Spectral Characteristic of Metallic State of Polyacetylene. (9999)
Tanaka, J., Tanaka, C., Miyamae, T., Kamiya, K., Shimizu, M.
The absorption, reflection and ultraviolet photoemission spectra (UPS) of thin films of polyacetylene doped with perchlorate ion or potassium are studied to find the mechanism of insulator to metal...
Periodic metallo-dielectric structure in diamond (2009)
Shimizu, M, Shimotsuma, Y, Sakakura, M, Yuasa, T, Homma, H, Minowa, Y, ...
Nishizuka, N., Shimizu, M., Nakamura, T., Otsuji, K., Okamoto, T. J., Katsukawa, Y., ...
Hinode discovered a beautiful giant jet with both cool and hot components at the solar limb on 2007 February 9. Simultaneous observations by the Hinode SOT, XRT, and TRACE 195 satellites revealed...
Kaneda, M., Shimizu, M., Hayakawa, T., Nishimura, A., Iriki, Y., Tsuchida, H., ...
A new experimental technique has been developed for the investigation of secondary particle emission from liquid targets resulting from collision interactions with fast charged particles. Secondary...
Kaneda, M., Shimizu, M., Hayakawa, T., Nishimura, A., Iriki, Y., Tsuchida, H., ...
A new experimental technique has been developed for the investigation of secondary particle emission from liquid targets resulting from collision interactions with fast charged particles. Secondary...
Au-Bi-Te melts: Annealing-quenching experiments on material from the Oya gold deposit (Japan) (2007)
Ciobanu, Cristiana Liana, Mavrogenes, John, Cook, Nigel John, Shimizu, M.
http://www.gtk.fi/geotieto/julkaisut/Uusimmat/Julkaisut/Opas53.html
Au-Bi-Te melts: Annealing-quenching experiments on material from the Oya gold deposit (Japan) (2007)
Ciobanu, Cristiana Liana, Mavrogenes, John, Cook, Nigel John, Shimizu, M.
http://www.gtk.fi/geotieto/julkaisut/Uusimmat/Julkaisut/Opas53.html
Energy loss and small angle scattering of swift protons passing through liquid ethanol target (2007)
Kaneda, M., Sato, S., Shimizu, M., He, Z., Ishii, K., Tsuchida, H., ...
Shimizu, M., Kurita, Kenichi, Matsuura, H., Ishimaru, Jun-Ichi, Goss, Alastair Norman
Copyright © 2006 International Association of Oral and Maxillofacial Surgeons Published by Elsevier Ltd.
Hayakawa, A., Shimizu, M., Woli, K. P., Kuramochi, K., Hatano, R.
We evaluated the impacts of natural wetlands and various land uses on stream nitrogen concentration in two grassland-dominated catchments in eastern Hokkaido, Japan. Analyzing land use types in...
Hayakawa, A., Shimizu, M., Woli, K. P., Kuramochi, K., Hatano, R.
We evaluated the impacts of natural wetlands and various land uses on stream nitrogen concentration in two grassland-dominated catchments in eastern Hokkaido, Japan. Analyzing land use types in...
Shimizu, M., Kurita, Kenichi, Matsuura, H., Ishimaru, Jun-Ichi, Goss, Alastair Norman
Copyright © 2006 International Association of Oral and Maxillofacial Surgeons Published by Elsevier Ltd.
Hiramitsu, T., Yasuda, T., Ito, H., Shimizu, M., Julovi, S. M., Kakinuma, T., ...
Objective. In rheumatoid arthritis (RA), it is well known that rheumatoid synovial fibroblasts (RSF) produce matrix metalloproteinases (MMPs) when stimulated with proinflammatory cytokines such as...
Hiramitsu, T., Yasuda, T., Ito, H., Shimizu, M., Julovi, S. M., Kakinuma, T., ...
Objective. In rheumatoid arthritis (RA), it is well known that rheumatoid synovial fibroblasts (RSF) produce matrix metalloproteinases (MMPs) when stimulated with proinflammatory cytokines such as...
Hiramitsu, T., Yasuda, T., Ito, H., Shimizu, M., Julovi, S. M., Kakinuma, T., ...
Objective. In rheumatoid arthritis (RA), it is well known that rheumatoid synovial fibroblasts (RSF) produce matrix metalloproteinases (MMPs) when stimulated with proinflammatory cytokines such as...
A facile stereocontrolled approach to CF3-substituted triarylethenes: Synthesis of panomifene (2004)
Secondary structure analyses of protein films on gold surfaces by circular dichroism (2003)
Shimizu,M., Kazutoshi,K., Morii,H., Mitsui,K., Knoll,Wolfgang, Nagamune,T.
In order to analyze the secondary structures of protein molecules adsorbed on gold surfaces, circular dichroism (CD) spectra were measured and the secondary structure contents of protein ultra-thin...
Secondary structure analyses of protein films on gold surfaces by circular dichroism (2003)
Shimizu, M., Kazutoshi, K., Morii, H., Mitsui, K., Knoll, Wolfgang, Nagamune, T.
In order to analyze the secondary structures of protein molecules adsorbed on gold surfaces, circular dichroism (CD) spectra were measured and the secondary structure contents of protein ultra-thin...
Kataoka, T, Yunoki, E, Shimizu, M, Mori, T, Tsukamoto, O, Takahashi, S, ...
Kobayashi,K., Shimizu,M., Nagamune,T., Sasabe,H., Fang,Y., Knoll,Wolfgang
Association and dissociation reactions of cytochrome b(562) on solid surfaces were investigated by means of surface plasmon resonance spectroscopy. Propionates of side chains in the heme molecule...
Kumagai, T, Shimizu, M, Itaya, A, ...
Excited-state dynamics of 9,9'-biantryl (BA) adsorbed on the porous glass, where the large motion of the surrounding medium or intramolecular motion of BA was not plausible, and temperature effects...
Kobayashi, K., Shimizu, M., Nagamune, T., Sasabe, H., Fang, Y., Knoll, Wolfgang
Association and dissociation reactions of cytochrome b(562) on solid surfaces were investigated by means of surface plasmon resonance spectroscopy. Propionates of side chains in the heme molecule...
Geminal dimetalation of alkylidene-type carbenoids with silylboranes and diborons (2002)
Kurahashi, T, Hata, T, Masai, H, Kitagawa, H, Shimizu, M, Hiyama, T
A study of the atmospheric boundary layer using radon and air pollutants as tracers (2001)
Kataoka, T, Yunoki, E, Shimizu, M, Mori, T, Tsukamoto, O, Ohashi, Y, ...
Geminal difunctionalization of alkenylidene-type carbenoids by using interelement compounds (2001)
Hata, T, Kitagawa, H, Masai, H, Kurahashi, T, Shimizu, M, Hiyama, T
The Vienna classification of gastrointestinal epithelial neoplasia (2000)
Riddell, R H, Kato, Y, Borchard, F, Cooper, H S, Dawsey, S M, ...
BACKGROUND: Use of the conventional Western and Japanese classification systems of gastrointestinal epithelial neoplasia results in large differences among pathologists in the diagnosis of...
