Growth of superconducting single-crystalline (Lu, Ca)Ba2Cu3O7-d whiskers (2008)
Deguchi, K., Ogawara, S., Okutsu, T., Nagao, M., Watanabe, T., Mizuguchi, Y., ...
Single-crystalline (Lu, Ca)Ba2Cu3O7-d (Lu(Ca)123) whiskers have been successfully grown using the Te-doping method. X-ray diffraction patterns of Lu(Ca)123 whiskers showed sharp (0 0 l) peaks...
Ishii, S., Nagao, M., Watanabe, T., Tsuda, S., Yamaguchi, T., Takano, Y.
We have synthesized a large amount of boron-doped multiwalled carbon nanotubes (MWNTs) by hot-filament chemical vapor deposition. The synthesis was carried out in a flask using a methanol solution of...
Ishizaka, K., Eguchi, R., Tsuda, S., Yokota, T., Chainani, A., Kiss, T., ...
We investigate the temperature (T)-dependent low-energy electronic structure of a boron-doped diamond thin film using ultrahigh resolution laser-excited photoemission spectroscopy. We observe a clear...
Mukuda, H., Tsuchida, T., Harada, A., Kitaoka, Y., Takenouchi, T., Takano, Y., ...
We have investigated the superconductivity discovered in boron (B)-doped diamonds by means of 11B-NMR on heteroepitaxially grown (111) and (100) films. 11B-NMR spectra for all of the films are...
Periodic Oscillations of Josephson-Vortex Flow Resistance in Oxygen-Deficient Y1Ba2Cu3Ox (2006)
Nagao, M., Urayama, S., Kim, S. M., Wang, H. B., Yun, K. S., Takano, Y., ...
We measured the Josephson vortex flow resistance as a function of magnetic field applied parallel to the ab-planes using annealed Y1Ba2Cu3Ox intrinsic Josephson junctions having high anisotropy...
Ishizaka, K., Eguchi, R., Tsuda, S., Yokoya, T., Kiss, T., Shimojima, T., ...
We have investigated the low energy electronic state of a boron-doped diamond thin film by the ultrahigh resolution laser-excited photoemission spectroscopy. We observed a clear shift of the leading...
Urayama, S., Hatano, T., Wang, H. B., Nagao, M., Kim, S. M., Arai, J.
To investigate in-phase structures (rectangular lattice) of Josephson vortex lattice (JVL) in intrinsic Josephson junctions (IJJs) of Bi2Sr2CaCu2O8+d, we fabricated IJJs with various lateral sizes...
Seto, H., Hishida, M., Nobutou, H., Yamada, N. L., Nagao, M., Takeda, T.
A swollen phase, in which the mean repeat distance of lipid bilayers is larger than the other phases, is found between the liquid-crystalline phase and the interdigitated gel phase in DPPC aqueous...
Low-energy electrodynamics of superconducting diamond (2006)
Ortolani, M., Lupi, S., Baldassarre, L., Calvani, P., Schade, U., Takano, Y., ...
Heavily-boron-doped diamond films become superconducting with critical temperatures $T_c$ well above 4 K. Here we first measure the reflectivity of such a film down to 5 cm$^{-1}$, by also using...
Stereocontrolled synthesis and characterization of cis-poly(arylenevinylene)s (2006)
Katayama, H, Nagao, M, Nishimura, T, Matsui, Y, Fukuse, Y, Wakioka, M, ...
Nagao, M, Pitteloud, C, Kamiyama, T, Otomo, T, Itoh, K, Fukunaga, T, ...
Kobayashi, T, Aomatsu, Y, Iwata, H, Kin, T, Kanehiro, H, Hisanga, M, ...
Dynamic and static fluctuations in polymer gels studied by neutron spin-echo (2006)
Kanaya, T, Takahashi, N, Nishida, K, Seto, H, Nagao, M, Takeda, Y
Neutron resonance spin echo and MIEZE spectrometer development project in Japan (2006)
Kawabata, Y, Hino, M, Kitaguchi, M, Hayashida, H, Tasaki, S, Ebisawa, T, ...
Phonon Softening in Superconducting Diamond (2005)
Hoesch, M., Fukuda, T., Takenouchi, T., Sutter, J. P., Tsutsui, S., Baron, A. Q. R., ...
