M. Peeters

Publication List Details

Period

1977 - 2009

Number

379

Co-Authors

Feasibility of radiotherapy with concomitant gemcitabine and oxaliplatin in locally advanced pancreatic cancer and distal cholangiocarcinoma: a prospective dose finding phase I-II study (2009)

Laurent, S., Monsaert, E., Boterberg, T., Demols, A., Borbath, I., Polus, M., ...

Background: The prognosis of pancreaticobiliary tumors is poor. The aim was to assess the feasibility of radiotherapy (RT) and concomitant gemcitabine and oxaliplatin in locally advanced pancreatic...

Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study (2009)

Van Cutsem, E., Rivera, F., Berry, S., Kretzschmar, A., Michael, M., DiBartolomeo, M., ...

Background: Bevacizumab significantly improves survival when added to chemotherapy for metastatic colorectal cancer (mCRC). The Bevacizumab Expanded Access Trial (BEAT) evaluated the safety and...

KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab (2008)

Piessevaux, H, De Schutter, Jef, Janssens, M, Personeni, N, ...

Background: KRAS mutation status is a candidate marker for predicting survival in patients with metastatic colorectal cancer (mCRC) treated with cetuximab (CTX).

KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab (2008)

De Roock, W., Piessevaux, H., De Schutter, J., Janssens, M., De Hertogh, G., Personeni, N., ...

Background: KRAS mutation status is a candidate marker for predicting survival in patients with metastatic colorectal cancer (mCRC) treated with cetuximab (CTX). Patients and methods: We studied the...

An open-label, single-arm study assessing safety and efficacy of panitumumab in patients with metastatic colorectal cancer refractory to standard chemotherapy (2008)

Van Cutsem, E., Siena, S., Humblet, Y., Maurel, J., Bajetta, E., ...

Background: A phase 3 study demonstrated that panitumumab, a human monoclonal anti-epidermal growth factor receptor antibody, significantly prolonged progression-free survival versus best supportive...

An open-label, single-arm study assessing safety and efficacy of panitumumab in patients with metastatic colorectal cancer refractory to standard chemotherapy (2007)

Siena, S, Humblet, Y, Canon, J-L, Maurel, J, Bajetta, E, ...

BACKGROUND: A phase 3 study demonstrated that panitumumab, a human monoclonal anti-epidermal growth factor receptor antibody, significantly prolonged progression-free survival versus best supportive...

Efficacy of the combination of long-acting release octreotide and tamoxifen in patients with advanced hepatocellular carcinoma: a randomised multicentre phase III study (2007)

Reynaert, H, Borbath, I, Langlet, P, Vandebroek, A, ...

To assess the efficacy of the combination of long-acting release (LAR) octreotide and tamoxifen (TMX) for the treatment of advanced hepatocellular carcinoma (HCC). A total of 109 patients with...

Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer (2007)

Machiels, J-P, Sempoux, C, Scalliet, P, Coche, J-C, Humblet, Y, Van Cutsem, E, ...

Background: To assess the safety and preliminary efficacy of concurrent radiotherapy, capecitabine, and cetuximab in the preoperative treatment of patients with rectal cancer. Patients and methods:...

Recombinant human erythropoietin alpha modulates the effects of radiotherapy on colorectal cancer microvessels (2007)

Boterberg, T, Smeets, P, Demetter, P, Zwaenepoel, O, ...

Recent data suggest that recombinant human erythropoietin (rhEPO) modulates tumour growth and therapy response. The purpose of the present study was to examine the modulation of radiotherapy (RT)...

Announcing a TAFIa mutant with a 180-fold increased half-life and concomitantly a strongly increased antifibrinolytic potential (2007)

Peeters, M

Laboratory for Pharmaceutical Biology, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium.

Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer (2007)

Machiels, J-P, Sempoux, C, Scalliet, P, Coche, J-C, Humblet, Y, Van Cutsem, Eric; U0003840, ...

BACKGROUND: To assess the safety and preliminary efficacy of concurrent radiotherapy, capecitabine, and cetuximab in the preoperative treatment of patients with rectal cancer. PATIENTS AND METHODS:...

Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer (2007)

Machiels, J-P, Sempoux, C, Scalliet, P, Coche, J-C, Humblet, Y, Van Cutsem, E, ...

Background: To assess the safety and preliminary efficacy of concurrent radiotherapy, capecitabine, and cetuximab in the preoperative treatment of patients with rectal cancer. Patients and methods:...

Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer (2007)

Machiels, J-P, Sempoux, C, Scalliet, P, Coche, J-C, Humblet, Y, Van Cutsem, E, ...

Background: To assess the safety and preliminary efficacy of concurrent radiotherapy, capecitabine, and cetuximab in the preoperative treatment of patients with rectal cancer. Patients and methods:...

Genetic and phylogenetic characterization of structural genes from non-B HIV-1 subtypes in Italy (2006)

Vidal, N, Tornesello, M L, Peeters, M, Buonaguro, F M, Buonaguro, L

A molecular and phylogenetic characterization on env and gag subgenomic regions has been performed in our laboratory on HIV-1 variants identified in seropositive individuals residing in Italy,...

Pre-operative combined modality therapy in the management of locally advanced rectal cancer (2006)

Pattyn, P, Boterberg, T, Peeters, M

AIMS: To review the use of pre-operative combined modality therapy (CMT, chemotherapy with radiotherapy) in the management of resectable rectal cancer. METHODS: A systematic search was performed on...

Gemcitabine and oxaliplatin (GEMOX) in gemcitabine refractory advanced pancreatic adenocarcinoma: a phase II study (2006)

Peeters, M, Marechal, R, Gay, F, Monsaert, E, ...

Gemcitabine and oxaliplatin (GEMOX) are active as first-line therapy against advanced pancreatic cancer. This study aims to evaluate the activity and tolerability of this combination in patients...

HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC) (2006)

Mulanga, C, Bazepeo, S Edidi, Mwamba, J Kasali, Tshimpaka, J, Kashi, M, ...

To study recombination and the natural polymorphism in pol of HIV-1 strains in the Democratic Republic of Congo (DRC) we sequenced the protease and RT genes for 70 HIV-1 strains previously...

Identification and molecular characterization of subsubtype A4 in central Africa (2006)

Mulanga, C, Bazepeo, S Edidi, Lepira, F, Delaporte, E, Peeters, M

Phylogenetic analysis on partial env sequences of HIV-1-positive samples obtained from sentinel population groups in HIV serosurveillance studies in 1997 and 2002 in the Democratic Republic of Congo...

Molecular characterization of a novel simian immunodeficiency virus lineage (SIVtal) from northern talapoins (Miopithecus ogouensis) (2006)

Courgnaud, V, Switzer, WM, Murphy, HW, Loul, S, Aghokeng, A, ...

Simian immunodeficiency viruses (SIVs) are found in an extensive number of African primates, and humans continue to be exposed to these viruses by hunting and handling of primate bushmeat and...

Antiretroviral drug resistance and routine therapy, Cameroon (2006)

Kouanfack, C, Vergne, L, Tardy, M, Zekeng, L, Noumsi, N, ...

Among 128 patients routinely receiving highly active antiretroviral therapy in an HIV/AIDS outpatient clinic in Cameroon, 16.4% had drug resistance after a median of 10 months. Of these, 12.5% had...

The dynamic adjustment towards target capital structures of firms in transition economies (2006)

Peeters, M

We examine the capital structure dynamics of Central and Eastern European firms to get a better understanding of the quantitative and qualitative development of the financial systems in this region....

Noninvasive monitoring of radiotherapy-induced microvascular changes using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in a colorectal tumor model (2006)

Smeets, P, Backes, W, Van Damme, Nancy, Boterberg, T, Demetter, P, ...

Purpose: To examine dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with a macromolecular contrast agent (P792) to visualize effects of radiotherapy (RT) on microvascular leakage in a...

Ex-prisoners, homelessness and the state in Australia (2006)

McDonnell, D, Maplestone, P, Peeters, M

Australia, with other OECD countries, has experienced a rapid rise in numbers of prison releasees. With this, there is heightened interest in the social impact of more prisoners returning to the...

Phylogenetic analysis of Brazilian HIV type 1 subtype D strains: Tracing the origin of this subtype in Brazil (2006)

Eyer-Silva, WA, Guimaraes, ML, Chequer-Fernandez, SL, Grinsztejn, B, Delaporte, E, ...

HIV-1 Subtype D occurs mainly in East and Central African countries, especially Uganda, where the prevalence of HIV-1 infection is among the highest in the world. We present the phylogenetic analysis...

Structure, food and shade attract juvenile coral reef fish to mangrove and seagrass habitats: a field experiment (2006)

Nagelkerken, I, De Graaff, D, Peeters, M, Bakker, EJ

Mangroves and seagrass beds are considered nurseries for juvenile fish, but little experimental evidence exists to elucidate which factors make them attractive habitats. A multifactorial field...

Influence of current noise on the relaxation oscillation dynamics of semiconductor lasers (2006)

Soriano, MC, Yousefi, M, Peeters, M, Danckaert, J, Verschaffelt, G, ...

We find experimentally that the relaxation oscillation peak in the relative intensity noise spectrum of a semiconductor laser has a higher damping and lower frequency when we add low frequency noise...

Transmission of simian immunodeficiency virus SIVcpz and the evolution of infection in the presence and absence of concurrent human immunodeficiency virus type 1 infection in chimpanzees (2006)

Rutjens, E, Verschoor, EJ, Niphuis, H, Ten Haaft, P, Rouse, S, ...

Current data suggest that the human immunodeficiency virus type 1 (HIV-1) epidemic arose by transmission of simian immunodeficiency virus (SIV) SIVcpz from a subspecies of common chimpanzees (Pan...

Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1 (2006)

Munch, J, Kutsch, O, Li, H, Santiago, ML, Bibollet-Ruche, F, ...

High-level immune activation and T cell apoptosis represent a hallmark of HIV-1 infection that is absent from nonpathogenic SIV infections in natural primate hosts. The mechanisms causing these...

Sensitivity of three serum antibody tests in a large outbreak of Legionnaires' disease in the Netherlands (2006)

Den Boer, JW, Lettinga, KD, Schel, AJ, Schellekens, J, Peeters, M

In 1999, an outbreak involving 188 patients with Legionnaires' disease (LD) occurred at a flower show in the Netherlands. This large outbreak provided the opportunity to evaluate serum antibody tests...

