Ahlen, S., Afshordi, N., Battat, J. B. R., Billard, J., Bozorgnia, N., Burgos, S., ...
We present the case for a dark matter detector with directional sensitivity. This document was developed at the 2009 CYGNUS workshop on directional dark matter detection, and contains contributions...
Epitaxial-strain effect on charge/orbital order in Pr0.5Ca0.5MnO3 films (2009)
Okuyama, D., Nakamura, M., Wakabayashi, Y., Itoh, H., Kumai, R., Yamada, H., ...
Effect of growth orientation on charge- and orbital-ordering (CO-OO) phenomena has been studied for Pr0.5Ca0.5MnO3 epitaxial thin films fabricated on (LaAlO3)0.3-(SrAl0.5Ta0.5O3)0.7 (LSAT) substrates...
Expression of Interest for Neutrinos Scattering on Glass: NuSOnG (2009)
Adams, NuSOnG Collaboration: T., Buge, L., Conrad, J. M., Fisher, P. H., Formaggio, J. A., De Gouvêa, A., ...
We propose a 3500 ton (3000 ton fiducial volume) SiO_2 neutrino detector with sampling calorimetry, charged particle tracking, and muon spectrometers to run in a Tevatron Fixed Target Program....
Adams, T., Batra, P., Bugel, L., Camilleri, L., Conrad, J. M., De Gouvêa, A., ...
We extend the physics case for a new high-energy, ultra-high statistics neutrino scattering experiment, NuSOnG (Neutrino Scattering On Glass) to address a variety of issues including precision QCD...
Long Fat Pipe Congestion Control for Multi-Stream Data Transfer (2009)
M. Nakamura, H. Kamezawa, J. Tamatsukuri, M. Inaba, K. Hiraki, K. Mizuguchi, ...
This manuscript was written for ISPAN03. In this paper, we point out a problem of congestion control mechanism of TCP on Long Fat pipe Network (LFN) by precise analysis using our hand-made tools, and...
Abdelwahab, A., Gardner, M., Parkash, R., Basta, M., Sapp, J., Veltmann, C., ...
Introduction: Scar-related ventricular tachycardia (VT) is often unmappable. Data regarding the outcomes of ablation for mappable vs unmappable VT are lacking. Methods: Catheter ablation of...
Fukuda, S., Ikeda, M., Nakamura, M., Yan, X., Xie, Y.
The efficacy of oral administration of the chelating agent catechol-3,6-bis(methyleiminodiacetic acid) (CBMIDA) for removing uranium from rats after intraperitoneal (i.p.) and intramuscular (i.m.)...
Takeno, S, Nakamura, M, Fukai, R, Ohnishi, J, Ikeda, M
The original publication is available at www.springerlink.com.
Rabi Oscillations in Landau Quantized Graphene (2008)
Dóra, B., Ziegler, K., Thalmeier, T., Nakamura, M.
The canonical model of quantum optics, the Jaynes-Cummings Hamiltonian describes a two level atom in a cavity interacting with electromagnetic field. Graphene, a condensed matter system, possesses...
Precision measurement of neutrino oscillation parameters with KamLAND (2008)
Abe, S., Ebihara, T., Enomoto, S., Furuno, K., Gando, Y., Ichimura, K., ...
The KamLAND experiment has determined a precise value for the neutrino oscillation parameter Δm2 21 and stringent constraints on θ12. The exposure to nuclear reactor antineutrinos is increased...
Effects of sample size on the performance of species distribution models (2008)
Wisz, M.S., Hijmans, R.J., Li, J., Peterson, A.T., Graham, C.H., Guisan, A., ...
A wide range of modelling algorithms is used by ecologists, conservation practitioners, and others to predict species ranges from point locality data. Unfortunately, the amount of data available is...
T. Matsumura, M. Nakamura, J. Okech, K. Onaga
In this paper, we propose and evaluate a distributed and parallel processing method of genetic algorithms on the loosely-coupled multiprocessor systems. In the experimental evaluation, we observe...
