Scalable Manufacture of Cells (2009)
Mahendra S. Rao of Johns Hopkins University, Invitrogen and the Buck Institute for Age Research presented a lecture on September 10, 2009 at 11:00 am in the Suddath Seminar Room, IBB Building,...
Tavakoli, Tahereh, Xu, Xiangru, Derby, Eric, Serebryakova, Yevgeniya, Reid, Yvonne, Rao, Mahendra S, ...
Abstract Background A unique and essential property of embryonic stem cells is the ability to self-renew and differentiate into multiple cell lineages. However, the possible differences in...
Expression profiling of human glial precursors (2008)
Campanelli, James T, Sandrock, Robert W, Wheatley, Will, Xue, Haipeng, Zheng, Jianhua, Liang, Feng, ...
Abstract Background We have generated gene expression databases for human glial precursors, neuronal precursors, astrocyte precursors and neural stem cells and focused on comparing the profile of...
Ma, Wu, Tavakoli, Tara, Derby, Eric, Serebryakova, Yevgeniya, Rao, Mahendra S, Mattson, Mark P
Abstract Background Interactions of cells with the extracellular matrix (ECM) are critical for the establishment and maintenance of stem cell self-renewal and differentiation. However, the ECM is a...
Regulatory networks define phenotypic classes of human stem cell lines (2008)
Müller, Franz-Josef, Laurent, Louise C., Kostka, Dennis, Ulitsky, Igor, Williams, Roy, Lu, Christina, ...
Stem cells are defined as self-renewing cell populations that can differentiate into multiple distinct cell types. However, hundreds of different human cell lines from embryonic, fetal and adult...
A large-scale proteomic analysis of human embryonic stem cells (2007)
Schulz, Thomas C, Swistowska, Anna, Liu, Ying, Swistowski, Andrzej, Palmarini, Gail, Brimble, Sandii N, ...
Abstract Background Much of our current knowledge of the molecular expression profile of human embryonic stem cells (hESCs) is based on transcriptional approaches. These analyses are only partly...
A large-scale proteomic analysis of human embryonic stem cells (2007)
Bmc Genomics, Thomas C Schulz, Anna Maria Swistowska, Ying Liu, Andrzej Swistowski, Gail Palmarini, ...
© 2007 Schulz et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
A molecular scheme for improved characterization of human embryonic stem cell lines (2006)
Josephson, Richard, Sykes, Gregory, Liu, Ying, Ording, Carol, Xu, Weining, Zeng, Xianmin, ...
Abstract Background Human embryonic stem cells (hESC) offer a renewable source of a wide range of cell types for use in research and cell-based therapies to treat disease. Inspection of protein...
Liu, Ying, Shin, Soojung, Zeng, Xianmin, Zhan, Ming, Gonzalez, Rodolfo, Mueller, Franz-Josef, ...
Abstract Background In order to compare the gene expression profiles of human embryonic stem cell (hESC) lines and their differentiated progeny and to monitor feeder contaminations, we have examined...
Transcriptome coexpression map of human embryonic stem cells (2006)
Li, Huai, Liu, Ying, Shin, Soojung, Sun, Yu, Loring, Jeanne F, Mattson, Mark P, ...
Abstract Background Human embryonic stem (ES) cells hold great promise for medicine and science. The transcriptome of human ES cells has been studied in detail in recent years. However, no systematic...
Development of antibodies to human embryonic stem cell antigens (2005)
Cai, Jingli, Olson, Judith M, Rao, Mahendra S, Stanley, Marisa, Taylor, Eva, Ni, Hsiao-Tzu
Abstract Background Using antibodies to specific protein antigens is the method of choice to assign and identify cell lineage through simultaneous analysis of surface molecules and intracellular...
Bhattacharya, Bhaskar, Cai, Jingli, Luo, Youngquan, Miura, Takumi, Mejido, Josef, Brimble, Sandii N, ...