Natural polymorphism in protease and reverse transcriptase genes and in vitro antiretroviral drug susceptibilities of non-B HIV-1 strains from treatment-naive patients (2006)

Stuyver, L, Van Houtte, M, Butel, C, Delaporte, E, Peeters, M

Background: Most studies on antiretroviral (ARV) resistance of human immunodeficiency virus (HIV) have been done on subtype B which only represent a limited proportion of infections worldwide.

Tactile spatial attention enhances gamma-band activity in somatosensory cortex and reduces low-frequency activity in parieto-occipital areas (2006)

Oostenveld, R, Peeters, M, Fries, P

We investigated the effects of spatial-selective attention on oscillatory neuronal dynamics in a tactile delayed-match-to-sample task. Whole-head magnetoencephalography was recorded in healthy...

Gas productivity related to cleat volumes derived from focused resistivity tools in coalbed methane (CBM) fields (2006)

Peeters, M, Cloud, TA, Van Kirk, CW

Cleats are critical for coal-bed methane (CBM) production, but operators usually lack a viable method to determine productivity except for costly well tests. Wireline logs, run over the CBM deposits...

Widely varying SIV prevalence rates in naturally infected primate species from Cameroon (2006)

Liu, WM, Bibollet-Ruche, F, Loul, S, Mpoudi-Ngole, E, Laurent, C, ...

Although it is now well established that a substantial proportion of wild-living primates in sub-Saharan Africa harbor SIV, no study to date has examined to what extent the various species are...

Modulation of TAFI function through different pathways - implications for the development of TAFI inhibitors (2005)

Gils, Ann; U0005633, Ceresa, Erik; U0042016, Macovei, AM, Marx, PF, Peeters, M, Compernolle, G, ...

Objective: To elucidate the mechanism and the binding regions of monoclonal antibodies (MA) that interfere with thrombin-activatable fibrinolysis inhibitor (TAFI)/activated thrombin-activatable...

Optimization of a genotypic assay applicable to all human immunodeficiency virus type 1 protease and reverse transcriptase subtypes (2005)

Riva, C, Steegen, K, Schrooten, Yoeri, Maes, Bart, Vergne, L, ...

Genotypic assays are used often to guide clinicians in decisions concerning the treatment of patients. An optimized sequence-based genotypic assay was used to determine the whole protease and reverse...

A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer (2005)

Richards, D, Ramanathan, R K, Van Laethem, J L, Peeters, M, Fuchs, M, ...

BACKGROUND: This randomized phase III study compared the overall survival (OS) of pemetrexed plus gemcitabine (PG) versus standard gemcitabine (G) in patients with advanced pancreatic cancer....

Distribution of HIV-1 variants in the Democratic Republic of Congo suggests increase of subtype C in Kinshasa between 1997 and 2002 (2005)

Mulanga, C, Bazepeo, SE, Mwamba, JK, Tshimpaka, JW, Kashi, M, ...

The Democratic Republic of Congo (DRC) is characterized by low and stable HIV prevalences and high HIV-1 genetic diversity and is most probably the epicenter of HIV-1 group M. Our major goal was to...

Enfuvirtide binding domain is highly conserved in non-B HIV type 1 strains from Cameroon, West Central Africa (2005)

Ewane, L, Awazi, B, Nanfack, A, Delaporte, E, Zekeng, L, ...

Recently T-20 or enfuvirtide, the first drug of a new class of antiretrovirals targeting the entry stage of the virus life cycle, has been clinically approved. Enfuvirtide is a peptide derived from...

An equivalence test for comparing DNA sequences (2005)

Raby, BA, Molenberghs, G, Thijs, H, De Wit, M, Peeters, M

The practice of sequence alignment is constantly oscillating between the risk of overlooking important structure and that of discovering any arbitrarily defined kind of structure anywhere. On the...

Simian immunodeficiency virus infection in free-ranging sooty Mangabeys (Cercocebus atys atys) from the Tai Forest, Cote d'Ivoire: Implications for the origin of epidemic human immunodeficiency virus type 2 (2005)

Range, F, Keele, BF, Li, YY, Bailes, E, Bibollet-Ruche, F, ...

Simian immunodeficiency virus of sooty mangabeys (SIVsmm) is recognized as the progenitor of human immunodeficiency virus type 2 (HIV-2) and has been transmitted to humans on multiple occasions, yet...

Can we obtain invasion depth with directional borehole radar? (2005)

Peeters, M

We examine whether directional borehole radar while drilling is a feasible method to detect the fluid interface that forms when mud filtrate invades a permeable layer. This interface should be...

Sloping invasion profiles derived from shallow wireline logs (2005)

Peeters, M

Invasion affects all wireline logs, especially the logs of shallow reading tools. Although tool responses can be predicted with tool models, even sophisticated log analysis programs usually apply...

TMC114/ritonavir substitution for protease inhibitor(s) in a non-suppressive antiretroviral regimen: a 14-day proof-of-principle trial (2005)

Clumeck, N, Pozniak, A, Lazzarin, A, De Meyer, S, Muller, H, ...

Objective: To evaluate antiviral activity, tolerability, and safety of the protease inhibitor (PI) TMC114 boosted with low-dose ritonavir (RTV). Design: A randomized, open-label, controlled, phase...

Antigenic conservation and immunogenicity of the HIV coreceptor binding site (2005)

Bibollet-Ruche, F, Wei, XP, Wang, SY, Levy, DN, Wang, WQ, ...

Immunogenic, broadly reactive epitopes of the HIV-1 envelope glycoprotein could serve as important targets of the adaptive humoral immune response in natural infection and, potentially, as components...

Multi-agent Reinforcement Learning in stochastic single and multi-stage games (2005)

Nowe, A, Peeters, M, Tuyls, K

In this paper we report on a solution method for one of the most challenging problems in Multi-agent Reinforcement Learning, i.e. coordination. In previous work we reported on a new coordinated...

Development, technical performance, and clinical evaluation of a NucliSens basic kit application for detection of enterovirus RNA in cerebrospinal fluid (2005)

Zhang, F, Malhotra, A, Manji, R, Sillekens, P, Foolen, H, ...

The combination of nucleic acid sequence-based amplification and electrochemiluminescence detection was used to develop an internally controlled, highly sensitive and specific assay for the detection...

The influence of the M184V mutation in HIV-1 reverse transcriptase on the virological outcome of highly active antiretroviral therapy regimens with or without didanosine (2005)

Pozniak, AL, Peeters, M, Winters, B, Hoetelmons, R, Graham, NM, ...

Background: In vitro phenotypic resistance studies suggest that the presence of the M184V mutation leads to a reduction in HIV-1 susceptibility to didanosine (ddl). The relevance of this to clinical...

Presence of CRF09_cpx and complex CRF02_AG/CRF09_cpx recombinant HIV type 1 strains in Cote d'Ivoire, West Africa (2005)

Adje-Toure, C, Vidal, N, Minga, A, Huet, C, Borger, MY, ...

Based on partial env and pol (protease and RT) subtyping, we recently documented that the majority (> 80%) of the HIV-1 strains that circulate in Cote d'Ivoire were CRF02_AG and about 11% were...

A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer (2005)

Oettle, H., Richards, D., Ramanathan, R. K., Van Laethem, J. L., Peeters, M., Fuchs, M., ...

Background: This randomized phase III study compared the overall survival (OS) of pemetrexed plus gemcitabine (PG) versus standard gemcitabine (G) in patients with advanced pancreatic cancer....

A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer (2005)

Oettle, H., Richards, D., Ramanathan, R. K., Van Laethem, J. L., Peeters, M., Fuchs, M., ...

Background: This randomized phase III study compared the overall survival (OS) of pemetrexed plus gemcitabine (PG) versus standard gemcitabine (G) in patients with advanced pancreatic cancer....

Genome wide scan in a Flemish inflammatory bowel disease population: support for the IBD4 locus, population heterogeneity, and epistasis (2004)

Van Steen, K, Claessens, G, ...

BACKGROUND AND AIMS: Genome wide scans in inflammatory bowel disease (IBD) have indicated various susceptibility regions with replication of 16cen (IBD1), 12q (IBD2), 6p (IBD3), 14q11 (IBD4), and...

Raltitrexed plus gemcitabine (TOMGEM) in advanced pancreatic cancer. Results of a Belgian multicentre phase II study (2004)

Van Maele, Ph, Demols, A, Houbiers, Gh, ...

OBJECTIVES: This multicenter phase II study was designed to determine the activity and tolerance of gemcitabine and raltitrexed in advanced pancreatic adenocarcinoma. PATIENTS AND METHODS:...

HIV-1 superinfections in a cohort of commercial sex workers in Burkina Faso as assessed by an autologous heteroduplex mobility procedure (2004)

Courgnaud, V, Sanou, O, Valea, D, Nagot, N, Meda, N, ...

Objective: To describe and evaluate a simple procedure to identify HIV-1 co- or super-infections based on a heteroduplex mobility assay (HMA).

Is the perceived association between Chlamydia pneumoniae and vascular diseases biased by methodology? (2004)

Berg, H, Kerver, M, Kranendonk, S, Hamming, J, Kluytmans, J, ...

Inter- and intralaboratory inconsistencies in detection rates of Chlamydia pneumoniae in vascular specimens have been demonstrated. In this study, 66 vascular tissue specimens from 66 patients with...

Evaluation of four simple/rapid assays and two fourth-generation ELISAs for the identification of HIV infection on a serum panel representing the HIV-1 group M genetic diversity in Cameroon (2004)

Ewane, LO, Awazi, B, Nanfack, A, Delaporte, E, Peeters, M, ...

The performance of 4 rapid and simple assays: Camstix-HIV 1+2 (Camdiagnostix, Yaounde, Cameroon); Determine HIV 1+2+0 (Abbott Laboratories, Tokyo, Japan); Genie II HIV-1/HIV-2 (Bio-Rad, Marnes la...

Effectiveness and safety of a generic fixed-dose combination of nevirapine, stavudine, and lamivudine in HIV-1-infected adults in Cameroon: open-label multicentre trial (2004)

Kouanfack, C, Koulla-Shiro, S, Nkoue, N, Bourgeois, A, Calmy, A, ...

Background Generic fixed-dose combinations have been prequalified by WHO to treat HIV-infected patients in resource-limited countries. Despite their widespread use they are, however, not yet...

A screening strategy for the development of enantiomeric separation methods in capillary electrophoresis (2004)

Jimidar, ML, Van Ael, W, Van Nyen, P, Peeters, M, Redlich, D, De Smet, M

Method development of enantiomeric separations in capillary electrophoresis (CE) is a time-consuming task, since finding the appropriate chiral selector is usually a "trial and error" process. It is...