Iwata, M., Inoue, S., Kawaguchi, M., Nakamura, M., Konishi, N., Furuya, H.
Background It has been reported that delta-opioid (DOP) receptor agonists may be neuroprotective in the central nervous system. However, the DOP agonist [d-Ala2, d-Leu5]enkephalin (DADLE) does not...
Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis (2007)
Misu, T., Fujihara, K., Kakita, A., Konno, H., Nakamura, M., Watanabe, S., ...
Neuromyelitis optica (NMO) is an inflammatory and necrotizing disease clinically characterized by selective involvement of the optic nerves and spinal cord. There has been a long controversy as to...
Steeves, J. D., Lammertse, D., Curt, A., Fawcett, J. W., Tuszynski, M. H., Ditunno, J. F., ...
An international panel reviewed the methodology for clinical trials of spinal cord injury (SCI), and provided recommendations for the valid conduct of future trials. This is the second of four...
Negative electroretinograms in pericentral pigmentary retinal degeneration (2006)
Kondo, M, Nakamura, M, Terasaki, H, Miyake, Y, ...
The clinical presentation and electrophysiological findings are described of three consecutive cases with pericentral pigmentary retinal degeneration. The responses to bright flashes after dark...
Kanematsu, M, Shimizu, Y, Sato, K, Kim, S, Suzuki, T, Park, B, ...
Okuda, S, Takanaka, M, Nakamura, M, Kato, R, Takahashi, T, Nam, SK, ...
Coronary risk prediction for those with and without diabetes (2006)
Jamrozik, K., Dobson, A., Lam, T. H., Ueshima, H., Patel, A., Gu, D. F., ...
Background Coronary risk prediction 'engines' are now in common use, and their worth is well proven. There remains the question of how to deal with a prior diagnosis of diabetes. Design An individual...
Huxley, R, Barzi, F, Lam, TH, Lawes, CMM, Wong, JW, Woodward, M, ...
Purpose Differences in cardiovascular risk factor levels have been suggested to contribute to the age-related excess risk of coronary heart disease (CHD). The aim of this study was to reliably...
Nakamura, M., Tanaka, Y., Satoh, T., Kawai, M., Hirakata, M., Kaburaki, J., ...
Objectives. To examine the prevalence, clinical associations and pathogenic roles of autoantibodies to CD40 ligand (CD40L) in patients with systemic lupus erythematosus (SLE). Methods. Plasma...
The map-based sequence of the rice genome (2005)
MATSUMOTO, T, WU, JZ, KANAMORI, H, KATAYOSE, Y, FUJISAWA, M, NAMIKI, N, ...
Antisense Transcription in the Mammalian Transcriptome (2005)
Katayama, S., Tomaru, Y., Kasukawa, T., Waki, K., Nakanishi, M., Nakamura, M., ...
Antisense transcription (transcription from the opposite strand to a protein-coding or sense strand) has been ascribed roles in gene regulation involving degradation of the corresponding sense...
Migita, K., Miyashita, T., Maeda, Y., Nakamura, M., Yatsuhashi, H., Ishibashi, H., ...
Objective. Cytokine-induced hepatic serum amyloid A (SAA) synthesis is the critical step in the pathogenesis of AA amyloidosis secondary to rheumatoid arthritis (RA). This study was conducted to...
Migita, K., Miyashita, T., Maeda, Y., Nakamura, M., Yatsuhashi, H., Ishibashi, H., ...
Objective. Cytokine-induced hepatic serum amyloid A (SAA) synthesis is the critical step in the pathogenesis of AA amyloidosis secondary to rheumatoid arthritis (RA). This study was conducted to...
Nakamura, M., Tanaka, Y., Satoh, T., Kawai, M., Hirakata, M., Kaburaki, J., ...
Objectives. To examine the prevalence, clinical associations and pathogenic roles of autoantibodies to CD40 ligand (CD40L) in patients with systemic lupus erythematosus (SLE). Methods. Plasma...