Abstract Background The identification of molecular pathways of differentiation of embryonic stem cells (hESC) is critical for the development of stem cell based medical therapies. In order to...
A central nervous system specific mouse model for Thanatophoric Dysplasia Type II (2003)
Lin, Ti, Sandusky, Stacey B., Xue, Haipeng, Fishbein, Kenneth W., Spencer, Richard G., Rao, Mahendra S., ...
To investigate the specific effect of the Fgfr3 K644E mutation on central nervous system (CNS) development, we have generated tissue-specific TDII mice by crossing Fgfr3+/neo-K644E transgenic mice...
A central nervous system specific mouse model for thanatophoric dysplasia type II (2003)
Lin, Ti, Sandusky, Stacey B., Xue, Haipeng, Fishbein, Kenneth W., Spencer, Richard G., Rao, Mahendra S., ...
To investigate the specific effect of the Fgfr3 K644E mutation on central nervous system (CNS) development, we have generated tissue-specific TDII mice by crossing Fgfr3+/K644E-neo...
A central nervous system specific mouse model for Thanatophoric Dysplasia Type II (2003)
Lin, Ti, Sandusky, Stacey B., Xue, Haipeng, Fishbein, Kenneth W., Spencer, Richard G., Rao, Mahendra S., ...
To investigate the specific effect of the Fgfr3 K644E mutation on central nervous system (CNS) development, we have generated tissue-specific TDII mice by crossing Fgfr3+/neo-K644E transgenic mice...
A tripotential glial precursor cell is present in the developing spinal cord
Rao, Mahendra S., Noble, Mark, Mayer-Pröschel, Margot
We have isolated a tripotential glial precursor cell population from spinal cords of E13.5 rats. In vitro, these A2B5+E-NCAM− glial-restricted precursor (GRP) cells can undergo extensive...
Yang, Hui, Mujtaba, Tahimina, Venkatraman, Giri, Wu, Yuan Yuan, Rao, Mahendra S., Luskin, Marla B.
Spinal cord neuronal restricted progenitor (NRP) cells, when transplanted into the neonatal anterior forebrain subventricular zone, migrate to distinct regions throughout the forebrain including the...
Regulation of eye development by frizzled signaling in Xenopus
Rasmussen, Jennifer T., Deardorff, Matthew A., Tan, Change, Rao, Mahendra S., Klein, Peter S., Vetter, Monica L.
Eye development in both invertebrates and vertebrates is regulated by a network of highly conserved transcription factors. However, it is not known what controls the expression of these factors to...
Bhattacharya, Bhaskar, Cai, Jingli, Luo, Youngquan, Miura, Takumi, Mejido, Josef, Brimble, Sandii N, ...
Development of antibodies to human embryonic stem cell antigens
Cai, Jingli, Olson, Judith M, Rao, Mahendra S, Stanley, Marisa, Taylor, Eva, Ni, Hsiao-Tzu
LEPORE, ANGELO C., HAN, STEVEN S.W., TYLER-POLSZ, CARLA J., CAI, JINGLI, RAO, MAHENDRA S., FISCHER, ITZHAK
Multiple classes of precursor cells have been isolated and characterized from the developing spinal cord including multipotent neuroepithelial (NEP) stem cells and lineage-restricted precursors for...
Transcriptome coexpression map of human embryonic stem cells
Li, Huai, Liu, Ying, Shin, Soojung, Sun, Yu, Loring, Jeanne F, Mattson, Mark P, ...
A molecular scheme for improved characterization of human embryonic stem cell lines
Josephson, Richard, Sykes, Gregory, Liu, Ying, Ording, Carol, Xu, Weining, Zeng, Xianmin, ...
A tripotential glial precursor cell is present in the developing spinal cord
Rao, Mahendra S., Noble, Mark, Mayer-Pröschel, Margot
We have isolated a tripotential glial precursor cell population from spinal cords of E13.5 rats. In vitro, these A2B5+E-NCAM− glial-restricted precursor (GRP) cells can undergo extensive...
