M. Wiesnet

Flt-1, but not Flk-1 mediates hyperpermeability through activation of the PI3-K/Akt pathway (2007)

Vogel, C., Bauer, A., Wiesnet, M., Preissner, K. T., Schaper, W., Marti, H. H., ...

Vascular endothelial growth factor (VEGF), a potent mediator of endothelial proliferation and migration, has an important role also in brain edema formation during hypoxia and ischemia. VEGF binds to...

H2O2 induces paracellular permeability of porcine brain-derived microvascular endothelial cells by activation of the p44/42 MAP kinase pathway (2005)

Fischer, S., Wiesnet, M., Renz, D., Schaper, W.

In vivo, pathological conditions such as ischemia and ischemia/reperfusion are known to damage the blood-brain barrier (BBB) leading to the development of vasogenic brain edema. Using an in vitro...

H2O2 induces paracellular permeability of porcine brain-derived microvascular endothelial cells by activation of the p44/42 MAP kinase pathway (2005)

Fischer, S., Wiesnet, M., Renz, D., Schaper, W.

In vivo, pathological conditions such as ischemia and ischemia/reperfusion are known to damage the blood-brain barrier (BBB) leading to the development of vasogenic brain edema. Using an in vitro...

Simultaneous Activation of Several Second Messengers in Hypoxia-Induced Hyperpermeability of Brain Derived endothelial Cells (2004)

Fischer, S., Wiesnet, M., Marti, H.H., Renz, D., Schaper, W.