Ankylosing spondylitis and bowel disease (2006)
Between 5 and 10% of cases of ankylosing spondylitis (AS) are associated with inflammatory bowel disease (IBD), either Crohn's disease or ulcerative colitis. A much larger percentage of AS patients...
Baraliakos, X, Listing, J, Brandt, J, Rudwaleit, M, Sieper, J, Braun, J
No abstract available.
Baraliakos, X, Listing, J, Rudwaleit, M, Brandt, J, Sieper, J, Braun, J
No abstract available.
Häupl, T, Grützkau, A, Grün, J, Krenn, V, Rudwaleit, M, Stuhlmüller, B, ...
No abstract available.
Monocyte-specific gene signatures in rheumatoid arthritis (2004)
Grützkau, A, Grün, J, Rudwaleit, M, Goldschmidt, L, Burmester, G-R, Radbruch, A, ...
No abstract available.
Häupl, T, Grützkau, A, Grün, J, Baumgrass, R, Janitz, M, Stuhlmüller, B, ...
No abstract available.
Sieper, J, Rudwaleit, M, Braun, J, VAN DER HEIJDE, Desiree
Free Univ Berlin, Klinikum Benjamin Franklin, D-12200 Berlin, Germany. German Rheumatol Res Ctr, Berlin, Germany. Univ Hosp Maastricht, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek,...
Sieper, J, Rudwaleit, M, Braun, J, VAN DER HEIJDE, Desiree
Free Univ Berlin, Klinikum Benjamin Franklin, D-12200 Berlin, Germany. German Rheumatol Res Ctr, Berlin, Germany. Univ Hosp Maastricht, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek,...
HLA class II antigens associated with systemic lupus erythematosus in black South Africans.
Rudwaleit, M, Tikly, M, Gibson, K, Pile, K, Wordsworth, P
OBJECTIVE--To assess the associations of HLA class II antigens with systemic lupus erythematosus (SLE) in black South Africans. METHODS--HLA-DRB1 genotype frequencies assigned by polymerase chain...
Rudwaleit, M., Yin, Z., Siegert, S., Grolms, M., Radbruch, A., Braun, J., ...
OBJECTIVE—This study was performed to assess whether there is any change in the T cell cytokine pattern in early rheumatoid arthritis (RA) patients treated with methotrexate (MTX) and whether the...
Rudwaleit, M, Siegert, S, Yin, Z, Eick, J, Thiel, A, Radbruch, A, ...
OBJECTIVE—To test the hypothesis that ankylosing spondylitis (AS) is a T helper cell type 2 polarised disease by quantifying the T cell cytokines interferon γ (IFNγ), interleukin 4 (IL4),...
Low incidence of reactive arthritis in children following a salmonella outbreak
Rudwaleit, M, Richter, S, Braun, J, Sieper, J
OBJECTIVES—To assess the incidence of reactive arthritis (ReA) in an outbreak of salmonella infection in a large cohort of children in Germany. METHODS—A few days after the salmonella outbreak...
Atopic disorders in ankylosing spondylitis and rheumatoid arthritis
Rudwaleit, M, Andermann, B, Alten, R, Sorensen, H, Listing, J, Zink, A, ...
Background: The prevalence of atopic disorders in ankylosing spondylitis (AS) is unknown. AS and rheumatoid arthritis (RA) exhibit divergent T helper (Th) cell cytokine patterns.
Zou, J, Rudwaleit, M, Brandt, J, Thiel, A, Braun, J, Sieper, J
Objective: To assess the change in the cytokine secreting ability of CD4+ and CD8+ T cells and macrophages during etanercept treatment.
Braun, J., Xiang, J., Brandt, J., Maetzel, H., Haibel, H., Wu, P., ...
Ankylosing spondylitis: an overview
Sieper, J, Braun, J, Rudwaleit, M, Boonen, A, Zink, A
Ankylosing spondylitis (AS) is a complex, potentially debilitating disease that is insidious in onset, progressing to radiological sacroiliitis over several years. Patients with symptomatic AS lose...
How to diagnose axial spondyloarthritis early
Rudwaleit, M, Khan, M, Braun, J, Sieper, J
Background: Chronic low back pain (LBP), the leading symptom of ankylosing spondylitis (AS) and undifferentiated axial spondyloarthritis (SpA), precedes the development of radiographic sacroiliitis,...
Rudwaleit, M, Listing, J, Brandt, J, Braun, J, Sieper, J
Background: TNFα blockers have been shown to be highly efficacious in patients with active ankylosing spondylitis (AS).
Braun, J, Baraliakos, X, Golder, W, Hermann, K, Listing, J, Brandt, J, ...
Objectives: To compare conventional radiography and magnetic resonance imaging (MRI) for detection of chronic changes in the spine of patients with ankylosing spondylitis (AS).
Brandt, J, Listing, J, Sieper, J, Rudwaleit, M, Braun, J
Objective: To develop and compare candidate improvement criteria for anti-TNFα treatment in ankylosing spondylitis with optimal discriminating capacity between treatment and placebo.
Listing, J, Brandt, J, Rudwaleit, M, Zink, A, Sieper, J, Braun, J
Methods: The data of a 2 year open extension study of a 12 week, double blind, randomised, placebo controlled trial, in which all patients with AS were treated with 5 mg/kg infliximab, were used to...
Six months open label trial of leflunomide in active ankylosing spondylitis
Haibel, H, Rudwaleit, M, Braun, J, Sieper, J
Patients and methods: Twenty patients with AS fulfilling the 1984 modified New York criteria with a Bath AS Disease Activity Index (BASDAI) >3 were given leflunomide for 6 months. Clinical outcome...
Open label trial of anakinra in active ankylosing spondylitis over 24 weeks
Haibel, H, Rudwaleit, M, Listing, J, Sieper, J
Methods: Anakinra (100 mg) was given subcutaneously daily over 24 weeks to 20 NSAID refractory patients with ankylosing spondylitis. Thirteen completed the study. Clinical outcome assessments...
Baraliakos, X, Landewe, R, Hermann, K, Listing, J, Golder, W, Brandt, J, ...
Background: Magnetic resonance imaging (MRI) is increasingly used to detect inflammation in the spine of patients with ankylosing spondylitis (AS).
Analysis of the CD8+ T cell response to the G1 domain of aggrecan in ankylosing spondylitis
Zou, J, Appel, H, Rudwaleit, M, Thiel, A, Sieper, J
Background: CD4+ T cell responses to the G1 domain of aggrecan in patients with ankylosing spondylitis (AS) were recently reported. Whether such an immune response can be seen in the CD8+...
Baraliakos, X, Hermann, K, Landewe, R, Listing, J, Golder, W, Brandt, J, ...
Objectives: To compare the performance of two different MRI sequences—T1 weighted, fat saturated, spin echo after application of contrast medium, and short τ inversion recovery (STIR)...