M. Shimada

Publication List Details

Period

1974 - 2008

Number

155

Co-Authors

INSTITUTE OF PHYSICS PUBLISHING PHYSICS IN MEDICINE AND BIOLOGY (2008)

M Shimada, Y Yamada, T Yatagai

Melanin and blood concentration in a human skin model studied by multiple regression analysis:

M. de S. G. Tsuzuki and (2008)

M. Shimada, Escola Politécnica, Sistemas Mecânicos

The expansion of the application domain of geometric modeling in more and more engineering fields is making the robust implementations of the underlying geometric computations very essential....

Optimization of a Seeded Free-Electron Laser with Helical Undulators (2008)

Labat, M., Hosaka, M., Shimada, M., Katoh, M., Couprie, M. E.

Seeded single pass free-electron lasers are promising coherent, short-duration, and intense light sources, from the visible to x rays. Operated with adjustable undulators, they are also a unique...

Presented at the 5th International (2007)

T. Tamayama, M. Shimada, M. Watanabe

Histologic distribution of insulin and glucagon receptors Department of Anatomy, Osaka Medical College,

A comparison of postoperative hypoesthesia between two types of sagittal split ramus osteotomy and intraoral vertical ramus osteotomy, using the trigeminal somatosensory-evoked potential method (2007)

Takazakura, Daisuke, Ueki, Koichiro, Nakagawa, Kiyomasa, Marukawa, Kohei, Shimada, M., Shamiula, A., ...

The purpose of this study was to evaluate hypoesthesia of the lower lip using trigeminal somatosensory-evoked potential following 2 types of sagittal split ramus osteotomy (SSRO) and intraoral...

Chapter 3: MHD stability, operational limits and disruptions (2007)

Hender, T. C., Wesley, J. C., Bialek, J., Bondeson, A., Boozer, A. H., Buttery, R. J., ...

Progress in the area of MHD stability and disruptions, since the publication of the 1999 ITER Physics Basis document (1999 Nucl. Fusion 39 2137-2664), is reviewed. Recent theoretical and experimental...

Chapter 8: Plasma operation and control (2007)

Gribov, Y., Humphreys, D., Kajiwara, K., Lazarus, E. A., Lister, J. B., Ozeki, T., ...

The ITER plasma control system has the same functional scope as the control systems in present tokamaks. These are plasma operation scenario sequencing, plasma basic control (magnetic and kinetic),...

Edge localized modes control: experiment and theory (2005)

Becoulet, M., Huysmans, G., Thomas, P., Joffrin, E., Rimini, F., Monier-Garbet, P., ...

The paper reviews recent theoretical and experimental results focussing on the identification of the key factors controlling ELM energy and particle losses both in natural ELMs and in the presence of...

Use of the Airborne Visible/Infrared Imaging Spectrometer to Calibrate the Optical Sensor on Board the Japanese Earth Resources Satellite-1 (2004)

Green, R., Conel, J., Van Den Bosch, Jeneatte, Shimada, M.

In this paper, we describe an experiment to calibrate the Optical Sensor on board the Japanese Earth Resources Satellite-1 with data acquired by the Airborne Visible/Infrared Imaging Spectrometer...

On-Orbit Calibration of a Multi-Spectral Satellite Satellite Sensor Using a High Altitude Airborne Imaging Spectrometer (2004)

Green, R. O., Shimada, M.

Earth-looking satellites must be calibrated in order to quantitatively measure and monitor components of land, water and atmosphere of the Earth system. The inevitable change in performance due to...

Data Quality of the JERS-1 SAR Global Rain Forest Mapping (GRFM) Project (2004)

Chapman, B., Alves, M., Shimada, M., Freeman, T., Rosenqvist, A., Siqueira, P.

The National Space Development Agency of Japan's (NASDA) JERS-1 SAR began collecting data in 1995 for the Global Rain Forest Mapping Project (GRFM). The GRFM data quality has been examined for...

On-Orbit Calibration of ADEOS OCTS with AVIRIS Underflight (2004)

Green, R., Pavri, B., Boardman, J., Shimada, M., Oaku, H.

An analogous satellite underflight calibration experiment was performed with AVIRIS and the Optical Sensor (OPS) onboard the Japanese Earth Resources Satellite (JERS).

Geometric classification tests using interval arithmetic in b-rep solid modeling (2003)

Shimada,M.

In this work, the use of interval arithmetic is considered to increase robustness of geometric classification algorithms in B-Rep solid modeling systems. The classification algorithms, also known as...

ELM energy and particle losses and their extrapolation to burning plasma experiments (2003)

Loarte,A., Saibene,G., Sartori,R., Becoulet,M., Horton,L., Eich,T., ...

Analysis of Type I ELMs from present experiments shows that ELM energy losses decrease with increasing pedestal plasma collisionality (ν*ped) and/or increasing τFront║, where...

Characteristics of type I ELM energy and particle losses in existing devices and their extrapolation to ITER (2003)

Loarte,A., Saibene,G., Sartori,R., Campbell,D., Becoulet,M., Horton,L., ...