New nomenclature and DNA testing guidelines for myotonic dystrophy type 1(DM1) (2000)
Gonzalez, I, Ohsawa, N., Singer, R.H., Devillers, M., Ashizawa, T., Balasubramanyam, A., ...
Myotonic dystrophy (DM; OMIM 160900, also known as dystrophia myotonica, myotonia atrophica and Steinert disease) is an autosomal dominant myotonic myopathy associated with abnormalities of other...
Eotaxin contributes to renal interstitial eosinophilia (1999)
Wada, T, Furuichi, K, Sakai, N, Shimizu, M, Segawa, C, Kobayashi, K, ...
Fatigue Properties of Nitrided Ti-6Al-4V Alloy. (1998)
Morita, T., Shimizu, M., Kawasaki, K., Chiba, T.
The detrimental effect of nitriding on the fatigue strength of titanium alloy was assessed through some critical experiments concerning the fatigue properties of nitrided Ti-6Al-4V alloy including...
Furuichi, K, Wada, T, Shimizu, M, Segawa, C, Ohta, S, Takasawa, K, ...
Kataoka, T., Tsukamoto, O., Yunoki, E., Michihiro, K., Sugiyama, H., Shimizu, M., ...
Variation of 222Rn concentration in outdoor air, returns of a monostatic acoustic sounder and sensible heat flux are simultaneously observed at Okayama-shi in Japan. The sensible heat flux is...
FUNCTIONAL INTEGRAL METHOD IN ITINERANT ELECTRON MAGNETISM (1988)
Feynman's variational method and the arbitrariness of the Stratonovich-Hubbard transformation in the functional integral method are investigated. By making use of their results the dynamical spin...
Concentration dependence of the Curie temperature Tc of (R - Y) Co2 and R (Co - M)2 (R = heavy rare-earth, M = Al and Ni) is calculated by making use of a phonomenological model. Type of the magnetic...
MAGNETIC PROPERTIES OF CUBIC LAVES PHASE TRANSITION-METAL COMPOUNDS (1988)
Electronic structures of d-electrons in the cubic Laves phase transition-metal compounds are calculated in the tight-binding approximation. By making use of the calculated density-of-states curves,...
MAGNETIC PROPERTIES OF PSEUDOBINARY Y - (Fe, Co), Y - (Co, Ni) AND Y - (Ni, Cu) COMPOUNDS (1988)
Shimizu, M., Miyazaki, M., Inoue, J.
The magnetisation for pseudobinary compounds, Y (Fe - Co)n, Y (Co - Ni)n and Y (Ni - Cu)n with n = 3, 3.5, 5 and 8.5 and its temperature variation for Ni-rich Y2 (Co - Ni)7 and Y2 (Ni - Cu)7...
MAGNETOVOLUME EFFECT IN FERROMAGNETIC METALS : NUMERICAL RESULTS FOR BCC Fe AND FCC Ni (1988)
The magnetovolume effect in ferromagnetic bcc Fe and fcc Ni is estimated numerically in the fixed moment method by using the LMTO method and the local spin density approximation. The obtained results...
ONSET OF Mn MOMENT IN RMn2 COMPOUNDS (1988)
Electronic structures of d-electrons in heavy rare-earth R and manganese compounds RMn2 with the cubic Laves phase structure are calculated in the tight-binding approximation. A possibility of the...
FUNCTIONAL INTEGRAL METHOD IN ITINERANT ELECTRON MAGNETISM (1988)
Feynman's variational method and the arbitrariness of the Stratonovich-Hubbard transformation in the functional integral method are investigated. By making use of their results the dynamical spin...
Concentration dependence of the Curie temperature Tc of (R - Y) Co2 and R (Co - M)2 (R = heavy rare-earth, M = Al and Ni) is calculated by making use of a phonomenological model. Type of the magnetic...
MAGNETIC PROPERTIES OF CUBIC LAVES PHASE TRANSITION-METAL COMPOUNDS (1988)
Electronic structures of d-electrons in the cubic Laves phase transition-metal compounds are calculated in the tight-binding approximation. By making use of the calculated density-of-states curves,...
MAGNETIC PROPERTIES OF PSEUDOBINARY Y - (Fe, Co), Y - (Co, Ni) AND Y - (Ni, Cu) COMPOUNDS (1988)
Shimizu, M., Miyazaki, M., Inoue, J.
The magnetisation for pseudobinary compounds, Y (Fe - Co)n, Y (Co - Ni)n and Y (Ni - Cu)n with n = 3, 3.5, 5 and 8.5 and its temperature variation for Ni-rich Y2 (Co - Ni)7 and Y2 (Ni - Cu)7...
MAGNETOVOLUME EFFECT IN FERROMAGNETIC METALS : NUMERICAL RESULTS FOR BCC Fe AND FCC Ni (1988)
The magnetovolume effect in ferromagnetic bcc Fe and fcc Ni is estimated numerically in the fixed moment method by using the LMTO method and the local spin density approximation. The obtained results...
ONSET OF Mn MOMENT IN RMn2 COMPOUNDS (1988)
Electronic structures of d-electrons in heavy rare-earth R and manganese compounds RMn2 with the cubic Laves phase structure are calculated in the tight-binding approximation. A possibility of the...
FUNCTIONAL INTEGRAL METHOD IN ITINERANT ELECTRON MAGNETISM (1988)
Feynman's variational method and the arbitrariness of the Stratonovich-Hubbard transformation in the functional integral method are investigated. By making use of their results the dynamical spin...
Concentration dependence of the Curie temperature Tc of (R - Y) Co2 and R (Co - M)2 (R = heavy rare-earth, M = Al and Ni) is calculated by making use of a phonomenological model. Type of the magnetic...
MAGNETIC PROPERTIES OF CUBIC LAVES PHASE TRANSITION-METAL COMPOUNDS (1988)
Electronic structures of d-electrons in the cubic Laves phase transition-metal compounds are calculated in the tight-binding approximation. By making use of the calculated density-of-states curves,...
MAGNETIC PROPERTIES OF PSEUDOBINARY Y - (Fe, Co), Y - (Co, Ni) AND Y - (Ni, Cu) COMPOUNDS (1988)
Shimizu, M., Miyazaki, M., Inoue, J.
The magnetisation for pseudobinary compounds, Y (Fe - Co)n, Y (Co - Ni)n and Y (Ni - Cu)n with n = 3, 3.5, 5 and 8.5 and its temperature variation for Ni-rich Y2 (Co - Ni)7 and Y2 (Ni - Cu)7...
MAGNETOVOLUME EFFECT IN FERROMAGNETIC METALS : NUMERICAL RESULTS FOR BCC Fe AND FCC Ni (1988)
The magnetovolume effect in ferromagnetic bcc Fe and fcc Ni is estimated numerically in the fixed moment method by using the LMTO method and the local spin density approximation. The obtained results...
ONSET OF Mn MOMENT IN RMn2 COMPOUNDS (1988)
Electronic structures of d-electrons in heavy rare-earth R and manganese compounds RMn2 with the cubic Laves phase structure are calculated in the tight-binding approximation. A possibility of the...
Nucleotide sequence of a full-length cDNA for mouse cytosketetal {beta}-actin raRNA (1986)
ToIcunaga, K., Taniguchi, H., Yoda, K., Shimizu, M., Salciyama, S.
