Sensitive Sequencing Method for KRAS Mutation Detection by Pyrosequencing
Ogino, Shuji, Kawasaki, Takako, Brahmandam, Mohan, Yan, Liying, Cantor, Mami, Namgyal, Chungdak, ...
Both benign and malignant tumors represent heterogenous tissue containing tumor cells and non-neoplastic mesenchymal and inflammatory cells. To detect a minority of mutant KRAS alleles among abundant...
Ogino, Shuji, Kawasaki, Takako, Brahmandam, Mohan, Cantor, Mami, Kirkner, Gregory J., Spiegelman, Donna, ...
Assays to measure DNA methylation, which are important in epigenetic research and clinical diagnostics, typically rely on conversion of unmethylated cytosine to uracil by sodium bisulfite. However,...