Tiwari-Pandey, Rashmi, Yang, Yinzhi, Aravindakshan, Jayaprakash, Sairam, M.Ram
Genetically modified follitrophin receptor knockout female mice with total FSH-receptor (FSH-R) deletion are sterile and their combined estrogen deficiency-hyperandrogenemic status provides an...
Tiwari-Pandey, Rashmi, Yang, Yinzhi, Aravindakshan, Jayaprakash, Sairam, M.Ram
Genetically modified follitrophin receptor knockout female mice with total FSH-receptor (FSH-R) deletion are sterile and their combined estrogen deficiency-hyperandrogenemic status provides an...
Tiwari-Pandey, Rashmi, Yang, Yinzhi, Aravindakshan, Jayaprakash, Sairam, M.Ram
Genetically modified follitrophin receptor knockout female mice with total FSH-receptor (FSH-R) deletion are sterile and their combined estrogen deficiency-hyperandrogenemic status provides an...
Chen, Xinlei, Aravindakshan, Jayaprakash, Yang, Yinzhi, Tiwari-Pandey, Rashmi, Sairam, M.Ram
Although PDGF family members play a vital role in cell proliferation, motility and chemotaxis via activation of structurally similar α- and β-receptors, little is known of their function in ovarian...
Chen, Xinlei, Aravindakshan, Jayaprakash, Yang, Yinzhi, Pandey, Rashmi Tiwari, Sairam, M. Ram
Although PDGF family members play a vital role in cell proliferation, motility, and chemotaxis via activation of structurally similar α- and β-receptors, little is known of their function in...
Amit Grover, M. Ram Sairam, Charles E. Smith, Louis Hermo
Follicle stimulating hormone (FSH) plays important roles during testicular development and in the maintenance of spermatogenesis in the adult. However, the cellular events or pathways that FSH...
Agneta Balla, Natalia Danilovich, Yinzhi Yang, M. Ram Sairam
Adult Follitropin Receptor Knockout (FORKO) female mice are infertile and estrogen deficient. In order to understand the peri/postnatal developmental changes, we have now characterized the structural...
Yinzhi Yang, Agneta Balla, Natalia Danilovich, M. Ram Sairam
Targeted disruption of the mouse FSH receptor gene (FSH-R) that mediates the action of the FSH results in a gene dose-related ovarian phenotype in the developing as well as the adult animal. While...
Dierich, Andrée, Sairam, M. Ram, Monaco, Lucia, Fimia, Gian Maria, Gansmuller, Anne, LeMeur, Marianne, ...
Pituitary gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone stimulate the gonads by regulating germ cell proliferation and differentiation. FSH receptors (FSH-Rs) are localized...
Dierich, Andrée, Sairam, M. Ram, Monaco, Lucia, Fimia, Gian Maria, Gansmuller, Anne, LeMeur, Marianne, ...
Pituitary gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone stimulate the gonads by regulating germ cell proliferation and differentiation. FSH receptors (FSH-Rs) are localized...
Aravindakshan, Jayaprakash, Chen, Xinlei, Sairam, M Ram
Ovarian cancer is a deadly disease with long latency. To understand the consequences of loss of folliclestimulating hormone receptor (FSH-R) signaling and to explore why the atrophic and anovulatory...
Chen, Xinlei, Aravindakshan, Jayaprakash, Yang, Yinzhi, Sairam, M. Ram
Little is known about the behavior of the ovarian surface epithelium (OSE), which plays a central role in ovarian cancer etiology. It has been suggested that incessant ovulation causes OSE changes...