Shimizu, M., Tanabe, Y., Yoshioka, T., Takeda, K., Hamajima, T., Miki, N., ...
A toroidal coil system is probably preferable to a solenoid coil system in terms of stray magnetic field, fabrication, maintenance, and repair. Judging from the uncertain properties of rock masses...
Shimizu, M., Yoshioka, T., Morita, Y., Tanabe, Y., Hamajima, T., Fujiwara, N., ...
A conceptual design of a 10 GWh superconductive magnetic energy storage (SMES) for diurnal energy storage use is presented. A toroidal field coil arrangement is preferably adopted. The main advantage...
Shimizu, M., Morita, Y., Yukimatsu, Y., Tomozawa, T., Tanabe, Y., Takeda, N., ...
Problems concerning rock mass support system are examined and rock mass stability analysis for the conceptual design of the 10 GWH SMES system is carried out using F.E.M. under the condition of...
Shimizu, M., Tanabe, Y., Yoshioka, T., Takeda, K., Hamajima, T., Miki, N., ...
A toroidal coil system is probably preferable to a solenoid coil system in terms of stray magnetic field, fabrication, maintenance, and repair. Judging from the uncertain properties of rock masses...
Shimizu, M., Yoshioka, T., Morita, Y., Tanabe, Y., Hamajima, T., Fujiwara, N., ...
A conceptual design of a 10 GWh superconductive magnetic energy storage (SMES) for diurnal energy storage use is presented. A toroidal field coil arrangement is preferably adopted. The main advantage...
Shimizu, M., Morita, Y., Yukimatsu, Y., Tomozawa, T., Tanabe, Y., Takeda, N., ...
Problems concerning rock mass support system are examined and rock mass stability analysis for the conceptual design of the 10 GWH SMES system is carried out using F.E.M. under the condition of...
Shimizu, M., Tanabe, Y., Yoshioka, T., Takeda, K., Hamajima, T., Miki, N., ...
A toroidal coil system is probably preferable to a solenoid coil system in terms of stray magnetic field, fabrication, maintenance, and repair. Judging from the uncertain properties of rock masses...
Shimizu, M., Yoshioka, T., Morita, Y., Tanabe, Y., Hamajima, T., Fujiwara, N., ...
A conceptual design of a 10 GWh superconductive magnetic energy storage (SMES) for diurnal energy storage use is presented. A toroidal field coil arrangement is preferably adopted. The main advantage...
Shimizu, M., Morita, Y., Yukimatsu, Y., Tomozawa, T., Tanabe, Y., Takeda, N., ...
Problems concerning rock mass support system are examined and rock mass stability analysis for the conceptual design of the 10 GWH SMES system is carried out using F.E.M. under the condition of...
SPECTRAL STUDIES ON THE ELECTRONIC STRUCTURE OF POLYACETYLENE (1983)
Tanaka, J., Tanaka, M., Fujimoto, H., Shimizu, M., Sato, N., Inokuchi, H.
The change of the optical spectra of polyacetylene upon doping is studied by measurements of visible, infrared and photoelectron spectra. The infrared spectra of the doped film showed new peaks with...
SPECTRAL STUDIES ON THE ELECTRONIC STRUCTURE OF POLYACETYLENE (1983)
Tanaka, J., Tanaka, M., Fujimoto, H., Shimizu, M., Sato, N., Inokuchi, H.
The change of the optical spectra of polyacetylene upon doping is studied by measurements of visible, infrared and photoelectron spectra. The infrared spectra of the doped film showed new peaks with...
SPECTRAL STUDIES ON THE ELECTRONIC STRUCTURE OF POLYACETYLENE (1983)
Tanaka, J., Tanaka, M., Fujimoto, H., Shimizu, M., Sato, N., Inokuchi, H.
The change of the optical spectra of polyacetylene upon doping is studied by measurements of visible, infrared and photoelectron spectra. The infrared spectra of the doped film showed new peaks with...
Itinerant electron metamagnetism (1982)
Rigorous conditions for the metamagnetic transitions between the paramagnetic and ferromagnetic states and between the weak ferromagnetic and normal ferromagnetic states are derived. The expressions...
Magnetic phase transitions in itinerant electron system (1982)
Various combinations of the first-order and second-order magnetic phase transitions in itinerant electron systems are shown. The comparison with experiment is discussed.
Itinerant electron metamagnetism (1982)
Rigorous conditions for the metamagnetic transitions between the paramagnetic and ferromagnetic states and between the weak ferromagnetic and normal ferromagnetic states are derived. The expressions...
Magnetic phase transitions in itinerant electron system (1982)
Various combinations of the first-order and second-order magnetic phase transitions in itinerant electron systems are shown. The comparison with experiment is discussed.
Itinerant electron metamagnetism (1982)
Rigorous conditions for the metamagnetic transitions between the paramagnetic and ferromagnetic states and between the weak ferromagnetic and normal ferromagnetic states are derived. The expressions...
Magnetic phase transitions in itinerant electron system (1982)
Various combinations of the first-order and second-order magnetic phase transitions in itinerant electron systems are shown. The comparison with experiment is discussed.
ORDERING IN COMMERCIAL SILICON STEELS (1979)
Shimizu, M., Honsako, T., Fujimoto, K.
Probability of occurrence of three kinds of iron atoms is measured using Mössbauer spectroscopy at room temperature in commercial silicon steels. Probability obtained shows a marked deviation from...
ORDERING IN COMMERCIAL SILICON STEELS (1979)
Shimizu, M., Honsako, T., Fujimoto, K.
Probability of occurrence of three kinds of iron atoms is measured using Mössbauer spectroscopy at room temperature in commercial silicon steels. Probability obtained shows a marked deviation from...
ORDERING IN COMMERCIAL SILICON STEELS (1979)
Shimizu, M., Honsako, T., Fujimoto, K.
Probability of occurrence of three kinds of iron atoms is measured using Mössbauer spectroscopy at room temperature in commercial silicon steels. Probability obtained shows a marked deviation from...
SPIN SUSCEPTIBILITIES OF FERROMAGNETIC Pd-Ni and Pt-Ni Alloys (1974)
Generalized spin susceptibility of ferromagnetic alloys is calculated within the random phase approximation under the assumption of perfect local screening. Using this result, uniform spin...
SPIN SUSCEPTIBILITIES OF FERROMAGNETIC Pd-Ni and Pt-Ni Alloys (1974)
Generalized spin susceptibility of ferromagnetic alloys is calculated within the random phase approximation under the assumption of perfect local screening. Using this result, uniform spin...
SPIN SUSCEPTIBILITIES OF FERROMAGNETIC Pd-Ni and Pt-Ni Alloys (1974)
Generalized spin susceptibility of ferromagnetic alloys is calculated within the random phase approximation under the assumption of perfect local screening. Using this result, uniform spin...
ITINERANT ELECTRON FERROMAGNETISM IN INVAR ALLOYS (1971)
The temperature dependence of the magnetization and the magnetic susceptibility for fcc Fe-Ni Invar alloys are discussed qualitatively and quantitatively in the model of itinerant electron...