We observe strong softening of optical phonon modes in superconducting (Tc = 4.2 K) boron doped diamond near the Brillouin zone center using inelastic x-ray scattering from a CVD-grown highly...
Ishikawa, J, Gotoh, Y, Nakamura, K, Kojima, T, Tsuji, H, Ikejiri, T, ...
Nagao, M, Pitteloud, C, Kamiyama, T, Otomo, T, Itoh, K, Fukunaga, T, ...
Katayama, H, Nagao, M, Nishimura, T, Matsui, Y, Umeda, K, Akamatsu, K, ...
Kim, S. M., Wang, H. B., Hatano, T., Urayama, S., Kawakami, S., Nagao, M., ...
We have experimentally investigated the fluxon dynamics in a narrow Bi2Sr2CaCu2O8+d stack with junction length L~1.8 um. As an evidence of high-frequency excitation by a collective cavity mode, under...
Macroscopic quantum tunneling in a d-wave high-Tc superconductor (2004)
Inomata, K., Sato, S., Nakajima, K., Tanaka, A., Takano, Y., Wang, H. B., ...
There is a wide recognition that Josephson-junction-like structures intrinsic to the layered cuprate high temperature superconductors offer an attractive stage for exploiting possible applications to...
Superconductivity in CVD Diamond Thin Film Well-Above Liquid Helium Temperature (2004)
Takano, Y., Nagao, M., Kobayashi, K., Umezawa, H., Sakaguchi, I., Tachiki, M., ...
Diamond has always been adored as a jewel. Even more fascinating is its outstanding physical properties; it is the hardest material known in the world with the highest thermal conductivity....
Electron emission properties of Spindt-type platinum field emission cathodes (2004)
Gotoh, Y, Nagao, M, Nozaki, D, Utsumi, K, Inoue, K, Nakatani, T, ...
Kawabata, Y., Nagao, M., Seto, H., Komura, S., Taheda, T., Schwahn, D., ...
This version is available at the following Publisher URL: http://prl.aps.org
Electron emission properties of Spindt-type platinum field emission cathodes (2004)
Gotoh, Y, Nagao, M, Nozaki, D, Utsumi, K, Inoue, K, Nakatani, T, ...
Nakane, T., Mochiku, T., Kito, H., Nagao, M., Itoh, J., Kumakura, H., ...
The metastable phase of an yttrium sesquicarbide compound, which was vary recently reported as a new superconductive phase with a Tc value of 18 K, was prepared under high pressure from the nominal...
Kobayashi, T, Aomatsu, Y, Iwata, H, Kin, T, Kanehiro, H, Hisanaga, M, ...
Fabrication of gated niobium nitride field emitter array (2001)
Gotoh, Y, Kashiwagi, Y, Nagao, M, Kondo, T, Tsuji, H, Ishikawa, J
Spontaneous vortex phase in ErNi2B2C (2001)
Kawano-Furukawa, H., Habuta, E., Nagata, T., Nagao, M., Yoshizawa, H., Furukawa, N., ...
Below T_{WFM} ~ 2.75K, a weak ferromagnetism and superconductivity coexist in ErNi2B2C. In the present paper, a possibility of a spontaneous vortex phase was examined directly by small angle neutron...
Fabrication of gated niobium nitride field emitter array (2001)
Gotoh, Y, Kashiwagi, Y, Nagao, M, Kondo, T, Tsuji, H, Ishikawa, J
Gotoh, Y, Kondo, T, Nagao, M, Tsuji, H, Ishikawa, J, Hayashi, K, ...
Aomatsu, Y, Nakajima, Y, Ohyama, T, Kin, T, Kanehiro, H, Hisanaga, M, ...
Gotoh, Y, Kondo, T, Nagao, M, Tsuji, H, Ishikawa, J, Hayashi, K, ...
An Estimate of Referent of Noun Phrases in Japanese Sentences (1999)
In machine translation and man-machine dialogue, it is important to clarify referents of noun phrases. We present a method for determining the referents of noun phrases in Japanese sentences by using...
