M. L. Morningstar

X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine.

Lipscomb, L A, Peek, M E, Morningstar, M L, Verghis, S M, Miller, E M, Rich, A, ...

We have determined the x-ray structure of a DNA fragment containing 7,8-dihydro-8-oxoguanine (G(O)). The structure of the duplex form of d(CCAGOCGCTGG) has been determined to 1.6-A resolution. The...

Adduct detection by acylation with [35S]methionine: analysis of DNA adducts of 4-aminobiphenyl.

Sheabar, F Z, Morningstar, M L, Wogan, G N

Reaction of synthetic N-(2'-deoxyguanosin-8-yl)-4-aminobiphenyl (dGuo-8-ABP) with t-butoxycarbonyl-L-[35S]methionine, N-hydroxysuccinimidyl ester (35S-labeled TBM-NHS), under optimized conditions...

Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coli.

Wood, M L, Esteve, A, Morningstar, M L, Kuziemko, G M, Essigmann, J M

A single 7,8-dihydro-8-oxoguanine (G8-OXO; 8-hydroxyguanine) adduct in the lacZ alpha gene of bacteriophage M13 DNA induces a targeted G-->T transversion after replication in Escherichia coli...

X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine.

Lipscomb, L A, Peek, M E, Morningstar, M L, Verghis, S M, Miller, E M, Rich, A, ...

We have determined the x-ray structure of a DNA fragment containing 7,8-dihydro-8-oxoguanine (G(O)). The structure of the duplex form of d(CCAGOCGCTGG) has been determined to 1.6-A resolution. The...

Adduct detection by acylation with [35S]methionine: analysis of DNA adducts of 4-aminobiphenyl.

Sheabar, F Z, Morningstar, M L, Wogan, G N

Reaction of synthetic N-(2'-deoxyguanosin-8-yl)-4-aminobiphenyl (dGuo-8-ABP) with t-butoxycarbonyl-L-[35S]methionine, N-hydroxysuccinimidyl ester (35S-labeled TBM-NHS), under optimized conditions...

Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coli.

Wood, M L, Esteve, A, Morningstar, M L, Kuziemko, G M, Essigmann, J M

A single 7,8-dihydro-8-oxoguanine (G8-OXO; 8-hydroxyguanine) adduct in the lacZ alpha gene of bacteriophage M13 DNA induces a targeted G-->T transversion after replication in Escherichia coli...