ITINERANT ELECTRON FERROMAGNETISM IN INVAR ALLOYS (1971)
The temperature dependence of the magnetization and the magnetic susceptibility for fcc Fe-Ni Invar alloys are discussed qualitatively and quantitatively in the model of itinerant electron...
ITINERANT ELECTRON FERROMAGNETISM IN INVAR ALLOYS (1971)
The temperature dependence of the magnetization and the magnetic susceptibility for fcc Fe-Ni Invar alloys are discussed qualitatively and quantitatively in the model of itinerant electron...
Kato, Yukio, 加藤, 幸夫, カトウ, ユキオ, Katō, Yukio, Shimizu, M., Igarashi, A., ...
We characterized human bone marrow-derived mesenchymal stem cells (MSC) by identification of molecular markers and used these markers in clinical studies for treatment of periodontal disease:...
New nomenclature and DNA testing guidelines for myotonic dystrophy type 1(DM1)
Gonzalez, I, Ohsawa, N., Singer, R.H., Devillers, M., Ashizawa, T., Balasubramanyam, A., ...
Myotonic dystrophy (DM; OMIM 160900, also known as dystrophia myotonica, myotonia atrophica and Steinert disease) is an autosomal dominant myotonic myopathy associated with abnormalities of other...
Jaworski, A, Rosche, W A, Gellibolian, R, Kang, S, Shimizu, M, Bowater, R P, ...
Long CTG triplet repeats which are associated with several human hereditary neuromuscular disease genes are stabilized in ColE1-derived plasmids in Escherichia coli containing mutations in the...
Synthesis of receptor antagonists of neuropeptide Y.
Tatemoto, K, Mann, M J, Shimizu, M
We report the synthesis of receptor antagonists of neuropeptide Y (NPY) by a strategy based on synthesis of mixtures of analogs and the subsequent isolation and identification of receptor antagonists...
Dynamics in the isomerization of intramolecular DNA triplexes in supercoiled plasmids.
Shindo, H, Matsumoto, N, Shimizu, M
We report here kinetic and thermodynamic studies on differential isomerization of intramolecular Pyr*Pur.Pyr triplexes in supercoiled plasmids. Two structural isomers of the triplex exist: one with...
Shimizu, M, Li, W, Covitz, P A, Hara, M, Shindo, H, Mitchell, A P
The zinc finger protein Rme1p is a negative regulator of the meiotic activator IME1 in Saccharomyces cerevisiae . Prior studies have shown that Rme1p binds in vitro to a site near nt -2030 in the...
Nishizawa, M, Shimizu, M, Ohkawa, H, Kanaoka, M
The gene coding for a novel esterase which stereoselectively hydrolyzes the (+)-trans (1R,3R) stereoisomer of ethyl chrysanthemate was cloned from Arthrobacter globiformis SC-6-98-28 and...
Okazaki, M, Sugita, T, Shimizu, M, Ohode, Y, Iwamoto, K, ...
The Mn(2+)-oxidizing bacterium Pseudomonas fluorescens GB-1 deposits Mn oxide around the cell. During growth of a culture, the Mn(2+)-oxidizing activity of the cells first appeared in the early...
Pharmacokinetics of a novel quinolone, AT-4140, in animals.
Nakamura, S, Kurobe, N, Ohue, T, Hashimoto, M, Shimizu, M
The pharmacokinetics of 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(cis-3,5-dimethyl-1- piperazinyl)-4-oxoquinoline-3-carboxylic acid (AT-4140) in experimental animals given a single oral dose...
In vitro antibacterial properties of AT-2266, a new pyridonecarboxylic acid.
Nakamura, S, Minami, A, Katae, H, Inoue, S, Yamagishi, J, Takase, Y, ...
AT-2266, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3 -carboxylic acid, is a new pyridonecarboxylic acid derivative with broad and potent antibacterial activity. It...
Nakamura, S, Nakata, K, Katae, H, Minami, A, Kashimoto, S, Yamagishi, J, ...
AT-2266 (1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1, 8-naphthyridine-3-carboxylic acid) showed marked activity in vivo when administered orally to mice bearing systemic, pulmonary,...
Mima, T, Saeki, Y, Ohshima, S, Nishimoto, N, Matsushita, M, Shimizu, M, ...
To investigate the pathogenicity of T cells infiltrating in the rheumatoid joints, mononuclear cells (MNC), predominantly T cells, isolated from either synovial fluid or synovial tissues of the...
Oeda, K, Inouye, K, Ibuchi, Y, Oshie, K, Shimizu, M, Nakamura, K, ...
Escherichia coli JM103 cells harboring expression plasmid pTB1 or pKC6 synthesized the 130- and 135-kilodalton insecticidal proteins, respectively, of Bacillus thuringiensis subsp. aizawai IPL7, and...
New nalidixic acid resistance mutations related to deoxyribonucleic acid gyrase activity.
Yamagishi, J, Furutani, Y, Inoue, S, Ohue, T, Nakamura, S, Shimizu, M
In Escherichia coli K-12 mutants which had a new nalidixic acid resistance mutation at about 82 min on the chromosome map, cell growth was resistant to or hypersusceptible to nalidixic acid, oxolinic...
The G1/S boundary-specific enhancer of the rat cdc2 promoter.
Shimizu, M, Ichikawa, E, Inoue, U, Nakamura, T, Nakajima, T, Nojima, H, ...
Multiple species of G1 cyclins and cyclin-dependent kinases are induced sequentially during G1 phase, and the expression of cyclin A and cdc2 genes is subsequently induced at the G1/S boundary. To...
Shimizu, M, Shirai, J, Narita, M, Yamane, T
A cytopathic astrovirus was isolated from pigs with acute diarrhea in an established cell line that was derived from porcine embryonic kidneys with the aid of trypsin. The virus showed a distinct...
Tsunemitsu, H, Saif, L J, Jiang, B M, Shimizu, M, Hiro, M, Yamaguchi, H, ...
A virus (designated the Shintoku strain) which was morphologically indistinguishable from group A rotaviruses was detected in the feces of adult cows with diarrhea in Japan. The virus contained 11...
A micro-indirect hemagglutination (IHA) test was developed for detecting antibody against transmissible gastroenteritis (TGE) virus of pigs. TGE virus propagated in swine kidney cell cultures was...
Intramolecular DNA triplexes in supercoiled plasmids.
Hanvey, J C, Shimizu, M, Wells, R D
A series of inserts with oligopurine.oligopyrimidine mirror repeat sequences was investigated at the base pair level with specific chemical probes (OsO4 and diethylpyrocarbonate) to evaluate the in...
Demonstration of an in vivo functional beta 3-adrenoceptor in man.
Enocksson, S, Shimizu, M, Lönnqvist, F, Nordenström, J, Arner, P
Although it is well established in several mammalian species that beta 3-adrenoceptors play a major role in regulating lipolysis and thermogenesis in adipose tissue, the functional existence and role...
Hirano, T, Taga, T, Yasukawa, K, Nakajima, K, Nakano, N, Takatsuki, F, ...
The partial amino acid sequence of the NH2 terminus of a factor named human B-cell differentiation factor or B-cell stimulatory factor 2 (BSF-2) has been determined. Antibodies raised against the...
