M. M. Hermans

Differential regulation of distinct types of gap junction channels by similar phosphorylating conditions.

Kwak, B R, Hermans, M M, De Jonge, H R, Lohmann, S M, Jongsma, H J, Chanson, M

Studies on physiological modulation of intercellular communication mediated by protein kinases are often complicated by the fact that cells express multiple gap junction proteins (connexins; Cx)....

Human lysosomal alpha-glucosidase: functional characterization of the glycosylation sites.

Hermans, M M, Wisselaar, H A, Kroos, M A, Oostra, B A, Reuser, A J

N-linked glycosylation is one of the important events in the post-translational modification of human lysosomal alpha-glucosidase. Phosphorylation of mannose residues ensures efficient transport of...

The conservative substitution Asp-645-->Glu in lysosomal alpha-glucosidase affects transport and phosphorylation of the enzyme in an adult patient with glycogen-storage disease type II.

Hermans, M M, De Graaff, E, Kroos, M A, Wisselaar, H A, Willemsen, R, Oostra, B A, ...

Glycogen-storage disease type II (GSDII) is caused by the deficiency of lysosomal alpha-glucosidase (acid maltase). This paper reports on the analysis of the mutant alleles in an American black...

Expression and routeing of human lysosomal alpha-glucosidase in transiently transfected mammalian cells.

Hoefsloot, L H, Willemsen, R, Kroos, M A, Hoogeveen-Westerveld, M, Hermans, M M, Van Der Ploeg, A T, ...

Previously isolated lysosomal alpha-glucosidase cDNA clones were ligated to full-length constructs for expression in vitro and in mammalian cells. One of these constructs (pSHAG1) did not code for...

The African origin of the common mutation in African American patients with glycogen-storage disease type II.

Becker, J A, Vlach, J, Raben, N, Nagaraju, K, Adams, E M, Hermans, M M, ...

Differential regulation of distinct types of gap junction channels by similar phosphorylating conditions.

Kwak, B R, Hermans, M M, De Jonge, H R, Lohmann, S M, Jongsma, H J, Chanson, M

Studies on physiological modulation of intercellular communication mediated by protein kinases are often complicated by the fact that cells express multiple gap junction proteins (connexins; Cx)....

Human lysosomal alpha-glucosidase: functional characterization of the glycosylation sites.

Hermans, M M, Wisselaar, H A, Kroos, M A, Oostra, B A, Reuser, A J

N-linked glycosylation is one of the important events in the post-translational modification of human lysosomal alpha-glucosidase. Phosphorylation of mannose residues ensures efficient transport of...

The conservative substitution Asp-645-->Glu in lysosomal alpha-glucosidase affects transport and phosphorylation of the enzyme in an adult patient with glycogen-storage disease type II.

Hermans, M M, De Graaff, E, Kroos, M A, Wisselaar, H A, Willemsen, R, Oostra, B A, ...

Glycogen-storage disease type II (GSDII) is caused by the deficiency of lysosomal alpha-glucosidase (acid maltase). This paper reports on the analysis of the mutant alleles in an American black...

Expression and routeing of human lysosomal alpha-glucosidase in transiently transfected mammalian cells.

Hoefsloot, L H, Willemsen, R, Kroos, M A, Hoogeveen-Westerveld, M, Hermans, M M, Van Der Ploeg, A T, ...

Previously isolated lysosomal alpha-glucosidase cDNA clones were ligated to full-length constructs for expression in vitro and in mammalian cells. One of these constructs (pSHAG1) did not code for...

The African origin of the common mutation in African American patients with glycogen-storage disease type II.

Becker, J A, Vlach, J, Raben, N, Nagaraju, K, Adams, E M, Hermans, M M, ...

Human alpha-N-acetylgalactosaminidase (alpha-NAGA) deficiency: new mutations and the paradox between genotype and phenotype.

Keulemans, J L, Reuser, A J, Kroos, M A, Willemsen, R, Hermans, M M, Van Den Ouweland, A M, ...

Up to now eight patients with alpha-NAGA deficiency have been described. This includes the newly identified patient reported here who died unexpectedly aged 1 1/2 years of hypoxia during convulsions;...