Analysis of Type I ELMs from ongoing experiments shows that ELM energy losses are correlated with the density and temperature of the pedestal plasma before the ELM crash. The Type I ELM plasma energy...

Key ITER plasma edge and plasma–material interaction issues (2003)

Federici,G., Andrew,P., Barabashi,P., Brooks,J., Doerner,R., Geier,A., ...

Some of the remaining crucial plasma edge physics and plasma–material interaction issues of the ITER tokamak are discussed in this paper, using either modelling or projections of experimental...

Comparison of ITER performance predicted by semi-empirical and theory-based transport models (2003)

Mukhovatov,V., Shimomura,Y., Polevoi,A., Shimada,M., Sugihara,M., Bateman,G., ...

The values of Q = (fusion power)/(auxiliary heating power) predicted for ITER by three different methods are compared. The first method utilizes an empirical confinement-time scaling and prescribed...

Overview of physics basis for ITER (2003)

Mukhovatov,V., Shimada,M., Chudnovskiy,A. N., Costley,A. E., Gribov,Y., Federici,G., ...

ITER will be the first magnetic confinement device with burning DT plasma and fusion power of about 0.5 GW. Parameters of ITER plasma have been predicted using methodologies summarized in the ITER...

ELM energy and particle losses and their extrapolation to burning plasma experiments (2003)

Loarte, A., Saibene, G., Sartori, R., Becoulet, M., Horton, L., Eich, T., ...

Analysis of Type I ELMs from present experiments shows that ELM energy losses decrease with increasing pedestal plasma collisionality (ν*ped) and/or increasing τFront║, where...

Characteristics of type I ELM energy and particle losses in existing devices and their extrapolation to ITER (2003)

Loarte, A., Saibene, G., Sartori, R., Campbell, D., Becoulet, M., Horton, L., ...

Analysis of Type I ELMs from ongoing experiments shows that ELM energy losses are correlated with the density and temperature of the pedestal plasma before the ELM crash. The Type I ELM plasma energy...

Key ITER plasma edge and plasma–material interaction issues (2003)

Federici, G., Andrew, P., Barabashi, P., Brooks, J., Doerner, R., Geier, A., ...

Some of the remaining crucial plasma edge physics and plasma–material interaction issues of the ITER tokamak are discussed in this paper, using either modelling or projections of experimental...

Comparison of ITER performance predicted by semi-empirical and theory-based transport models (2003)

Mukhovatov, V., Shimomura, Y., Polevoi, A., Shimada, M., Sugihara, M., Bateman, G., ...

The values of Q = (fusion power)/(auxiliary heating power) predicted for ITER by three different methods are compared. The first method utilizes an empirical confinement-time scaling and prescribed...

Overview of physics basis for ITER (2003)

Mukhovatov, V., Shimada, M., Chudnovskiy, A. N., Costley, A. E., Gribov, Y., Federici, G., ...

ITER will be the first magnetic confinement device with burning DT plasma and fusion power of about 0.5 GW. Parameters of ITER plasma have been predicted using methodologies summarized in the ITER...

Vertebrate TBP-like protein (TLP/TRF2/TLF) stimulates TATA-less terminal deoxynucleotidyl transferase promoters in a transient reporter assay, and TFIIA-binding capacity of TLP is required for this function (2003)

Ohbayashi, T., Shimada, M., Nakadai, T., Wada, T., Handa, H., Tamura, T.

The TBP‐like protein (TLP/TRF2/TLF), which belongs to the TBP family of proteins, is present in all metazoan organisms. Although the human TLP has been reported to interfere with transcription...

Key ITER plasma edge and plasma-material interaction issues. (2003)

Federici, G., Andrew, P., Barabaschi, P., Brooks, J., Doerner, R., Geier, A., ...

Proc. of the 15th Internat.Conf.on Plasma Surface Interactions in Controlled Fusion Devices (PSI-15), Gifu, J, May 27-31, 2002

ELM energy and particle losses and their extrapolation to burning plasma experiments. (2003)

Loarte, A., Saibene, G., Sartori, R., Becoulet, M., Horton, L., Eich, T., ...

Proc. of the 15th Internat.Conf.on Plasma Surface Interactions in Controlled Fusion Devices (PSI-15), Gifu, J, May 27-31, 2002

Deep Optical Imaging of A Compact Group of Galaxies, Seyfert's Sextet (2000)

Nishiura, S., Murayama, T., Shimada, M., Sato, Y., Nagao, T., Molikawa, K., ...

In order to investigate the dynamical status of Seyfert's Sextet (SS), we have obtained a deep optical ($VR+I$) image of this group. Our image shows that a faint envelope, down to a surface...

A Dynamical Study of Galaxies in the Hickson Compact Groups (2000)

Nishiura, S., Shimada, M., Ohyama, Y., Murayama, T., Taniguchi, Y.

In order to investigate dynamical properties of spiral galaxies in the Hickson compact groups (HCGs), we present rotation curves of 30 galaxies in 20 HCGs. We found as follows. 1) There is not...

