Manfred Kraus

Basal Immunoglobulin Signaling Actively Maintains Developmental Stage in Immature B Cells (2005)

Lina E. Tze, Brian R. Schram, Kong-Peng Lam, Kristin A. Hogquist, Keli L. Hippen, Jiabin Liu, ...

Gene rearrangement is a hallmark of B cell maturation. By interrupting basal cell signaling through the rearranged IgM receptor, immature B cells "back-differentiate" to an earlier stage in their...

Basal Immunoglobulin Signaling Actively Maintains Developmental Stage in Immature B Cells (2005)

Lina E. Tze, Brian R. Schram, Kong-Peng Lam, Kristin A. Hogquist, Keli L. Hippen, Jiabin Liu, ...

In developing B lymphocytes, a successful V(D)J heavy chain (HC) immunoglobulin (Ig) rearrangement establishes HC allelic exclusion and signals pro-B cells to advance in development to the pre-B...

The kyphoscoliosis (ky) mouse is deficient in hypertrophic responses and is caused by a mutation in a novel muscle-specific protein (2001)

Blanco, Gonzalo, Coulton, GaryR., Biggin, Andrew, Grainge, Christopher, Moss, Jill, Barrett, Michael, ...

The ky mouse mutant exhibits a primary degenerative myopathy preceding chronic thoraco-lumbar kyphoscoliosis. The histopathology of the ky mutant suggests that Ky protein activity is crucial for...

The kyphoscoliosis (ky) mouse is deficient in hypertrophic responses and is caused by a mutation in a novel muscle-specific protein (2001)

Blanco, Gonzalo, Coulton, Gary R., Biggin, Andrew, Grainge, Christopher, Moss, Jill, Barrett, Michael, ...

The ky mouse mutant exhibits a primary degenerative myopathy preceding chronic thoraco-lumbar kyphoscoliosis. The histopathology of the ky mutant suggests that Ky protein activity is crucial for...

Ein Beitrag zur Simulation kontinuierlicher Systeme. (1984)

Kraus, Manfred.

Ilmenau, Techn. Hochsch., Diss. B, 1984 (Nicht f.d. Austausch).

Zur Larvalsystematik der Blattwespen . (1955)

Kraus, Manfred.

Erlangen, Naturwiss. F., Diss. v. 25. Juli 1955 (Nicht f. d. Aust.).

Basal Immunoglobulin Signaling Actively Maintains Developmental Stage in Immature B Cells

Tze, Lina E, Schram, Brian R, Lam, Kong-Peng, Hogquist, Kristin A, Hippen, Keli L, Liu, Jiabin, ...

In developing B lymphocytes, a successful V(D)J heavy chain (HC) immunoglobulin (Ig) rearrangement establishes HC allelic exclusion and signals pro-B cells to advance in development to the pre-B...

Basal Immunoglobulin Signaling Actively Maintains Developmental Stage in Immature B Cells

Tze, Lina E, Schram, Brian R, Lam, Kong-Peng, Hogquist, Kristin A, Hippen, Keli L, Liu, Jiabin, ...

In developing B lymphocytes, a successful V(D)J heavy chain (HC) immunoglobulin (Ig) rearrangement establishes HC allelic exclusion and signals pro-B cells to advance in development to the pre-B...

IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Igα/β

Waisman, Ari, Kraus, Manfred, Seagal, Jane, Ghosh, Snigdha, Melamed, Doron, Song, Jian, ...

We describe a mouse strain in which B cell development relies either on the expression of membrane-bound immunoglobulin (Ig) γ1 or μ heavy chains. Progenitor cells expressing γ1 chains from the...

A B Cell Receptor with Two Igα Cytoplasmic Domains Supports Development of Mature But Anergic B Cells

Reichlin, Amy, Gazumyan, Anna, Nagaoka, Hitoshi, Kirsch, Kathrin H., Kraus, Manfred, Rajewsky, Klaus, ...

B cell receptor (BCR) signaling is mediated through immunoglobulin (Ig)α and Igβ a membrane-bound heterodimer. Igα and Igβ are redundant in their ability to support early B cell development, but...

Interference with Immunoglobulin (Ig)α Immunoreceptor Tyrosine–Based Activation Motif (Itam) Phosphorylation Modulates or Blocks B Cell Development, Depending on the Availability of an Igβ Cytoplasmic Tail

Kraus, Manfred, Pao, Lily I., Reichlin, Amy, Hu, Yun, Canono, Beth, Cambier, John C., ...

To determine the function of immunoglobulin (Ig)α immunoreceptor tyrosine–based activation motif (ITAM) phosphorylation, we generated mice in which Igα ITAM tyrosines were replaced by...

B Cell Development Is Arrested at the Immature B Cell Stage in Mice Carrying a Mutation in the Cytoplasmic Domain of Immunoglobulin β

Reichlin, Amy, Hu, Yun, Meffre, Eric, Nagaoka, Hitoshi, Gong, Shiaoching, Kraus, Manfred, ...

The B cell receptor (BCR) regulates B cell development and function through immunoglobulin (Ig)α and Igβ, a pair of membrane-bound Ig superfamily proteins, each of which contains a single...