New simian immunodeficiency virus infecting De Brazza's monkeys (Cercopithecus neglectus): Evidence for a Cercopithecus monkey virus clade (2004)

Bailes, E, Gao, F, Pourrut, X, Barlow, KL, Clewley, JP, ...

Nearly complete sequences of simian immunodeficiency viruses (SIVs) infecting 18 different nonhuman primate species in sub-Saharan Africa have now been reported; yet, our understanding of the...

Metastatic follicular dendritic cell sarcoma of the stomach : A case report and review of the literature (2004)

Geerts, A, Lagae, E, Dhaene, K, Peeters, M, Waeytens, A, Demetter, P, ...

Follicular dendritic cell (FDC) sarcomas are rare tumours, typically seen in lymph nodes. However, in about one third of the reported cases, a FDC sarcoma presents as an extranodal mass. Involvement...

Simian T-cell leukemia virus (STLV) infection in wild primate populations in Cameroon: Evidence for dual STLV type 1 and type 3 infection in agile mangabeys (Cercocebus agilis) (2004)

Liegeois, F, Pourrut, X, Abela, B, Loul, S, ...

Three types of human T-cell leukemia virus (HTLV)-simian T-cell leukemia virus (STLV) (collectively called primate T-cell leukemia viruses [PTLVs]) have been characterized, with evidence for zoonotic...

Commercial logging and HIV epidemic, rural equatorial Africa (2004)

Bourgeois, A, Mpoudi, M, Butel, C, Peeters, M, Mpoudi-Ngole, E, ...

We found a high seroprevalence of HIV among young women in a commercial logging area in Cameroon. The vulnerability of these young women could be related to commercial logging and the social and...

Complete genome analysis of one of the earliest SIVcpzPtt strains from Gabon (SIVcpzGAB2) (2004)

Gao, F, Bailes, E, Saragosti, S, Delaporte, E, Peeters, M, ...

Chimpanzees in west central Africa ( Pan troglodytes troglodytes) are known to harbor simian immunodeficiency viruses (SIVcpzPtt) that represent the closest relatives of human immunodeficiency virus...

One-mode model for patterned metal layers inside integrated color pixels (2004)

Suh, WJ, Fan, SH, Peeters, M

Optimized design of the optical filters inside integrated color pixels (ICPs) for complementary metal-oxide semiconductor image sensors requires analytical models. ICP optical filters consist of...

Stochastic polarization switching dynamics in vertical-cavity surface-emitting lasers: Theory and experiment (2004)

Peeters, M, Mirasso, C, Miguel, MS, Verschaffelt, G, Albert, J, ...

We present an analytical, numerical, and experimental study of the switching time and jitter of current-induced polarization switching in vertical-cavity surface-emitting lasers (VCSELs) as an...

Waveguiding effects in self-pulsing vertical-cavity surface-emitting lasers (2004)

Panajotov, K, Peeters, M, Veretennicoff, I, Danckaert, J, Erneux, T

Self-pulsing in semiconductor lasers containing a saturable absorber is well documented. We propose an alternative mechanism leading to self-pulsing in vertical-cavity surface-emitting lasers. We...

Encephalopathy associated with influenza A (2004)

Stroink, H, Bruinenberg, JFM, Peeters, M

We report a 3-year-old boy with influenza A virus-associated encephatopathy. The diagnosis was based on clinical findings, magnetic resonance imaging, repeated isolation of influenza A virus from...

Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B (2004)

Vergne, L, Peeters, M, Reynes, J, Delaporte, E, Segondy, M

Objective: To compare the prevalence of mutations associated with resistance to antiretroviral drugs and their interpretation in patients infected with non-B HIV-1 variants versus HIV-1 subtype...

Are carcinomas of the cardia oesophageal or gastric adenocarcinomas? (2003)

Peeters, M, ...

There is a clear relationship between Barrett's oesophagus and oesophageal adenocarcinoma, and between Helicobacter pylori and gastric cancer, but the histogenesis of cardiac adenocarcinomas is...

Anti-saccharomyces cerevisiae IgA antibodies are raised in ankylosing spondylitis and undifferentiated spondyloarthropathy (2003)

Demetter, P, Peeters, M, De Vos, M, Mielants, H, Veys, E M, ...

OBJECTIVES: To investigate whether anti-Saccharomyces cerevisiae antibodies (ASCA), a marker for Crohn's disease (CD), are present in spondyloarthropathies (SpA) and in the subgroups ankylosing...

Reduced transmission and prevalence of simian T-cell lymphotropic virus in a closed breeding colony of chimpanzees (Pan troglodytes verus) (2003)

Verschoor, E J, Bontjer, I, Peeters, M, Heeney, J L

A retrospective study spanning 20 years was undertaken to investigate the prevalence and modes of transmission of a simian T-cell lymphotropic virus (STLV) in a closed breeding colony of chimpanzees....

Partial molecular characterization of two simian immunodeficiency viruses (SIV) from African colobids: SIVwrc from western red colobus (Piliocolobus badius) and SIVolc from olive colobus (Procolobus verus) (2003)

Formenty, P, Akoua-Koffi, C, Noe, R, Boesch, C, Delaporte, E, ...

In order to study primate lentivirus evolution in the Colobinae subfamily, in which only one simian immunodeficiency virus (SIV) has been described to date, we screened additional species from the...

Frequency response of polarization switching in vertical-cavity surface-emitting lasers (2003)

Albert, J, Nagler, B, Peeters, M, Danckaert, J, Barbay, S, ...

We present an experimental study of the current-driven polarization modulation properties of VCSELs. In some VCSELs, abrupt polarization switching (PS) between two polarization modes is observed at a...

Low rate of genotypic HIV-1 drug-resistant strains in the Senegalese government initiative of access to antiretroviral therapy (2003)

Kane, CT, Laurent, C, Diakhate, N, Gueye, NFN, Gueye, PM, ...

Objective: To monitor the prevalence of antiretroviral (ARV)-resistant HIV-1 viruses, and the genotypic mutations in patients enrolled in the Senegalese initiative for access to antiretroviral...

Prevalence of genotypic and phenotypic HIV-1 drug-resistant strains among patients who have rebound in viral load while receiving antiretroviral therapy in the UNAIDS-Drug Access Initiative in Abidjan, Cote d'Ivoire (2003)

Celestin, B, Hanson, D, Roels, TH, Hertogs, K, Larder, B, ...

Objective: To determine the prevalence of genotypic and phenotypic antiretroviral (ARV) drug-resistant HIV-1 strains among patients with viral load rebound while receiving ARV therapy in Abidjan,...

High genetic diversity of HIV-1 strains in Chad, West Central Africa (2003)

Koyalta, D, Richard, V, Lechiche, C, Ndinaromtan, T, Djimasngar, A, ...

The genetic diversity of HIV-1 strains in Chad was documented with a total of 107 samples from patients attending the general hospital in N'Djamena, the capital city of Chad. The genetic subtypes...

Polarization-mode hopping in single-mode vertical-cavity surface-emitting lasers: Theory and experiment (2003)

Peeters, M, Albert, J, Verschaffelt, G, Panajotov, K, Thienpont, H, ...

In this paper, we present a theoretical and experimental analysis of stochastic effects observed in polarization switching vertical-cavity surface-emitting lasers. We make a thorough comparison...

Biological and genetic characteristics of HIV infections in Cameroon reveals dual group M and O infections and a correlation between SI-inducing phenotype of the predominant CRF02_AG variant and disease stage (2003)

Bourgeois, A, Mpoudi-Ngole, E, Mougnutou, R, Mbuagbaw, J, Liegeois, F, ...

In Yaounde, Cameroon, HIV-1 group-specific V3 serology on 1469 HIV-positive samples collected between 1996 and 2001 revealed that group O infections remained constant around 1% for 6 years. Only one...

Optimal integer solutions to industrial cutting-stock problems: Part 2, benchmark results (2003)

Peeters, M

In this paper we present a state-of-the-art version of the branch-and-price procedure of Degraeve and Schrage (1999) for the exact solution of the cutting-stock problem. The average solution time is...

TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen (2003)

Weverling, GJ, Peeters, M, Van't Klooster, G, Gruzdev, B, Rakhmanova, A, ...

Objective: TMC125, a next generation, non-nucleoside reverse transcriptase inhibitor (NNRTI), demonstrated a remarkable decline of plasma HIV-1 RNA during a phase IIa study. We compared the initial...

An open-label assessment of TMC 125-a new, next-generation NNRTI, for 7 days in HIV-1 infected individuals with NNRT1 resistance (2003)

Pozniak, AL, Rosenbaum, W, Yeni, GP, Staszewski, S, Arasteh, K, ...

The development of resistance to any of the currently licensed non-nucleoside reverse transcriptase inhibitors (NNRTI) invariably leads to cross-resistance to the drugs in that class. New NNRTI, that...

Emergence of complex and diverse CRF02-AG/CRF06-cpx recombinant HIV type 1 strains in Niger, West Africa (2003)

Vidal, N, Montavon, C, Ben, A, Djibo, A, Rabiou, S, ...

On the basis of partial env and gag subtyping, we documented that the majority of HIV-1 strains circulating in Niger were CRF02-AG (54.3%) or CRF06-cpx (18.1%) and that 9% of the samples were...

Identification of a new simian immunodeficiency virus lineage with a vpu gene present among different Cercopithecus monkeys (C-mona, C-cephus, and C-nictitans) from Cameroon (2003)

Abela, B, Pourrut, X, Mpoudi-Ngole, E, Loul, S, Delaporte, E, ...

During a large serosurvey of wild-caught primates from Cameroon, we found 2 mona monkeys (Cercopithecus mona) out of 8 and 47 mustached monkeys (Cercopithecus cephus) out of 302 with human...

A randomized, double-blind, placebo-controlled trial of TMC125 as 7-day monotherapy in antiretroviral naive, HIV-1 infected subjects (2003)

Rakhmanova, A, Doubovskaya, E, Yakovlev, A, Peeters, M, Rinehart, A, ...

Objective: To evaluate antiviral activity, tolerability, safety and pharmacokinetics of treatment with TMC125 (a non-nucleoside reverse transcriptase inhibitor), 900 mg twice daily for 7 days.

CRF06-cpx is the predominant HIV-1 variant in AIDS patients from Ouagadougou, the capital city of Burkina Faso (2003)

Montavon, C, Sanou, T, Vidal, N, Sangare, L, Sanou, I, ...

No data on HIV-1 genetic subtypes in Burkina Faso have yet been reported. Among 70 samples obtained in 2001, the predominant env subtype was CRF06-cpx, followed by CRT02-AG, subtypes A and G....

