M. Roberge

Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. That inhibit amoeboid invasion by human tutor cells. (2005)

Williams, D.E., Austin, P., Diaz-Marrero, A.R., Soest, R.W.M. Van, Soest, R.W.M. Van, Matainaho, T., ...

Dominicin, a cyclic Octapeptide, and Laughine, a bromopyrrole Alkaloid, isolated from the Caribbean Marine Sponge Eurypon laughlini. (2005)

Williams, D.E., O.Patrick, B., Behrisch, H.W., Soest, R.W.M. Van, Soest, R.W.M. Van, Roberge, M., ...

Trisphaerolide A, a novel polyketide from the Dominican sponge Erylus trisphaerus (2003)

Altena, I. Van, Soest, R.W.M. Van, Roberge, M., Andersen, R.J.

New okadaic acid analogues from the marine sponge phorbas oxeota and their effect on mitosis (2003)

Britton, R., Roberge, M., Brown, C., Soest, R.W.M. Van, Andersen, R.J.

Motuporamines, anti-invasion and anti-angiogenic alkaloids from the marine sponge Xestospongia exigua (Kirkpatrick): isolation, structure elucidation, analogue synthesis, and conformational analysis (2002)

Williams, D.E., Craig, K.S., Patrick, B., McHardy, L.M., Soest, R.W.M. Van, Roberge, M., ...

Nucleosome positioning as a critical determinant for the DNA cleavage sites of mammalian DNA topoisomerase II in reconstituted simian virus 40 chromatin.

Capranico, G, Jaxel, C, Roberge, M, Kohn, K W, Pommier, Y

We have assessed the ability of nucleosomes to influence the formation of mammalian topoisomerase II-DNA complexes by mapping the sites of cleavage induced by four unrelated topoisomerase II...

Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B (II)-dependent transcription in vitro.

Verdier, J M, Stalder, R, Roberge, M, Amati, B, Sentenac, A, Gasser, S M

We present a reproducible method for the preparation of nuclear extracts from the yeast Saccharomyces cerevisiae that support efficient RNA polymerase B (II)-dependent transcription. Extracts from...

Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation.

Guo, X W, Th'ng, J P, Swank, R A, Anderson, H J, Tudan, C, Bradbury, E M, ...

Chromosome condensation at mitosis correlates with the activation of p34cdc2 kinase, the hyperphosphorylation of histone H1 and the phosphorylation of histone H3. Chromosome condensation can also be...

Identification of two acidic residues involved in the catalysis of xylanase A from Streptomyces lividans.

Moreau, A, Roberge, M, Manin, C, Shareck, F, Kluepfel, D, Morosoli, R

On the basis of similarities between known xylanase sequences of the F family, three invariant acidic residues of xylanase A from Streptomyces lividans were investigated. Site-directed-mutagenesis...

The head activator is released from regenerating Hydra bound to a carrier molecule

Schaller, H. C., Roberge, M., Zachmann, B., Hoffmeister, S., Schilling, E., Bodenmüller, H.

Hydra forced to regenerate a head releases head activator and head inhibitor during the first hours after cutting to induce head-specific growth and differentiation processes. Analysis of the size...

Substrate-binding domains of glycanases from Streptomyces lividans: characterization of a new family of xylan-binding domains.

Dupont, C, Roberge, M, Shareck, F, Morosoli, R, Kluepfel, D

The substrate-binding domains of six glycanases from Streptomyces lividans were investigated to determine their specificity towards cellulose and xylan. Based upon amino acid sequence similarities,...

Nucleosome positioning as a critical determinant for the DNA cleavage sites of mammalian DNA topoisomerase II in reconstituted simian virus 40 chromatin.

Capranico, G, Jaxel, C, Roberge, M, Kohn, K W, Pommier, Y

We have assessed the ability of nucleosomes to influence the formation of mammalian topoisomerase II-DNA complexes by mapping the sites of cleavage induced by four unrelated topoisomerase II...

Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B (II)-dependent transcription in vitro.

Verdier, J M, Stalder, R, Roberge, M, Amati, B, Sentenac, A, Gasser, S M

We present a reproducible method for the preparation of nuclear extracts from the yeast Saccharomyces cerevisiae that support efficient RNA polymerase B (II)-dependent transcription. Extracts from...

Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation.

Guo, X W, Th'ng, J P, Swank, R A, Anderson, H J, Tudan, C, Bradbury, E M, ...

Chromosome condensation at mitosis correlates with the activation of p34cdc2 kinase, the hyperphosphorylation of histone H1 and the phosphorylation of histone H3. Chromosome condensation can also be...

Identification of two acidic residues involved in the catalysis of xylanase A from Streptomyces lividans.

Moreau, A, Roberge, M, Manin, C, Shareck, F, Kluepfel, D, Morosoli, R

On the basis of similarities between known xylanase sequences of the F family, three invariant acidic residues of xylanase A from Streptomyces lividans were investigated. Site-directed-mutagenesis...

The head activator is released from regenerating Hydra bound to a carrier molecule

Schaller, H. C., Roberge, M., Zachmann, B., Hoffmeister, S., Schilling, E., Bodenmüller, H.

Hydra forced to regenerate a head releases head activator and head inhibitor during the first hours after cutting to induce head-specific growth and differentiation processes. Analysis of the size...

Substrate-binding domains of glycanases from Streptomyces lividans: characterization of a new family of xylan-binding domains.

Dupont, C, Roberge, M, Shareck, F, Morosoli, R, Kluepfel, D

The substrate-binding domains of six glycanases from Streptomyces lividans were investigated to determine their specificity towards cellulose and xylan. Based upon amino acid sequence similarities,...