Identity elements of Saccharomyces cerevisiae tRNA(His).
Nameki, N, Asahara, H, Shimizu, M, Okada, N, Himeno, H
Recognition of tRNA(His) by Saccharomyces cerevisiae histidyl-tRNA synthetase was studied using in vitro transcripts. Histidine tRNA is unique in possessing an extra nucleotide, G-1, at the 5' end....
DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo.
Murphy, M R, Shimizu, M, Roth, S Y, Dranginis, A M, Simpson, R T
Two homodimeric proteins, alpha 2 and MCM1, are required to repress transcription of a-cell type specific genes in haploid yeast alpha-cells. In vitro studies by others of the interactions of these...
Preferential binding of E.coli histone-like protein HU alpha to negatively supercoiled DNA.
Shindo, H, Furubayashi, A, Shimizu, M, Miyake, M, Imamoto, F
Binding specificity of histone-like HU alpha protein to supercoiled DNA was examined by gel retardation assay and chemical probing with OsO4. The latter method was proved to be a unique means for...
Yabusaki, Y, Shimizu, M, Murakami, H, Nakamura, K, Oeda, K, Ohkawa, H
We constructed a full-length cDNA coding for 3-methylcholanthrene-inducible rat liver cytochrome P-450MC by the method of Okayama and Berg. The isolated clone pAU157 contained the cDNA insert of 2.7...
Identity determinants of E. coli tryptophan tRNA.
Himeno, H, Hasegawa, T, Asahara, H, Tamura, K, Shimizu, M
The first base pair of the acceptor stem A1-U72 and the discriminator base G73, as well as the anticodon nucleotides, characterize the tryptophan tRNA in E. coli. To determine the contribution of...
Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix.
Hanvey, J C, Shimizu, M, Wells, R D
The ability of oligopyrimidines to inhibit, through triple helix formation, the specific protein-DNA interactions of the EcoRI restriction and modification enzymes (EcoRI and MEcoRI) with their...
Conversion of aminoacylation specificity from tRNA(Tyr) to tRNA(Ser) in vitro.
Himeno, H, Hasegawa, T, Ueda, T, Watanabe, K, Shimizu, M
The discrimination mechanism between tRNA(Ser) and tRNA(Tyr) was studied using various in vitro transcripts of E. coli tRNATyr variants. The insertion of only two nucleotides into the variable stem...
Role of the extra G-C pair at the end of the acceptor stem of tRNA(His) in aminoacylation.
Himeno, H, Hasegawa, T, Ueda, T, Watanabe, K, Miura, K, Shimizu, M
All sequenced histidine tRNAs have one additional nucleotide at the 5' end compared with other tRNA species. To investigate the role of this unique structure in aminoacylation, we constructed in...
Honda, T, Shimizu, M, Takeda, Y, Miwatani, T
A factor changing Chinese hamster ovary cells from an oval to a spindle shape was isolated from the culture filtrate of Vibrio parahaemolyticus. It was partially purified by successive column...
Shimizu, M, Roth, S Y, Szent-Gyorgyi, C, Simpson, R T
Analysis of the chromatin structure of minichromosomes containing the binding site for the yeast alpha 2 repressor protein by indirect end-labeling has previously indicated that nucleosomes are...
Endometrial ossification in a postmenopausal woman.
A case of endometrial ossification in a 62 year old woman is reported. The patient presented with increased vaginal discharge. On transvaginal ultrasonography, a hyperechoic area within the uterine...
Lithium associated autoimmune thyroiditis.
Shimizu, M, Hirokawa, M, Manabe, T, Shimozuma, K, Sonoo, H, Harada, T
A case of autoimmune thyroiditis after long term treatment with lithium is described in a 29 year old Japanese woman with manic depression. Positive serum antithyroglobulin and antimicrosomal...
A simple technique for identifying the adrenal glands at necropsy.
Shimizu, M, Sakurai, T, Tadaoka, Y
There is no detailed and practical description of how to identify the adrenal glands at necropsy. A simple technique is described, based on anatomical location. After removing the aorta by the...
Shimizu, T, Shimizu, M, Kawaguchi, K, Yomura, W, Ihara, Y, Matsumoto, T
A case of mucinous cystadenoma mimicking ovarian cancer is reported. Serum carcinoembryonic antigen (CEA) concentration was raised, and computed tomography of the abdomen and pelvis demonstrated a...
Solitary cystic dilatation of the intrahepatic bile duct.
Ohmoto, K, Shimizu, M, Iguchi, Y, Yamamoto, S, Murakami, M, Tsunoda, T
A 31 year old man was hospitalised with general fatigue and epigastric pain. Abdominal ultrasonography, computed tomography, and magnetic resonance imaging showed a cystic lesion in the left lobe of...
Tumorous necrotic nodule in the liver: unexpected effect of the microwave tissue coagulator.
Mikami, Y, Shimizu, M, Manabe, T
The microwave tissue coagulator (MTC) is used in hepatectomy because it provides excellent haemostasis during the procedure. A 59 year old man underwent partial hepatic lobectomy with MTC, for...
Shimizu, M, Manabe, T, Matsumoto, T, Monobe, Y, Hirokawa, M, Moriya, T, ...
Two cases of beta 2 microglobulin amyloidosis following long term haemodialysis found during necropsy are reported. The patients were 59 and 65 year old Japanese men, respectively. In both cases,...
Histological assessment of chronic pancreatitis at necropsy.
Shimizu, M, Hirokawa, M, Manabe, T
AIMS: To evaluate the histological criteria used to diagnose chronic pancreatitis; and to assess interobserver variation among general pathologists. METHODS: Forty five cases of chronic pancreatitis...
Intraepithelial haemorrhage of the oesophagus: a terminal event in haematological disorders.
Shimizu, M, Matsumoto, T, Hirokawa, M, Monobe, Y, Iida, M, Manabe, T
AIMS: To investigate the clinicopathological findings in cases with intraepithelial haemorrhage of the oesophagus (IHO). METHODS: Necropsy records and the histopathology findings in the oesophagus...
Collagen remodelling in myocardia of patients with diabetes.
Shimizu, M, Umeda, K, Sugihara, N, Yoshio, H, Ino, H, Takeda, R, ...
AIMS: To investigate collagen remodelling in the interstitium of the heart in patients with diabetes. METHODS: Immunohistochemical study of the biopsied myocardium using type specific anticollagen...
Matsumoto, T, Mizuno, M, Shimizu, M, Manabe, T, Iida, M
AIM: Serrated adenoma is a recently described category of colorectal adenoma. The aim of this study was to determine whether serrated adenomas have clinicopathological findings distinct from...
High-Mr glycoprotein profiles in human milk serum and fat-globule membrane.
Shimizu, M, Yamauchi, K, Miyauchi, Y, Sakurai, T, Tokugawa, K, McIlhinney, R A
Gradient-polyacrylamide-gel electrophoresis of human milk serum separated three high-Mr glycoprotein bands. The properties of the components corresponding to the three bands (tentatively termed...
Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
Shimizu, T, Toumoto, A, Ihara, K, Shimizu, M, Kyogoku, Y, Ogawa, N, ...