Radiolabelled thymidines and deoxyuridines for measuring cellular proliferation in tumours--an update (2002)

De Bondt, P, Peeters, M, Vermeersch, H, Dierckx, R A

Radiolabelled thymidines and deoxyuridines for measuring cellular proliferation in tumours - an update.

Development and evaluation of a DNA enzyme immunoassay method for env genotyping of subtypes A through G of human immunodeficiency virus type 1 group M, with discrimination of the circulating recombinant forms CRF01_AE and CRF02_AG (2002)

Plantier, JC, Vergne, L, Damond, F, MBoup, S, MPoudi-NGole, E, Buzelay, L, ...

The tools currently available for genetic subtyping of human immunodeficiency virus type I are laborious or can be used only for the analysis of a limited number of samples and/or subtypes. We...

Sensitivity of three urinary antigen tests associated with clinical severity in a large outbreak of Legionnaires' disease in the Netherlands (2002)

Yzerman, EPF, Den Boer, JW, Lettinga, KD, Schellekens, J, Dankert, J, Peeters, M

In 1999 an outbreak involving 188 patients with Legionnaires' disease (LD) occurred among visitors to a flower show in the Netherlands. Two enzyme immunoassays (Binax and Biotest) and one...

CRF06-cpx: A new circulating recombinant form of HIV-1 in West Africa involving subtypes A, G, K, and J (2002)

Montavon, C, Toure-Kane, C, Nkengasong, JN, Vergne, L, Hertogs, K, Mboup, S, ...

Phylogenetic analysis of numerous strains of HIV-1 isolated from diverse geographic origins has revealed three distinct groups of HIV-1: groups M, N, and O, Within group M, sub-subtypes and...

Resistance to antiretroviral treatment in Gabon: Need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries (2002)

Vergne, L, Malonga-Mouellet, G, Mistoul, I, Mavoungou, R, Mansaray, H, Peeters, M, ...

The protease and reverse transcriptase (RT) genes were studied in antiretroviral (ARV)-experienced and drug-naive HIV-1-infected individuals in Libreville, Gabon. We have shown, although on a limited...

Risk to human health from a plethora of Simian immunodeficiency viruses in primate bushmeat (2002)

Peeters, M, Courgnaud, V, Abela, B, Auzel, P, Pourrut, X, Bibollet-Ruche, F, ...

To assess human exposure to Simian immunodeficiency virus (SIV) in west central Africa, we looked for SIV infection in 788 monkeys that were hunted in the rainforests of Cameroon for bushmeat or kept...

Hypersensitivity of dopamine transmission in the rat striatum after treatment with the NMDA receptor antagonist amantadine (2002)

Peeters, M, Page, G, Maloteaux, JM, Hermans, E

Amantadine, a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist known to increase dopamine synthesis and release in the striatum, is frequently associated with L-DOPA in the treatment...

Identification of a new circulating recombinant form of HIV type 1, CRF11-cpx, involving subtypes A, G, J, and CRF01-AE, in Central Africa (2002)

Montavon, C, Vergne, L, Bourgeois, A, Mpoudi-Ngole, E, Malonga-Mouellet, G, Butel, C, ...

In this study, we characterized three full-length genome sequences with a similar mosaic structure from epidemiologically unlinked individuals from Cameroon (97CM-MP818) and the Central African...

Expression of the Ly-6A (Sca-1) lacZ transgene in mouse haematopoietic stem cells and embryos (2002)

Ma, XQ, De Bruijn, M, Robin, C, Peeters, M, De Wit, T, ...

The Sca-1 surface glycoprotein is used routinely as a marker for haematopoietic stem cell enrichment. Two allelic genes, Ly-6A and Ly-6E, encode this marker and appear to be differentially regulated...

Full-length genome sequencing of HIV type 1 group O viruses isolated from a heterosexual transmission cluster in Senegal (2001)

Kane, C T, Montavon, C, Toure, M A, Faye, M A, Ndiaye, A G, Diallo, A G, ...

In a polygamous marriage in Senegal, the husband and his two spouses were infected with HIV-1 group O. This study provides new full-length genome sequences for the two spouses (99SE-MP1299 and...

Using human immunodeficiency virus type 1 sequences to infer historical features of the acquired immune deficiency syndrome epidemic and human immunodeficiency virus evolution (2001)

Yusim, K, Peeters, M, Pybus, O G, Bhattacharya, T, Delaporte, E, Mulanga, C, ...

In earlier work, human immunodeficiency virus type 1 (HIV-1) sequences were analysed to estimate the timing of the ancestral sequence of the main group of HIV-1, the virus that is responsible for the...

The genetic variability of HIV-1 and its implications (2001)

Peeters, M

UR36, Laboratoire Retrovirus, IRD, Montpellier, France. martine.peeters@mpl.ird.fr

Unexplained rising carcinoembryonic antigen (CEA) in the postoperative surveillance of colorectal cancer: the utility of positron emission tomography (PET) (2001)

Flamen, P, Hoekstra, O S, Homans, F, Van Cutsem, Eric; U0003840, Maes, Alex; U0032501, Stroobants, S, ...

The aim of the study was to evaluate the use of positron emission tomography with [18F]-fluorodeoxyglucose (FDG-PET) in patients with unexplained rising carcinoembryonic antigen (CEA) in the...

Intravenous cyclosporine versus intravenous corticosteroids as single therapy for severe attacks of ulcerative colitis (2001)

D'Haens, G, Lemmens, L, Geboes, K, Vandeputte, L, Van Acker, F, ...

BACKGROUND & AIMS: Cyclosporine has been effective in patients with steroid-refractory attacks of ulcerative colitis (UC). We investigated the effects of intravenous (IV) cyclosporine as single IV...

Human immunodeficiency virus. Phylogeny and the origin of HIV-1 (2001)

Robertson, D L, Pybus, O G, Peeters, M, Holmes, E C

Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK.

High prevalence of genotypic and phenotypic HIV-1 drug-resistant strains among patients receiving antiretroviral therapy in Abidjan, Côte d'Ivoire (2001)

Cheingsong, R, Roels, T H, Maurice, C, Djomand, G, ...

To describe prevalence of antiretroviral (ARV) drug-resistant HIV-1 strains among patients with a history of earlier treatment with ARV drugs in Abidjan, Côte d'Ivoire, we determined mutations that...

Anti-Saccharomyces cerevisiae antibodies (ASCA), phenotypes of IBD, and intestinal permeability: a study in IBD families (2001)

Peeters, M, ...

BACKGROUND: Serologic markers anti-Saccharomyces cerevisiae antibodies (ASCA) and antineutrophil cytoplasmic antibodies with perinuclear staining (pANCA) have been proposed to study the...

Comparative study of ASCA (Anti-Saccharomyces cerevisiae antibody) assays in inflammatory bowel disease (2001)

Peeters, M, Monsuur, F, Marien, G, ...

BACKGROUND & AIMS: Anti-Saccharomyces cerevisiae antibody (ASCA) is a serologic marker associated with Crohn's disease (CD). Although there is still discussion on its clinical value, several...

Evidence for inflammatory bowel disease of a susceptibility locus on the X chromosome (2001)

Satsangi, J, Peeters, M, Parkes, M, Jewell, D P, ...

BACKGROUND & AIMS: The technique of genomewide scanning has been applied successfully in inflammatory bowel disease (IBD). A number of putative susceptibility loci have been identified through...

A randomized, double-blind, placebo-controlled study of itraconazole capsules for the prevention of deep fungal infections in immunodeficient patients with HIV infection (2001)

Smith, D E, Bell, J, Johnson, M, Youle, M, Gazzard, B, Tchamouroff, S, ...

OBJECTIVES: To determine whether systemic or deep fungal infections can be prevented, a double-blind, placebo-controlled, phase III trial of itraconazole prophylaxis was undertaken in HIV-infected...

Dating the common ancestor of SIVcpz and HIV-1 group M and the origin of HIV-1 subtypes using a new method to uncover clock-like molecular evolution (2001)

Salemi, Marco; U0008167, Strimmer, K, Hall, W W, Duffy, Maria; U0035072, Delaporte, E, Mboup, S, ...

Attempts to estimate the time of origin of human immunodeficiency virus (HIV)-1 by using phylogenetic analysis are seriously flawed because of the unequal evolutionary rates among different viral...

Inflammatory bowel disease in spouses and their offspring (2001)

Laharie, D, Debeugny, S, Peeters, M, Van Gossum, Anna; U0021047, Gower-Rousseau, C, Bélaïche, J, ...

BACKGROUND & AIMS: The rarity of inflammatory bowel disease (IBD) in both husband and wife is often given as an argument against an infectious origin. We registered conjugal instances of IBD in...

Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes (2001)

Page, G, Peeters, M, Najimi, M, Maloteaux, J M, Hermans, E

There is considerable evidence that the activity of the neuronal dopamine transporter (DAT) is dynamically regulated and a putative implication of its phosphorylation in this process has been...

Tc-99m HMPAO white blood cell scintigraphy in the assessment of the extent and severity of an acute exacerbation of ulcerative colitis (2001)

Bennink, R, Peeters, M, D'Haens, G, Rutgeerts, Paul; U0007636

PURPOSE: Ulcerative colitis (UC) is a chronic inflammatory bowel disease with frequent exacerbations, including the risk for toxic megacolon and severe complications. In very active disease,...

Detection of Chlamydia pneumoniae DNA in buffy-coat samples of patients with abdominal aortic aneurysm (2001)

Maraha, B, Den Heijer, M, Wullink, M, Bergmans, A, Verbakel, H, ...

Recent studies have suggested that Chlamydia pneumoniae infection is a risk factor for abdominal aortic aneurysm. This study explores the presence of Chlamydia pneumoniae DNA in buffy-coat samples of...

Role of the high affinity immunoglobulin E receptor in bacterial translocation and intestinal inflammation (2001)

Dombrowicz, D, Nutten, S, Desreumaux, P, Neut, C, Torpier, G, Peeters, M, ...

A role for immunoglobulin E and its high affinity receptor (Fc epsilon RI) in the control of bacterial pathogenicity and intestinal inflammation has been suggested, but relevant animal models are...

Characterization of a novel simian immunodeficiency virus from guereza colobus monkeys (Colobus guereza) in Cameroon: a new lineage in the nonhuman primate lentivirus family (2001)

Courgnaud, V, Pourrut, X, Bibollet-Ruche, F, Mpoudi-Ngole, E, Bourgeois, A, Delaporte, E, ...

