M. Monod

Publication List Details

Period

2004 - 2008

Number

48

Co-Authors

RNA silencing in the dermatophyte Microsporum canis (2007)

Vermout, S, Tabart, J, Baldo, Aline, Monod, M, Losson, Bertrand, Mignon, Bernard

Dermatomycoses caused by Microsporum canis are frequent in domestic animals and easily transmissible to humans. Several proteases secreted by this fungus were identified as potential virulence...

Secreted subtilisin gene family in Trichophyton rubrum (2004)

Jousson, O, Lechenne, B, Bontems, O, Mignon, Bernard, Reichard, U, Barblan, J, ...

Secreted proteases constitute potential virulence factors of dermatophytes. A total of seven genes encoding putative serine proteases of the subtilisin family (SUB) were isolated in Trichophyton...

Multiplication of an ancestral gene encoding secreted fungalysin preceded species differentiation in the dermatophytes Trichophyton and Microsporum (2004)

Jousson, O, Lechenne, B, Bontems, O, Capoccia, S, Mignon, Bernard, Barblan, J, ...

Dermatophytes are human and animal pathogenic fungi which cause cutaneous infections and grow exclusively in the stratum corneum, nails and hair. In a culture medium containing soy proteins as sole...

Production and Characterization of Recombinant Aspergillus fumigatus Cu,Zn Superoxide Dismutase and Its Recognition by Immune Human Sera

Holdom, M. D., Lechenne, B., Hay, R. J., Hamilton, A. J., Monod, M.

The Cu,Zn superoxide dismutase (SOD) of Aspergillus fumigatus has previously been purified and shown to be immunoreactive to the sera of patients with aspergillosis; however, the purification of...

Rapid Detection of Candida albicans in Clinical Samples by DNA Amplification of Common Regions from C. albicans-Secreted Aspartic Proteinase Genes

Flahaut, M., Sanglard, D., Monod, M., Bille, J., Rossier, M.

Laboratory diagnosis based on genomic amplification methods such as PCR may provide an alternative and more sensitive method than conventional culture for the early detection of deep-seated...

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.

Sanglard, D, Kuchler, K, Ischer, F, Pagani, J L, Monod, M, Bille, J

Azole antifungal agents, and especially fluconazole, have been used widely to treat oropharyngeal candidiasis in patients with AIDS. An increasing number of cases of clinical resistance against...

Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.

Sanglard, D, Ischer, F, Monod, M, Bille, J

Some Candida albicans isolates from AIDS patients with oropharyngeal candidiasis are becoming resistant to the azole antifungal agent fluconazole after prolonged treatment with this compound. Most of...

Molecular characterization of the food-borne fungus Neosartorya fischeri (Malloch and Cain).

Girardin, H, Monod, M, Latgé, J P

The food-borne fungus Neosartorya fischeri, which is phenotypically related to the human opportunistic pathogen Aspergillus fumigatus, causes spoilage of heat-processed fruit products. Genomic...

Dipeptidyl-peptidase IV secreted by Aspergillus fumigatus, a fungus pathogenic to humans.

Beauvais, A, Monod, M, Wyniger, J, Debeaupuis, J P, Grouzmann, E, Brakch, N, ...

A dipeptidyl-peptidase IV was purified from the culture medium of the human-pathogenic fungus Aspergillus fumigatus. The enzyme has an apparent molecular mass of 95 kDa and contained approximately 10...

Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.

Hube, B, Sanglard, D, Odds, F C, Hess, D, Monod, M, Schäfer, W, ...

Secreted aspartyl proteinases (Saps), encoded by a gene family with at least nine members (SAP1 to SAP9), are one of the most discussed virulence factors produced by the human pathogen Candida...

A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.

Sanglard, D, Hube, B, Monod, M, Odds, F C, Gow, N A

Secreted aspartyl proteinases (Saps) from Candida albicans are encoded by a multigene family with at least nine members (SAP1 to SAP9) and are considered putative virulence factors important for the...

Cloning and disruption of the antigenic catalase gene of Aspergillus fumigatus.

Calera, J A, Paris, S, Monod, M, Hamilton, A J, Debeaupuis, J P, Diaquin, M, ...

Aspergillus fumigatus possesses two catalases (described as fast and slow on the basis of their electrophoretic mobility). The slow catalase has been recognized as a diagnostic antigen for...

Cloning and analysis of ermG, a new macrolide-lincosamide-streptogramin B resistance element from Bacillus sphaericus.

Monod, M, Mohan, S, Dubnau, D

To analyze the regulation of a newly discovered macrolide-lincosamide-streptogramin B resistance element (ermG) found in a soil isolate of Bacillus sphaericus, we cloned this determinant and obtained...

Sequence and properties of pIM13, a macrolide-lincosamide-streptogramin B resistance plasmid from Bacillus subtilis.

Monod, M, Denoya, C, Dubnau, D

We initiated a study of pIM13, a multicopy, macrolide-lincosamide-streptogramin B (MLS) plasmid first isolated from a strain of Bacillus subtilis and described by Mahler and Halvorson (J. Gen....