Resolution of Verb Ellipsis in Japanese Sentence using Surface Expressions and Examples (1999)
Verbs are sometimes omitted in Japanese sentences. It is necessary to recover omitted verbs for purposes of language understanding, machine translation, and conversational processing. This paper...
Resolution of Indirect Anaphora in Japanese Sentences Using Examples 'X no Y (Y of X)' (1999)
Murata, M., Isahara, H., Nagao, M.
A noun phrase can indirectly refer to an entity that has already been mentioned. For example, ``I went into an old house last night. The roof was leaking badly and ...'' indicates that ``the roof''...
Pronoun Resolution in Japanese Sentences Using Surface Expressions and Examples (1999)
Murata, M., Isahara, H., Nagao, M.
In this paper, we present a method of estimating referents of demonstrative pronouns, personal pronouns, and zero pronouns in Japanese sentences using examples, surface expressions, topics and foci....
Tsuzaki, K., Matsuyama, H., Nagao, M., Maki, T.
Superplasticity and microstructural change during deformation of a 25Cr-7Ni-3Mo alpha/gamma micro duplex stainless steel with fine alpha and gamma grain sizes (appr. 1 microns) showed high strain...
Murata, M, Shiraishi, T, Fukutome, K, Watanabe, M, Nagao, M, Kubota, Y, ...
Okonogi, H, Ushijima, T, Zhang, XB, Heddle, JA, Suzuki, T, Sofuni, T, ...
Genetic alterations of androgen receptor gene in Japanese human prostate cancer (1997)
Watanabe, M, Ushijima, T, Shiraishi, T, Yatani, R, Shimazaki, J, Kotake, T, ...
APC gene mutations in human prostate cancer (1996)
Watanabe, M, Kakiuchi, H, Kato, H, Shiraishi, T, Yatani, R, Sugimura, T, ...
Structure change of δ' precipitates during heating at a constant rate in Al-Li binary alloys (1993)
Okuda, H., Nagao, M., Tanaka, M., Osamura, K., Amemiya, Y.
No abstract available
Structure change of δ' precipitates during heating at a constant rate in Al-Li binary alloys (1993)
Okuda, H., Nagao, M., Tanaka, M., Osamura, K., Amemiya, Y.
No abstract available
Structure change of δ' precipitates during heating at a constant rate in Al-Li binary alloys (1993)
Okuda, H., Nagao, M., Tanaka, M., Osamura, K., Amemiya, Y.
No abstract available
A low loss transformer using a rotating magnetic field (1992)
Nakata, Takayoshi, Takahashi, N., Fujiwara, K., Nakano, Masanori, Nagao, M.
A type of transformer with reduced iron loss, which is excited by a semirotating magnetic field, has been investigated. Factors (method of excitation and slits in the core) affecting iron losses are...
Low loss transformer using rotating magnetic field (1992)
Nakata, Takayoshi, Takahashi, Norio, Fujiwara, Koji, Nakano, Masanori, Nagao, M.
A Taql RFLP in the human ret proto-oncogene (1990)
Tahira, T., Shiraishi, M., Ishizaka, Y., Ikeda, I., Sakai, R., Sugimura, T., ...
An Attempt to Computerized Dictionary Data Bases (1980)
M. Nagao, J. Tsujii, Y. Ueda, M. Takiyama
Two dictionary data base systems developed at Kyoto University are presented in this paper. One is the system for a Japanese dictionary ( Shinmeikai Kokugojiten, published by Sansei-do) and the other...
A Machine Translation System from Japanese into English: Another Perspective of MT Systems (1980)
M. Nagao, J. Tsujii, K. Mitamura, H. Hirakawa, M. Kume
A machine translation system from Japanese into English is described. The system aims at trans-lation of computer manuals, and basically follows to the transfer approach. The design principles of the...
Changes in the amount of growth inhibitors by gibberellin (GA) treatment in tubers of Begonia evaniana was studied. Acidic, neutral and basic ethyl acetate-soluble and n-butanol-soluble growth...
Toyota, M, Canzian, F, Ushijima, T, Hosoya, Y, Kuramoto, T, Serikawa, T, ...
Representational difference analysis (RDA) was applied to isolate chromosomal markers in the rat. Four series of RDA [restriction enzymes, BamHI and HindIII; subtraction of ACI/N (ACI) amplicon from...