Exploration of the diversity among primate lentiviruses is necessary to elucidate the origins and evolution of immunodeficiency viruses. During a serological survey in Cameroon, we screened 25...

Correlation between detection methods of Chlamydia pneumoniae in atherosclerotic and non-atherosclerotic tissues (2001)

Maraha, B, Berg, H, Scheffer, GJ, Bergmans, A, Misere, J, ...

Polymerase chain reaction (PCR) and immunohistochemistry (IHC) have been used to detect Chlamydia (C.) pneumoniae in vascular tissues. Discrepancies between the results of these two methods have...

Patterns of resistance mutations to antiretroviral drugs in extensively treated HIV-1-infected patients with failure of highly active antiretroviral therapy (2001)

Vergne, L, Montes, B, Peeters, M, Reynes, J, Delaporte, E, ...

Resistance-mutation patterns in the reverse transcriptase (RT) and protease genes of HIV-1 were analyzed in 22 patients who had been extensively pretreated and who failed to respond to highly active...

Polarisation switching in vertical-cavity surface-emitting lasers: from experimental observations to applications (2001)

Verschaffelt, G, Panajotov, K, Albert, J, Nagler, B, Peeters, M, Danckaert, J, ...

Touted as promising components for present and future data-communication and sources for photonic switching fabrics, vertical-cavity surface-emitting lasers (VCSELs) have been studied in detail...

Physical reservoir models: from pictures to properties (2001)

Peeters, M

Petrophysics and geophysics have not always worked together as closely as one might expect. This paper discusses current advances and sketches future developments. The major objective of geophysical...

Exclusion of linkage of Crohn's disease to previously reported regions on chromosomes 12, 7, and 3 in the Belgian population indicates genetic heterogeneity (2000)

Peeters, M, Parkes, M, Satsangi, J, ...

Susceptibility to inflammatory bowel disease (IBD) is significantly determined by genetic factors. Linkage data from genome-wide searches have identified regions on chromosomes 16, 12, 7, and 3. Our...

The utility of positron emission tomography for the diagnosis and staging of recurrent esophageal cancer (2000)

Cambier, J P, ...

OBJECTIVE: To study the utility of whole-body positron emission tomography with (18)F-fluoro-deoxy-D -glucose (FDG-PET) for the evaluation of recurrence after curative resection of cancer of the...

Identification of a complex env subtype E HIV type 1 virus from the democratic republic of congo, recombinant with A, G, H, J, K, and unknown subtypes (2000)

Vidal, N, Mulanga-Kabeya, C, Nzilambi, N, Delaporte, E, Peeters, M

Up to now, all known env subtype E viruses (CRF01-AE) have had the same mosaic structure with subtype A, and no other env subtype E HIV-1 viruses with non-A subtypes in their genomes have been...

Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients (2000)

Vergne, L, Peeters, M, Mpoudi-Ngole, E, Bourgeois, A, Liegeois, F, Toure-Kane, C, ...

Most human immunodeficiency virus (HIV) drug susceptibility studies have involved subtype B strains. Little information on the impact of viral diversity on natural susceptibility to antiretroviral...

Multifocal epithelioid angiosarcoma of the small intestine (2000)

Delvaux, V, Sciot, Raphael; U0010292, Neuville, B, Peeters, M, ...

A 67-year-old man presented with weight loss, intermittent severe abdominal pain and melaena. Initial radiology (including abdominal ultrasonography), gastroscopy and colonoscopy did not demonstrate...

Utility of positron emission tomography for the staging of patients with potentially operable esophageal carcinoma (2000)

Peeters, M, ...

PURPOSE: A prospective study of preoperative tumor-node-metastasis staging of patients with esophageal cancer (EC) was designed to compare the accuracy of 18-F-fluoro-deoxy-D-glucose (FDG) positron...

Oral fluoropyrimidines in colorectal cancer (2000)

Peeters, M

Department of Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium.

Increased dopamine uptake in striatal synaptosomes after treatment of rats with amantadine (2000)

Page, G, Peeters, M, Maloteaux, J M, Hermans, E

The aim of the present study was to investigate the effect of short- and long-term treatments with amantadine on the activity of the neuronal dopamine transporter (DAT) in the rat striatum. For this...

The effects of smoking and indomethacin on small intestinal permeability (2000)

Suenaert, Peter; U0019635, Bulteel, Veerle; U0012256, Hiele, Martin; U0011266, Peeters, M, Monsuur, F, ...

BACKGROUND: Smoking modulates inflammatory bowel disease, protecting from ulcerative colitis on the one hand and worsening the course of Crohn's disease on the other. This influence might occur...

Most env and gag subtype A HIV-1 viruses circulating in West and West Central Africa are similar to the prototype AG recombinant virus IBNG (2000)

Toure-Kane, C, Liegeois, F, Mpoudi, E, Bourgeois, A, Vergne, L, ...

The genetic subtype was identified in gag and env of 219 HIV-1-positive samples collected in different African countries, 44 from Senegal, 55 from Cameroon, 82 from Gabon, and 38 from Djibouti. In...

Identification of all HIV type 1 group M subtypes in Senegal, a country with low and stable seroprevalence (2000)

Toure-Kane, C, Montavon, C, Faye, M A, Gueye, P M, Sow, P S, Ndoye, I, ...

A total of 343 HIV-1-positive samples obtained between June 1996 and March 1999 was genetically characterized in the envelope region by HMA and/or sequencing. The env subtype distribution was as...

Diagnostic approach to IBD (2000)

Peeters, M

Inflammatory bowel disease, with Crohn's disease and ulcerative colitis as the two main disorders, is a heterogeneous group of disorders of unknown etiology. Clinical initial presentation is...

Tumour necrosis factor (TNF) gene polymorphism in Crohn's disease (CD): influence on disease behaviour? (2000)

Louis, E, Peeters, M, Franchimont, D, Seidel, L, Fontaine, F, Demolin, G, ...

Crohn's disease (CD) is a multifactorial disease with genetic heterogeneity. TNF-alpha plays a key role in the development of the mucosal lesions. The aim of our work was to study a single base pair...

Morphology of homogeneous copolymers of ethylene and 1-octene. III. Structural changes during heating as revealed by time-resolved SAXS and WAXD (2000)

Goderis, Bart; U0005897, Peeters, M, Mathot, Vincent; U0009163, Koch, MHJ, Bras, W, Ryan, AJ, ...

The structural changes of two linear polyethylenes, LPEs, with different molar mass and of two homogeneous copolymers of ethylene and 1-octene with comparable comonomer content but different molar...

Near-full-length genome sequencing of divergent African HIV type 1 subtype F viruses leads to the identification of a new HIV type 1 subtype designated K (2000)

Triques, K, Bourgeois, A, Vidal, N, Mpoudi-Ngole, E, Mulanga-Kabeya, C, Nzilambi, N, ...

We recently reported a high divergence among African subtype F strains. Three well-separated groups (F1, F2, and F3) have been shown based on the phylogenetic analysis of the p24 gag and envelope...

Histopathologic validation of lymph node staging with FDG-PET scan in cancer of the esophagus and gastroesophageal junction/ A prospective study based on primary surgery with extensive lymphadenectomy (2000)

Flamen, P, Peeters, M, ...

OBJECTIVE: To assess the value of positron emission tomography with 18fluorodeoxyglucose (FDG-PET) for preoperative lymph node staging of patients with primary cancer of the esophagus and...

Equalization for DMT-based broadband modems (2000)

Peeters, M, Vandendorpe, L

Faced with fierce competition from cable operators, telephone companies are now aggressively investing in digital subscriber line technology with the objective of providing an economic broadband...

Unprecedented degree of human immunodeficiency virus type 1 (HIV-1) group M genetic diversity in the Democratic Republic of Congo suggests that the HIV-1 pandemic originated in Central Africa (2000)

Vidal, N, Peeters, M, Mulanga-Kabeya, C, Nzilambi, N, Robertson, D, Ilunga, W, ...

The purpose of this study was to document the genetic diversity of human immunodeficiency virus type 1 (HIV-1) in the Democratic Republic of Congo (DRC; formerly Zaire). A total of 247 HIV-l-positive...

Mitigation of radio interference in xDSL transmission (2000)

De Clercq, L, Peeters, M, Schelstraete, S, Pollet, T

The twisted pair copper access network was originally intended as a transmission medium for low-bandwidth analog voice signals. Unlike voiceband modems that operate in this frequency band, emerging...

Simple amplitude and phase measuring technique for ultrahigh-repetition-rate lasers (2000)

Kockaert, P, Peeters, M, Coen, S, Emplit, P, Haelterman, M, Deparis, O

A simple method for the full amplitude and phase characterization of the light emitted by continuous-wave ultrahigh-repetition-rate lasers is experimentally demonstrated. The method is based on the...

Validation of the lactose-[13C]ureide breath test for determination of orocecal transit time by scintigraphy (1999)

Geypens, Benny; U0001694, Bennink, R, Peeters, M, Maes, B, ...

The breath test using oral administration of a 13C-labeled substrate, lactose-ureide (LU), to measure orocecal transit time (OCTT) was validated against 99mTc-scintigraphy. Although LU is not...

The medical treatment of colorectal cancer: actual status and new developments (1999)

Van Cutsem, Eric; U0003840, Peeters, M, Verslype, C, Filez, Ludo; U0018865, Haustermans, Karin; U0009135, Janssens, J

Colorectal cancer is one of the most frequent malignancies and one of the greatest causes of cancer death in the Western world. The prognosis is determined by the stage at diagnosis. Patients with...

Effect of glutamine on the intestinal permeability changes induced by indomethacin in humans (1999)

Peeters, M

BACKGROUND: Long-term non-steroidal anti-inflammatory drug (NSAID) intake may induce increased intestinal permeability, eventually resulting in enteropathy. Because increased permeability might be...

Developments in fluoropyrimidine therapy for gastrointestinal cancer (1999)

Van Cutsem, Eric; U0003840, Peeters, M

The combination of 5-fluorouracil and leucovorin is the standard treatment in metastatic colorectal cancer and in Dukes' C colon cancer. There is, however, no agreement on the method for...

High diversity of HIV-1 subtype F strains in Central Africa (1999)

Triques, K, Bourgeois, A, Saragosti, S, Vidal, N, Mpoudi-Ngole, E, Nzilambi, N, ...

In this paper, we studied the variability of HIV-1 subtype F strains in Africa. For 11 viruses, mainly of Central African origin, different parts of the genome were genetically characterized. For all...

