M. Vrolix

Publication List Details

Period

1985 - 2002

Number

38

Co-Authors

Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial (2002)

Serruys, P.W., Meier, B., Feyter, P. De, Macaya, C., Kokott, N., Puel, J., ...

CONTEXT: Percutaneous coronary intervention (PCI) is associated with excellent short-term improvements in ischemic symptoms, yet only three fifths of PCI patients at 5 years and one third of patients...

A synthetic factor-Xa inhibitor (ORG31540/SR9017A) as an adjunct to fibrinolysis in acute myocardial infarction. The PENTALYSE study (2001)

Bassand, J P, Convens, C, Vrolix, M, Boland, J, Grollier, G, ...

BACKGROUND: ORG31540/SR90107A, a synthetic pentasaccharide, is a selective inhibitor of factor-Xa. It was hypothesized that prolonged factor-Xa inhibition with pentasaccharide may be an effective and...

A synthetic factor-Xa inhibitor (ORG31540/SR9017A) as an adjunct to fibrinolysis in acute myocardial infarction. The PENTALYSE study (2001)

Coussement, P.K, Convens, C, Vrolix, M, Boland, J, Grollier, G, ...

Background ORG31540/SR90107A, a synthetic pentasaccharide, is a selective inhibitor of factor-Xa. It was hypothesized that prolonged factor-Xa inhibition with pentasaccharide may be an effective and...

A randomized placebo-controlled trial of fluvastatin for prevention of restenosis after successful coronary balloon angioplasty; final results of the fluvastatin angiographic restenosis (FLARE) trial (1999)

Serruys, P.W., Shepherd, J., Suryapranata, H., Pfister, P.J., Feyter, P.J. De, Es, G.A. Van, ...

BACKGROUND: The 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors competitively inhibit biosynthesis of mevalonate, a precursor of non-sterol compounds involved in cell...

A randomized placebo-controlled trial of fluvastatin for prevention of restenosis after successful coronary balloon angioplasty: Final results of the fluvastatin angiographic restenosis (FLARE) trial (1999)

Serruys, P.W., Foley, D.P., Jackson, G., Bonnier, H., Macaya, C., Vrolix, M., ...

Background The 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors competitively inhibit biosynthesis of mevalonate, a precursor of non-sterol compounds involved in cell...

Randomized coronary patency trial of double-bolus recombinant staphylokinase versus front-loaded alteplase in acute myocardial infarction (1997)

Dens, J, Kerdsinchai, P, Vrolix, M, De Man, F, ...

One hundred two patients with evolving myocardial infarction of 6 hours' duration were given aspirin and intravenous heparin and randomly allocated to intravenous front-loaded, weight-adjusted rTPA...

Three-dimensional correction for spillover and recovery of myocardial PET images (1996)

Vrolix, M, Schiepers, C, Schelbert, H, Kuhle, W, ...

PET permits the quantification of myocardial blood flow, but is hampered by the limited spatial resolution of PET images. METHODS: We evaluated two methods for the correction of resolution effects in...

A randomized trial of recombinant staphylokinase versus alteplase for coronary artery patency in acute myocardial infarction. The STAR Trial Group (1995)

Barrios, L, Kerdsinchai, P, Hermans, L, Vrolix, M, ...

BACKGROUND: Recombinant staphylokinase (STAR) was shown recently to offer promise for coronary arterial thrombolysis in patients with evolving myocardial infarction. The present multicenter...

In vivo comparison between two tip pressure transducer systems (1995)

Vrolix, M, De Geest, H

Experimental findings are presented of an in vivo comparison between a Sentron catheter and another tip transducer manometer: a Millar microtip catheter. Both catheters have been used simultaneously...

Metabolism of nitrogen-13 labelled ammonia in different conditions in dogs, human volunteers and transplant patients (1995)

Maes, Alex; U0032501, Langendries, W, Vrolix, M, ...

To investigate the rate of metabolism of nitrogen-13 labelled ammonia (13NH3) in different conditions, we have determined the relative amount of unchanged 13NH3 in the blood of dogs, volunteers and...

The brachial approach for intracoronary stent implantation (1994)

Raymenants, E, Vrolix, M

Aggressive anticoagulation after intracoronary stent implantation leads to an increased incidence of femoral hematomas and vascular complications. Out of 74 Medtronic Wiktor stent implantations, six...