Kakiuchi, H, Watanabe, M, Ushijima, T, Toyota, M, Imai, K, Weisburger, J H, ...
The APC gene plays a major role in human colon carcinogenesis. We determined the genomic structure of the rat Apc gene, and we analyzed mutations in colon tumors induced in F344 rats by...
Chun, Y S, Shima, H, Nagasaki, K, Sugimura, T, Nagao, M
Protein phosphatase 1 gamma 2 (PP1 gamma 2) is a testis-specific isotype of the protein-serine/threonine-phosphatase type 1 catalytic subunit. Three native forms of PP1 gamma 2 were detected in a...
Characterization of the PP2A alpha gene mutation in okadaic acid-resistant variants of CHO-K1 cells.
Shima, H, Tohda, H, Aonuma, S, Nakayasu, M, DePaoli-Roach, A A, Sugimura, T, ...
Okadaic acid (OA)-resistant variants of Chinese hamster ovary cells, clones CHO/OAR6-6 and CHO/OAR2-3, were isolated from a CHO-K1 culture. These variant cells were 17- to 26-fold more resistant to...
Makino, H, Ishizaka, Y, Tsujimoto, A, Nakamura, T, Onda, M, Sugimura, T, ...
There are reports of p53 gene mutations in various human cancers but not in rat tumor cell lines or rat primary tumor tissue. We found a p53 gene mutation in a cell line of a spontaneous squamous...
Kaneko, T, Shima, H, Esumi, H, Ochiai, M, Nagase, S, Sugimura, T, ...
Nagase analbuminemic rats (NARs) have a 7-base-pair deletion at the 5' splice site of the HI intron of the albumin gene. The level of immunohistochemically albumin-positive hepatocytes is about 1 per...
Nakayasu, M, Shima, H, Aonuma, S, Nakagama, H, Nagao, M, Sugimura, T
a1-1 cells, a transformant line obtained by transfection of NIH 3T3 cells with human c-Ha-rasT24 (hc-Ha-rasT24), were converted to morphologically normal flat cells following a 2-week culture in the...
Shima, H, Nakayasu, M, Aonuma, S, Sugimura, T, Nagao, M
In HL-60 cells, a human promyelocytic leukemia cell line, the human c-myc gene, designated MYC, is amplified about 16-fold. On differentiation of the HL-60 cells into granulocytes induced by several...
Flat reversion by okadaic acid of raf and ret-II transformants.
Sakai, R, Ikeda, I, Kitani, H, Fujiki, H, Takaku, F, Rapp, U, ...
Okadaic acid is a non-phorbol 12-myristate 13-acetate (PMA)-type tumor promoter on mouse skin and known to be a potent inhibitor of serine/threonine protein phosphatases. Contrary to expectation from...
Activation of human c-raf-1 by replacing the N-terminal region with different sequences.
Tahira, T, Ochiai, M, Hayashi, K, Nagao, M, Sugimura, T
Two transformants of NIH 3T3 cells, obtained by the transfection of human colon cancer and normal colon DNAs, contained activated c-raf-1. In both the activated c-raf-1, the 5' half of the c-raf-1...
Activation of rat c-raf during transfection of hepatocellular carcinoma DNA.
Ishikawa, F, Takaku, F, Hayashi, K, Nagao, M, Sugimura, T
Rat c-raf was found to be activated in a transformant obtained with DNA of a hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline. This activated c-raf was cloned in a cosmid...
Konda, Y, Nishisaki, H, Nakano, O, Matsuda, K, Wada, K, Nagao, M, ...
We studied cellular processes activated by prostaglandins (PG) that are involved in the protection of gastric chief cell injury estimated in terms of dye exclusion test, release of lactate...
A TaqI RFLP in the human ret proto-oncogene
Tahira, T., Shiraishi, M., Ishizaka, Y., Ikeda, I., Sakai, R., Sugimura, T., ...
Interactions of norharman and harman with DNA.
Hayashi, K, Nagao, M, Sugimura, T
The interactions of norharman (9H-pyrido [3,4-b] indole) and harman (1-methyl-9H-pyrido [3,4-b] indole) with DNA were studied. DNA caused remarkable fluorescence quenching and change in the...
