between organizational justice and incident coronary heart disease (CHD). Previous studies suggest lower blood pressure (BP)...
Suoyrjö, H., Hinkka, K., Oksanen, T., Kivimäki, M., Klaukka, T., Pentti, J., ...
Objective: To determine the effects of multidisciplinary in-patient rehabilitation for chronic back or neck pain on sickness absences and analgesic purchases. Design: A prospective observational...
Liability to anxiety and severe life events as predictors of new-onset sleep disturbances (2007)
Vahtera, J., Kivimäki, M., Hublin, C., Korkeila, K., Suominen, S., Paunio, T., ...
Study Objectives: This study examined the effects of liability to anxiety and stressful life events on the onset of sleep disturbances. Design: A 5-year longitudinal observational cohort study....
Kivimäki, M., Head, J., Ferrie, J.E., Shipley, M.J., Steptoe, A., Vahtera, J., ...
Background Hypertension is assumed to be one of the mechanisms through which job strain (a combination of high work demands and low job control) increases coronary heart-disease risk. However, direct...
Kivimäki, M., Lawlor, D.A., Smith, G.D., Elovainio, M., Jokela, M., Keltikangas-Järvinen, L., ...
Background: According to the fetal overnutrition hypothesis, intrauterine influences of maternal obesity increased lifelong obesity risk in the offspring. If the hypothesis is true, then the...
Hintsanen, M., Elovainio, M., Puttonen, S., Kivimäki, M., Koskinen, T., Raitakari, O.T., ...
Background: Work stress indicated by effort-reward imbalance is hypothesized to cause autonomic arousal, which, if prolonged or frequent, could contribute to cardiovascular pathology. However, only...
Kivimäki, M., Lawlor, D.A., Davey Smith, G., Eklund, C., Hurme, M., Lehtimäki, T., ...
Genetic association studies have used variants in the C-reactive protein (CRP) gene to estimate causal effects of lifelong circulating CRP levels on disease endpoints. However, the extent to which...
Head, J., Kivimäki, M., Siegrist, J., Ferrie, J.E., Vahtera, J., Shipley, M.J., ...
Objectives Sickness absence is a major occupational health problem, but evidence for associations between potentially modifiable psychosocial work factors and sickness absence is still scarce. We...
Hurme, M., Kivimäki, M., Pertovaara, M., Lehtimäki, T., Karhunen, P.J., Jylhä, M., ...
Chronic low-grade inflammation is involved in the pathogenesis of many disease conditions in humans and it is frequently quantified by measuring the blood concentration of C-reactive protein (CRP)....
Keltikangas-Järvinen, L., Elovainio, M., Kivimäki, M., Raitakari, O.T., Viikari, J.S.A., Lehtimäki, T.
OBJECTIVE. Low birth weight is suggested to be a risk factor for a wide variety of negative outcomes, including low educational attainment, but the role of cognition-related genetic influences on...
Heponiemi, T., Elovainio, M., Manderbacka, K., Kivimäki, M., Keskimäki, I.
Objective: The aim of this longitudinal study was to examine (a) the causal effect of unemployment 1990–1997 on health 1998–2001 (in-patient periods) and (b) the selection effect of health...
Kivimäki, M., Vahtera, J., Elovainio, M., Virtanen, M., Siegrist, J.
Objective: Effort-reward imbalance at work is an established psychosocial risk factor but there are also newer conceptualisations, such as procedural injustice (decisions at work lack consistency,...
Interventions in relation to occupational burnout: the population-based Health 2000 study (2007)
Ahola, K., Honkonen, T., Virtanen, M., Kivimäki, M., Isometsä, E., Aromaa, A., ...
Abstract: Objective: To study participation in occupational and individual-focused interventions in relation to burnout. Methods: We used data from a questionnaire, structured interview, national...
Suominen, S., Vahtera, J., Korkeila, K., Helenius, H., Kivimäki, M., Koskenvuo, M.
OBJECTIVE: To examine job strain, adverse life events, and their co-occurrence as predictors of sickness absence. METHODS: Random sample-based mail survey data on 1806 Finns in gainful employment...
Job strain and psychologic distress influence on sickness absence among Finnish employees (2007)
Virtanen, M., Vahtera, J., Pentti, J., Honkonen, T., Elovainio, M., Kivimäki, M.
Background: Work stress is a recognized risk factor for mental health disorders, but it is not known whether work stress is associated with the morbidity among individuals with psychologic distress....
Body mass index in adolescence and number of children in adulthood (2007)
Jokela, M., Kivimäki, M., Elovainio, M., Viikari, J., Raitakari, O.T., Keltikangas-Järvinen, L.
Background: Body weight is associated with reproduction and related behaviors, but it is unknown whether it has significance for fertility differences in the general population. We examined whether...
Increased sickness absence in diabetic employees: what is the role of co-morbid conditions? (2007)
Kivimäki, M., Vahtera, J., Pentti, J., Virtanen, M., Elovainio, M., Hemingway, H.
AIMS: Diabetes is thought to be associated with increased risk of sickness absence in working populations. We examined the contribution of co-morbidity to this association. METHODS: Records of...
Elovainio, M., Kivimäki, M., Ek, E., Vahtera, J., Honkonen, T., Taanila, A., ...
This study examined the role of pre-employment factors, such as maternal antenatal depression, low birth weight, childhood socioeconomic position, early adolescence health risk behaviours and...
Association of impulsivity with sleep duration and insomnia in an employee population (2007)
Granö, N., Keltikangas-Järvinen, L., Kouvonen, A., Puttonen, S., Virtanen, M., Vahtera, J., ...