Angiotensin-converting enzyme inhibition with fosinopril sodium in the prevention of restenosis after coronary angioplasty (1994)

Vrolix, M, Van Lierde, J, Willems, J L

BACKGROUND: Several angiotensin-converting enzyme inhibitors have antiproliferative effects in a rat model after carotid artery balloon injury. METHODS AND RESULTS: We conducted a randomized,...

Prevention of restenosis after coronary balloon angioplasty: rationale and design of the Fluvavastatin Angioplasty Restenosis (FLARE) Trial (1994)

Foley, D.P., Bonnier, H., Jackson, G., Macaya, C., Shepherd, J., Vrolix, M., ...

Prevention of restenosis after successful percutaneous transluminal coronary balloon angioplasty (PTCA) continues to present the greatest therapeutic challenge in interventional cardiology....

Intra- and interobserver variability of a fast on-line quantitative coronary angiographic system (1993)

Willems, J L, Vrolix, M, Van Lierde, J, Byttebier, G

To evaluate intra- and interobserver variability of an on-line quantitative coronary angiographic system, 2 independent observers measured 166 primary lesions excluding total occlusions before and...

Echocardiographic detection of acute myocardial ischemia during percutaneous transluminal coronary angioplasty (1993)

Vrolix, M, ...

The usefulness of echocardiography and Doppler for the detection of acute myocardial ischemia was evaluated during right coronary artery occlusion in 20 patients. The echocardiographic findings were...

Isolated single coronary artery: a review of 50,000 consecutive coronary angiographies (1992)

Vrolix, M, ...

Single coronary artery is a rare congenital anomaly of the coronary arteries where only one coronary artery arises from the aortic trunk by a single coronary ostium, supplying the entire heart. A...

Immediate and follow-up results of the conservative coronary angioplasty strategy for unstable angina pectoris (1992)

Glazier, J J, Van Lierde, J, Vrolix, M, Willems, J L, ...

To assess the results of a conservative coronary angioplasty strategy in unstable angina pectoris, the records of 1,421 consecutive patients without previous myocardial infarction undergoing a first...

Isolated single coronary artery: a review of 50 000 consecutive coronary angiographies (1992)

DESMET, W., VANHAECKE, J., VROLIX, M., PIESSENS, J., WILLEMS, J., ...

Single coronary artery is a rare congenital anomaly of the coronary arteries where only one coronary artery arises from the aortic trunk by a single coronary ostium, supplying the entire heart. A...

Long-term prognosis of male patients with an isolated chronic occlusion of the left anterior descending coronary artery (1991)

Glazier, J J, Vrolix, M, De Geest, H, Willems, J L

The purpose of this study was to determine the long-term prognosis of patients with an isolated total occlusion of the left anterior descending artery (LAD). A total of 173 male patients with a...

The value of the intracoronary electrogram for the early detection of myocardial ischaemia during coronary angioplasty (1991)

Vrolix, M, Sionis, D, Glazier, J J, De Geest, H

The clinical value of intracoronary electrography for the detection of myocardia ischaemia was assessed during coronary angioplasty and compared to a standard technique of surface ECG monitoring. In...

Ridogrel in the setting of percutaneous transluminal coronary angioplasty (1991)

Vrolix, M, Stammen, F, ...

The safety of the combination of heparin and ridogrel therapy and its antiplatelet efficacy was examined in the setting of percutaneous transluminal coronary angioplasty (PTCA). In 32 patients...

Lack of evidence for small vessel disease in a patient with "slow dye progression" in the coronary arteries (1991)

Vrolix, M, Sionis, D, De Geest, H

A patient with chest pain of recent onset, suggestive for angina pectoris, was referred for diagnostic coronary angiography, which showed the typical phenomenon of "slow dye progression" in the...

Immediate and short-term results of a 1988-1989 coronary angioplasty registry (1991)

Vrolix, M, Glazier, J J, De Geest, H, Willems, J L

To determine the relevance of recent refinements in angioplasty technology to our particular practice, the records of 507 consecutive patients undergoing a first percutaneous transluminal coronary...

Silent ischaemia: an update on current concepts (1991)

Vrolix, M

Angina pectoris is the cardinal symptom of coronary heart disease and is a symptom with which physicians are very familiar. The clinical diagnosis of ischaemic heart disease is often based largely on...

Torsades de pointes after intracoronary papaverine (1991)

VROLIX, M., PIESSENS, J., GEEST, H. DE

Coronary blood flow velocity and coronary flow reserve can be assessed in humans using a coronary Doppler catheter and the vasodilator papaverine. Although it is a safe, elegant and reproducible...