Rat c-raf oncogene activation by a rearrangement that produces a fused protein.
Ishikawa, F, Takaku, F, Nagao, M, Sugimura, T
In a previous study, activated rat c-raf was detected by an NIH 3T3 cell transfection assay, and a rearrangement was demonstrated in the 5' half of the sequence of the gene. In the present study, the...
Effects of O2 and some respiratory inhibitors on the induction and release of bud dormancy were examined with the aerial tubers of different ages of Begonia evansiana Andr. Oxygen was needed not only...
Structure of the c-Ki-ras gene in a rat fibrosarcoma induced by 1,8-dinitropyrene.
Tahira, T, Hayashi, K, Ochiai, M, Tsuchida, N, Nagao, M, Sugimura, T
Restriction enzyme maps were made of the region around exons 1 and 2 of activated c-Ki-ras of a fibrosarcoma (1,8-DNP2) induced in a rat by 1,8-dinitropyrene. Nucleotide sequence analysis revealed...
Wakabayashi, K, Ochiai, M, Saitô, H, Tsuda, M, Suwa, Y, Nagao, M, ...
After treatment with nitrite, Japanese soy sauce was strongly mutagenic to Salmonella typhimurium TA100 without S9 mixture. Two precursors of the mutagen were isolated from Japanese soy sauce, and...
Nagao, M, Wakabayashi, K, Ushijima, T, Toyota, M, Totsuka, Y, Sugimura, T
Heterocyclic amines (HCAs) are mutagens/carcinogens to which humans are exposed on almost a daily basis. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhlP) is the most abundant of the various...
Carcinogenicity of food mutagens.
Sugimura, T, Nagao, M, Wakabayashi, K
Cancer cells are produced by the accumulation of genetic alterations in somatic cells. Those genetic alterations are produced by xenobiotics, which enter the human body from the environment, and by...
Mutagenic activities of heterocyclic amines in Chinese hamster lung cells in culture.
Terada, M, Nagao, M, Nakayasu, M, Sakamoto, H, Nakasato, F, Sugimura, T
A mutation assay system with Chinese hamster lung cells (CHL) using diphtheria toxin resistance as a selective marker has been established. The mutagenic activities of heterocyclic amines, originally...
Mutagens in coffee and other beverages.
Nagao, M, Fujita, Y, Wakabayashi, K, Nukaya, H, Kosuge, T, Sugimura, T
A cup of coffee contains mutagens which produce about 5 X 10(4)-10(5) revertants of Salmonella typhimurium TA 100 without S9 mix. One of the mutagens was identified to be methylglyoxal. Methylglyoxal...
Exposure to heterocyclic amines.
Wakabayashi, K, Ushiyama, H, Takahashi, M, Nukaya, H, Kim, S B, Hirose, M, ...
Many mutagenic heterocyclic amines (HAs) have been isolated from cooked foods and pyrolysates of amino acids and proteins, and the carcinogenicity of 10 of these HAs in rodents and of 1 in monkeys...
Loss of amplified genes by poly(ADP-ribose) polymerase inhibitors.
Nagao, M, Nakayasu, M, Aonuma, S, Shima, H, Sugimura, T
A poly(ADP-ribose) polymerase inhibitor, benzamide (BA), was found to induce flat revertants of NIH 3T3 cells that had been transformed by human Ha-ras, rat Ki-ras, rat c-raf, and human ret-II. These...
Toyota, M, Canzian, F, Ushijima, T, Hosoya, Y, Kuramoto, T, Serikawa, T, ...
Representational difference analysis (RDA) was applied to isolate chromosomal markers in the rat. Four series of RDA [restriction enzymes, BamHI and HindIII; subtraction of ACI/N (ACI) amplicon from...
Kakiuchi, H, Watanabe, M, Ushijima, T, Toyota, M, Imai, K, Weisburger, J H, ...
The APC gene plays a major role in human colon carcinogenesis. We determined the genomic structure of the rat Apc gene, and we analyzed mutations in colon tumors induced in F344 rats by...
Chun, Y S, Shima, H, Nagasaki, K, Sugimura, T, Nagao, M
Protein phosphatase 1 gamma 2 (PP1 gamma 2) is a testis-specific isotype of the protein-serine/threonine-phosphatase type 1 catalytic subunit. Three native forms of PP1 gamma 2 were detected in a...