Yang, Hui, Mujtaba, Tahimina, Venkatraman, Giri, Wu, Yuan Yuan, Rao, Mahendra S., Luskin, Marla B.
Spinal cord neuronal restricted progenitor (NRP) cells, when transplanted into the neonatal anterior forebrain subventricular zone, migrate to distinct regions throughout the forebrain including the...
Regulation of eye development by frizzled signaling in Xenopus
Rasmussen, Jennifer T., Deardorff, Matthew A., Tan, Change, Rao, Mahendra S., Klein, Peter S., Vetter, Monica L.
Eye development in both invertebrates and vertebrates is regulated by a network of highly conserved transcription factors. However, it is not known what controls the expression of these factors to...
Bhattacharya, Bhaskar, Cai, Jingli, Luo, Youngquan, Miura, Takumi, Mejido, Josef, Brimble, Sandii N, ...
Development of antibodies to human embryonic stem cell antigens
Cai, Jingli, Olson, Judith M, Rao, Mahendra S, Stanley, Marisa, Taylor, Eva, Ni, Hsiao-Tzu
Transcriptome coexpression map of human embryonic stem cells
Li, Huai, Liu, Ying, Shin, Soojung, Sun, Yu, Loring, Jeanne F, Mattson, Mark P, ...
A molecular scheme for improved characterization of human embryonic stem cell lines
Josephson, Richard, Sykes, Gregory, Liu, Ying, Ording, Carol, Xu, Weining, Zeng, Xianmin, ...
Freed, William J., Chen, Jia, Bäckman, Cristina M., Schwartz, Catherine M., Vazin, Tandis, Cai, Jingli, ...
A large-scale proteomic analysis of human embryonic stem cells
Schulz, Thomas C, Swistowska, Anna Maria, Liu, Ying, Swistowski, Andrzej, Palmarini, Gail, Brimble, Sandii N, ...
Ravindranathan, Ajay, Donevan, Sean D, Sugden, Steven G, Greig, Ann, Rao, Mahendra S, Parks, Thomas N
Neurons in the brainstem auditory pathway exhibit a number of specializations for transmitting signals reliably at high rates, notably synaptic AMPA receptors with very rapid kinetics. Previous work...
Evolutionarily Conserved Transcriptional Co-Expression Guiding Embryonic Stem Cell Differentiation
Sun, Yu, Li, Huai, Liu, Ying, Mattson, Mark P., Rao, Mahendra S., Zhan, Ming
Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells
Ma, Wu, Tavakoli, Tara, Derby, Eric, Serebryakova, Yevgeniya, Rao, Mahendra S, Mattson, Mark P
Expression profiling of human glial precursors
Campanelli, James T, Sandrock, Robert W, Wheatley, Will, Xue, Haipeng, Zheng, Jianhua, Liang, Feng, ...
Wang, Linlin, Schulz, Thomas C., Sherrer, Eric S., Dauphin, Derek S., Shin, Soojung, Nelson, Angelique M., ...
Despite progress in developing defined conditions for human embryonic stem cell (hESC) cultures, little is known about the cell-surface receptors that are activated under conditions supportive of...
Magnus, Tim, Liu, Ying, Parker, Graham C, Rao, Mahendra S
Stem cells, although difficult to define, hold great promise as tools for understanding development and as therapeutic agents. However, as with any new field, uncritical enthusiasm can outstrip...
Tavakoli, Tahereh, Xu, Xiangru, Derby, Eric, Serebryakova, Yevgeniya, Reid, Yvonne, Rao, Mahendra S, ...
β1 Integrin Maintains Integrity of the Embryonic Neocortical Stem Cell Niche
Loulier, Karine, Lathia, Justin D., Marthiens, Veronique, Relucio, Jenne, Mughal, Mohamed R., Tang, Sung-Chun, ...
IInteractions between laminins and integrin receptors hold neural stem cells in place at the ventricular surface of embryonic brain. Transient disruption leads to abnormal stem cell divisions and...