Warm Precracking at 295 K and Its Effects on the 4-K Toughness of Austenitic Steels. (1998)

Tobler, R.L., Shimada, M.

The effect of warm precracking at room temperature or liquid nitrogen temperature on the toughness at 4 K has been investigated in Fe-17Cr-3Ni-13Mn-0.33N and Fe-13Cr-5Ni-22Mn-0.21N steels. In the...

Grain-Size Dependence of Thermal-Shock Resistance of Yttria-Doped Tetragonal Zirconia Polycrystals. (1998)

Ishitsuka, M., Sato, T., Endo, T., Shimada, M., Ohno, H.

Thermal-shock fracture behavior of yttria-doped tetragonal zirconia polycrystals (Y-TZP) of various grain sizes was evaluated by the quenching method using water as the quenching solvent. The...

Hydrothermal Corrosion of Magnesia-Partially-Stabilized Zirconia. (1998)

Sato, T., Endo, T., Shimada, M., Mitsudome, T., Otabe, N.

Changes in the phase composition and microstructures of magnesia-partially-stabilized zirconia (Mg-PSZ) were studied in water at 80-300C, 1M HCl solutions at 80-140C and 1M CH3COOH-CH3COONa buffer...

High Temperature Corrosion and Degradation in Strength of Silicon Nitride Based Ceramics by Alkali Sulfates and Carbonates Melts. (1998)

Shimada, M., Sato, T., Endo, T.

Si3N4 based ceramics such as hot isostatically pressed Si3N4, hot pressed Si3N4, hot pressed sialons containing 0, 30, 60 and 100% of alpha phase were corrodeed by K2SO4 and K2CO3 melts at 1150-1300...

Corrosion of Silicon Nitride Ceramics Under Hydrothermal Conditions. (1998)

Sato, T., Murakami, T., Endo, T., Shimada, M., Komeya, K.

Corrosion behavior of Si3N4 ceramics containing Y2O3, Al2O3 and AlN as sintering aids was investigated under hydrothermal conditions at 200-300 C and saturated vapor pressures of water for 1-10 days....

Histologic distribution of insulin and glucagon receptors (1998)

Watanabe,M., Hayasaki,H., Tamayama,T., Shimada,M.

Insulin and glucagon are the hormonal polypeptides secreted by the B and A cells of the endocrine pancreas, respectively. Their major physiologic effects are regulation of carbohydrate metabolism,...

Strategies for Reducing Blood Transfusions in Hepatic Resection (1994)

T. Matsumata, H. Itasaka, K. Shirabe, M. Shimada, K. Yanaga, K. Sugimachi

A comparison of 60 blood transfused and 71 nonblood transfused hepatic resection patients was done to evaluate strategies for reducing blood transfusions during hepatic surgery. There were no...

SINTERING AND FRACTURE BEHAVIOR OF COMPOSITES BASED ON ALUMINA-ZIRCONIA (YTTRIA)-NONOXIDES (1986)

Sato, T., Shiratori, A., Shimada, M.

Strength and toughness of Al2O3 based ceramics were improved by dispersing ZrO2 (Y2O3) and nonoxide materials such as SiC, TiC, TiN and B4C. Significant toughening and hardening were attained in...

SINTERING AND FRACTURE BEHAVIOR OF COMPOSITES BASED ON ALUMINA-ZIRCONIA (YTTRIA)-NONOXIDES (1986)

Sato, T., Shiratori, A., Shimada, M.

Strength and toughness of Al2O3 based ceramics were improved by dispersing ZrO2 (Y2O3) and nonoxide materials such as SiC, TiC, TiN and B4C. Significant toughening and hardening were attained in...

SINTERING AND FRACTURE BEHAVIOR OF COMPOSITES BASED ON ALUMINA-ZIRCONIA (YTTRIA)-NONOXIDES (1986)

Sato, T., Shiratori, A., Shimada, M.

Strength and toughness of Al2O3 based ceramics were improved by dispersing ZrO2 (Y2O3) and nonoxide materials such as SiC, TiC, TiN and B4C. Significant toughening and hardening were attained in...

INTERNAL FRICTION AND MECHANICAL PROPERTIES OF NEW CERAMICS (1985)

Matsushita, K., Okamoto, T., Shimada, M.

Stress amplitude and temperature dependences of internal friction in polycrystal and single crystal aluminas and aluminas subjected to thermal shock, were measured. Microcracks introduced by water...

INTERNAL FRICTION IN PARTIALLY STABILIZED ZIRCONIA (1985)

Matsushita, K., Okamoto, T., Shimada, M.

Internal friction was measured by the flexural vibration method at 1-6 KHz. Internal friction peaks in partially stabilized zirconia with Y2O3 or Nd2O3 are observed at about 200 °C. The intensity of...

INTERNAL FRICTION AND MECHANICAL PROPERTIES OF NEW CERAMICS (1985)

Matsushita, K., Okamoto, T., Shimada, M.