Characterization of the PP2A alpha gene mutation in okadaic acid-resistant variants of CHO-K1 cells.
Shima, H, Tohda, H, Aonuma, S, Nakayasu, M, DePaoli-Roach, A A, Sugimura, T, ...
Okadaic acid (OA)-resistant variants of Chinese hamster ovary cells, clones CHO/OAR6-6 and CHO/OAR2-3, were isolated from a CHO-K1 culture. These variant cells were 17- to 26-fold more resistant to...
Makino, H, Ishizaka, Y, Tsujimoto, A, Nakamura, T, Onda, M, Sugimura, T, ...
There are reports of p53 gene mutations in various human cancers but not in rat tumor cell lines or rat primary tumor tissue. We found a p53 gene mutation in a cell line of a spontaneous squamous...
Kaneko, T, Shima, H, Esumi, H, Ochiai, M, Nagase, S, Sugimura, T, ...
Nagase analbuminemic rats (NARs) have a 7-base-pair deletion at the 5' splice site of the HI intron of the albumin gene. The level of immunohistochemically albumin-positive hepatocytes is about 1 per...
Nakayasu, M, Shima, H, Aonuma, S, Nakagama, H, Nagao, M, Sugimura, T
a1-1 cells, a transformant line obtained by transfection of NIH 3T3 cells with human c-Ha-rasT24 (hc-Ha-rasT24), were converted to morphologically normal flat cells following a 2-week culture in the...
Shima, H, Nakayasu, M, Aonuma, S, Sugimura, T, Nagao, M
In HL-60 cells, a human promyelocytic leukemia cell line, the human c-myc gene, designated MYC, is amplified about 16-fold. On differentiation of the HL-60 cells into granulocytes induced by several...
Flat reversion by okadaic acid of raf and ret-II transformants.
Sakai, R, Ikeda, I, Kitani, H, Fujiki, H, Takaku, F, Rapp, U, ...
Okadaic acid is a non-phorbol 12-myristate 13-acetate (PMA)-type tumor promoter on mouse skin and known to be a potent inhibitor of serine/threonine protein phosphatases. Contrary to expectation from...
Activation of human c-raf-1 by replacing the N-terminal region with different sequences.
Tahira, T, Ochiai, M, Hayashi, K, Nagao, M, Sugimura, T
Two transformants of NIH 3T3 cells, obtained by the transfection of human colon cancer and normal colon DNAs, contained activated c-raf-1. In both the activated c-raf-1, the 5' half of the c-raf-1...
Activation of rat c-raf during transfection of hepatocellular carcinoma DNA.
Ishikawa, F, Takaku, F, Hayashi, K, Nagao, M, Sugimura, T
Rat c-raf was found to be activated in a transformant obtained with DNA of a hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline. This activated c-raf was cloned in a cosmid...
Konda, Y, Nishisaki, H, Nakano, O, Matsuda, K, Wada, K, Nagao, M, ...
We studied cellular processes activated by prostaglandins (PG) that are involved in the protection of gastric chief cell injury estimated in terms of dye exclusion test, release of lactate...
A TaqI RFLP in the human ret proto-oncogene
Tahira, T., Shiraishi, M., Ishizaka, Y., Ikeda, I., Sakai, R., Sugimura, T., ...
Interactions of norharman and harman with DNA.
Hayashi, K, Nagao, M, Sugimura, T
The interactions of norharman (9H-pyrido [3,4-b] indole) and harman (1-methyl-9H-pyrido [3,4-b] indole) with DNA were studied. DNA caused remarkable fluorescence quenching and change in the...
Rat c-raf oncogene activation by a rearrangement that produces a fused protein.
Ishikawa, F, Takaku, F, Nagao, M, Sugimura, T
In a previous study, activated rat c-raf was detected by an NIH 3T3 cell transfection assay, and a rearrangement was demonstrated in the 5' half of the sequence of the gene. In the present study, the...
Effects of O2 and some respiratory inhibitors on the induction and release of bud dormancy were examined with the aerial tubers of different ages of Begonia evansiana Andr. Oxygen was needed not only...