Clinical studies have linked impulsivity and insomnia in patients, but little is known about this association in non-clinical settings. This study examined whether impulsive temperament is associated...
Hintsanen, M., Elovainio, M., Puttonen, S., Kivimäki, M., Raitakari, O.T., Lehtimaki, T., ...
Background: Although it is known that a given level of strain does not induce a corresponding CHD risk in all individuals, factors that predict groups at risk have remained unclear. Neuregulin-1...
BMI, obesity, and sickness absence in the Whitehall II study (2007)
Ferrie, J.E., Head, J., Shipley, M.J., Vahtera, J., Marmot, M.G., Kivimäki, M.
OBJECTIVE: To study BMI and change in BMI from age 25 as predictors of sickness absence. RESEARCH METHODS AND PROCEDURES: Data were collected from 2564 women and 5853 men, who were British civil...
Outcome of stable angina in a working population: the burden of sickness absence (2007)
Hemingway, H., Vahtera, J., Virtanen, M., Pentti, J., Kivimäki, M.
BACKGROUND: The decline in acute event rates among patients with stable angina emphasizes the need for outcome events that are commonly experienced, externally observed and sensitive to changing...
Hintsa, T., Kivimäki, M., Elovainio, M., Hintsanen, M., Pulkki-Råback, L., Keltikangas-Järvinen, L.
OBJECTIVE: We prospectively examined whether preemployment family factors predict adulthood work stress manifested as effort-reward imbalance (ERI). METHODS: The study sample comprised 746...
Keltikangas-Järvinen, L., Puttonen, S., Kivimäki, M., Elovainio, M., Rontu, R., Lehtimäki, T.
We conducted a series of tests to determine whether there is any association between tryptophan hydroxylase 1 (TPH1) and temperament in adulthood. In addition to testing for main effects, we...
Kivimäki, M., Lawlor, D.A., Davey Smith, G., Kouvonen, A., Virtanen, M., Elovainio, M., ...
OBJECTIVES: We examined the associations between socioeconomic position, co-occurrence of behavior-related risk factors, and the effect of these factors on the relative and absolute socioeconomic...
Virtanen, M., Kivimäki, M., Kouvonen, A., Elovainio, M., Linna, A., Oksanen, T., ...
Social environments, like neighbourhoods, are increasingly recognised as determinants of health. While several studies have reported an association of low neighbourhood socio-economic status with...
Suoyrjö, H., Hinkka, K., Kivimäki, M., Klaukka, T., Pentti, J., Vahtera, J.
OBJECTIVE: To study the allocation of rehabilitation measures provided by the Finnish Social Insurance Institution in relation to the characteristics and health status of rehabilitants. DESIGN: A...
Impulsivity as a predictor of newly diagnosed depression (2007)
Granö, N., Keltikangas-Järvinen, L., Kouvonen, A., Virtanen, M., Elovainio, M., Vahtera, J., ...
Depression is a severe mental disorder, whose onset has been related to environmental, genetic and personality factors. This study examined the association between impulsivity and incidence of...
Feldt, T., Lintula, H., Suominen, S., Koskenvuo, M., Vahtera, J., Kivimäki, M.
Study objective: To investigate whether the structure of Antonovsky’s [Unraveling the Mystery of Health. How People Manage Stress and Stay Well. San Francisco: Jossey-Bass, 1987] 13-item Sense of...
Jokela, M., Keltikangas-Järvinen, L., Kivimäki, M., Puttonen, S., Elovainio, M., Rontu, R., ...
BACKGROUND: Gene-environment interactions are assumed to be involved in the development of depression. OBJECTIVE: To determine whether the serotonin receptor 2A (HTR2A) gene moderates the association...
Kivimäki, M., Hintsanen, M., Keltikangas-Järvinen, L., Elovainio, M., Pulkki-Råback, L., Vahtera, J., ...
We examined whether preemployment influences confounded the association between job strain and atherosclerosis. We assessed biological, familial, and socioeconomic risk factors of coronary heart...
Social inequalities in antidepressant treatment and mortality: a longitudinal register study (2007)
Kivimäki, M., Gunnell, D., Lawlor, D.A., Davey Smith, G., Pentti, J., Virtanen, M., ...
Background. Despite an increased prevalence of depression among people of low socio-economic position, it remains unclear whether their treatment with antidepressants appropriately matches their...
Work stress, mental health and antidepressant medication findings from the Health 2000 study (2007)
Virtanen, M., Honkonen, T., Kivimäki, M., Ahola, K., Vahtera, J., Aromaa, A., ...
Background: Population-based studies on the association between work stress and mental disorders are scarce, and it is not known whether work stress predicts mental disorders requiring treatment....
Rauhala, A., Kivimäki, M., Fagerström, L., Elovainio, M., Virtanen, M., Vahtera, J., ...
Aim. This paper reports a study examining whether nurses’ work overload is associated with increased sick leave and quantifying the loss of working days from work overload. Background. The RAFAELA...
Kivimäki, M., Honkonen, T., Wahlbeck, K., Elovainio, M., Pentti, J., Klaukka, T., ...
Objective: Organisational downsizing is common in modern work life, but its effect on employees’ mental health is not known. The authors examined whether working in downsizing organisations...
Increased absence due to sickness among employees with fibromyalgia (2007)
Kivimäki, M., Leino-Arjas, P., Kaila-Kangas, L., Virtanen, M., Elovainio, M., Puttonen, S., ...
Background: Little is known about the effect of fibromyalgia on absence due to sickness in working populations. Objective: To examine the risk of absence due to sickness among employees with...