Shenoy, AR, Srinivas, A, Mahalingam, M, Visweswariah, SS
A number of genes similar to mammalian Class III nucleotide cyclases are found in mycobacteria, and biochemical characterization of some of these proteins has indicated that they code for adenylyl...
The mitogen response of p70/p85 S6 kinase (S6K) parallels that of mitogen-activated protein kinases (MAPK). However, S6K lies on a discrete signaling pathway from MAPK, since the immunosuppressant...
A case against the specificity of "cardiac" troponin-T.
A case of a spurious rise in cardiac troponin-T in an 85 year old Caucasian man with myelodysplastic syndrome and multiple malignancies but with intact cardiac and renal function is reported. The...
The mitogen response of p70/p85 S6 kinase (S6K) parallels that of mitogen-activated protein kinases (MAPK). However, S6K lies on a discrete signaling pathway from MAPK, since the immunosuppressant...
A case against the specificity of "cardiac" troponin-T.
A case of a spurious rise in cardiac troponin-T in an 85 year old Caucasian man with myelodysplastic syndrome and multiple malignancies but with intact cardiac and renal function is reported. The...
Cell cycling in HIV infection: analysis of in vivo activated lymphocytes.
Mahalingam, M, Pozniak, A, McManus, T J, Vergani, D, Peakman, M
Infection with HIV results in increased circulating levels of T lymphocytes expressing phenotypic markers of immune activation. In the present study, using three-colour immunofluorescence, we...
T cell activation and disease severity in HIV infection.
Mahalingam, M, Peakman, M, Davies, E T, Pozniak, A, McManus, T J, Vergani, D
In vitro studies have indicated that T lymphocyte activation may be of importance in the pathogenesis of HIV infection. In order to define the role of immune activation in vivo, we assessed the...
AIDS survival and progression in black Africans living in south London, 1986-1994.
Low, N, Paine, K, Clark, R, Mahalingam, M, Pozniak, A L
OBJECTIVES: To describe the rate of progression to AIDS and survival following AIDS diagnosis in HIV-infected Africans living in London. To identify factors influencing progression and outcome of...