Effectiveness of naked-eye vision feedback for training human teleoperators (2004)
Munasinghe, S.R., Usui, T., Nakamura, M., Egashira, N., Lee, Ju-Jang
Effective training is essential for human teleoperators to deliver satisfactory performance in actual tasks. Teleoperation is naturally a very difficult task due to the absence of naked-eye vision...
Investigation of mechanical behavior of copper in Nb3Sn superconducting composite wire (2004)
Hojo, M, Matsuoka, T, Nakamura, M, Tanaka, M, Adachi, T, Ochiai, S, ...
Ochiai, S, Miyazaki, N, Doko, D, Nagai, T, Nakamura, M, Okuda, H, ...
Mhurchu, CN, Rodgers, A, Pan, WH, Gu, DF, Parag, V, Lin, R, ...
Background Few prospective data from the Asia-Pacific region are available relating body mass index (BMI) to the risks of stroke and ischaemic heart disease (IHD). Our objective was to assess the...
Blood glucose and risk of cardiovascular disease in the Asia Pacific region (2004)
Lawes, CMM, Parag, V, Bennett, DA, Suh, I, Whitlock, G, Barzi, F, ...
OBJECTIVE - To assess the shape and strength of the association between usual blood glucose and cardiovascular disease (CVD) in Asian and Australasian cohorts and to determine the impact of adjusting...
Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Melzer, O, Oldeman, R G C, ...
A study of quasi-elastic production of charmed baryons in charged-current interactions of neutrinos with the nuclear emulsion target of CHORUS is presented. In a sample of about 46000 interactions...
Measurement of the $Z/A$ dependence of neutrino charged-current total cross-sections (2003)
Kayis-Topaksu, A, Onengüt,G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, ...
A relative measurement of total cross-sections is reported for polyethylene, marble, iron, and lead targets for the inclusive charged-current reaction nu_mu + N -> mu^- + X. The targets, passive...
Effects of outflow from the surface of a sphere on drag, shear lift, and scalar diffusion (2003)
Kurose, R, Makino, H, Komori, S, Nakamura, M, Akamatsu, F, Katsuki, M
Measurement of $\Lambda^{+}_{c}$ production in neutrino charged-current interactions (2003)
Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Melzer, O, Oldeman, R G C, ...
A measurement of $\Lambda_c^+$ production in neutrino nucleon charged-current interactions is presented. In a sub-sample of about 50 000 interactions located in the emulsion target of the CHORUS...
Hojo, M, Nakamura, M, Matsuoka, T, Tanaka, M, Ochiai, S, Sugano, M, ...
Effects of outflow from the surface of a sphere on drag, shear lift, and scalar diffusion (2003)
Kurose, R, Makino, H, Komori, S, Nakamura, M, Akamatsu, F, Katsuki, M
Matsuzaki, Y., Matsukawa, T., Ohki, K., Yamamoto, Y., Nakamura, M., Oshibuchi, T.
Background. Even mild perioperative hypothermia is associated with several severe adverse effects. Resistive heating has possible advantages compared with other active warming systems because it can...
Kayis-Topaksu, A, Onengüt, G, De Jong, M, Melzer, O, Oldeman, R G C, Pesen, E, ...
During the years 1994--1997, the emulsion target of the CHORUS detector was exposed to the CERN-SPS Wide Band Neutrino Beam. The improvements of the past few years in the automatic emulsion scanning...
Photonic crystal light deflection devices using the superprism effect (2002)
Baba, Toshihiko, Nakamura, M., 馬場, 俊彦, ババ, トシヒコ
The superprism effect allows wide-angle deflection of the light beam in a photonic crystal (PC) by a slight change of the wavelength or the incident angle. In this paper, we discuss such light...
Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, ...
We report on a search for associated charm production in neutrino charged-current interactions in the CHORUS experiment, based on the visual observation of charmed-particle decays. The search differs...
Measurement of $D^0$ production in neutrino charged-current interactions (2002)
Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Melzer, O, Oldeman, R G C, ...