Stress amplitude and temperature dependences of internal friction in polycrystal and single crystal aluminas and aluminas subjected to thermal shock, were measured. Microcracks introduced by water...

INTERNAL FRICTION IN PARTIALLY STABILIZED ZIRCONIA (1985)

Matsushita, K., Okamoto, T., Shimada, M.

Internal friction was measured by the flexural vibration method at 1-6 KHz. Internal friction peaks in partially stabilized zirconia with Y2O3 or Nd2O3 are observed at about 200 °C. The intensity of...

INTERNAL FRICTION AND MECHANICAL PROPERTIES OF NEW CERAMICS (1985)

Matsushita, K., Okamoto, T., Shimada, M.

Stress amplitude and temperature dependences of internal friction in polycrystal and single crystal aluminas and aluminas subjected to thermal shock, were measured. Microcracks introduced by water...

INTERNAL FRICTION IN PARTIALLY STABILIZED ZIRCONIA (1985)

Matsushita, K., Okamoto, T., Shimada, M.

Internal friction was measured by the flexural vibration method at 1-6 KHz. Internal friction peaks in partially stabilized zirconia with Y2O3 or Nd2O3 are observed at about 200 °C. The intensity of...

DISLOCATION MOTION IN VA METALS STUDIED BY INTERNAL FRICTION (1981)

Okuda, S., Mizubayashi, H., Kuramochi, N., Amano, S., Shimada, M., Tatekawa, H.

Dislocation motion in Va metals, V, Nb and Ta at low temperatures was studied by internal friction and dynamic modulus measurements. The results on pure and impure Nb and Ta support the assignment...

INTERNAL FRICTION OF DEFORMED IRON CONTAINING HYDROGEN (1981)

Sakamoto, K., Shimada, M.

Internal friction of the deformed and hydrogen doped α-Fe shows three peaks near 130K, 170K and 330K at 1 Hz. The 130K and 170K peaks are hydrogen cold work peaks and the 330K peak is a...

DISLOCATION MOTION IN VA METALS STUDIED BY INTERNAL FRICTION (1981)

Okuda, S., Mizubayashi, H., Kuramochi, N., Amano, S., Shimada, M., Tatekawa, H.

Dislocation motion in Va metals, V, Nb and Ta at low temperatures was studied by internal friction and dynamic modulus measurements. The results on pure and impure Nb and Ta support the assignment...

INTERNAL FRICTION OF DEFORMED IRON CONTAINING HYDROGEN (1981)

Sakamoto, K., Shimada, M.

Internal friction of the deformed and hydrogen doped α-Fe shows three peaks near 130K, 170K and 330K at 1 Hz. The 130K and 170K peaks are hydrogen cold work peaks and the 330K peak is a...

DISLOCATION MOTION IN VA METALS STUDIED BY INTERNAL FRICTION (1981)

Okuda, S., Mizubayashi, H., Kuramochi, N., Amano, S., Shimada, M., Tatekawa, H.

Dislocation motion in Va metals, V, Nb and Ta at low temperatures was studied by internal friction and dynamic modulus measurements. The results on pure and impure Nb and Ta support the assignment...

INTERNAL FRICTION OF DEFORMED IRON CONTAINING HYDROGEN (1981)

Sakamoto, K., Shimada, M.

Internal friction of the deformed and hydrogen doped α-Fe shows three peaks near 130K, 170K and 330K at 1 Hz. The 130K and 170K peaks are hydrogen cold work peaks and the 330K peak is a...

MÖSSBAUER EFFECT OF SrLnFeO4 (Ln=La, Pr, Nd) (1979)

Shimada, M., Koizumi, M., Takano, M., Shinjo, T., Takada, T.

The Mössbauer effect has been studied in SrLaFeO4, SrPrFeO4, and SrNdFeO4, with K2NiF4 structure in the temperature range between 4 K and 640 K. The results of the combined magnetic and quadrupole...

MÖSSBAUER EFFECT OF SrLnFeO4 (Ln=La, Pr, Nd) (1979)

Shimada, M., Koizumi, M., Takano, M., Shinjo, T., Takada, T.

The Mössbauer effect has been studied in SrLaFeO4, SrPrFeO4, and SrNdFeO4, with K2NiF4 structure in the temperature range between 4 K and 640 K. The results of the combined magnetic and quadrupole...

MÖSSBAUER EFFECT OF SrLnFeO4 (Ln=La, Pr, Nd) (1979)

Shimada, M., Koizumi, M., Takano, M., Shinjo, T., Takada, T.

The Mössbauer effect has been studied in SrLaFeO4, SrPrFeO4, and SrNdFeO4, with K2NiF4 structure in the temperature range between 4 K and 640 K. The results of the combined magnetic and quadrupole...

SUPERTRANSFERRED HYPERFINE FIELD AT Sn4+ IN (Ca1-x Srx) MnO3 AND (Ca1-x Srx)2MnO4 (1974)

Takano, M., Takeda, Y., Shimada, M., Matsuzawa, T.

