M. Strolin Benedetti

Inducing properties of rifampicin and rifabutin for selected enzyme activities of the cytochrome P-450 and UDP-glucuronosyltransferase superfamilies in female rat liver (1996)

Oesch, F., Arand, M., Benedetti, M. Strolin, Castelli, M. G., Dostert, P.

Important species differences have been reported concerning the induction properties of rifampicin towards enzymes of the P-450 superfamily. Mice, rabbits and humans are far more responsive than rats...

An investigation of the pharmacokinetics and autoinduction of rifabuting metabolism in mice treated with 10 mg/kg/day six times a week for 8 weeks (1995)

Benedetti, M. Strolin, Pianezzola, E., Brianceschi, G., Jabes, D., Bruna, C. Delia, Rocchetti, M., ...

Plasma, lung and spleen concentrations of rifabutin have been measured in mice after single and multiple oral administrations of the drug. Rifabutin concentrations in spleen were similar to those...

Concentrations of rifabutin in plasma and cerebrospinal fluid in Cynomolgus monkeys (1994)

BENEDETTI, M. STROLIN, PIANEZZOLA, E., BRUGHERA, M., FRAIER, D., CASTELLI, M. G.

Animal phannacokinetics and interspecies scaling of FCE 22101, a penem antibiotic (1991)

Efthymiopoulos, C., Battaglia, R., Benedetti, M. Strolin

The pharmacokinetics of FCE 22101 were studied in rats, rabbits, Cynomolgus monkeys and dogs after intravenous administration. Pertinent pharmacokinetic parameters were determined according to a...

Rapid hydrolysis in vivo in man of FCE 22891, the orally absorbed ester of FCE 22101 (1990)

VINÇON, G., ALBIN, H., BATTAGLIA, R., MIGNON, A., BENEDETTI, M. STROLIN