The crystal structure of a DNA-binding domain of PHO4 complexed with DNA at 2.8 A resolution revealed that the domain folds into a basic-helix-loop-helix (bHLH) motif with a long but compact loop...
Enhanced calcium response to serotonin in platelets from patients with affective disorders.
Yamawaki, S, Kagaya, A, Okamoto, Y, Shimizu, M, Nishida, A, Uchitomi, Y
In this report we have investigated the intracellular calcium (Ca2+) mobilization mediated by serotonin 5-HT2A receptors in the platelets of 13 patients with bipolar disorder and 12 patients with...
Nishizawa, M., Shimizu, M., Ohkawa, H., Kanaoka, M.
Volume 61, no. 9, p. 3209, column 2, line 23: "L22165" should read "L22516."
Shimizu, M, Egashira, T, Takahama, U
Photodynamic damage of Neurospora crassa conidia was studied in the presence of the photosensitizing dye, toluidine blue O. Conidia which germinated to form colonies decreased in number as...
In vitro study of E.coli tRNA(Arg) and tRNA(Lys) identity elements.
Tamura, K, Himeno, H, Asahara, H, Hasegawa, T, Shimizu, M
Various tRNA transcripts were constructed to study the identity elements of E.coli tRNA(Arg) and tRNA(Lys). Exchange of the anticodon of the major tRNA(Arg) from ACG to either CCG or CCU did not...
Jaworski, A, Rosche, W A, Gellibolian, R, Kang, S, Shimizu, M, Bowater, R P, ...
Long CTG triplet repeats which are associated with several human hereditary neuromuscular disease genes are stabilized in ColE1-derived plasmids in Escherichia coli containing mutations in the...
Synthesis of receptor antagonists of neuropeptide Y.
Tatemoto, K, Mann, M J, Shimizu, M
We report the synthesis of receptor antagonists of neuropeptide Y (NPY) by a strategy based on synthesis of mixtures of analogs and the subsequent isolation and identification of receptor antagonists...
Dynamics in the isomerization of intramolecular DNA triplexes in supercoiled plasmids.
Shindo, H, Matsumoto, N, Shimizu, M
We report here kinetic and thermodynamic studies on differential isomerization of intramolecular Pyr*Pur.Pyr triplexes in supercoiled plasmids. Two structural isomers of the triplex exist: one with...
Shimizu, M, Li, W, Covitz, P A, Hara, M, Shindo, H, Mitchell, A P
The zinc finger protein Rme1p is a negative regulator of the meiotic activator IME1 in Saccharomyces cerevisiae . Prior studies have shown that Rme1p binds in vitro to a site near nt -2030 in the...
Nishizawa, M, Shimizu, M, Ohkawa, H, Kanaoka, M
The gene coding for a novel esterase which stereoselectively hydrolyzes the (+)-trans (1R,3R) stereoisomer of ethyl chrysanthemate was cloned from Arthrobacter globiformis SC-6-98-28 and...
Okazaki, M, Sugita, T, Shimizu, M, Ohode, Y, Iwamoto, K, ...
The Mn(2+)-oxidizing bacterium Pseudomonas fluorescens GB-1 deposits Mn oxide around the cell. During growth of a culture, the Mn(2+)-oxidizing activity of the cells first appeared in the early...
Pharmacokinetics of a novel quinolone, AT-4140, in animals.
Nakamura, S, Kurobe, N, Ohue, T, Hashimoto, M, Shimizu, M
The pharmacokinetics of 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(cis-3,5-dimethyl-1- piperazinyl)-4-oxoquinoline-3-carboxylic acid (AT-4140) in experimental animals given a single oral dose...
In vitro antibacterial properties of AT-2266, a new pyridonecarboxylic acid.
Nakamura, S, Minami, A, Katae, H, Inoue, S, Yamagishi, J, Takase, Y, ...
AT-2266, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3 -carboxylic acid, is a new pyridonecarboxylic acid derivative with broad and potent antibacterial activity. It...
Nakamura, S, Nakata, K, Katae, H, Minami, A, Kashimoto, S, Yamagishi, J, ...
AT-2266 (1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1, 8-naphthyridine-3-carboxylic acid) showed marked activity in vivo when administered orally to mice bearing systemic, pulmonary,...
Mima, T, Saeki, Y, Ohshima, S, Nishimoto, N, Matsushita, M, Shimizu, M, ...
To investigate the pathogenicity of T cells infiltrating in the rheumatoid joints, mononuclear cells (MNC), predominantly T cells, isolated from either synovial fluid or synovial tissues of the...
Oeda, K, Inouye, K, Ibuchi, Y, Oshie, K, Shimizu, M, Nakamura, K, ...
Escherichia coli JM103 cells harboring expression plasmid pTB1 or pKC6 synthesized the 130- and 135-kilodalton insecticidal proteins, respectively, of Bacillus thuringiensis subsp. aizawai IPL7, and...
New nalidixic acid resistance mutations related to deoxyribonucleic acid gyrase activity.
Yamagishi, J, Furutani, Y, Inoue, S, Ohue, T, Nakamura, S, Shimizu, M
In Escherichia coli K-12 mutants which had a new nalidixic acid resistance mutation at about 82 min on the chromosome map, cell growth was resistant to or hypersusceptible to nalidixic acid, oxolinic...
Shimizu, M, Egashira, T, Takahama, U
Photodynamic damage of Neurospora crassa conidia was studied in the presence of the photosensitizing dye, toluidine blue O. Conidia which germinated to form colonies decreased in number as...
The G1/S boundary-specific enhancer of the rat cdc2 promoter.
Shimizu, M, Ichikawa, E, Inoue, U, Nakamura, T, Nakajima, T, Nojima, H, ...
Multiple species of G1 cyclins and cyclin-dependent kinases are induced sequentially during G1 phase, and the expression of cyclin A and cdc2 genes is subsequently induced at the G1/S boundary. To...
Shimizu, M, Shirai, J, Narita, M, Yamane, T
A cytopathic astrovirus was isolated from pigs with acute diarrhea in an established cell line that was derived from porcine embryonic kidneys with the aid of trypsin. The virus showed a distinct...
Tsunemitsu, H, Saif, L J, Jiang, B M, Shimizu, M, Hiro, M, Yamaguchi, H, ...
A virus (designated the Shintoku strain) which was morphologically indistinguishable from group A rotaviruses was detected in the feces of adult cows with diarrhea in Japan. The virus contained 11...
A micro-indirect hemagglutination (IHA) test was developed for detecting antibody against transmissible gastroenteritis (TGE) virus of pigs. TGE virus propagated in swine kidney cell cultures was...
Intramolecular DNA triplexes in supercoiled plasmids.
Hanvey, J C, Shimizu, M, Wells, R D
A series of inserts with oligopurine.oligopyrimidine mirror repeat sequences was investigated at the base pair level with specific chemical probes (OsO4 and diethylpyrocarbonate) to evaluate the in...
Demonstration of an in vivo functional beta 3-adrenoceptor in man.
Enocksson, S, Shimizu, M, Lönnqvist, F, Nordenström, J, Arner, P
Although it is well established in several mammalian species that beta 3-adrenoceptors play a major role in regulating lipolysis and thermogenesis in adipose tissue, the functional existence and role...