Phospholipid-protein interactions of the plasma-membrane Ca2+-transporting ATPase. Evidence for a tissue-dependent functional difference (1990)

Vrolix, M

The aim of the present work was to investigate the stimulation of the plasma-membrane Ca2+-transporting ATPase by negatively charged phospholipids. The Ca2+-transporting ATPase was purified from pig...

Effect of intravenous diltiazem on myocardial ischemia occurring during percutaneous transluminal coronary angioplasty (1989)

Brzostek, T, Stammen, F, Vrolix, M, De Geest, H

To investigate the antiischemic efficacy of intravenously administered diltiazem, 42 patients were randomly allocated to receive placebo or active treatment before 1-vessel percutaneous transluminal...

AlF4- reversibly inhibits 'P'-type cation-transport ATPases, possibly by interacting with the phosphate-binding site of the ATPase (1988)

Vrolix, M

The only known cellular action of AlF4- is to stimulate the G-proteins. The aim of the present work is to demonstrate that AlF4- also inhibits 'P'-type cation-transport ATPases. NaF plus AlCl3...

Ca2+-transport ATPases of vascular smooth muscle (1988)

Vrolix, M

To characterize the Ca2+-transport properties of the plasma membrane and of the endoplasmic reticulum of bovine pulmonary artery, membrane vesicles are subfractionated by a procedure of...

The (Ca2+-Mg2+)-ATPases of the plasma membrane and of the endoplasmic reticulum in smooth muscle cells and their regulation (1988)

Vrolix, M

Smooth muscle cells contain two distinct Ca2+-transport ATpases with a different subcellular localization. The plasmalemmal Ca2+ pump has a relative molecular weight (Mr) of 140k and its...

Phospholipid-protein interactions of the plasma-membrane Ca2+-transporting ATPase. Evidence for a tissue-dependent functional difference.

Missiaen, L, Raeymaekers, L, Wuytack, F, Vrolix, M, De Smedt, H, Casteels, R

The aim of the present work was to investigate the stimulation of the plasma-membrane Ca2+-transporting ATPase by negatively charged phospholipids. The Ca2+-transporting ATPase was purified from pig...

Cyclic GMP-dependent protein kinase stimulates the plasmalemmal Ca2+ pump of smooth muscle via phosphorylation of phosphatidylinositol.

Vrolix, M, Raeymaekers, L, Wuytack, F, Hofmann, F, Casteels, R

The effect of phosphorylation by cyclic GMP-dependent protein kinase (G-kinase) on the activity of the plasmalemmal Ca2+-transport ATPase was studied on isolated plasma membranes and on the ATPase...

AlF4- reversibly inhibits 'P'-type cation-transport ATPases, possibly by interacting with the phosphate-binding site of the ATPase.

Missiaen, L, Wuytack, F, De Smedt, H, Vrolix, M, Casteels, R

The only known cellular action of AlF4- is to stimulate the G-proteins. The aim of the present work is to demonstrate that AlF4- also inhibits 'P'-type cation-transport ATPases. NaF plus AlCl3...

Phospholipid-protein interactions of the plasma-membrane Ca2+-transporting ATPase. Evidence for a tissue-dependent functional difference.

Missiaen, L, Raeymaekers, L, Wuytack, F, Vrolix, M, De Smedt, H, Casteels, R

The aim of the present work was to investigate the stimulation of the plasma-membrane Ca2+-transporting ATPase by negatively charged phospholipids. The Ca2+-transporting ATPase was purified from pig...

Cyclic GMP-dependent protein kinase stimulates the plasmalemmal Ca2+ pump of smooth muscle via phosphorylation of phosphatidylinositol.

Vrolix, M, Raeymaekers, L, Wuytack, F, Hofmann, F, Casteels, R

The effect of phosphorylation by cyclic GMP-dependent protein kinase (G-kinase) on the activity of the plasmalemmal Ca2+-transport ATPase was studied on isolated plasma membranes and on the ATPase...

AlF4- reversibly inhibits 'P'-type cation-transport ATPases, possibly by interacting with the phosphate-binding site of the ATPase.

Missiaen, L, Wuytack, F, De Smedt, H, Vrolix, M, Casteels, R

The only known cellular action of AlF4- is to stimulate the G-proteins. The aim of the present work is to demonstrate that AlF4- also inhibits 'P'-type cation-transport ATPases. NaF plus AlCl3...