M. Zerah

Mutations within the MGC4607 Gene Cause Cerebral Cavernous Malformations

Denier, C., Goutagny, S., Labauge, P., Krivosic, V., Arnoult, M, Cousin, A., ...

Cerebral cavernous malformations (CCM) are hamartomatous vascular malformations characterized by abnormally enlarged capillary cavities without intervening brain parenchyma. They cause seizures and...

Comparative genomic hybridization detects many recurrent imbalances in central nervous system primitive neuroectodermal tumours in children

Avet-Loiseau, H, Vénuat, A-M, Terrier-Lacombe, M-J, Lellouch-Tubiana, A, Zerah, M, Vassal, G

A series of 23 children with primitive neuroectodermal tumours (PNET) were analysed with comparative genomic hybridization (CGH). Multiple chromosomal imbalances have been detected in 20 patients....

Chemotherapy for unresectable and recurrent intramedullary glial tumours in children

Doireau, V, Grill, J, Zerah, M, Lellouch-Tubiana, A, Couanet, D, Chastagner, P, ...

Adjuvant treatment for intramedullary tumours is based on radiotherapy. The place of chemotherapy in this setting has yet to be determined. Between May 1992 and January 1998, eight children with...