M. L. Handel

A Pilot Randomized Trial Comparing CD-34Selected Versus Unmanipulated Hemopoietic Stem Cell Transplantation for Severe, Refractory Rheumatoid Arthritis (2002)

Moore, J., Brooks, P. M., Milliken, S., Biggs, J.S., Ma, D., Handel, M. L., ...

Objective. Evidence from animal studies, case reports, and phase I studies suggests that hemopoietic stem cell transplantation (HSCT) can be effective in the treatment of rheumatoid arthritis (RA)....

Connective tissue and bone disorders (2000)

Day, R., Quinn, D., Williams, K., Handel, M. L., Brooks, P. M.

Disease-modifying anti-rheumatic drugs (1999)

Bachmeier, C., Handel, M. L., Conaghan, P. G., Williams, K. M., Graham, G. G., Brooks, P. M., ...

Inhibition of AP-1 binding and transcription by gold and selenium involving conserved cysteine residues in Jun and Fos.

Handel, M L, Watts, C K, DeFazio, A, Day, R O, Sutherland, R L

Gold(I) salts and selenite, which have diverse therapeutic and biological effects, are noted for their reactivity with thiols. Since the binding of Jun-Jun and Jun-Fos dimers to the AP-1 DNA binding...

Inhibition of AP-1 binding and transcription by gold and selenium involving conserved cysteine residues in Jun and Fos.

Handel, M L, Watts, C K, DeFazio, A, Day, R O, Sutherland, R L

Gold(I) salts and selenite, which have diverse therapeutic and biological effects, are noted for their reactivity with thiols. Since the binding of Jun-Jun and Jun-Fos dimers to the AP-1 DNA binding...

Multinucleated cells in pigmented villonodular synovitis and giant cell tumor of tendon sheath express features of osteoclasts.

Darling, J. M., Goldring, S. R., Harada, Y., Handel, M. L., Glowacki, J., Gravallese, E. M.

Pigmented villonodular synovitis (PVNS) and the histologically related lesion giant cell tumor of tendon sheath (GCTTS) are idiopathic, proliferative lesions that can induce osteolysis and formation...