We prepared (Ca1-xSrx)Mn0.99119Sn0.01O3 with the cubic perovskite structure and (Ca1-xSrx)2Mn0.99119Sn0.01O4 with the tetragonal K2NiF4 type structure (0 ⩽ x ⩽ 1 in both cases) and...

SUPERTRANSFERRED HYPERFINE FIELD AT Sn4+ IN (Ca1-x Srx) MnO3 AND (Ca1-x Srx)2MnO4 (1974)

Takano, M., Takeda, Y., Shimada, M., Matsuzawa, T.

We prepared (Ca1-xSrx)Mn0.99119Sn0.01O3 with the cubic perovskite structure and (Ca1-xSrx)2Mn0.99119Sn0.01O4 with the tetragonal K2NiF4 type structure (0 ⩽ x ⩽ 1 in both cases) and...

SUPERTRANSFERRED HYPERFINE FIELD AT Sn4+ IN (Ca1-x Srx) MnO3 AND (Ca1-x Srx)2MnO4 (1974)

Takano, M., Takeda, Y., Shimada, M., Matsuzawa, T.

We prepared (Ca1-xSrx)Mn0.99119Sn0.01O3 with the cubic perovskite structure and (Ca1-xSrx)2Mn0.99119Sn0.01O4 with the tetragonal K2NiF4 type structure (0 ⩽ x ⩽ 1 in both cases) and...

Suppression of diet-induced atherosclerosis in low density lipoprotein receptor knockout mice overexpressing lipoprotein lipase.

Shimada, M, Ishibashi, S, Inaba, T, Yagyu, H, Harada, K, Osuga, J I, ...

Lipoprotein lipase (LPL) is a key enzyme in the hydrolysis of triglyceride-rich lipoproteins. Conflicting results have been reported concerning its role in atherogenesis. To determine the effects of...

Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia.

Shimano, H, Yamada, N, Katsuki, M, Shimada, M, Gotoda, T, Harada, K, ...

Apolipoprotein E (apoE) has a high affinity to cell-surface low density lipoprotein (LDL) receptor. To determine the role of apoE in plasma lipoprotein metabolism, transgenic mouse lines with...

Analysis of the chicken TBP-like protein(tlp) gene: evidence for a striking conservation of vertebrate TLPs and for a close relationship between vertebrate tbp and tlp genes.

Shimada, M, Ohbayashi, T, Ishida, M, Nakadai, T, Makino, Y, Aoki, T, ...

TLP (TBP-like protein), which is a new protein dis-covered by us, has a structure similar to that of the C-terminal conserved domain (CCD) of TBP, although its function has not yet been elucidated....

Vertebrate TBP-like protein (TLP/TRF2/TLF) stimulates TATA-less terminal deoxynucleotidyl transferase promoters in a transient reporter assay, and TFIIA-binding capacity of TLP is required for this function

Ohbayashi, T., Shimada, M., Nakadai, T., Wada, T., Handa, H., Tamura, T.

The TBP-like protein (TLP/TRF2/TLF), which belongs to the TBP family of proteins, is present in all metazoan organisms. Although the human TLP has been reported to interfere with transcription from...

The role of ribonuclease H in multicopy single-stranded DNA synthesis in retron-Ec73 and retron-Ec107 of Escherichia coli.

Shimamoto, T, Shimada, M, Inouye, M, Inouye, S

Bacterial reverse transcriptase is responsible for the synthesis of multicopy single-stranded DNA (msDNA). Reverse transcriptases from retron-Ec73 and retron-Ec107 do not contain an RNase H domain....

Detection of alcohol-tolerant hiochi bacteria by PCR.

Nakagawa, T, Shimada, M, Mukai, H, Asada, K, Kato, I, Fujino, K, ...

We report a sensitive and rapid method for detection of hiochi bacteria by PCR. This method involves the electrophoresis of amplified DNA. Nucleotide sequences of the spacer region between 16S and...

Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice.

Shimano, H, Namba, Y, Ohsuga, J, Kawamura, M, Yamamoto, K, Shimada, M, ...

To investigate the role of apoE in hepatic uptake of chylomicron remnants, we studied chylomicron metabolism in transgenic mice overexpressing apoE in the liver. Plasma clearance of injected...

Macrophage colony-stimulating factor regulates both activities of neutral and acidic cholesteryl ester hydrolases in human monocyte-derived macrophages.

Inaba, T, Shimano, H, Gotoda, T, Harada, K, Shimada, M, Kawamura, M, ...

Macrophage colony-stimulating factor (M-CSF) regulates cholesterol metabolism in vivo and in vitro. We studied the effects of M-CSF on enzyme activities of acidic cholesteryl ester (CE) hydrolase,...

Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall.

Shimano, H, Ohsuga, J, Shimada, M, Namba, Y, Gotoda, T, Harada, K, ...

Apolipoprotein E (apoE) plays a crucial role in lipoprotein metabolism both in plasma and in peripheral tissues. To test whether apoE in the vascular wall has a direct and local effect on...

Apolipoprotein E prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits.