Antecedents and consequences of work-home interference among medical residents (1999)

Geurts, S, Rutte, C, Peeters, M

A cross-sectional field study is reported in which a comprehensive model of work-home interference (WHI) was developed and tested among 166 medical residents of an academic hospital in the...

Effect of long-term oral glutamine supplements on small intestinal permeability in patients with Crohn's disease (1999)

Peeters, M

Background: Glutamine is a major fuel and an important nitrogen source for the small intestinal cell. It plays a key role in maintaining mucosal cell integrity and gut barrier function. Increased...

Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes (1999)

Gao, F, Bailes, E, Robertson, D L, Chen, Ying; U0032708, Rodenburg, C M, Michael, S F, ...

The human AIDS viruses human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) represent cross-species (zoonotic) infections. Although the primate reservoir of HIV-2 has been clearly...

Evidence for differences in MT2 cell tropism according to genetic subtypes of HIV-1: syncytium-inducing variants seem rare among subtype C HIV-1 viruses (1999)

Peeters, M, Vincent, R, Perret, J L, Lasky, M, Patrel, D, Liegeois, F, ...

Non-syncytium-inducing (NSI) variants seem to be more readily transmitted than syncytium-inducing (SI) variants, and the switch from NSI to SI during HIV-1 infection seems to be a key determinant to...

Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis (1999)

Baert, F J, D'Haens, G R, Peeters, M, Hiele, Martin; U0011266, Schaible, T F, Shealy, D, ...

BACKGROUND & AIMS: Anti-tumor necrosis factor alpha monoclonal antibody treatment (infliximab) reduces clinical signs and symptoms in patients with Crohn's disease. The effects of infliximab on...

Morphology of homogeneous copolymers of ethylene and 1-octene. II. Structural changes on annealing (1999)

Peeters, M, Goderis, Bart; U0005897, Reynaers, Harry; U0005300, Mathot, Vincent; U0009163

Based on DSC evidence, annealing of ethylene-1-octene copolymers results in a gradually increasing thermal stability of the original, metastable, crystals. SAXS and WAXD were used to monitor the...

Molecular genotyping of Staphylococcus aureus strains: comparison of repetitive element sequence-based PCR with various typing methods and isolation of a novel epidemicity marker (1999)

Verbakel, H, Van Zon, J C, Frenay, I, Van Belkum, A, Peeters, M, ...

Repetitive sequence-based (Rep)-PCR genotyping as described here is based on the presence of homologues of Mycoplasma pneumoniae repeat-like elements in Staphylococcus. In this study we comparatively...

Efficiencies of four versions of the AMPLICOR HIV-1 MONITOR test for quantification of different subtypes of human immunodeficiency virus type 1 (1999)

Triques, K, Coste, J, Perret, J L, Segarra, C, Mpoudi, E, Reynes, J, ...

Three versions of a commercial human immunodeficiency virus (HIV) type 1 (HIV-1) load test (the AMPLICOR HIV-1 MONITOR Test versions 1. 0, 1.0+, and 1.5; Roche Diagnostics, Branchburg, N.J.) were...

Therapy for early-stage colorectal cancer (1999)

Peeters, M, Haller, DG

Surgery is the only curative option for patients with colorectal cancer, The goal of other modalities, such as chemotherapy, immunotherapy, and radiotherapy, is to prolong survival and reduce the...

Data transparent reconfigurable optical interconnections using polarization switching in VCSEL's induced by optical injection (1999)

Panajotov, K, Berghmans, F, Peeters, M, Verschaffelt, G, Danckaert, J, Veretennicoff, I, ...

We demonstrate a data transparent reconfigurable optical interconnection system based on optical injection controlled polarization switching in a master-slave vertical-cavity surface-emitting laser...

Characterization of a highly replicative intergroup M/O human immunodeficiency virus type 1 recombinant isolated from a Cameroonian patient (1999)

Peeters, M, Liegeois, F, Torimiro, N, Bourgeois, A, Mpoudi, E, Vergne, L, ...

A Cameroonian patient with antibodies reacting simultaneously to human immunodeficiency virus type 1 (HIV-1) group O- and group M-specific V3-loop peptides was identified. In order to confirm that...

Evaluation of small-bowel transit for solid and liquid test meal in healthy men and women (1999)

Bennink, R, Peeters, M, Geypens, Benny; U0001694, Rutgeerts, Paul; U0007636, De Roo, Michel; U0010768, ...

Evaluation of severe functional gastrointestinal motility disorders requires an investigation of the entire gastrointestinal tract. This should be possible with a single radionuclide imaging study....

Measuring monetary conditions in Europe: Use and limitations of the MCI (1999)

Peeters, M

The Monetary Conditions Index is a composite index of interest and exchange rates frequently used by (central) banks, the IMF and the OECD. This paper considers the benefits and weaknesses of the MCI...

Effect of photon-energy-dependent loss and gain mechanisms on polarization switching in vertical-cavity surface-emitting lasers (1999)

Ryvkin, B, Panajotov, K, Georgievski, A, Danckaert, J, Peeters, M, Verschaffelt, G, ...

We have analyzed the effect of the photon energy and temperature dependence of both the gain and the total losses inside the cavity to understand the polarization behavior of vertical-cavity...

The public-private savings mirror and causality relations among private savings, investment, and (twin) deficits: A full modeling approach (1999)

Peeters, M

Relations between national public and private savings, domestic investment, and the current account are analyzed with the Global Econometric Model (National Institute, London). Simulation results...

Intrapatient variability of HIV type 1 group O ANT70 during a 10-Year follow-up (1999)

Janssens, W, Nkengasong, J, Heyndrickx, L, Vereecken, Karen; U0002243, Coppens, S, ...

HIV-1 ANT70 is the first HIV-1 group O virus isolate obtained from a 25-year-old Cameroonian woman, who seroconverted in March 1987, This individual has remained asymptomatic and clinically healthy...

Synchronization with DMT modulation (1999)

Pollet, T, Peeters, M

In a digital transmission system, synchronization is an essential receiver function. Accurate timing information must be known to the demodulator in order to produce reliable estimates of the...

Comparison of total and compartmental gastric emptying and antral motility between healthy men and women (1998)

Bennink, R, Peeters, M, Geypens, Benny; U0001694, Rutgeerts, Paul; U0007636, De Roo, Michel; U0010768, ...

There is increasing evidence of gender-related differences in gastric emptying. The purpose of this study was first, to confirm the difference in gastric emptying for both solid and liquid test meals...

An isolate of human immunodeficiency virus type 1 originally classified as subtype I represents a complex mosaic comprising three different group M subtypes (A, G, and I) (1998)

Gao, F, Robertson, D L, Carruthers, C D, Li, Y, Bailes, E, Kostrikis, L G, ...

Full-length reference clones and sequences are currently available for eight human immunodeficiency virus type 1 (HIV-1) group M subtypes (A through H), but none have been reported for subtypes I and...

Comparison of the QUANTIPLEX HIV-1 RNA 2.0 assay with the AMPLICOR HIV-1 MONITOR 1.0 assay for quantitation of levels of human immunodeficiency virus type 1 RNA in plasma of patients receiving stavudine-didanosine combination therapy (1998)

Segondy, M, Izopet, J, Pellegrin, I, Montes, B, Dumon, B, Pasquier, C, ...

We compared the QUANTIPLEX HIV-1 RNA 2.0 assay with the AMPLICOR HIV-1 MONITOR 1.0 assay for quantitation of human immunodeficiency virus type 1 (HIV-1) RNA in plasma in the Stadi trail, which...

In vivo butyrate metabolism and colonic permeability in extensive ulcerative colitis (1998)

Hiele, Martin; U0011266, Peeters, M, Ghoos, Yvo; U0005088, Rutgeerts, Paul; U0007636

BACKGROUND & AIMS: Impaired short-chain fatty acid metabolism by the colonocyte has been suggested as a pathogenic factor in ulcerative colitis (UC). The aim of this study was to measure in vivo...

The 1998 national Belgian consensus meeting on HP-related diseases: an extensive summary. The HP Belgian contact group organized in CHU Brugmann, Brussels (1998)

Burete, A, Debongnie, J C, Lamy, V, ...

"HP testing must be regarded as ONE of the important elements of the proper diagnostic work-up of a DISEASE, managed in close cooperation between GP's and specialists": that's the key message of the...

Prospective evaluation of a flow chart using a risk assessment for the diagnosis of STDs in primary healthcare centres in Libreville, Gabon (1998)

Bourgeois, A, Henzel, D, Dibanga, G, Malonga-Mouelet, G, Peeters, M, Coulaud, J P, ...

BACKGROUND: The serious impact of STDs on women and children in particular, and the linkage between STDs and HIV infection are a profound concern to public health worldwide. One of the main...

Anticipation in familial Crohn's disease (1998)

Peeters, M, Franchimont, D, Gower-Rousseau, C, Speckel, D, ...

BACKGROUND: Offspring with a family history of Crohn's disease have an earlier age of onset than their parents. This might be due to genetic anticipation, characterised by earlier and/or more severe...

Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum (1998)

D'Haens, G R, Geboes, K, Peeters, M, Baert, Frank; U0004588, Penninckx, Freddy; U0018132, Rutgeerts, Paul; U0007636

BACKGROUND & AIMS: Postoperative recurrence of Crohn's disease may be triggered by agents in the fecal stream. The aim of this study was to examine intestinal mucosal inflammation induced by contact...

Breath tests in Helicobacter pylori infection: methodological aspects (1998)

Peeters, M, Ghoos, Yvo; U0005088, Geypens, Benny; U0001694, Rutgeerts, Paul; U0007636

The urea breath test (*C-UBT) is generally considered as a simple, non-invasive and accurate test to demonstrate Helicobacter pylori (Hp) infection. Sensitivity and specificity vary between 95-100%....

Clinical algorithms for the screening of pregnant women for STDs in Libreville, Gabon: which alternatives? (1998)

Bourgeois, A, Henzel, D, Malonga-Mouelet, G, Dibanga, G, Tsobou, C, Peeters, M, ...

OBJECTIVE: Sexually transmitted diseases (STDs) remain one of the major public health problems in the developing world. To implement a systematic screening of STDs among pregnant women in Libreville,...

Evidence of stable HIV seroprevalences in selected populations in the Democratic Republic of the Congo (1998)

Mulanga-Kabeya, C, Nzilambi, N, Edidi, B, Minlangu, M, Tshimpaka, T, Kambembo, L, ...

Objective: To determine current data on HIV infection and to document changes and trends of HIV seroprevalence in selected populations over time in the Democratic Republic of the Congo (DRC; former...

