Maite Huarte

PA Subunit from Influenza Virus Polymerase Complex Interacts with a Cellular Protein with Homology to a Family of Transcriptional Activators

Huarte, Maite, Sanz-Ezquerro, Juan Jose, Roncal, Fernando, Ortín, Juan, Nieto, Amelia

The PA subunit of the influenza virus polymerase complex is a phosphoprotein that induces proteolytic degradation of coexpressed proteins. Point mutants with reduced proteolysis induction...

Threonine 157 of Influenza Virus PA Polymerase Subunit Modulates RNA Replication in Infectious Viruses

Huarte, Maite, Falcón, Ana, Nakaya, Yuri, Ortín, Juan, García-Sastre, Adolfo, Nieto, Amelia

Previous results have shown a correlation between the decrease in protease activity of several influenza A virus PA protein mutants and the capacity to replicate of the corresponding mutant...

Essential Dosage-Dependent Functions of the Transcription Factor Yin Yang 1 in Late Embryonic Development and Cell Cycle Progression†

Affar, El Bachir, Gay, Frédérique, Shi, Yujiang, Liu, Huifei, Huarte, Maite, Wu, Su, ...

Constitutive ablation of the Yin Yang 1 (YY1) transcription factor in mice results in peri-implantation lethality. In this study, we used homologous recombination to generate knockout mice carrying...

PA Subunit from Influenza Virus Polymerase Complex Interacts with a Cellular Protein with Homology to a Family of Transcriptional Activators

Huarte, Maite, Sanz-Ezquerro, Juan Jose, Roncal, Fernando, Ortín, Juan, Nieto, Amelia

The PA subunit of the influenza virus polymerase complex is a phosphoprotein that induces proteolytic degradation of coexpressed proteins. Point mutants with reduced proteolysis induction...

Threonine 157 of Influenza Virus PA Polymerase Subunit Modulates RNA Replication in Infectious Viruses

Huarte, Maite, Falcón, Ana, Nakaya, Yuri, Ortín, Juan, García-Sastre, Adolfo, Nieto, Amelia

Previous results have shown a correlation between the decrease in protease activity of several influenza A virus PA protein mutants and the capacity to replicate of the corresponding mutant...

Essential Dosage-Dependent Functions of the Transcription Factor Yin Yang 1 in Late Embryonic Development and Cell Cycle Progression†

Affar, El Bachir, Gay, Frédérique, Shi, Yujiang, Liu, Huifei, Huarte, Maite, Wu, Su, ...

Constitutive ablation of the Yin Yang 1 (YY1) transcription factor in mice results in peri-implantation lethality. In this study, we used homologous recombination to generate knockout mice carrying...

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

Khalil, Ahmad M., Guttman, Mitchell, Huarte, Maite, Garber, Manuel, Raj, Arjun, Rivea Morales, Dianali, ...

We recently showed that the mammalian genome encodes >1,000 large intergenic noncoding (linc)RNAs that are clearly conserved across mammals and, thus, functional. Gene expression patterns have...