Yamada, N, Inoue, I, Kawamura, M, Harada, K, Watanabe, Y, Shimano, H, ...

Apo E plays an important role in plasma lipoprotein metabolism through its high affinity binding to cell surface LDL receptor. In the present study, we studied the effects of apo E on the atherogenic...

Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B.

Shimano, H, Yamada, N, Katsuki, M, Yamamoto, K, Gotoda, T, Harada, K, ...

We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma cholesterol and triglyceride levels due to the disappearance of VLDL and LDL. In this study, we...

Rheumatoid arthritis and B cell lymphoma with pathological changes of reactive histiocytosis.

Shimada, M, Kojima, M, Tani, G, Komatsumoto, S, Nara, M

A 67 year old woman with rheumatoid arthritis was admitted to hospital in acute renal failure. Her clinical features included increasing dyspnoea and oedema, and a computed tomogram of the abdomen...

Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.

Abe, H, Yamada, N, Kamata, K, Kuwaki, T, Shimada, M, Osuga, J, ...

Insulin resistance is often associated with atherosclerotic diseases in subjects with obesity and impaired glucose tolerance. This study examined the effects of insulin resistance on coronary risk...

Prognostic factors after repeat hepatectomy for recurrent hepatocellular carcinoma.

Shimada, M, Takenaka, K, Taguchi, K, Fujiwara, Y, Gion, T, Kajiyama, K, ...

OBJECTIVE: The aims of this study were to identify prognostic factors in patients who developed recurrent hepatocellular carcinoma (HCC) after repeat hepatectomy and to elucidate the role of...

Assessment of cervical lymph node metastasis in esophageal carcinoma using ultrasonography.

Natsugoe, S, Yoshinaka, H, Shimada, M, Shirao, K, Nakano, S, Kusano, C, ...

OBJECTIVE: To evaluate the efficacy of ultrasonography for the diagnosis of cervical lymph node metastasis in esophageal carcinoma. SUMMARY BACKGROUND DATA: Ultrasound (US) examination is useful for...

Reversal of hypersplenism following orthotopic liver transplantation.

Yanaga, K, Tzakis, A G, Shimada, M, Campbell, W E, Marsh, J W, Stieber, A C, ...

The purpose of this study was to clarify the effect of orthotopic liver transplantation on hypersplenism. In a 1-year period from July 1, 1986 to June 30, 1987, 196 adult patients underwent 233...

Local cerebral alterations in [14C-2]deoxyglucose uptake following memory formation.

Shimada, M, Murakami, T H, Imahayashi, T, Ozaki, H S

In order to show changes in the local cerebral glucose utilization during an avoidance task, dry-autoradiography with [14C]deoxyglucose was employed in the present work. The following regions showed...

Microvessel and astroglial cell densities in the mouse hippocampus.

Shimada, M, Akagi, N, Goto, H, Watanabe, H, Nakanishi, M, Hirose, Y, ...

In order to study the factors responsible for glucose uptake in the mouse hippocampus, microvessel and astroglial cell densities were measured and compared in each laminal region. Microvessel density...

Suppression of diet-induced atherosclerosis in low density lipoprotein receptor knockout mice overexpressing lipoprotein lipase.

Shimada, M, Ishibashi, S, Inaba, T, Yagyu, H, Harada, K, Osuga, J I, ...

Lipoprotein lipase (LPL) is a key enzyme in the hydrolysis of triglyceride-rich lipoproteins. Conflicting results have been reported concerning its role in atherogenesis. To determine the effects of...

Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia.

Shimano, H, Yamada, N, Katsuki, M, Shimada, M, Gotoda, T, Harada, K, ...

Apolipoprotein E (apoE) has a high affinity to cell-surface low density lipoprotein (LDL) receptor. To determine the role of apoE in plasma lipoprotein metabolism, transgenic mouse lines with...

Analysis of the chicken TBP-like protein(tlp) gene: evidence for a striking conservation of vertebrate TLPs and for a close relationship between vertebrate tbp and tlp genes.

Shimada, M, Ohbayashi, T, Ishida, M, Nakadai, T, Makino, Y, Aoki, T, ...

TLP (TBP-like protein), which is a new protein dis-covered by us, has a structure similar to that of the C-terminal conserved domain (CCD) of TBP, although its function has not yet been elucidated....

Vertebrate TBP-like protein (TLP/TRF2/TLF) stimulates TATA-less terminal deoxynucleotidyl transferase promoters in a transient reporter assay, and TFIIA-binding capacity of TLP is required for this function

Ohbayashi, T., Shimada, M., Nakadai, T., Wada, T., Handa, H., Tamura, T.

The TBP-like protein (TLP/TRF2/TLF), which belongs to the TBP family of proteins, is present in all metazoan organisms. Although the human TLP has been reported to interfere with transcription from...

The role of ribonuclease H in multicopy single-stranded DNA synthesis in retron-Ec73 and retron-Ec107 of Escherichia coli.

