Good laboratory practice: preventing introduction of bias at the bench (2009)
Macleod, Malcolm R., Fisher, Marc, O'Collins, Victoria, Sena, Emily S., Dirnagl, Ulrich, Bath, Philip M.W., ...
Background and Purpose—As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human...
Crossley, Nicolas A., Sena, Emily S., Goehler, Jos, Horn, Jannekke, Van Der Worp, H. Bart, Bath, Philip M.W., ...
Background and Purpose—At least part of the failure in the transition from experimental to clinical studies in stroke has been attributed to the imprecision introduced by problems in the design of...
Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis (2007)
Van Der Worp, H. Bart, Sena, Emily S., Donnan, Geoffrey A., Howells, David W., Macleod, Malcolm R.
Induced hypothermia is proposed as a treatment for acute ischaemic stroke, but there have been too few clinical trials involving too few patients to draw any conclusions about the therapeutic benefit...
Hofmeijer, Jeannette, Amelink, G Johan, Algra, Ale, Van Gijn, Jan, Macleod, Malcolm R, Kappelle, L Jaap, ...
Abstract Background Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite maximal conservative treatment, the case fatality rate may be as high...
Mineralocorticoid receptor expression and increased survival following neuronal injury. (2003)
Macleod, Malcolm R, Johansson, Inga-Maj, Söderström, Ingegerd, Lai, Maggie, Gidö, Gunilla, Wieloch, Tadeusz, ...
Abstract is not available
Hofmeijer, Jeannette, Amelink, G Johan, Algra, Ale, Van Gijn, Jan, Macleod, Malcolm R, Kappelle, L Jaap, ...