During the years 1994--1997, the emulsion target of the CHORUS detector was exposed to the Wide Band Neutrino Beam from the CERN-SPS. About 170,000 neutrino interactions were successfully located in...
A Hybrid Search based on Genetic Algorithms and Tabu Search for Vehicle (2002)
B. M. Ombuki, M. Nakamura, M. Osamu, Beatrice M. Ombuki
We present a hybrid search technique based on metaheuristics for approximately solving the vehicle routing problem with time windows (VRPTW). The approach is two phased; a global customer clustering...
Observation of weak neutral current neutrino production of $J/\psi$ (2001)
Eskut, E, Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, ...
Observation of \jpsi production by neutrinos in the calorimeter of the CHORUS detector exposed to the CERN SPS wide-band \numu beam is reported. A spectrum-averaged cross-section...
Evaluation of electron bunch shapes using the spectra of the coherent radiation (2001)
Nakamura, M, Takanaka, M, Okuda, S, Kozawa, T, Kato, R, Takahashi, T, ...
Large-scale slope failure and active erosion occurring in the southwest Ryukyu fore-arc area (2001)
Matsumoto, T., Kimura, M., Nakamura, M., Ono, T.
The southwestern Ryukyu area east of Taiwan Island is an arcuate boundary between Philippine Sea Plate and Eurasian Plate. The topographic features in the area are characterised by (1) a large-scale...
Observations of convection in the dayside magnetosphere by the beam instrument on Geotail (2001)
Matsui, H., Nakamura, M., Mukai, T., Tsuruda, K., Hayakawa, H.
We report observations of magnetospheric convection by the beam instrument, EFD-B, on Geotail. The region analyzed in this study is mainly the afternoon sector of the magnetosphere between L = 9.7 -...
Interleukin-1-induced subacromial synovitis and shoulder pain in rotator cuff diseases (2001)
Gotoh, M., Hamada, K., Yamakawa, H., Yanagisawa, K., Nakamura, M., Yamazaki, H., ...
Objective. To determine the relationship between the expression of interleukin‐1β (IL‐1β) and IL‐1 receptor antagonists (IL‐1ra) in the subacromial...
Eskut, E, Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, ...
A first analysis of the complete set of data collected by CHORUS in the years 1994-1997 is presented. The search for $\nut$ charged current events has been performed for both leptonic and hadronic...
Matsui, H, Nakamura, M, Terasawa, T, Izaki, Y, Mukai, T, Tsuruda, K, ...
Mineshige, A, Izutsu, J, Nakamura, M, Nigaki, K, Kobune, M, Fujii, S, ...
Nakamura, M, Furukawa, Y, Sasaki, R, Masuyama, J, Kikuchi, J, Iwase, S, ...
Annis, P, Aoki, S, Artamonov, S A, Barbuto, E, Di Bartolomeo, A, Bonekämper, D, ...
We report on the first direct observation of a neutrino induced charged-current interaction with two subsequent decays of short-lived particles close to the interaction vertex. This rare double- kink...
Eskut, E, Kayis, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, ...
Part of the neutrino events collected in 1994-1995 by the CHORUS experiment has been analysed. A search was performed for $\nu_{\tau}$ charged current interactions followed by the $\tau$ lepton deca...
A Search for $\nu_\mu \to \nu_\tau$ Oscillation (1998)
Eskut, E, Kayis, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, ...
CHORUS is an experiment searching for $\numtonut$ oscillation in the CERN wide band neutrino beam with a {\sl hybrid} setup consisting of a nuclear emulsion target followed by electronic detectors....
Vision-Based Robot Learning Towards RoboCup: Osaka University "Trackies" (1998)
S. Suzuki, Y. Takahashi, E. Uchibe, M. Nakamura, C. Mishima, H. Ishizuka, ...
. The authors have applied reinforcement learning methods to real robot tasks in several aspects. We selected a skill of soccer as a task for a vision-based mobile robot. In this paper, we explain...
Yamazaki, H, Kijima, H, Ohnishi, Y, Abe, Y, Oshika, Y, Tsuchida, T, ...
