Day, BW, Smith, FM, Chen, K, McCarron, JK, Herath, NI, Lackmann, M, ...
There is an urgent need for high purity, single chain, fully functional Eph/ephrin membrane proteins. This report outlines the pTIg-BOS-Fc vector and purification approach resulting in rapid...
Day, BW, Smith, FM, Chen, K, McCarron, JK, Herath, NI, Lackmann, M, ...
There is an urgent need for high purity, single chain, fully functional Eph/ephrin membrane proteins. This report outlines the pTIg-BOS-Fc vector and purification approach resulting in rapid...
Vearing, C, Lee, FT, Wimmer-Kleikamp, S, Spirkoska, V, To, C, Stylianou, C, ...
The Eph receptor tyrosine kinases and their membrane-bound ephrin ligands form a unique cell-cell contact-mediated system for controlling cell localization and organization. Their high expression in...
Day, B, To, C, Himanen, JP, Smith, FM, Nikolov, DB, Boyd, AW, ...
Eph receptor tyrosine kinases (Ephs) function as molecular relays that interact with cell surface-bound ephrin ligands to direct the position of migrating cells. Structural studies revealed that,...
Vearing, C, Lee, FT, Wimmer-Kleikamp, S, Spirkoska, V, To, C, Stylianou, C, ...
The Eph receptor tyrosine kinases and their membrane-bound ephrin ligands form a unique cell-cell contact-mediated system for controlling cell localization and organization. Their high expression in...
Day, B, To, C, Himanen, JP, Smith, FM, Nikolov, DB, Boyd, AW, ...
Eph receptor tyrosine kinases (Ephs) function as molecular relays that interact with cell surface-bound ephrin ligands to direct the position of migrating cells. Structural studies revealed that,...
Dissecting the EphA3/ephrin-A5 interactions using a novel functional mutagenesis screen (2004)
Smith, F. M., Vearing, C., Lackmann, M., Treutlein, H., Himanen, J., Chen, K., ...
The EphA3 receptor tyrosine kinase preferentially binds ephrin-A5, a member of the corresponding subfamily of membrane-associated ligands. Their interaction regulates critical cell communication...
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling (2004)
Himanen, JP, Chumley, MJ, Lackmann, M, Li, C, Barton, WA, Jeffrey, PD, ...
The interactions between Eph receptor tyrosine kinases and their ephrin ligands regulate cell migration and axon pathfinding. The EphA receptors are generally thought to become activated by ephrin-A...
Dissecting the EphA3/ephrin-A5 interactions using a novel functional mutagenesis screen (2004)
Smith, F. M., Vearing, C., Lackmann, M., Treutlein, H., Himanen, J., Chen, K., ...
The EphA3 receptor tyrosine kinase preferentially binds ephrin-A5, a member of the corresponding subfamily of membrane-associated ligands. Their interaction regulates critical cell communication...
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling (2004)
Himanen, JP, Chumley, MJ, Lackmann, M, Li, C, Barton, WA, Jeffrey, PD, ...
The interactions between Eph receptor tyrosine kinases and their ephrin ligands regulate cell migration and axon pathfinding. The EphA receptors are generally thought to become activated by ephrin-A...
The role of the Eph-ephrin signalling system in the regulation of developmental patterning (2002)
Coulthard, MG, Duffy, S, Down, M, Evans, B, Power, M, Smith, F, ...
The Eph and ephrin system, consisting of fourteen Eph receptor tyrosine kinase proteins and nine ephrin membrane proteins in vertebrates, has been implicated in the regulation of many critical events...
The role of the Eph-ephrin signalling system in the regulation of developmental patterning (2002)
Coulthard, MG, Duffy, S, Down, M, Evans, B, Power, M, Smith, F, ...
The Eph and ephrin system, consisting of fourteen Eph receptor tyrosine kinase proteins and nine ephrin membrane proteins in vertebrates, has been implicated in the regulation of many critical events...
Signals from Eph and Ephrin Proteins: A Developmental Tool Kit (2001)
This was an invited review based on our published work in the area of Eph biology and signalling.
Signals from Eph and Ephrin Proteins: A Developmental Tool Kit (2001)
This was an invited review based on our published work in the area of Eph biology and signalling.
EPH receptors and their ephrin ligands play important roles during early development (1999)
Power, M., Lackmann, M., Oates, A. C., Down, L. M., Boyd, A. W.
An early developmental role for Eph-ephrin interaction during vertebrate gastrulation (1999)
Oates, A. C., Lackmann, M., Power, M. A., Brennan, C., Down, L. M., Do, C., ...
Eph receptor tyrosine kinases (RTK) and their ephrin ligands are involved in the transmission of signals which regulate cytoskeletal organisation and cell migration, and are expressed in spatially...
An early developmental role for Eph-ephrin interaction during vertebrate gastrulation (1999)
Oates, A. C., Lackmann, M., Power, M. A., Brennan, C., Down, L. M., Do, C., ...
Eph receptor tyrosine kinases (RTK) and their ephrin ligands are involved in the transmission of signals which regulate cytoskeletal organisation and cell migration, and are expressed in spatially...
Lackmann, M, Harpur, AG, Oates, AC, Mann, RJ, Gabriel, A, Meutermans, W, ...
The basic framework for the JAK/STAT pathway is well documented. Recruitment of latent cytoplasmic STAT transcription factors to tyrosine phosphorylated docking sites on cytokine receptors and their...
Lackmann, M, Harpur, AG, Oates, AC, Mann, RJ, Gabriel, A, Meutermans, W, ...
The basic framework for the JAK/STAT pathway is well documented. Recruitment of latent cytoplasmic STAT transcription factors to tyrosine phosphorylated docking sites on cytokine receptors and their...
Lackmann, M, Bucci, T, Mann, R J, Kravets, L A, Viney, E, Smith, F, ...
Advances in screening technologies allowing the identification of growth factor receptors solely by virtue of DNA or protein sequence comparison call for novel methods to isolate corresponding ligand...
Ratka, M, Lackmann, M, Ueckermann, C, Karlins, U, Koch, G
The previously described poliovirus-associated protein kinase activity phosphorylates viral proteins VP0 and VP2 as well as exogenous proteins in the presence of Mg2+. In this paper, the effect of...
Lackmann, M, Bucci, T, Mann, R J, Kravets, L A, Viney, E, Smith, F, ...
Advances in screening technologies allowing the identification of growth factor receptors solely by virtue of DNA or protein sequence comparison call for novel methods to isolate corresponding ligand...
Ratka, M, Lackmann, M, Ueckermann, C, Karlins, U, Koch, G
The previously described poliovirus-associated protein kinase activity phosphorylates viral proteins VP0 and VP2 as well as exogenous proteins in the presence of Mg2+. In this paper, the effect of...
Lackmann, M, Harpur, AG, Oates, AC, Mann, RJ, Gabriel, A, Meutermans, W, ...
The basic framework for the JAK/STAT pathway is well documented. Recruitment of latent cytoplasmic STAT transcription factors to tyrosine phosphorylated docking sites on cytokine receptors and their...
Lawrenson, ID, Wimmer-Kleikamp, SH, Lock, P, Schoenwaelder, SM, Down, M, Boyd, AW, ...
Eph receptor tyrosine kinases and ephrins regulate morphogenesis in the developing embryo where they effect adhesion and motility of interacting cells. Although scarcely expressed in adult tissues,...