Shimamoto, T, Shimada, M, Inouye, M, Inouye, S

Bacterial reverse transcriptase is responsible for the synthesis of multicopy single-stranded DNA (msDNA). Reverse transcriptases from retron-Ec73 and retron-Ec107 do not contain an RNase H domain....

Detection of alcohol-tolerant hiochi bacteria by PCR.

Nakagawa, T, Shimada, M, Mukai, H, Asada, K, Kato, I, Fujino, K, ...

We report a sensitive and rapid method for detection of hiochi bacteria by PCR. This method involves the electrophoresis of amplified DNA. Nucleotide sequences of the spacer region between 16S and...

Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice.

Shimano, H, Namba, Y, Ohsuga, J, Kawamura, M, Yamamoto, K, Shimada, M, ...

To investigate the role of apoE in hepatic uptake of chylomicron remnants, we studied chylomicron metabolism in transgenic mice overexpressing apoE in the liver. Plasma clearance of injected...

Macrophage colony-stimulating factor regulates both activities of neutral and acidic cholesteryl ester hydrolases in human monocyte-derived macrophages.

Inaba, T, Shimano, H, Gotoda, T, Harada, K, Shimada, M, Kawamura, M, ...

Macrophage colony-stimulating factor (M-CSF) regulates cholesterol metabolism in vivo and in vitro. We studied the effects of M-CSF on enzyme activities of acidic cholesteryl ester (CE) hydrolase,...

Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall.

Shimano, H, Ohsuga, J, Shimada, M, Namba, Y, Gotoda, T, Harada, K, ...

Apolipoprotein E (apoE) plays a crucial role in lipoprotein metabolism both in plasma and in peripheral tissues. To test whether apoE in the vascular wall has a direct and local effect on...

Apolipoprotein E prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits.

Yamada, N, Inoue, I, Kawamura, M, Harada, K, Watanabe, Y, Shimano, H, ...

Apo E plays an important role in plasma lipoprotein metabolism through its high affinity binding to cell surface LDL receptor. In the present study, we studied the effects of apo E on the atherogenic...

Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B.

Shimano, H, Yamada, N, Katsuki, M, Yamamoto, K, Gotoda, T, Harada, K, ...

We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma cholesterol and triglyceride levels due to the disappearance of VLDL and LDL. In this study, we...

Rheumatoid arthritis and B cell lymphoma with pathological changes of reactive histiocytosis.

Shimada, M, Kojima, M, Tani, G, Komatsumoto, S, Nara, M

A 67 year old woman with rheumatoid arthritis was admitted to hospital in acute renal failure. Her clinical features included increasing dyspnoea and oedema, and a computed tomogram of the abdomen...

Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.

Abe, H, Yamada, N, Kamata, K, Kuwaki, T, Shimada, M, Osuga, J, ...

Insulin resistance is often associated with atherosclerotic diseases in subjects with obesity and impaired glucose tolerance. This study examined the effects of insulin resistance on coronary risk...

Local cerebral alterations in [14C-2]deoxyglucose uptake following memory formation.

Shimada, M, Murakami, T H, Imahayashi, T, Ozaki, H S

In order to show changes in the local cerebral glucose utilization during an avoidance task, dry-autoradiography with [14C]deoxyglucose was employed in the present work. The following regions showed...

Prognostic factors after repeat hepatectomy for recurrent hepatocellular carcinoma.

Shimada, M, Takenaka, K, Taguchi, K, Fujiwara, Y, Gion, T, Kajiyama, K, ...

OBJECTIVE: The aims of this study were to identify prognostic factors in patients who developed recurrent hepatocellular carcinoma (HCC) after repeat hepatectomy and to elucidate the role of...

Assessment of cervical lymph node metastasis in esophageal carcinoma using ultrasonography.

Natsugoe, S, Yoshinaka, H, Shimada, M, Shirao, K, Nakano, S, Kusano, C, ...

OBJECTIVE: To evaluate the efficacy of ultrasonography for the diagnosis of cervical lymph node metastasis in esophageal carcinoma. SUMMARY BACKGROUND DATA: Ultrasound (US) examination is useful for...

Microvessel and astroglial cell densities in the mouse hippocampus.

Shimada, M, Akagi, N, Goto, H, Watanabe, H, Nakanishi, M, Hirose, Y, ...

In order to study the factors responsible for glucose uptake in the mouse hippocampus, microvessel and astroglial cell densities were measured and compared in each laminal region. Microvessel density...

Reversal of hypersplenism following orthotopic liver transplantation.

Yanaga, K, Tzakis, A G, Shimada, M, Campbell, W E, Marsh, J W, Stieber, A C, ...

The purpose of this study was to clarify the effect of orthotopic liver transplantation on hypersplenism. In a 1-year period from July 1, 1986 to June 30, 1987, 196 adult patients underwent 233...

A comparison of postoperative hypoesthesia between two types of sagittal split ramus osteotomy and intraoral vertical ramus osteotomy, using the trigeminal somatosensory-evoked potential method

Takazakura, Daisuke, Ueki, Koichiro, Nakagawa, Kiyomasa, Marukawa, Kohei, Shimada, M., Shamiula, A., ...