Makkar, R.R., Eigler, N.L., Kaul, S., Frimerman, A., Nakamura, M., Shah, P.K., ...
Aims Use of ticlopidine in coronary stenting is limited by delayed onset of action. We studied the effects of clopidogrel, a rapidly acting analog of ticlopidine alone, and in combination with...
The CHORUS scintillating fiber tracker and its monitoring systems (1997)
Annis, P, Aoki, S, Brooijmans, G, Brunner, J, Dupraz, J P, Dupont, J, ...
A scintillating fiber tracker system consisting of more than one million fibers has been successfully constructed and made operational for the CERN WA95/CHORUS experiment. The design and construction...
The CHORUS experiment to search for $\nu_{\mu} \rightarrow \nu_{\tau}$ oscillation (1997)
Eskut, E, Kayis, A, Onengüt, G, Van Dantzig, R, Konijn, J, Oldeman, R G C, ...
A new experimental apparatus, designed principally for a high sensitivity search for $\nu_{\mu}~\rightarrow~\nu_{\tau}$ oscillation, has been successfully constructed and made operational by the...
The CHORUS neutrino oscillation search experiment (1997)
Eskut, E, Kayis, A, Onengüt, G, Van Dantzig, R, Konijn, J, Oldeman, R G C, ...
The CHORUS experiment has successfully finished run I (320~000 recorded \numu\ CC in 94/95) and performed half of run II (225~000 \numu\ CC in 96). The analysis chain was exercised on a small data...
Vision-Based Learning for Real Robot: Towards RoboCup (1997)
Suzuki Takahashi, S. Suzuki, Y. Takahashi, E. Uchibe, M. Nakamura, C. Mishima, ...
The authors have applied reinforcement learning method to a mobile robot with vision system. We selected a task for the robot from skills for playing soccer. In the rst stage, a robot learned to...
Effects of Chromosome Migration on a Parallel and Distributed Genetic Algorithm (1997)
T. Matsumura, M. Nakamura, D. Miyazato, K. Onaga, J. Okech
In this paper we propose a parallel and distributed genetic algorithms (PDGA) on fixed network topology multiprocessor systems in which each processor element carries out genetic operations on its...
Induction of IL-1 beta-converting enzyme-independent apoptosis by IL-2 in human T cell lines (1997)
Oda, K, Asao, H, Higuchi, M, Tanaka, N, Moffatt, S, Nakamura, M, ...
Retroperitoneal schwannoma mimicking hepatic tumor in the caudate lobe (1997)
Nakamura, M, Takayama, T, Takayasu, K, Shimada, K, Yamamoto, J, Kosuge, T, ...
Chiba, M., Nakamura, M., Kanaya, Y., Kobayashi, N., Ueshima, K., Kawazoe, K., ...
Aims Reduced skeletal muscle blood flow during exercise is an important factor contributing to exercise intolerance in patients with chronic heart failure. Reactive hyperaemic blood flow is the...
Nakamura, M., Yoshida, H., Arakawa, N., Mizunuma, Y., Makita, S., Hiramori, K.
This study examined possible selective impairment of endothelial dysfunction in the peripheral vascular bed in patients with chronic heart failure in the absence of confounding factors influencing...
A Surface Emitting Laser Amplifier for Parallel Optical Buses (1994)
Ohashi Hamasaki, M. Ohashi, H. Hamasaki, K. Kaminishi, M. Nakamura
h as gain properties, carrier injection, resonant effects, and so on, in order to decide which structure is more effective. Therefore we propose a prototype of a vertical transmission optical...
Scintillating fiber trackers with optoelectronic readout for the Chorus neutrino experiment (1993)
Aoki, S, Dupont, J, Dupraz, J P, Fabre, Jean-Paul, Flegel, Wilfried, Frekers, D, ...
The observation of the muonic decay D$^{\pm}_{s}$ --> $\mu^{\pm}\nu_{\mu}$ (1993)
Aoki, S, Baroni, Giustina, Bisi, V, Breslin, A C, Catanesi, M G, Chiba, K, ...