Irinotecan as single agent in the treatment of colorectal cancer: results of phase II studies (1998)

Peeters, M

Irinotecan of CPT11 is a topoisomerase I inhibitor The European and American regimens of irinotecan in monotherapy are different: respectively 350 mg/m(2) IV every 3 week and 125 mg/m(2) IV weekly (4...

Internal finance and corporate investment: Belgian evidence with panel data (1998)

Barran, F, Peeters, M

In this paper the corporate investment decision under financial restrictions is investigated with Belgian firm data from 1984 to 1992. An investment Euler equation is derived from a dynamic...

Polarization switching in VCSEL's due to thermal lensing (1998)

Panajotov, K, Ryvkin, B, Danckaert, J, Peeters, M, Thienpont, H, Veretennicoff, I

We demonstrate a new mechanism for polarization switching in slightly anisotropic vertical-cavity surface-emitting lasers (VCSEL's) based on index guiding due to the effect of thermal lensing, This...

Persistence, asymmetries and interrelation in factor demand (1998)

Peeters, M

A neoclassical factor demand model for structures, equipment and labour is analyzed in this paper. It incorporates a variety of dynamic specifications, such as a multi-period time-to-build for...

Fatigue during repeated eccentric-concentric and pure concentric muscle actions of the plantar flexors (1998)

Svantesson, U, Osterberg, U, Thomee, R, Peeters, M, Grimby, G

Objective. To compare the fatigue development during pure concentric actions with eccentric-concentric actions in standardized isokinetic, open-chain conditions.

GDP-spillovers in multi-country models (1998)

Douven, R, Peeters, M

Spillovers resulting from fiscal and monetary policy are compared and analysed in small static, small dynamic and large dynamic multi-country models. To compare the size of the spillovers, we...

Prevalence of the human immunodeficiency virus among patients with tuberculosis in Sierra Leone, established from dried blood spots on filter paper (1997)

Boillot, F, Peeters, M, Kosia, A, Delaporte, E

SETTING: Sierra Leone National Tuberculosis Programme. OBJECTIVE: To evaluate serological testing in field conditions of dried blood spots (DBS) on filter paper for unlinked surveillance of human...

Patchy cecal inflammation associated with distal ulcerative colitis: a prospective endoscopic study (1997)

D'Haens, G, Geboes, K, Peeters, M, Baert, Frank; U0004588, Ectors, Nadine; U0016969, Rutgeerts, Paul; U0007636

OBJECTIVES: It is generally believed that the mucosal inflammation in ulcerative colitis is characterized by a diffuse, continuous involvement starting from the rectum without "skip areas." It was...

Influence of dietary protein supplements on the formation of bacterial metabolites in the colon (1997)

Geypens, Benny; U0001694, Claus, D, Hiele, Martin; U0011266, Maes, B, Peeters, M, ...

BACKGROUND: To evaluate the influence of increased dietary protein intake on bacterial colonic metabolism in healthy volunteers. METHODS: Short chain fatty acids, ammonia, and volatile organic...

Helicobacter pylori infection and growth delay in older children (1997)

Perri, F, Pastore, M, Leandro, G, Clemente, R, Ghoos, Yvo; U0005088, Peeters, M, ...

It is thought that Helicobacter pylori infection may influence growth rate in children. The aim of this study was to evaluate the prevalence of H pylori infection in healthy Italian children, and to...

Short-term ventilatory effects in workers exposed to fumes containing zinc oxide: comparison of forced oscillation technique with spirometry (1997)

Pasker, H G, Peeters, M, Genet, P, Clément, J, Nemery, Ben; U0014190, Van De Woestijne, K P

Following the occurrence of metal fume fever in some subjects after the installation of an electric furnace in a steel plant, a survey was undertaken to examine whether subjects exposed to fumes...

Morphology of homogeneous copolymers of ethene and 1-octene .1. Influence of thermal history on morphology (1997)

Peeters, M, Goderis, Bart; U0005897, Vonk, C, Reynaers, Harry; U0005300, Mathot, Vincent; U0009163

The morphology of homogeneous copolymers of ethene and 1-octene synthesized using a V-based Ziegler-Natta catalyst was studied as a function of the short chain branching content( SCBC) and the molar...

Geographical distribution of HIV-1 group O viruses in Africa (1997)

Peeters, M, Gueye, A, Mboup, S, BibolletRuche, F, Ekaza, E, Mulanga, C, ...

Objective: To determine to what extent HIV-1 group O strains are present in different African countries.

Presence of multiple non-B subtypes and divergent subtype B strains of HIV-1 in individuals infected after overseas deployment (1997)

Lasky, M, Perrett, JL, Peeters, M, BibolletRuche, F, Liegeois, F, Patrel, D, ...

Objective: To identify the genetic subtypes and characteristics of HIV-1 strains from individuals infected after overseas deployment.

Virology of HIV-1 and HIV-2: implications for Africa (1997)

Peeters, M, Guéye-Ndiaye, A

Harvard AIDS Institute, Boston, Massachusetts 02115, USA.

Refractive index dispersion of sodium magnesium silicate glasses for ultralow-loss fibers (1997)

Todoroki, S, Sakaguchi, S, Peeters, M

The refractive index dispersion and infrared (IR) reflection spectra of soda magnesium silicate glasses with low Rayleigh scattering mere measured to evaluate their potential for use in fabricating...

Dynamics of the population structure of Bordetella pertussis as measured by IS1002-associated RFLP: comparison of pre- and post-vaccination strains and global distribution (1996)

Vernooij, S, Peeters, M, Van Embden, J, Mooi, F R

The effect of temporal and geographic factors on the population structure of Bordetella pertussis was studied using IS1002-based RFLP analysis. Among the 106 strains analysed, 36 different RFLP types...

A clinical validation of Bordetella pertussis and Bordetella parapertussis polymerase chain reaction: comparison with culture and serology using samples from patients with suspected whooping cough from a highly immunized population (1996)

Agterberg, C, Peeters, M, Mooi, F, Schellekens, J

The aim of this study was to validate the performance of the polymerase chain reaction (PCR) assay for Bordetella pertussis and Bordetella parapertussis in comparison with both culture and serology....

Virological and immunological analysis of a triple combination pilot study with loviride, lamivudine and zidovudine in HIV-1-infected patients (1996)

Miller, V, Rehmet, S, Stark, T, De Crée, J, De Brabander, M, ...

OBJECTIVE: To compare two antiretroviral regiments, loviride plus lamivudine (3TC) plus zidovudine (ZDV) (triple combination) and loviride plus ZDV (double combination) in terms of pharmacokinetic...

Comparative evaluation of three assays for the quantitation of human immunodeficiency virus type 1 RNA in plasma (1996)

Coste, J, Montes, B, Reynes, J, Peeters, M, Segarra, C, Vendrell, JP, ...

Reverse transcriptase-coupled polymerase chain reaction (Amplicor HIV-1 Monitor), the branched DNA(bDNA) method (Quantiplex HIV-1 RNA)and the nucleic acid sequence-based assay (NASBA HIV-1 RNA QT)...

Investment gestation lags: The difference between time-to-build and delivery lags (1996)

Peeters, M

The timing of investment and capital stock accumulation can differ as a result of time-to-build and/or delivery lags. In this paper simple (calibration) methods are used to illustrate the differences...

The coffin-siris-syndrome - data on mental-development, language, behavior and social skills in 12 children (1995)

Swillen, Ann; U0040725, Glorieux, N, Peeters, M

In this report we present data on cognitive development, language, behavior and social skills in 12 children and adolescents, nine girls and three boys, aged between 2.5 and 19 years, with...

Equal IgG antibody response to pneumococcal vaccination in all stages of human immunodeficiency virus disease (1995)

Vandenbruaene, M, Colebunders, R, Mascart-Lemone, F, Haerden, Y, Van Hove, D, Peeters, M, ...

To evaluate the immunogenicity and safety of a 23-valent pneumococcal vaccine in human immunodeficiency virus (HIV)-seropositive patients, 80 men and 18 women received 1 dose of the vaccine (Pneumo...

Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection (1995)

Rutgeerts, Paul; U0007636, Hiele, Martin; U0011266, Geboes, K, Peeters, M, Penninckx, Freddy; U0018132, Aerts, Raymond; U0002616, ...

BACKGROUND/AIMS: New lesions recur within weeks to months after ileal resection and ileocolonic anastomosis for Crohn's ileitis. A double-blind controlled trial was performed using metronidazole to...

Infectious virus titer, replicative and syncytium-inducing capacity of human immunodeficiency virus type 1 (1995)

Nkengasong, J N, Peeters, M, Nys, P, Willems, B, Piot, P

The relationship was investigated between a viral infectious titer in peripheral blood mononuclear cells (PBMC) and plasma on the replicative and syncytium-inducing capacity of human immunodeficiency...

A participatory ergonomics approach to reduce mental and physical workload (1995)

Vink, P, Peeters, M, Grundemann, Rwm, Smulders, Pgw, Kompier, Maj, Dul, J

A step-by-step approach to better work, aimed at reducing mental and physical workload in office work, is evaluated. This approach is based on a strong commitment of the management in the enterprise,...

Phenotypic and functional parameters of cellular-immunity in a chimpanzee with a naturally acquired simian immunodeficiency virus-infection (1995)

Kestens, L, Vingerhoets, J, Peeters, M, Vanham, G, Vereecken, C, Penne, G, ...

The cellular immunologic and virologic status of a chimpanzee, naturally infected with a human immunodeficiency virus type 1 (HIV-1)-like lentivirus (SIVcpz-ant), was compared longitudinally with...

HIV-1 group O infection in Belgium (1995)

Peeters, M, Lobe, V, Nkengasong, J, Willems, B, Delforge, M L, Van Renterghem, L, ...

Institute of Tropical Medicine, Department of Microbiology, Antwerp, Belgium.

Correlation between genetic and biological properties of biologically cloned hiv type-1 viruses representing subtype-a, subtype-b, and subtype-d (1995)

Zhong, P, Peeters, M, Janssens, W, Fransen, K, Heyndrickx, L, Vanham, G, ...

The relationship between the genetic variability in the V3 loop and the biological characteristics of 38 biological clones from 5 European and 7 African HIV-1 isolates belonging to 3 different...

Virus load in chimpanzees infected with human-immunodeficiency-virus type-1 - effect of preexposure vaccination (1995)

Tenhaaft, P, Cornelissen, M, Goudsmit, J, Koornstra, W, Dubbes, R, Niphuis, H, ...

