Magnus Korsgren

Effects of intranasal TNFα on granulocyte recruitment and activity in healthy subjects and patients with allergic rhinitis (2008)

Widegren, Henrik, Erjefält, Jonas, Korsgren, Magnus, Andersson, Morgan, Greiff, Lennart

Abstract Background TNFα may contribute to the pathophysiology of airway inflammation. For example, we have recently shown that nasal administration of TNFα produces late phase co-appearance of...

Antagonism of the prostaglandin D2receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation (2007)

Uller, Lena, Mathiesen, Jesper, Alenmyr, Lisa, Korsgren, Magnus, Ulven, Trond, Högberg, Thomas, ...

Abstract Background Mast cell-derived prostaglandin D 2 (PGD 2 ), may contribute to eosinophilic inflammation and mucus production in allergic asthma. Chemoattractant receptor homologous molecule...

Genomic and functional delineation of dendritic cells and memory T cells derived from grass pollen-allergic patients and healthy individuals. (2005)

Lindstedt, Malin, Schiött, Asa, Bengtsson, Astrid, Larsson, Kristina, Korsgren, Magnus, Greiff, Lennart, ...

Dendritic cells (DCIs) possess a potent ability to modulate and activate specific T-cell responses to allergens, which play a pivotal role in allergic inflammation by secreting cytokines and other...

Genomic and functional delineation of dendritic cells and memory T cells derived from grass pollen-allergic patients and healthy individuals (2005)

Lindstedt, Malin, Schiött, Åsa, Bengtsson, Astrid, Larsson, Kristina, Korsgren, Magnus, Greiff, Lennart, ...

Dendritic cells (DCIs) possess a potent ability to modulate and activate specific T-cell responses to allergens, which play a pivotal role in allergic inflammation by secreting cytokines and other...

Genomic and functional delineation of dendritic cells and memory T cells derived from grass pollen-allergic patients and healthy individuals (2005)

Lindstedt, Malin, Schiött, Åsa, Bengtsson, Astrid, Larsson, Kristina, Korsgren, Magnus, Greiff, Lennart, ...

Dendritic cells (DCIs) possess a potent ability to modulate and activate specific T-cell responses to allergens, which play a pivotal role in allergic inflammation by secreting cytokines and other...

Neural Expression and Increased Lavage Fluid Levels of Secretoneurin in Seasonal Allergic Rhinitis (2003)

Korsgren, Magnus, Erjefalt, Jonas S., Hinterholzl, Josef, Fischer-Colbrie, Reiner, Emanuelsson, Cecilia Ahlstrom, Andersson, Morgan, ...

Secretoneurin is a neuropeptide potentially involved in migration of eosinophils, monocytes, and dendritic cells. Whether secretoneurin is present in the human airway mucosa and whether it is...

Eosinophil infiltration and activation at the gastric ulcer margin in rats. (2002)

Mei, Qi, Korsgren, Magnus, Erjefält, Jonas S, Sundler, Frank

BACKGROUND : Recruitment and activation of eosinophils have been studied intensely in asthma and other allergic diseases. Less is known about the infiltration and behaviour of eosinophils during...

NK cells and asthma. (2002)

Korsgren, Magnus

NK cells have been associated with immune surveillance of tumor cells and defense mechanisms against various pathogens. However, by their capacity for immunoregulation NK cells may also play a role...

Immunoregulation in an experimental model of allergic asthma (2000)

Korsgren, Magnus

In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the...

Immunoregulation in an experimental model of allergic asthma (2000)

Korsgren, Magnus

In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the...

The Effect of Lignocaine on the Stimulation Threshold and Conduction Disturbances in Patients Treated with Pacemaker (1969)

Rydén, Lars, Korsgren, Magnus

Authors' SynopsisThe present study was carried out to see if lignocaine in therapeutic anti-arrhythmic dosages given to pacemaker-treated patients involved any risks of exit block. We conclude that...

Natural Killer Cells Determine Development of Allergen-induced Eosinophilic Airway Inflammation in Mice

Korsgren, Magnus, Persson, Carl G.A., Sundler, Frank, Bjerke, Torbjörn, Hansson, Tony, Chambers, Benedict J., ...

The earliest contact between antigen and the innate immune system is thought to direct the subsequent antigen-specific T cell response. We hypothesized that cells of the innate immune system, such as...

Allergic Eosinophil-rich Inflammation Develops in Lungs and Airways of B Cell–deficient Mice

Korsgren, Magnus, ält, Jonas S. Erjef, Korsgren, Olle, Sundler, Frank, Persson, Carl G.A.

Immunoglobulins (Ig), particularly IgE, are believed to be crucially involved in the pathogenesis of asthma and, equally, in allergic models of the disease. To validate this paradigm we examined...