Hirano, T, Taga, T, Yasukawa, K, Nakajima, K, Nakano, N, Takatsuki, F, ...
The partial amino acid sequence of the NH2 terminus of a factor named human B-cell differentiation factor or B-cell stimulatory factor 2 (BSF-2) has been determined. Antibodies raised against the...
Identity elements of Saccharomyces cerevisiae tRNA(His).
Nameki, N, Asahara, H, Shimizu, M, Okada, N, Himeno, H
Recognition of tRNA(His) by Saccharomyces cerevisiae histidyl-tRNA synthetase was studied using in vitro transcripts. Histidine tRNA is unique in possessing an extra nucleotide, G-1, at the 5' end....
DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo.
Murphy, M R, Shimizu, M, Roth, S Y, Dranginis, A M, Simpson, R T
Two homodimeric proteins, alpha 2 and MCM1, are required to repress transcription of a-cell type specific genes in haploid yeast alpha-cells. In vitro studies by others of the interactions of these...
Preferential binding of E.coli histone-like protein HU alpha to negatively supercoiled DNA.
Shindo, H, Furubayashi, A, Shimizu, M, Miyake, M, Imamoto, F
Binding specificity of histone-like HU alpha protein to supercoiled DNA was examined by gel retardation assay and chemical probing with OsO4. The latter method was proved to be a unique means for...
In vitro study of E.coli tRNA(Arg) and tRNA(Lys) identity elements.
Tamura, K, Himeno, H, Asahara, H, Hasegawa, T, Shimizu, M
Various tRNA transcripts were constructed to study the identity elements of E.coli tRNA(Arg) and tRNA(Lys). Exchange of the anticodon of the major tRNA(Arg) from ACG to either CCG or CCU did not...
Yabusaki, Y, Shimizu, M, Murakami, H, Nakamura, K, Oeda, K, Ohkawa, H
We constructed a full-length cDNA coding for 3-methylcholanthrene-inducible rat liver cytochrome P-450MC by the method of Okayama and Berg. The isolated clone pAU157 contained the cDNA insert of 2.7...
Identity determinants of E. coli tryptophan tRNA.
Himeno, H, Hasegawa, T, Asahara, H, Tamura, K, Shimizu, M
The first base pair of the acceptor stem A1-U72 and the discriminator base G73, as well as the anticodon nucleotides, characterize the tryptophan tRNA in E. coli. To determine the contribution of...
Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix.
Hanvey, J C, Shimizu, M, Wells, R D
The ability of oligopyrimidines to inhibit, through triple helix formation, the specific protein-DNA interactions of the EcoRI restriction and modification enzymes (EcoRI and MEcoRI) with their...
Conversion of aminoacylation specificity from tRNA(Tyr) to tRNA(Ser) in vitro.
Himeno, H, Hasegawa, T, Ueda, T, Watanabe, K, Shimizu, M
The discrimination mechanism between tRNA(Ser) and tRNA(Tyr) was studied using various in vitro transcripts of E. coli tRNATyr variants. The insertion of only two nucleotides into the variable stem...
Role of the extra G-C pair at the end of the acceptor stem of tRNA(His) in aminoacylation.
Himeno, H, Hasegawa, T, Ueda, T, Watanabe, K, Miura, K, Shimizu, M
All sequenced histidine tRNAs have one additional nucleotide at the 5' end compared with other tRNA species. To investigate the role of this unique structure in aminoacylation, we constructed in...
Honda, T, Shimizu, M, Takeda, Y, Miwatani, T
A factor changing Chinese hamster ovary cells from an oval to a spindle shape was isolated from the culture filtrate of Vibrio parahaemolyticus. It was partially purified by successive column...
Shimizu, M, Roth, S Y, Szent-Gyorgyi, C, Simpson, R T
Analysis of the chromatin structure of minichromosomes containing the binding site for the yeast alpha 2 repressor protein by indirect end-labeling has previously indicated that nucleosomes are...
Endometrial ossification in a postmenopausal woman.
A case of endometrial ossification in a 62 year old woman is reported. The patient presented with increased vaginal discharge. On transvaginal ultrasonography, a hyperechoic area within the uterine...
Lithium associated autoimmune thyroiditis.
Shimizu, M, Hirokawa, M, Manabe, T, Shimozuma, K, Sonoo, H, Harada, T
A case of autoimmune thyroiditis after long term treatment with lithium is described in a 29 year old Japanese woman with manic depression. Positive serum antithyroglobulin and antimicrosomal...
A simple technique for identifying the adrenal glands at necropsy.
Shimizu, M, Sakurai, T, Tadaoka, Y
There is no detailed and practical description of how to identify the adrenal glands at necropsy. A simple technique is described, based on anatomical location. After removing the aorta by the...
Shimizu, T, Shimizu, M, Kawaguchi, K, Yomura, W, Ihara, Y, Matsumoto, T
A case of mucinous cystadenoma mimicking ovarian cancer is reported. Serum carcinoembryonic antigen (CEA) concentration was raised, and computed tomography of the abdomen and pelvis demonstrated a...
Solitary cystic dilatation of the intrahepatic bile duct.
Ohmoto, K, Shimizu, M, Iguchi, Y, Yamamoto, S, Murakami, M, Tsunoda, T
A 31 year old man was hospitalised with general fatigue and epigastric pain. Abdominal ultrasonography, computed tomography, and magnetic resonance imaging showed a cystic lesion in the left lobe of...
Tumorous necrotic nodule in the liver: unexpected effect of the microwave tissue coagulator.
Mikami, Y, Shimizu, M, Manabe, T
The microwave tissue coagulator (MTC) is used in hepatectomy because it provides excellent haemostasis during the procedure. A 59 year old man underwent partial hepatic lobectomy with MTC, for...
Shimizu, M, Manabe, T, Matsumoto, T, Monobe, Y, Hirokawa, M, Moriya, T, ...
Two cases of beta 2 microglobulin amyloidosis following long term haemodialysis found during necropsy are reported. The patients were 59 and 65 year old Japanese men, respectively. In both cases,...
Histological assessment of chronic pancreatitis at necropsy.
Shimizu, M, Hirokawa, M, Manabe, T
AIMS: To evaluate the histological criteria used to diagnose chronic pancreatitis; and to assess interobserver variation among general pathologists. METHODS: Forty five cases of chronic pancreatitis...
Intraepithelial haemorrhage of the oesophagus: a terminal event in haematological disorders.
Shimizu, M, Matsumoto, T, Hirokawa, M, Monobe, Y, Iida, M, Manabe, T
AIMS: To investigate the clinicopathological findings in cases with intraepithelial haemorrhage of the oesophagus (IHO). METHODS: Necropsy records and the histopathology findings in the oesophagus...
Collagen remodelling in myocardia of patients with diabetes.
Shimizu, M, Umeda, K, Sugihara, N, Yoshio, H, Ino, H, Takeda, R, ...
AIMS: To investigate collagen remodelling in the interstitium of the heart in patients with diabetes. METHODS: Immunohistochemical study of the biopsied myocardium using type specific anticollagen...
Matsumoto, T, Mizuno, M, Shimizu, M, Manabe, T, Iida, M
AIM: Serrated adenoma is a recently described category of colorectal adenoma. The aim of this study was to determine whether serrated adenomas have clinicopathological findings distinct from...