Replication properties of pIM13, a naturally occurring plasmid found in Bacillus subtilis, and of its close relative pE5, a plasmid native to Staphylococcus aureus.

Projan, S J, Monod, M, Narayanan, C S, Dubnau, D

A naturally occurring plasmid from Bacillus subtilis, pIM13, codes for constitutively expressed macrolide-lincosamide-streptogramin B (MLS) resistance, is stably maintained at a high copy number, and...

Two different 16S rRNA genes in a mycobacterial strain.

Ninet, B, Monod, M, Emler, S, Pawlowski, J, Metral, C, Rohner, P, ...

Sequencing of the gene coding for 16S rRNA (16S rDNA) is a well-established method used to identify bacteria, particularly mycobacteria. Unique sequences allow identification of a particular genus...

Fluconazole-resistant recurrent oral candidiasis in human immunodeficiency virus-positive patients: persistence of Candida albicans strains with the same genotype.

Millon, L, Manteaux, A, Reboux, G, Drobacheff, C, Monod, M, Barale, T, ...

Thirty human immunodeficiency virus-positive patients carrying Candida albicans in their oropharynx were treated with fluconazole and were monitored for 90 to 570 days. Fluconazole-resistant C....

Isolation and characterization of a secreted metalloprotease of Aspergillus fumigatus.

Monod, M, Paris, S, Sanglard, D, Jaton-Ogay, K, Bille, J, Latgé, J P

A metalloprotease (MEP) secreted by Aspergillus fumigatus was isolated from an alkaline protease-deficient mutant after the fungus was cultivated in the presence of collagen as the sole nitrogen and...

rodletless mutants of Aspergillus fumigatus.

Thau, N, Monod, M, Crestani, B, Rolland, C, Tronchin, G, Latgé, J P, ...

Conidia of Aspergillus fumigatus adhere in vitro to host proteins and cells via the outer cell wall layer. The rodA gene of A. fumigatus was cloned by homology with the rodA gene of Aspergillus...

The yeast acid phosphatase can enter the secretory pathway without its N-terminal signal sequence.

Silve, S, Monod, M, Hinnen, A, Haguenauer-Tsapis, R

The repressible Saccharomyces cerevisiae acid phosphatase (APase) coded by the PHO5 gene is a cell wall glycoprotein that follows the yeast secretory pathway. We used in vitro mutagenesis to...

Identification of the catalytic residues of the first family of beta(1-3)glucanosyltransferases identified in fungi.

Mouyna, I, Monod, M, Fontaine, T, Henrissat, B, Léchenne, B, Latgé, J P

A new family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases (Gelp), recently identified and characterized in the filamentous fungus Aspergillus fumigatus, showed functional...

Candida colonization and subsequent infections in critically ill surgical patients.

Pittet, D, Monod, M, Suter, P M, Frenk, E, Auckenthaler, R

OBJECTIVE. The authors determined the role of Candida colonization in the development of subsequent infection in critically ill patients. DESIGN. A 6-month prospective cohort study was given to...

Production and Characterization of Recombinant Aspergillus fumigatus Cu,Zn Superoxide Dismutase and Its Recognition by Immune Human Sera

Holdom, M. D., Lechenne, B., Hay, R. J., Hamilton, A. J., Monod, M.

The Cu,Zn superoxide dismutase (SOD) of Aspergillus fumigatus has previously been purified and shown to be immunoreactive to the sera of patients with aspergillosis; however, the purification of...

Rapid Detection of Candida albicans in Clinical Samples by DNA Amplification of Common Regions from C. albicans-Secreted Aspartic Proteinase Genes

Flahaut, M., Sanglard, D., Monod, M., Bille, J., Rossier, M.

Laboratory diagnosis based on genomic amplification methods such as PCR may provide an alternative and more sensitive method than conventional culture for the early detection of deep-seated...

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.

Sanglard, D, Kuchler, K, Ischer, F, Pagani, J L, Monod, M, Bille, J

Azole antifungal agents, and especially fluconazole, have been used widely to treat oropharyngeal candidiasis in patients with AIDS. An increasing number of cases of clinical resistance against...

Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.

Sanglard, D, Ischer, F, Monod, M, Bille, J

Some Candida albicans isolates from AIDS patients with oropharyngeal candidiasis are becoming resistant to the azole antifungal agent fluconazole after prolonged treatment with this compound. Most of...

Molecular characterization of the food-borne fungus Neosartorya fischeri (Malloch and Cain).

Girardin, H, Monod, M, Latgé, J P

The food-borne fungus Neosartorya fischeri, which is phenotypically related to the human opportunistic pathogen Aspergillus fumigatus, causes spoilage of heat-processed fruit products. Genomic...

Dipeptidyl-peptidase IV secreted by Aspergillus fumigatus, a fungus pathogenic to humans.