Structure of the c-Ki-ras gene in a rat fibrosarcoma induced by 1,8-dinitropyrene.
Tahira, T, Hayashi, K, Ochiai, M, Tsuchida, N, Nagao, M, Sugimura, T
Restriction enzyme maps were made of the region around exons 1 and 2 of activated c-Ki-ras of a fibrosarcoma (1,8-DNP2) induced in a rat by 1,8-dinitropyrene. Nucleotide sequence analysis revealed...
Wakabayashi, K, Ochiai, M, Saitô, H, Tsuda, M, Suwa, Y, Nagao, M, ...
After treatment with nitrite, Japanese soy sauce was strongly mutagenic to Salmonella typhimurium TA100 without S9 mixture. Two precursors of the mutagen were isolated from Japanese soy sauce, and...
Nagao, M, Wakabayashi, K, Ushijima, T, Toyota, M, Totsuka, Y, Sugimura, T
Heterocyclic amines (HCAs) are mutagens/carcinogens to which humans are exposed on almost a daily basis. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhlP) is the most abundant of the various...
Carcinogenicity of food mutagens.
Sugimura, T, Nagao, M, Wakabayashi, K
Cancer cells are produced by the accumulation of genetic alterations in somatic cells. Those genetic alterations are produced by xenobiotics, which enter the human body from the environment, and by...
Mutagenic activities of heterocyclic amines in Chinese hamster lung cells in culture.
Terada, M, Nagao, M, Nakayasu, M, Sakamoto, H, Nakasato, F, Sugimura, T
A mutation assay system with Chinese hamster lung cells (CHL) using diphtheria toxin resistance as a selective marker has been established. The mutagenic activities of heterocyclic amines, originally...
Mutagens in coffee and other beverages.
Nagao, M, Fujita, Y, Wakabayashi, K, Nukaya, H, Kosuge, T, Sugimura, T
A cup of coffee contains mutagens which produce about 5 X 10(4)-10(5) revertants of Salmonella typhimurium TA 100 without S9 mix. One of the mutagens was identified to be methylglyoxal. Methylglyoxal...
Exposure to heterocyclic amines.
Wakabayashi, K, Ushiyama, H, Takahashi, M, Nukaya, H, Kim, S B, Hirose, M, ...
Many mutagenic heterocyclic amines (HAs) have been isolated from cooked foods and pyrolysates of amino acids and proteins, and the carcinogenicity of 10 of these HAs in rodents and of 1 in monkeys...
Loss of amplified genes by poly(ADP-ribose) polymerase inhibitors.
Nagao, M, Nakayasu, M, Aonuma, S, Shima, H, Sugimura, T
A poly(ADP-ribose) polymerase inhibitor, benzamide (BA), was found to induce flat revertants of NIH 3T3 cells that had been transformed by human Ha-ras, rat Ki-ras, rat c-raf, and human ret-II. These...
Isolated persistent hypermethioninemia.
Mudd, S H, Levy, H L, Tangerman, A, Boujet, C, Buist, N, Davidson-Mundt, A, ...
New information has been obtained on 30 patients with isolated persistent hypermethioninemia, most of them previously unreported. Biopsies to confirm the presumptive diagnosis of partially deficient...
Unexpected atrial fibrillation during tooth extraction in a sedated elderly patient.
Umino, M., Ohwatari, T., Shimoyama, K., Nagao, M.
A case is reported of unexpected atrial fibrillation in response to tooth extraction under intravenous sedation in a 70-yr-old patient with thoracic aneurysm of the aorta. Atrial fibrillation...
Oral-facial-digital syndrome type IX in a patient with Dandy-Walker malformation.
Nagai, K, Nagao, M, Nagao, M, Yanai, S, Minagawa, K, Takahashi, Y, ...
We report a girl with oral, facial, and digital anomalies including multiple alveolar frenula, lobulated tongue with nodules, a posterior cleft palate, hypertelorism, a prominent forehead with a...
A new gas dilution method for measuring body volume.
Nagao, N, Tamaki, K, Kuchiki, T, Nagao, M
This study was designed to examine the validity of a new gas dilution method (GD) for measuring human body volume and to compare its accuracy with the results obtained by the underwater weighing...