High-Mr glycoprotein profiles in human milk serum and fat-globule membrane.
Shimizu, M, Yamauchi, K, Miyauchi, Y, Sakurai, T, Tokugawa, K, McIlhinney, R A
Gradient-polyacrylamide-gel electrophoresis of human milk serum separated three high-Mr glycoprotein bands. The properties of the components corresponding to the three bands (tentatively termed...
Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
Shimizu, T, Toumoto, A, Ihara, K, Shimizu, M, Kyogoku, Y, Ogawa, N, ...
The crystal structure of a DNA-binding domain of PHO4 complexed with DNA at 2.8 A resolution revealed that the domain folds into a basic-helix-loop-helix (bHLH) motif with a long but compact loop...
Enhanced calcium response to serotonin in platelets from patients with affective disorders.
Yamawaki, S, Kagaya, A, Okamoto, Y, Shimizu, M, Nishida, A, Uchitomi, Y
In this report we have investigated the intracellular calcium (Ca2+) mobilization mediated by serotonin 5-HT2A receptors in the platelets of 13 patients with bipolar disorder and 12 patients with...
Nishizawa, M., Shimizu, M., Ohkawa, H., Kanaoka, M.
Volume 61, no. 9, p. 3209, column 2, line 23: "L22165" should read "L22516."
Kato, Yukio, 加藤, 幸夫, カトウ, ユキオ, Katō, Yukio, Shimizu, M., Igarashi, A., ...
We characterized human bone marrow-derived mesenchymal stem cells (MSC) by identification of molecular markers and used these markers in clinical studies for treatment of periodontal disease:...
Analysis of electrophoretic mobility histogram of mouse thymocytes during tumour development.
Iwaguchi, T, Shimizu, M, Mori, T, Nakajima, T
The population of medullary thymocytes without peanut agglutinin (PNA) receptor consisted of two groups: Lyt-1+ .2- cells with a high mobility of 1.0 micrometer/sec/V/cm, and Lyt-1+ .2+ cells with a...
New nomenclature and DNA testing guidelines for myotonic dystrophy type 1(DM1)
Gonzalez, I, Ohsawa, N., Singer, R.H., Devillers, M., Ashizawa, T., Balasubramanyam, A., ...
Myotonic dystrophy (DM; OMIM 160900, also known as dystrophia myotonica, myotonia atrophica and Steinert disease) is an autosomal dominant myotonic myopathy associated with abnormalities of other...
The Vienna classification of gastrointestinal epithelial neoplasia
Schlemper, R, Riddell, R, Kato, Y, Borchard, F, Cooper, H, Dawsey, S, ...
BACKGROUND—Use of the conventional Western and Japanese classification systems of gastrointestinal epithelial neoplasia results in large differences among pathologists in the diagnosis of...
Shimizu, M, Sugihara, N, Kita, Y, Shimizu, K, Horita, Y, Nakajima, K, ...
OBJECTIVE--To investigate the relation between regional myocardial sympathetic nerve activity and the electrocardiographic and cardiac functional changes in hypertrophic cardiomyopathy. DESIGN--A...
Increased left atrial chamber stiffness in hypertrophic cardiomyopathy.
Sanada, H, Shimizu, M, Sugihara, N, Shimizu, K, Ino, H, Takeda, R
OBJECTIVE--To investigate left atrial chamber stiffness and its influence on left atrial and left ventricular functions in hypertrophic cardiomyopathy. DESIGN--Prospective study. SETTING--Department...
Cavernous haemangioma in the coronary sinus
Yamaguchi, M, Shimizu, M, Mabuchi, H
A 58 year old man with a history of cerebral infarction was admitted to hospital with chest discomfort and dyspnoea. He had no history of precordial chest discomfort. Angiography and left...
QT dispersion and left ventricular morphology in patients with hypertrophic cardiomyopathy
Sakata, K, Shimizu, M, Ino, H, Yamaguchi, M, Terai, H, Hayashi, K, ...
Objective: To evaluate the relation between QT variables and disproportion of left ventricular wall hypertrophy in patients with hypertrophic cardiomyopathy.
Serum IgE levels and reaginic-type skin reactions in sarcoidosis.
Yagura, T, Shimizu, M, Yamamura, Y, Tachibana, T
Immunoglobulin E (IgE) levels in sera of eighty-four patients with sarcoidosis and fifty-one apparently healthy controls were measured by means of a radioimmunosorbent test (RIST). A significant...
Non-Hodgkin's lymphomas. analysis of 109 Japanese cases with the use of LSGJ classification.
Shimizu, M., Miura, M., Kitahara, M., Katayama, I.
Recently the Lymphoma Study Group of Japan (LSGJ) proposed a new classification of non-Hodgkin's lymphomas (NHLs), diving NHLs into the follicular group consisting of three subsets and the diffuse...
Clinical pharmacology of a new antidepressant, Y-8894 in healthy young and elderly volunteers.
Ogura, C, Kishimoto, A, Kunimoto, N, Omura, F, Matsubayashi, M, Tsutsui, T, ...
In the first experiment the influences of a single oral administration of a new antidepressant, Y-8894 50 mg, nortriptyline 50 mg, and placebo on physiological and psychological parameters were...
Shimizu, M, Nishida, A, Fukuda, H, Saito, H, Yamawaki, S
1. The effects of chronic in vitro administration of amitriptyline, a tricyclic antidepressant, on 5-hydroxytryptamine (5-HT) receptor-mediated adenylyl cyclase activity was studied in the...
Site of analgesic action of a non-steroidal, anti-inflammatory drug, tolmetin sodium, in rats.
1 The site of the analgesic action of tolmetin sodium was investigated by use of the acetic acid writhing test in rats. 2 Tolmetin sodium was administered to the rat between 15 and 60 min after...
Doppler assessment of pulmonary artery pressure in neonates at risk of chronic lung disease
Su, B., Watanabe, T., Shimizu, M., Yanagisawa, M.
AIM—To evaluate the pulmonary artery pressure (PAP) change in very low birthweight (VLBW) infants at risk of chronic lung disease (CLD). METHODS—The time to peak velocity:right ventricular...
Echocardiographic assessment of patent ductus arteriosus shunt flow pattern in premature infants
Su, B., Watanabe, T., Shimizu, M., Yanagisawa, M.
AIMS—To identify the patent ductus arteriosus (PDA) shunt flow pattern using Doppler echocardiography; and to assess whether it could be used to predict the development of clinically significant...
Percutaneous transluminal angioplasty for renovascular hypertension.
Awazu, M, Shimizu, M, Hojo, H, Osano, M, Kohda, E
Five children with renovascular hypertension were treated with percutaneous transluminal angioplasty, and followed for 12 to 32 months. Blood pressure fell to normal in four patients and improved in...
Sugiyama, K., Shimizu, M., Akiyama, T., Ishida, H., Okabe, M., Tamaoki, T., ...
Navelbine (NVB, vinorelbine ditartrate, KW-2307), a new vinca alkaloid analogue, has been shown to be clinically effective against advanced breast cancer. In this report, the combined effect of NVB...