The purpose of this study was to evaluate hypoesthesia of the lower lip using trigeminal somatosensory-evoked potential following 2 types of sagittal split ramus osteotomy (SSRO) and intraoral...

Angiopoietin switching regulates angiogenesis and progression of human hepatocellular carcinoma

Sugimachi, K, Tanaka, S, Taguchi, K, Aishima, S, Shimada, M, Tsuneyoshi, M

Aim: Angiopoietin 1 (Ang-1) and its antagonist, angiopoietin 2 (Ang-2), are novel ligands that regulate the Tie2 receptor. The Ang-2 gene is upregulated in the hypervascular type of human...

Counter-regulatory effect of sodium butyrate on tumour necrosis factor-alpha (TNF-α)-induced complement C3 and factor B biosynthesis in human intestinal epithelial cells

Andoh, A, Fujiyama, Y, Hata, K, Araki, Y, Takaya, H, Shimada, M, ...

The various biological activities of butyrate have been well documented. In this study, we tested the effects of butyrate on TNF-α-induced complement C3 and factor B biosynthesis in human intestinal...

Cooperation of interleukin-17 and interferon-γ on chemokine secretion in human fetal intestinal epithelial cells

Andoh, A, Takaya, H, Makino, J, Sato, H, Bamba, S, Araki, Y, ...

Interleukin (IL)-17 is a newly identified T cell-derived cytokine that can regulate the functions of a variety of cell types. In this study, we investigated the effects of IL-17 and interferon...

Spastic tetraplegia as an initial manifestation of familial Alzheimer's disease.

Sodeyama, N, Shimada, M, Uchihara, T, Yanagisawa, K, Fujigasaki, H, Yamaguchi, K, ...

Two sisters with familial Alzheimer's disease developed spastic gait disturbance as an initial manifestation. Their gait disturbance progressed gradually, followed by dementia a few years later....

Effect of hydrofluoric acid on glucose metabolism of the mouse studied by whole-body autoradiography.

Watanabe, M, Yoshida, Y, Watanabe, M, Shimada, M, Kurimoto, K

Distribution of radioactive carbon from [U-14C]glucose in the mouse poisoned by hydrofluoric acid has been studied by whole-body autoradiography. Under normal conditions, the highest autoradiographic...

Decreased cortical glucose metabolism correlates with hippocampal atrophy in Alzheimer's disease as shown by MRI and PET.

Yamaguchi, S, Meguro, K, Itoh, M, Hayasaka, C, Shimada, M, Yamazaki, H, ...

OBJECTIVE: To investigate the relation between atrophy of the hippocampus and parahippocampal gyrus (the % hippocampal area) and cerebral metabolic rate for glucose (CMRGlc) in Alzheimer's disease....

Strategies for Reducing Blood Transfusions in Hepatic Resection

Matsumata, T., Itasaka, H., Shirabe, K., Shimada, M., Yanaga, K., Sugimachi, K.

A comparison of 60 blood transfused and 71 nonblood transfused hepatic resection patients was done to evaluate strategies for reducing blood transfusions during hepatic surgery. There were no...

A safe and simple technique for exchanging central venous catheters.

Shimada, M., Matsumata, T., Wakiyama, S., Maeda, T., Kanematsu, T., Sugimachi, K.

A safe and simple technique for exchanging central venous catheters is herein described. Our technique is based on a modification of Seldinger's method, in which a new outer sheath is introduced over...

Effect of Flumazenil on Disturbance of Equilibrium Function Induced by Midazolam

Maeda, S, Miyawaki, T, Higuchi, H, Shimada, M

Benzodiazepines in intravenous sedation are useful, owing to their outstanding amnesic effect when used for oral surgery as well as dental treatments on patients with intellectual disability or...

Efficacy of five annual single doses of diethylcarbamazine for treatment of lymphatic filariasis in Fiji.

Mataika, J. U., Kimura, E., Koroivueta, J., Shimada, M.

Annual single-dose treatments with diethylcarbamazine citrate (DEC) at a dose of 6 mg/kg have been reported effective in reducing microfilariae (mf) rate and density and applicable to large-scale...

Extranodal connective tissue invasion and the expression of desmosomal glycoprotein 1 in squamous cell carcinoma of the oesophagus.

Natsugoe, S., Mueller, J., Kijima, F., Aridome, K., Shimada, M., Shirao, K., ...

We investigated extranodal connective tissue involvement (ECTI) in 39 patients with oesophageal carcinoma. Both the primary tumour and ECTI were immunohistochemically examined using the monoclonal...

Telomerase activity and p53-dependent apoptosis in ovarian cancer cells

Akeshima, R, Kigawa, J, Takahashi, M, Oishi, T, Kanamori, Y, Itamochi, H, ...

We conducted the present study to determine the relationship between p53-dependent apoptosis and telomerase activity in ovarian cancer cells. A human ovarian adenocarcinoma cell line, SK-OV-3 that...