Investigation of a novel approach to scoring Giemsa-stained malaria-infected thin blood films (2008)
Proudfoot, Owen, Drew, Nathan, Scholzen, Anja, Xiang, Sue, Plebanski, Magdalena
Abstract Daily assessment of the percentage of erythrocytes that are infected ('percent-parasitaemia') across a time-course is a necessary step in many experimental studies of malaria, but represents...
Apostolopoulos, Vasso, Pietersz, Geoffrey A, Tsibanis, Anastasios, Tsikkinis, Annivas, Drakaki, Heleni, Loveland, Bruce E, ...
Abstract Introduction Mucin 1 (MUC1) is a high molecular weight glycoprotein overexpressed on adenocarcinoma cells and is a target for immunotherapy protocols. To date, clinical trials against MUC1...
Plebanski, Magdalena, Lopez, Ester, Proudfoot, Owen, Cook, Brian M., Von Itzstein, Mark, Coppel, Ross L.
Yes
Plebanski, Magdalena, Lopez, Ester, Proudfoot, Owen, Cook, Brian M., Von Itzstein, Mark, Coppel, Ross L.
Yes
Plebanski, Magdalena, Lopez, Ester, Proudfoot, Owen, Cook, Brian M., Von Itzstein, Mark, Coppel, Ross L.
Plebanski, Magdalena, Lopez, Ester, Proudfoot, Owen, Cook, Brian M., Von Itzstein, Mark, Coppel, Ross L.
Herein, we analyze in general the current vaccine market and identify potential factors driving and modulating supply and demand for vaccines. An emphasis is placed on changes in regulation in the...
Magdalena Plebanski, Carolyn M Hannan, Shahriar Behboudi, Katie L Flanagan, Vasso Apostolopoulos
Irradiated malaria sporozoites induce better protection than viable untreated sporozoites. We observed early differences between irradiated and viable untreated sporozoites in priming responses in...
In vitro proliferative responses of human T cells to autologous and heterologous antigens. (1992)
Thesis (Ph. D.)--University of Bristol, 1992.
Lee, Edwin A. M., Palmer, Dupeh R., Flanagan, Katie L., Reece, William H. H., Odhiambo, Kennedy, Marsh, Kevin, ...
Plasmodium falciparum malaria is a major cause of death in the tropics. The 19-kDa subunit of P. falciparum merozoite surface protein 1 (MSP-119), a major blood stage vaccine candidate, is the target...
Plebanski, Magdalena, Proudfoot, Owen, Pouniotis, Dodie, Coppel, Ross L., Apostolopoulos, Vasso, Flannery, Graham
A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor
Apostolopoulos, Vasso, Yuriev, Elizabeth, Ramsland, Paul A., Halton, Jodie, Osinski, Carla, Li, Wenjun, ...
Peptides bind MHC class I molecules by anchoring hydrophobic side chains into pockets in the peptide binding groove. Here, we report an immunogenic (in vitro and in vivo) MUC1 glycopeptide...
Pouniotis, Dodie S., Proudfoot, Owen, Bogdanoska, Violeta, Apostolopoulos, Vasso, Fifis, Theodora, Plebanski, Magdalena
Dendritic cells (DC) suffer a maturation defect following interaction with erythrocytes infected with malaria parasites and become unable to induce protective malaria liver-stage immunity. Here we...
Apostolopoulos, Vasso, Pietersz, Geoffrey A, Tsibanis, Anastasios, Tsikkinis, Annivas, Drakaki, Heleni, Loveland, Bruce E, ...
Lee, Edwin A. M., Palmer, Dupeh R., Flanagan, Katie L., Reece, William H. H., Odhiambo, Kennedy, Marsh, Kevin, ...
Plasmodium falciparum malaria is a major cause of death in the tropics. The 19-kDa subunit of P. falciparum merozoite surface protein 1 (MSP-119), a major blood stage vaccine candidate, is the target...
Plebanski, Magdalena, Proudfoot, Owen, Pouniotis, Dodie, Coppel, Ross L., Apostolopoulos, Vasso, Flannery, Graham
A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor
Apostolopoulos, Vasso, Yuriev, Elizabeth, Ramsland, Paul A., Halton, Jodie, Osinski, Carla, Li, Wenjun, ...
Peptides bind MHC class I molecules by anchoring hydrophobic side chains into pockets in the peptide binding groove. Here, we report an immunogenic (in vitro and in vivo) MUC1 glycopeptide...
Pouniotis, Dodie S., Proudfoot, Owen, Bogdanoska, Violeta, Apostolopoulos, Vasso, Fifis, Theodora, Plebanski, Magdalena
Dendritic cells (DC) suffer a maturation defect following interaction with erythrocytes infected with malaria parasites and become unable to induce protective malaria liver-stage immunity. Here we...
Apostolopoulos, Vasso, Pietersz, Geoffrey A, Tsibanis, Anastasios, Tsikkinis, Annivas, Drakaki, Heleni, Loveland, Bruce E, ...
Mannan-mediated gene delivery for cancer immunotherapy
Tang, Choon K, Lodding, Jodie, Minigo, Gabriela, Pouniotis, Dodie S, Plebanski, Magdalena, Scholzen, Anja, ...
Recent years have seen a resurgence in interest in the development of efficient non-viral delivery systems for DNA vaccines and gene therapy. We have previously used oxidized and reduced mannan as...
Investigation of a novel approach to scoring Giemsa-stained malaria-infected thin blood films
Proudfoot, Owen, Drew, Nathan, Scholzen, Anja, Xiang, Sue, Plebanski, Magdalena
Daily assessment of the percentage of erythrocytes that are infected ('percent-parasitaemia') across a time-course is a necessary step in many experimental studies of malaria, but represents a...
Todryk, Stephen M., Bejon, Philip, Mwangi, Tabitha, Plebanski, Magdalena, Urban, Britta, Marsh, Kevin, ...
Natural Regulatory T Cells and Persistent Viral Infection▿
Li, Shuo, Gowans, Eric J., Chougnet, Claire, Plebanski, Magdalena, Dittmer, Ulf
Minigo, Gabriela, Woodberry, Tonia, Piera, Kim A., Salwati, Ervi, Tjitra, Emiliana, Kenangalem, Enny, ...
Severe Plasmodium falciparum malaria is a major cause of global mortality, yet the immunological factors underlying progression to severe disease remain unclear. CD4+CD25+ regulatory T cells (Treg...
Scholzen, Anja, Mittag, Diana, Rogerson, Stephen J., Cooke, Brian M., Plebanski, Magdalena
CD4+CD25+Foxp3+ regulatory T cells (Tregs) regulate disease-associated immunity and excessive inflammatory responses, and numbers of CD4+CD25+Foxp3+ Tregs are increased during malaria infection. The...