Mai Xu

ICAT expression disrupts {beta}-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells (2008)

Hossain, M. Zulfiquer, Yu, Qing, Xu, Mai, Sen, Jyoti Misra

T cell factor (TCF) family of transcription factors and β-catenin critically regulate T cell development as demonstrated by the deletion of the tcf gene, which results in a block early in...

Gal4p-Mediated Chromatin Remodeling Depends on Binding Site Position in Nucleosomes but Does Not Require DNA Replication

Xu, Mai, Simpson, Robert T., Kladde, Michael P.

Biochemical studies have demonstrated decreased binding of various proteins to DNA in nucleosome cores as their cognate sites are moved from the edge of the nucleosome to the pseudodyad (center)....

Nuclear matrix as a target for hyperthermic killing of cancer cells

Roti Roti, Joseph L., Kampinga, Harm H., Malyapa, Robert S., Wright, William D., VanderWaal, Robert P., Xu, Mai

The nuclear matrix organizes nuclear DNA into operational domains in which DNA is undergoing replication, transcription or is inactive. The proteins of the nuclear matrix are among the most thermal...

Gal4p-Mediated Chromatin Remodeling Depends on Binding Site Position in Nucleosomes but Does Not Require DNA Replication

Xu, Mai, Simpson, Robert T., Kladde, Michael P.

Biochemical studies have demonstrated decreased binding of various proteins to DNA in nucleosome cores as their cognate sites are moved from the edge of the nucleosome to the pseudodyad (center)....

Nuclear matrix as a target for hyperthermic killing of cancer cells

Roti Roti, Joseph L., Kampinga, Harm H., Malyapa, Robert S., Wright, William D., VanderWaal, Robert P., Xu, Mai

The nuclear matrix organizes nuclear DNA into operational domains in which DNA is undergoing replication, transcription or is inactive. The proteins of the nuclear matrix are among the most thermal...

β-Catenin Expression Results in p53-Independent DNA Damage and Oncogene-Induced Senescence in Prelymphomagenic Thymocytes In Vivo▿ †

Xu, Mai, Yu, Qing, Subrahmanyam, Ramesh, Difilippantonio, Michael J., Ried, Thomas, Sen, Jyoti Misra

The expression of β-catenin, a potent oncogene, is causally linked to tumorigenesis. Therefore, it was surprising that the transgenic expression of oncogenic β-catenin in thymocytes resulted in...