Erysipelothrix tonsillarum isolated from dogs with endocarditis in Belgium. (1993)
TAKAHASHI, T, TAMURA, Y, YOSHIMURA, H, NAGAMINE, N, KIJIMA, M, NAKAMURA, M, ...
Nakamura, M., Katabuchi, H., Tohya, T., Fukumatsu, Y., Matsuura, K., Okamura, H.
The pathogenesis of pelvic endometriosis has been studied by using scanning electron and light microscopy, observing the surface structure of bluish lesions obtained from 26 patients during...
The first observation of the muonic decay D$^{\pm}_{s}$ --> $\mu^{\pm}\nu_{\mu}$ (1992)
Aoki, S, Baroni, Giustina, Bisi, V, Breslin, A C, Catanesi, M G, Chiba, K, ...
Charm production by 350 GeV/c $\pi^{-}$ interactions in nuclear emulsion (1992)
Aoki, S, Arnold, R, Baroni, Giustina, Bisi, V, Breslin, A C, Catanesi, M G, ...
Narikawa, S., Suzuki, T., Yamamoto, M., Nakamura, M.
Enzymes acting on pyruvate as a parameter of the ATP regeneration system were studied as a cause of metronidazole resistance in Bacteroides fragilis NCTC 11295. The resistant strain had higher...
A search for multiplicity fluctuations in high energy nucleus-nucleus collisions (1990)
Åkesson, T, Almehed, S, Angelis, Aris L S, Aoki, S, Armenise, N, Atherton, Henry W, ...
Direct observation of the decay of beauty particles into charm particles (1990)
Albanese, J P, Alpe, V, Aoki, S, Arnold, R, Baroni, Giustina, Barth, Monique, ...
A hybrid experiment to search for beauty particles (1990)
Aoki, S, Arnold, R, Baroni, Giustina, Barth, Monique, Bartley, J H, Bertrand, D, ...
The production of charmed particles in high-energy $^{16}$O-emulsion central interactions (1990)
Aoki, S, Breslin, A C, Davis, D H, Hoshino, K, Ihara, R, Imada, M, ...
Some properties of charmed particles produced in pi-.nucleus interactions (1990)
Aoki, S, Arnold, R, Baroni, Giustina, Barth, Monique, Bertrand-Coremans, G H, Bisi, V, ...
An attempt to observe directly beauty particles in nuclear emulsions (1990)
Albanese, J P, Allasia, D, Armenise, N, Arnold, R, Baroni, Giustina, Barth, Monique, ...
Provocation of variant angina by alcohol ingestion (1984)
MATSUGUCHI, T., ARAKI, H., ANAN, T., HAYATA, N., NAKAGAKI, O., TAKESHITA, A., ...
The effect of alcohol on variant angina was studied in six patients who had a history of chest pain occurring with alcohol ingestion. On alcohol testing, Holter ECG monitoring was performed and a...
Effect of coronary occlusion on arterial baroreflex control of heart rate (1980)
TAKESHITA, A, MATSUGUCHI, H, NAKAMURA, M
To determine whether the baroreflex control of heart rate is altered during acute myocardial ischaemia, the baroreflex slope was measured at the control state, during coronary occlusion, and at the...
Akiyoshi, T, Nakamura, M, Koga, K, Nakashima, H, Yao, T, Tsuneyoshi, M, ...
Kamio, M, Meguro, A, Ota, M, Nomura, N, Kashiwagi, K, Mabuchi, F, ...
A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis
Ogata, H, Matsui, T, Nakamura, M, Iida, M, Takazoe, M, Suzuki, Y, ...
Clinical and MRI features of Japanese patients with multiple sclerosis positive for NMO‐IgG
Nakashima, I, Fujihara, K, Miyazawa, I, Misu, T, Narikawa, K, Nakamura, M, ...
This study investigates the relation between the serological status of NMO (neuromyelitis optica)‐IgG and the clinical and MRI features in Japanese patients with multiple sclerosis. Serum NMO‐IgG...