Many reports indicate that a long-term asymptomatic state following human immunodeficiency virus type I (HIV-1) infection is associated with a low amount of circulating virus. To evaluate the...

Biological phenotypes of hiv-1 subtype-a and subtype-b strains of diverse origins (1995)

Nkengasong, Jn, Peeters, M, Zhong, P, Willems, B, Janssens, W, Heyndrickx, L, ...

The identification of specific biologic phenotypic traits that can be correlated with different HIV-1 genetic subtypes was sought. The genetic subtypes were determined by either sequencing...

Increased permeability of macroscopically normal small bowel in Crohn's disease (1994)

Peeters, M, Ghoos, Yvo; U0005088, Maes, B, Hiele, Martin; U0011266, Geboes, K, Vantrappen, Gaston; U0017164, ...

To investigate permeability alterations of the macroscopically normal jejunum in Crohn's disease, the permeation of two probes was measured during perfusion of an isolated jejunal segment. The data...

Cross-neutralizing antibodies to hiv-1(ant70) and hiv-1(iiib) in sera of african and belgian hiv-1-infected individuals (1994)

Nkengasong, Jn, Peeters, M, Ndumbe, P, Janssens, W, Willems, B, Fransen, K, ...

Objectives: To determine the neutralizing antibody patterns to HIV-1(ANT70) (ANT70) and HIV-1(IIIB)(IIIB) in human sera obtained from HIV-1-infected individuals from different African countries and...

Demographic factors associated with HTLV-1 infection in a Gabonese community (1994)

Delaporte, E, Gaudebout, C, Trebuck, A, Schrijvers, D, Josse, R, ...

An epidemiological study of human T-lymphotropic virus type 1 (HTLV-1) and syphilis has been carried out in a multiethnic community of seven neighbouring villages located in eastern Gabon on 1240...

Quantification of human immunodeficiency virus in plasma by RNA PCR, viral culture, and p24 antigen detection (1994)

Fransen, K, Peeters, M, De Beenhouwer, H, Piot, P

A semiquantitative PCR technique for detecting human immunodeficiency virus type 1 (HIV-1) RNA in plasma was compared with quantitative viral culture and p24 antigen detection in plasma. Ninety-three...

Effect of methodology on detection of HIV-1/HIV-2 dual infections in Côte d'Ivoire (1994)

Peeters, M, Fransen, K, Gershy-Damet, G M, Willems, B, Koffi, K, Coulibaly, M, ...

Dual seroreactivity to the human immunodeficiency virus (HIV) types 1 and 2 is common in Côte d'Ivoire. To assess whether dual infection is the reason for dual seroreactivity, different methods for...

Crystallization phenomena in bacterial poly[(r)-3-hydroxybutyrate] .3. toughening via texture changes (1994)

Scheeren, Ahc, Lemstra, Pj, Peeters, M

Poly[(R)-3-hydroxybutyrate] (PHB) is a bacterial storage polyester that is genuinely biodegradable, but its brittleness hampers its wide applicability as a biodegradable plastic. Most attempts to...

Genetic and antigenic variability of hiv type-1 in brazil (1994)

Janssens, W, Heyndrickx, L, Motte, J, Fransen, K, Peeters, M, ...

Six Brazilian strains of human immunodeficiency virus type 1 (HIV-1) were isolated from infected individuals residing in different regions of Brazil between 1987 and 1989. Phylogenetic analysis based...

Design and evaluation of new, highly sensitive and specific primers for polymerase chain-reaction detection of hiv-1-infected primary lymphocytes (1994)

Zhong, P, Debeenhouwer, H, Carpels, G, Peeters, M, Louwagie, J, ...

Primer pairs in the HIV-1 POL and ENV genes were evaluated by performing a PCR on lysed peripheral blood mononuclear cells (PBMCs) from 96 HIV-1 seropositive and 40 seronegative individuals...

Polymerase chain reaction assay for pertussis: simultaneous detection and discrimination of Bordetella pertussis and Bordetella parapertussis (1993)

Agterberg, C, Peeters, M, Schellekens, J, Mooi, F R

A polymerase chain reaction (PCR) assay which allows the simultaneous detection and discrimination of the two causative agents of pertussis, Bordetella pertussis and Bordetella parapertussis, was...

Phylogenetic analysis of gag genes from 70 international HIV-1 isolates provides evidence for multiple genotypes (1993)

McCutchan, F E, Peeters, M, Brennan, T P, Sanders-Buell, E, Eddy, G A, ...

OBJECTIVE: To determine the extent of genetic variation among internationally collected HIV-1 isolates, to analyse phylogenetic relationships and the geographic distribution of different variants....

Metabolism of thiamine triphosphate in rat brain: correlation with chloride permeability (1993)

Peeters, M, Wins, P, Schoffeniels, E

Our results show that a net synthesis of thiamine triphosphate (TTP) can be demonstrated in vitro using rat brain extracts. The total homogenate was preincubated with thiamine or its diphosphate...

Non-Hodgkin lymphoma in Gabon and its relation to HTLV-I (1993)

Klotz, F, Peeters, M, Martin-Prevel, Y, Bedjabaga, L, Larouzé, B, ...

A case-control study was performed in Libreville, Gabon, to determine whether a relationship can be established between the relatively high proportion of non-Hodgkin lymphoma (NHL) among all cancer...

Characterization of IS1001, an insertion sequence element of Bordetella parapertussis (1993)

Agterberg, C, Van Agterveld, M, Peeters, M, Mooi, F R

By analysis of repetitive DNA in Bordetella parapertussis, an insertion sequence element, designated IS1001, was identified. Sequence analysis revealed that IS1001 comprised 1,306 bp and contained...

Hiv-infection in european female sex workers - epidemiologic link with use of petroleum-based lubricants (1993)

Peeters, M, Laga, M, Piot, P, Vandenhoek, A, Vanderhelm, T, ...

Objectives: To assess the prevalence of and risk factors associated with HIV infection in European female sex workers, particularly sexual risk factors.

Infectious agents in inflammatory bowel disease (1992)

Peeters, M

Department of Medicine and Pathology, University Hospital Gasthuisberg, Leuven, Belgium.

Rifabutin and ethambutol do not help recurrent Crohn's disease in the neoterminal ileum (1992)

Van Isveldt, J, Peeters, M, ...

We tested the efficacy of rifabutin and ethambutol in combination in healing severe recurrent Crohn's disease in the neoterminal ileum. Sixteen patients who had undergone an ileal resection with...

Amino-acids and 21-trisomy (1992)

Rethore, Mo, Deblois, Mc, Peeters, M, Naffah, J, Megarbane, A, ...

The relative concentrations of plasmatic and urinary aminoacids were analysed in 79 trisomic-21 patients, 322 mentally retarded non-trisomic patients, and 206 controls. No true aminoacidopathy was...

Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum (1991)

Peeters, M, ...

Aphthous lesions recur in the neoterminal ileum within the first few months after curative resection of the distal ileum in patients with Crohn's disease. These lesions do not originate from...

Evaluation of a line immunoassay for simultaneous confirmation of antibodies to HIV-1 and HIV-2 (1991)

Pollet, D E, Peeters, M, Van Kerckhoven, I, Beelaert, G, Vercauteren, G, ...

An anti-HIV-1/HIV-2 line immunoassay (LIA), using peptides and recombinant antigens was evaluated against commercially available Western blot tests for HIV-1 and HIV-2 antibodies. Two thousand one...

Human T-cell lymphotropic virus type I infection and pregnancy: a case-control study and 12-month follow-up of 135 women and their infants (1991)

Delaporte, E, Peeters, M, Leruez, M, Glowaczower, E, Fernandez, H

Human T-cell lymphotropic virus type I (HTLV-I) infection is common in Gabon, but its influence on pregnancy is unknown. A single case of acute T-cell leukemia in a pregnant woman has been reported...

Prevalence of HTLV-I and HTLV-II infection in Gabon, Africa: comparison of the serological and PCR results (1991)

Monplaisir, N, Louwagie, J, Peeters, M, Martin-Prével, Y, Louis, J P, ...

A cluster sampling survey was performed in 1989 in Libreville, Gabon, to determine HTLV-I and HTLV-II prevalence and to compare the efficacy of polymerase chain reaction (PCR) and serology in...

Determination of thiamin and its phosphate esters in cultured neurons and astrocytes using an ion-pair reversed-phase high-performance liquid chromatographic method (1991)

Peeters, M, Jouan, C, Wins, P, Schoffeniels, E

A sensitive method, based on fluorescence detection, for the determination of thiamin derivatives after precolumn derivatization is described. The separation is achieved on a PRP-1 column using...

Pure partial trisomy of the short arm of chromosome 5 (1989)

Blois, M C, Peeters, M, Popowski, P, Pangalos, C, Lejeune, J

We describe a male infant with multiple dysmorphic features who is trisomic for chromosome segment 5p13.32----5p14.2 as a result of recombination aneusomy. His father is a balanced carrier of an...

[Infantile psychosis, pseudo-Alzheimer syndrome, and trisomy 21. A trial of treatment with folinic acid: preliminary report] (1989)

Rethoré, M O, De Blois, M C, Peeters, M

Trisomy 21 produces excess sensibility to methotrexate (dihydrofolate reductase inhibitor). A trial of medication with folinic acid (5-formyl-tetrahydrofolate) was realized on 39 trisomic 21...

Epidemiology of HTLV-I in Gabon (Western Equatorial Africa) (1988)

Dupont, A, Peeters, M, Josse, R, Merlin, M, Schrijvers, D, ...

In 1986 a survey to determine the distribution of HTLV-I infection was conducted in Gabon in a representative sample of adults and children. Five samples were taken in adults and 2 samples in...

Curing of endogenous 2 micron DNA in yeast by recombinant vectors (1987)

Peeters, M

Passaging on selective media of yeast strains transformed with complete 2 micron vectors carrying TRP1, LEU2 or URA3 selective markers leads to curing of the resident endogenous 2 micron DNA in a...

Megakaryoblastic leukemia and Down's syndrome: a review (1987)

Peeters, M, Poon, A

Megakaryoblastic leukemia and transient leukemia in Down's syndrome have been reviewed using case reports from the literature and our own experience at the Hospital for Sick Children. The following...

Biotypes of Gardnerella vaginalis (1984)

Van Dyck, E, Peeters, M, Hale, J, Totten, P A, Holmes, K K

A simple and reproducible scheme for identifying biotypes of Gardnerella vaginalis has been developed, based on reactions for lipase, hippurate hydrolysis, and beta-galactosidase. Among a total of...