Tsuchiya, Toshiyuki, Tanaka-Kagawa, Toshiko, Jinno, Hideto, Tokunaga, Hiroshi, Sakimoto, Kazunori, Ando, Masanori, ...
We have performed two-stage transformation assay using BALB/c 3T3 cells to determine initiating and promoting activities of disodium arsenate, sodium arsenite, monomethylarsonic acid (MMAA) and...
Tsuchiya, Toshiyuki, Tanaka-Kagawa, Toshiko, Jinno, Hideto, Tokunaga, Hiroshi, Sakimoto, Kazunori, Ando, Masanori, ...
We have performed 2-stage transformation assay using BALB/c 3T3 cells to determine initiating and promoting activities of disodium arsenate, sodium arsenite, monomethylarsonic acid (MMAA) and...
Koshikawa, Naohiko, Nakamura, Takashi, Tsuchiya, Naoto, Isaji, Mitsuko, Yasumitsu, Hidetaro, Umeda, Makoto, ...
Our previous studies have shown that some human cancer cell lines produce pancreatic trypsinogen, plasminogen, and tissue-type kallikrein. To understand the regulatory mechanism of these proteinases,...
Tsuchiya, Toshiyuki, Umeda, Makoto
In order to improve the in vitro transformation assay using BALB/3T3 cells, which is routinely conducted with minimal essential medium (MEM) containing 10% fetal calf serum (FCS), we examined the...
Marked Stimulation of Cell Adhesion and Motility by Ladsin, a Laminin-Like Scatter Factor (1994)
Kikkawa, Yamato, Umeda, Makoto, Miyazaki, Kaoru
Ladsin is a large cell-adhesive protein with potent cell-scattering activity, which was recently identified in the culture of a malignant human gastric carcinoma cell line [Miyazaki, K. et al. (1993)...
Miyagi, Yohei, Koshikawa, Naohiko, Yasumitsu, Hidetaro, Miyagi, Etsuko, Hirahara, Fumiki, Aoki, Ichiro, ...
A serine proteinase inhibitor was purified from conditioned medium of the human glioblastoma cell line T98G. Analysis of its partial amino acid sequences indicated that this protein was identical to...
Yasumitsu, Hidetaro, Miyazaki, Kaoru, Umenishi, Fuminori, Koshikawa, Naohiko, Umeda, Makoto
Two kinds of gelatinases (or type IV collagenases), 90-kDa and 64-kDa gelatinases, were purified in a tissue inhibitor of metalloproteinases (TIMP)- or TIMP-2-free form from the serum-free...
Umenishi, Fuminori, Umeda, Makoto, Miyazaki, Kaoru
Metalloproteinase inhibitors were surveyed with the culture media of 19 kinds of human tumor cell lines, using transin (rat stromelysin) as the target enzyme. This survey showed that most of the cell...
Umenishi, Fuminori, Yasumitsu, Hidetaro, Ashida, Yoshiyuki, Jun-iti, Yamauti, Umeda, Makoto, Miyazaki, Kaoru
Rous sarcoma virus-transformed rat liver cell line RSV-BRL secreted a neutral proteinase in a latent precursor form with a molecular weight (Mr) of 57,000 (57k) as a major secreted protein. This...
Umeda, Makoto, Tanaka, Kumiko, Ono, Tetsuo
X-ray-irradiated BALB/3T3 A31-1-1 cloned cells were post-treated with lithocholk acid (LCA), one of the bile acids, and 3-hydroxyanthranilk acid (3HOA), a tryptopban metabolite, in order to examine...
Cytotoxic and mutagenic effects of sterigmatocystin on cultured Chinese hamster cells (1981)
Noda, Kouichi, Umeda, Makoto, Ueno, Yoshio
Cytotoxic and mutagenic effects of sterigmatocystin (STC), a carcinogenic mycotoxin, on cultured Chinese hamster cells were investigated in the presence or absence of a metabolic activation system....
Tanabe, Kaori, Ito, Noriko, Wakuri, Tomomi, Ozoe, Fumiyo, Umeda, Makoto, Katayama, Satoshi, ...
Sla1 is a Schizosaccharomyces pombe homolog of the human La protein. La proteins are known to be RNA-binding proteins that bear conserved RNA recognition motifs (La and RRMs), but their biological...
Production of Rubratoxin B by Penicillium purpurogenum Stoll
Natori, Shinsaku, Sakaki, Setsuko, Kurata, Hiroshi, Udagawa, Shun-Ichi, Ichinoe, Masakatsu, Saito, Mamoru, ...
Culture filtrates and chloroform extracts from Penicillium purpurogenum isolated from foodstuffs were subjected to preliminary survey for toxic effects on HeLa cells and mice. The toxic metabolite...
Baï, Siau Wei, Rouquette, Jacques, Umeda, Makoto, Faigle, Wolfgang, Loew, Damarys, Sazer, Shelley, ...
We have characterized Schizosaccharomyces pombe open reading frames encoding potential orthologues of constituents of the evolutionarily conserved Saccharomyces cerevisiae Nup84 vertebrate Nup107-160...
Umeda, Makoto, Izaddoost, Shahed, Cushman, Ian, Moore, Mary Shannon, Sazer, Shelley
The nuclear import of classical nuclear localization signal-containing proteins depends on importin-α transport receptors. In budding yeast there is a single importin-α gene and in higher...
Tanabe, Kaori, Ito, Noriko, Wakuri, Tomomi, Ozoe, Fumiyo, Umeda, Makoto, Katayama, Satoshi, ...
Sla1 is a Schizosaccharomyces pombe homolog of the human La protein. La proteins are known to be RNA-binding proteins that bear conserved RNA recognition motifs (La and RRMs), but their biological...
Production of Rubratoxin B by Penicillium purpurogenum Stoll
Natori, Shinsaku, Sakaki, Setsuko, Kurata, Hiroshi, Udagawa, Shun-Ichi, Ichinoe, Masakatsu, Saito, Mamoru, ...
Culture filtrates and chloroform extracts from Penicillium purpurogenum isolated from foodstuffs were subjected to preliminary survey for toxic effects on HeLa cells and mice. The toxic metabolite...
Baï, Siau Wei, Rouquette, Jacques, Umeda, Makoto, Faigle, Wolfgang, Loew, Damarys, Sazer, Shelley, ...
We have characterized Schizosaccharomyces pombe open reading frames encoding potential orthologues of constituents of the evolutionarily conserved Saccharomyces cerevisiae Nup84 vertebrate Nup107-160...
Umeda, Makoto, Izaddoost, Shahed, Cushman, Ian, Moore, Mary Shannon, Sazer, Shelley
The nuclear import of classical nuclear localization signal-containing proteins depends on importin-α transport receptors. In budding yeast there is a single importin-α gene and in higher...