Fujiwara, Y., Nakamura, M., Yokoo, S.
Interstrand cross-linking, repair and lethal effects of (-)-(R)-2-aminomethylpyrrolidine(1,1-cyclobutanedicarboxylato++ +) platinum(II) (DWA2114R) were studied in normal human. Fanconi's anaemia (FA)...
Katoh, Y., Nakamura, M., Ohnishi, Y., Shimamura, K., Ueyama, Y., Tamaoki, N.
Leukocytosis sometimes accompanies malignant neoplasms in the absence of infection. It is thought that the production of colony-stimulating factor by neoplasms is the most potent cause of...
Nakamura, M., Katano, M., Kuwahara, A., Fujimoto, K., Miyazaki, K., Morisaki, T., ...
It has been generally accepted that transforming growth factor beta1 (TGF-beta1) has both negative and positive effects on tumour growth and progression. This study analysed the prognostic value of...
P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo.
Abe, Y., Ohnishi, Y., Yoshimura, M., Ota, E., Ozeki, Y., Oshika, Y., ...
We examined whether the increased expression of P-glycoprotein (P-gp) encoded by the human multidrug resistance gene MDR1 is related to the acquired multidrug resistance of lung cancer in vivo. We...
Tokunaga, T., Oshika, Y., Abe, Y., Ozeki, Y., Sadahiro, S., Kijima, H., ...
Vascular endothelial growth factor (VEGF) is a well known factor that induces angiogenesis. Four isoforms, i.e. VEGF206, 189, 165, and 121, have been identified. We examined the isoform patterns of...
Takamiya, Y., Abe, Y., Tanaka, Y., Tsugu, A., Kazuno, M., Oshika, Y., ...
Human glioma usually shows intrinsic multidrug resistance because of the blood-brain barrier (BBB), in which membrane-associated P-glycoprotein (P-gp), encoded by the human multidrug resistance gene...
FADD phosphorylation is critical for cell cycle regulation in breast cancer cells
Matsuyoshi, S, Shimada, K, Nakamura, M, Ishida, E, Konishi, N
Anti-oestrogen therapy is effective for control of hormone receptor-positive breast cancers, although the detailed molecular mechanisms, including signal transduction, remain unclear. We demonstrated...
Ota, H, Nagano, H, Sakon, M, Eguchi, H, Kondo, M, Yamamoto, T, ...
We previously reported the beneficial effects of combination therapy of interferon (IFN)-α/5-fluorouracil (FU) for advanced hepatocellular carcinoma (HCC) with tumour thrombi in the major portal...
Tokunaga, T, Nakamura, M, Oshika, Y, Abe, Y, Ozeki, Y, Fukushima, Y, ...
Two subtypes of thrombospondin (TSP-1 and TSP-2) have inhibitory roles in angiogenesis in vitro, although the biological significance of these TSP isoforms has not been determined in vivo. We...
The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma
Ito, Y, Monden, M, Takeda, T, Eguchi, H, Umeshita, K, Nagano, H, ...
The status of Fas and Fas ligand (Fas L) expression was investigated in this study for 103 hepatocellular carcinomas (HCC). We studied the expression of the following three factors, Fas and Fas L...
Ribozyme-mediated inactivation of mutant K-ras oncogene in a colon cancer cell line
Tokunaga, T, Tsuchida, T, Kijima, H, Okamoto, K, Oshika, Y, Sawa, N, ...
Mutation of c-K-ras oncogene is an important step in progression of colon cancer. We used a hammerhead ribozyme (KrasRz) against mutated K-ras gene transcripts (codon 12, GTT) to inactivate mutant...
Overexpression of leucocyte common antigen (LAR) P-subunit in thyroid carcinomas
Konishi, N, Tsujikawa, K, Yamamoto, H, Ishida, E, Nakamura, M, Shimada, K, ...
Protein tyrosine phosphatase (PTPase) dephosphorylation and protein tyrosine kinase (PTKs) phosphorylation of key signal transduction proteins may be regulated by extracellular signals, making...