Beauvais, A, Monod, M, Wyniger, J, Debeaupuis, J P, Grouzmann, E, Brakch, N, ...

A dipeptidyl-peptidase IV was purified from the culture medium of the human-pathogenic fungus Aspergillus fumigatus. The enzyme has an apparent molecular mass of 95 kDa and contained approximately 10...

Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.

Hube, B, Sanglard, D, Odds, F C, Hess, D, Monod, M, Schäfer, W, ...

Secreted aspartyl proteinases (Saps), encoded by a gene family with at least nine members (SAP1 to SAP9), are one of the most discussed virulence factors produced by the human pathogen Candida...

A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.

Sanglard, D, Hube, B, Monod, M, Odds, F C, Gow, N A

Secreted aspartyl proteinases (Saps) from Candida albicans are encoded by a multigene family with at least nine members (SAP1 to SAP9) and are considered putative virulence factors important for the...

Cloning and disruption of the antigenic catalase gene of Aspergillus fumigatus.

Calera, J A, Paris, S, Monod, M, Hamilton, A J, Debeaupuis, J P, Diaquin, M, ...

Aspergillus fumigatus possesses two catalases (described as fast and slow on the basis of their electrophoretic mobility). The slow catalase has been recognized as a diagnostic antigen for...

Cloning and analysis of ermG, a new macrolide-lincosamide-streptogramin B resistance element from Bacillus sphaericus.

Monod, M, Mohan, S, Dubnau, D

To analyze the regulation of a newly discovered macrolide-lincosamide-streptogramin B resistance element (ermG) found in a soil isolate of Bacillus sphaericus, we cloned this determinant and obtained...

Sequence and properties of pIM13, a macrolide-lincosamide-streptogramin B resistance plasmid from Bacillus subtilis.

Monod, M, Denoya, C, Dubnau, D

We initiated a study of pIM13, a multicopy, macrolide-lincosamide-streptogramin B (MLS) plasmid first isolated from a strain of Bacillus subtilis and described by Mahler and Halvorson (J. Gen....

Replication properties of pIM13, a naturally occurring plasmid found in Bacillus subtilis, and of its close relative pE5, a plasmid native to Staphylococcus aureus.

Projan, S J, Monod, M, Narayanan, C S, Dubnau, D

A naturally occurring plasmid from Bacillus subtilis, pIM13, codes for constitutively expressed macrolide-lincosamide-streptogramin B (MLS) resistance, is stably maintained at a high copy number, and...

Two different 16S rRNA genes in a mycobacterial strain.

Ninet, B, Monod, M, Emler, S, Pawlowski, J, Metral, C, Rohner, P, ...

Sequencing of the gene coding for 16S rRNA (16S rDNA) is a well-established method used to identify bacteria, particularly mycobacteria. Unique sequences allow identification of a particular genus...

Fluconazole-resistant recurrent oral candidiasis in human immunodeficiency virus-positive patients: persistence of Candida albicans strains with the same genotype.

Millon, L, Manteaux, A, Reboux, G, Drobacheff, C, Monod, M, Barale, T, ...

Thirty human immunodeficiency virus-positive patients carrying Candida albicans in their oropharynx were treated with fluconazole and were monitored for 90 to 570 days. Fluconazole-resistant C....

Isolation and characterization of a secreted metalloprotease of Aspergillus fumigatus.

Monod, M, Paris, S, Sanglard, D, Jaton-Ogay, K, Bille, J, Latgé, J P

A metalloprotease (MEP) secreted by Aspergillus fumigatus was isolated from an alkaline protease-deficient mutant after the fungus was cultivated in the presence of collagen as the sole nitrogen and...

rodletless mutants of Aspergillus fumigatus.

Thau, N, Monod, M, Crestani, B, Rolland, C, Tronchin, G, Latgé, J P, ...

Conidia of Aspergillus fumigatus adhere in vitro to host proteins and cells via the outer cell wall layer. The rodA gene of A. fumigatus was cloned by homology with the rodA gene of Aspergillus...

The yeast acid phosphatase can enter the secretory pathway without its N-terminal signal sequence.

Silve, S, Monod, M, Hinnen, A, Haguenauer-Tsapis, R

The repressible Saccharomyces cerevisiae acid phosphatase (APase) coded by the PHO5 gene is a cell wall glycoprotein that follows the yeast secretory pathway. We used in vitro mutagenesis to...

Identification of the catalytic residues of the first family of beta(1-3)glucanosyltransferases identified in fungi.

Mouyna, I, Monod, M, Fontaine, T, Henrissat, B, Léchenne, B, Latgé, J P

A new family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases (Gelp), recently identified and characterized in the filamentous fungus Aspergillus fumigatus, showed functional...

Candida colonization and subsequent infections in critically ill surgical patients.

Pittet, D, Monod, M, Suter, P M, Frenk, E, Auckenthaler, R

OBJECTIVE. The authors determined the role of Candida colonization in the development of subsequent infection in critically ill patients. DESIGN. A 6-month prospective cohort study was given to...