Mandy Krumbiegel

Simian Immunodeficiency Virus Utilizes Human and Sooty Mangabey but Not Rhesus Macaque STRL33 for Efficient Entry

Pöhlmann, Stefan, Lee, Benhur, Meister, Silke, Krumbiegel, Mandy, Leslie, George, Doms, Robert W., ...

It has been established that many simian immunodeficiency virus (SIV) isolates utilize the orphan receptors GPR15 and STRL33 about as efficiently as the chemokine receptor CCR5 for entry into target...

Modulation of Different Human Immunodeficiency Virus Type 1 Nef Functions during Progression to AIDS

Carl, Silke, Greenough, Thomas C., Krumbiegel, Mandy, Greenberg, Michael, Skowronski, Jacek, Sullivan, John L., ...

The human immunodeficiency virus type 1 (HIV-1) Nef protein has several independent functions that might contribute to efficient viral replication in vivo. Since HIV-1 adapts rapidly to its host...

Amino Acid 324 in the Simian Immunodeficiency Virus SIVmac V3 Loop Can Confer CD4 Independence and Modulate the Interaction with CCR5 and Alternative Coreceptors

Pöhlmann, Stefan, Davis, Carl, Meister, Silke, Leslie, George J., Otto, Claas, Reeves, Jacqueline D., ...

The V3 loop of the simian immunodeficiency virus (SIV) envelope protein (Env) largely determines interactions with viral coreceptors. To define amino acids in V3 that are critical for coreceptor...

S Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Mediates Entry into Hepatoma Cell Lines and Is Targeted by Neutralizing Antibodies in Infected Patients

Hofmann, Heike, Hattermann, Kim, Marzi, Andrea, Gramberg, Thomas, Geier, Martina, Krumbiegel, Mandy, ...

The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) causes severe pneumonia with a fatal outcome in approximately 10% of patients. SARS-CoV is not closely related to other...

DC-SIGN and DC-SIGNR Interact with the Glycoprotein of Marburg Virus and the S Protein of Severe Acute Respiratory Syndrome Coronavirus

Marzi, Andrea, Gramberg, Thomas, Simmons, Graham, Möller, Peggy, Rennekamp, Andrew J., Krumbiegel, Mandy, ...

The lectins DC-SIGN and DC-SIGNR can augment viral infection; however, the range of pathogens interacting with these attachment factors is incompletely defined. Here we show that DC-SIGN and DC-SIGNR...

Simian Immunodeficiency Virus Utilizes Human and Sooty Mangabey but Not Rhesus Macaque STRL33 for Efficient Entry

Pöhlmann, Stefan, Lee, Benhur, Meister, Silke, Krumbiegel, Mandy, Leslie, George, Doms, Robert W., ...

It has been established that many simian immunodeficiency virus (SIV) isolates utilize the orphan receptors GPR15 and STRL33 about as efficiently as the chemokine receptor CCR5 for entry into target...

Modulation of Different Human Immunodeficiency Virus Type 1 Nef Functions during Progression to AIDS

Carl, Silke, Greenough, Thomas C., Krumbiegel, Mandy, Greenberg, Michael, Skowronski, Jacek, Sullivan, John L., ...

The human immunodeficiency virus type 1 (HIV-1) Nef protein has several independent functions that might contribute to efficient viral replication in vivo. Since HIV-1 adapts rapidly to its host...

Amino Acid 324 in the Simian Immunodeficiency Virus SIVmac V3 Loop Can Confer CD4 Independence and Modulate the Interaction with CCR5 and Alternative Coreceptors

Pöhlmann, Stefan, Davis, Carl, Meister, Silke, Leslie, George J., Otto, Claas, Reeves, Jacqueline D., ...

The V3 loop of the simian immunodeficiency virus (SIV) envelope protein (Env) largely determines interactions with viral coreceptors. To define amino acids in V3 that are critical for coreceptor...

S Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Mediates Entry into Hepatoma Cell Lines and Is Targeted by Neutralizing Antibodies in Infected Patients

Hofmann, Heike, Hattermann, Kim, Marzi, Andrea, Gramberg, Thomas, Geier, Martina, Krumbiegel, Mandy, ...

The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) causes severe pneumonia with a fatal outcome in approximately 10% of patients. SARS-CoV is not closely related to other...

DC-SIGN and DC-SIGNR Interact with the Glycoprotein of Marburg Virus and the S Protein of Severe Acute Respiratory Syndrome Coronavirus

Marzi, Andrea, Gramberg, Thomas, Simmons, Graham, Möller, Peggy, Rennekamp, Andrew J., Krumbiegel, Mandy, ...

The lectins DC-SIGN and DC-SIGNR can augment viral infection; however, the range of pathogens interacting with these attachment factors is incompletely defined. Here we show that DC-SIGN and DC-SIGNR...